PL394208A1 - Nowe pochodne benzo[g]chinoliny, kompozycje farmaceutyczne je zawierające oraz zastosowania farmaceutyczne tych związków - Google Patents

Nowe pochodne benzo[g]chinoliny, kompozycje farmaceutyczne je zawierające oraz zastosowania farmaceutyczne tych związków

Info

Publication number: PL394208A1
Authority: PL; Poland
Prior art keywords: benzo; quinoline; compounds; compositions containing; pharmaceutical
Prior art date: 2002-03-07

Application number

PL394208A

Other languages

English (en)

Other versions

PL215012B1 (pl

Inventor

Peter Gull

Villar Esteban Pombo

Original Assignee

Novartis Ag

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2002-03-07

Filing date

2003-03-06

Publication date

2011-08-16

2003-03-06 Application filed by Novartis Ag filed Critical Novartis Ag

2011-08-16 Publication of PL394208A1 publication Critical patent/PL394208A1/pl

2013-10-31 Publication of PL215012B1 publication Critical patent/PL215012B1/pl

Links

RFQDDXWZZVRLKO-UHFFFAOYSA-N benzo[g]quinoline Chemical class N1=CC=CC2=CC3=CC=CC=C3C=C21 RFQDDXWZZVRLKO-UHFFFAOYSA-N 0.000 title 1
150000001875 compounds Chemical class 0.000 title 1
239000008194 pharmaceutical composition Substances 0.000 title 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
- A61P27/06—Antiglaucoma agents or miotics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
- A61P27/10—Ophthalmic agents for accommodation disorders, e.g. myopia
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D513/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00
- C07D513/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00 in which the condensed system contains two hetero rings
- C07D513/04—Ortho-condensed systems

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Pharmacology & Pharmacy (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Engineering & Computer Science (AREA)
Ophthalmology & Optometry (AREA)
Bioinformatics & Cheminformatics (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Plural Heterocyclic Compounds (AREA)
Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)

PL394208A 2002-03-07 2003-03-06 Nowe pochodne benzo[g]chinoliny, kompozycje farmaceutyczne je zawierajace oraz zastosowania farmaceutyczne tych zwiazków PL215012B1 (pl)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
EP02005117		2002-03-07
EP02005115		2002-03-07

Publications (2)

Publication Number	Publication Date
PL394208A1 true PL394208A1 (pl)	2011-08-16
PL215012B1 PL215012B1 (pl)	2013-10-31

Family

ID=27790094

Family Applications (2)

Application Number	Title	Priority Date	Filing Date
PL370915A PL210336B1 (pl)	2002-03-07	2003-03-06	Pochodna benzo(g)chinoliny, kompozycja farmaceutyczna zawierająca tę pochodną oraz zastosowanie tej pochodnej benzo(g)chinoliny
PL394208A PL215012B1 (pl)	2002-03-07	2003-03-06	Nowe pochodne benzo[g]chinoliny, kompozycje farmaceutyczne je zawierajace oraz zastosowania farmaceutyczne tych zwiazków

Family Applications Before (1)

Application Number	Title	Priority Date	Filing Date
PL370915A PL210336B1 (pl)	2002-03-07	2003-03-06	Pochodna benzo(g)chinoliny, kompozycja farmaceutyczna zawierająca tę pochodną oraz zastosowanie tej pochodnej benzo(g)chinoliny

Country Status (28)

Country	Link
US (2)	US7399768B2 (pl)
EP (1)	EP1480970B1 (pl)
JP (2)	JP2005519117A (pl)
KR (1)	KR101027977B1 (pl)
CN (2)	CN1939915A (pl)
AR (1)	AR038730A1 (pl)
AU (1)	AU2003219023B2 (pl)
BR (1)	BR0308201A (pl)
CA (2)	CA2477720C (pl)
CO (1)	CO5611196A2 (pl)
CY (1)	CY1106409T1 (pl)
DE (1)	DE60311233T2 (pl)
DK (1)	DK1480970T3 (pl)
EC (1)	ECSP045271A (pl)
EG (1)	EG24415A (pl)
ES (1)	ES2279100T3 (pl)
IL (1)	IL163769A0 (pl)
MX (1)	MXPA04008666A (pl)
MY (1)	MY134325A (pl)
NO (1)	NO20044117L (pl)
NZ (1)	NZ534732A (pl)
PE (1)	PE20030927A1 (pl)
PL (2)	PL210336B1 (pl)
PT (1)	PT1480970E (pl)
RU (1)	RU2345991C2 (pl)
SI (1)	SI1480970T1 (pl)
TW (1)	TW200406401A (pl)
WO (1)	WO2003074511A1 (pl)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
PT1757601E (pt) *	2002-03-07	2009-10-23	Novartis Ag	Derivados de quinolina e sua utilização em glaucoma e miopia
CR20200225A (es)	2017-11-24	2020-07-25	H Lundbeck As	Nuevos fármacos de catecolamina para uso en el tratamiento de la enfermedad de parkinson
US11111263B2 (en)	2019-05-20	2021-09-07	H. Lundbeck A/S	Process for the manufacture of (2S,3S,4S,5R,6S)-3,4,5-trihydroxy-6-(((4aR,10aR)-7-hydroxy-1-propyl-1,2,3,4,4a,5,10,10a-octahydrobenzo[g]quinolin-6-yl)oxy)tetrahydro-2H-pyran-2-carboxylic acid
US11104697B2 (en)	2019-05-20	2021-08-31	H. Lundbeck A/S	Process for the manufacture of (2S,3S,4S,5R,6S)-3,4,5-trihydroxy-6-(((4AR,10AR)-7-hydroxy-1- propyl-1,2,3,4,4A,5,10,10A-octahydrobenzo[g]quinolin-6-yl)oxy)tetrahydro-2H-pyran-2-carboxylic acid
US11130775B2 (en)	2019-05-20	2021-09-28	H. Lundbeck A/S	Solid forms of (2S,3S,4S,5R,6S)-3,4,5-trihydroxy-6-(((4aR,10aR)-7-hydroxy-1-propyl-1,2,3,4,4A,5,10,10A-octahydrobenzo[g]quinolin-6-yl)oxy)tetrahydro-2H-pyran-2-carboxylic acid
US11168056B2 (en)	2019-05-20	2021-11-09	H. Lundbeck A/S	Process for the manufacturing of (6aR,10aR)-7-propyl-6,6a,7,8,9,10,10a,11-octahydro-[1,3]dioxolo[4′,5′:5,6]benzo[1,2-G]quinoline and (4aR,10aR)-1-propyl-1,2,3,4,4a,5,10,10a-octahydro-benzo[G]quinoline-6,7-diol
EP3972971A1 (en)	2019-05-21	2022-03-30	H. Lundbeck A/S	New catecholamine prodrugs for use in the treatment of parkinson's diseases
WO2020234277A1 (en)	2019-05-21	2020-11-26	H. Lundbeck A/S	Catecholamine carbamate prodrugs for use in the treatment of parkinson s disease
JP7641234B2 (ja)	2019-05-21	2025-03-06	ハー・ルンドベック・アクチエゼルスカベット	パーキンソン病の治療に使用するための新規なカテコールアミンプロドラッグ
WO2020234276A1 (en)	2019-05-21	2020-11-26	H. Lundbeck A/S	New catecholamine prodrugs for use in the treatment of parkinson's disease

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
IL100555A (en) *	1991-02-07	2000-08-31	Hoechst Marion Roussel Inc	N-substituted quinoline derivatives their preparation their use for the preparation of medicaments and the pharmaceutical compositions containing them
GB9326010D0 (en) *	1993-12-21	1994-02-23	Sandoz Ltd	Improvements in or relating to organic compounds
TW378209B (en) *	1996-07-08	2000-01-01	Novartis Ag	Benzo[g]quinoline derivatives, their preparation and the pharmaceutical composition containing them
PE20030240A1 (es) *	2001-07-09	2003-04-16	Novartis Ag	DERIVADOS DE BENZO [g] QUINOLINA

2003
- 2003-03-03 EG EG2003030215A patent/EG24415A/xx active
- 2003-03-05 TW TW092104671A patent/TW200406401A/zh unknown
- 2003-03-05 PE PE2003000212A patent/PE20030927A1/es not_active Application Discontinuation
- 2003-03-05 AR ARP030100740A patent/AR038730A1/es unknown
- 2003-03-06 PL PL370915A patent/PL210336B1/pl unknown
- 2003-03-06 EP EP03714784A patent/EP1480970B1/en not_active Expired - Lifetime
- 2003-03-06 CN CNA2006101357990A patent/CN1939915A/zh active Pending
- 2003-03-06 PL PL394208A patent/PL215012B1/pl unknown
- 2003-03-06 ES ES03714784T patent/ES2279100T3/es not_active Expired - Lifetime
- 2003-03-06 AU AU2003219023A patent/AU2003219023B2/en not_active Ceased
- 2003-03-06 WO PCT/EP2003/002321 patent/WO2003074511A1/en not_active Ceased
- 2003-03-06 NZ NZ534732A patent/NZ534732A/en unknown
- 2003-03-06 PT PT03714784T patent/PT1480970E/pt unknown
- 2003-03-06 IL IL16376903A patent/IL163769A0/xx unknown
- 2003-03-06 JP JP2003572979A patent/JP2005519117A/ja active Pending
- 2003-03-06 DK DK03714784T patent/DK1480970T3/da active
- 2003-03-06 BR BR0308201-6A patent/BR0308201A/pt not_active Application Discontinuation
- 2003-03-06 KR KR1020047012409A patent/KR101027977B1/ko not_active Expired - Fee Related
- 2003-03-06 CA CA2477720A patent/CA2477720C/en not_active Expired - Fee Related
- 2003-03-06 CA CA2706618A patent/CA2706618A1/en not_active Abandoned
- 2003-03-06 US US10/506,232 patent/US7399768B2/en not_active Expired - Fee Related
- 2003-03-06 RU RU2004129767/04A patent/RU2345991C2/ru not_active IP Right Cessation
- 2003-03-06 CN CNB038053608A patent/CN1293070C/zh not_active Expired - Fee Related
- 2003-03-06 DE DE60311233T patent/DE60311233T2/de not_active Expired - Lifetime
- 2003-03-06 MX MXPA04008666A patent/MXPA04008666A/es active IP Right Grant
- 2003-03-06 SI SI200330755T patent/SI1480970T1/sl unknown
- 2003-03-07 MY MYPI20030808A patent/MY134325A/en unknown
2004
- 2004-09-02 EC EC2004005271A patent/ECSP045271A/es unknown
- 2004-09-15 CO CO04091781A patent/CO5611196A2/es not_active Application Discontinuation
- 2004-09-28 NO NO20044117A patent/NO20044117L/no not_active Application Discontinuation
2007
- 2007-03-22 CY CY20071100405T patent/CY1106409T1/el unknown
2008
- 2008-06-12 US US12/137,819 patent/US20080255176A1/en not_active Abandoned
2010
- 2010-02-04 JP JP2010022863A patent/JP2010095550A/ja active Pending

Also Published As

Publication number	Publication date
CN1939915A (zh)	2007-04-04
CY1106409T1 (el)	2011-10-12
SI1480970T1 (sl)	2007-06-30
IL163769A0 (en)	2005-12-18
ES2279100T3 (es)	2007-08-16
AU2003219023B2 (en)	2006-11-30
NZ534732A (en)	2006-05-26
PL215012B1 (pl)	2013-10-31
JP2005519117A (ja)	2005-06-30
HK1071364A1 (en)	2005-07-15
PL210336B1 (pl)	2012-01-31
US20050234085A1 (en)	2005-10-20
CA2706618A1 (en)	2003-09-12
AR038730A1 (es)	2005-01-26
DK1480970T3 (da)	2007-03-05
PL370915A1 (pl)	2005-06-13
MY134325A (en)	2007-12-31
PT1480970E (pt)	2007-03-30
MXPA04008666A (es)	2004-12-06
US20080255176A1 (en)	2008-10-16
JP2010095550A (ja)	2010-04-30
CA2477720C (en)	2010-09-21
DE60311233T2 (de)	2007-11-15
PE20030927A1 (es)	2003-12-26
CO5611196A2 (es)	2006-02-28
KR20040089615A (ko)	2004-10-21
CN1639148A (zh)	2005-07-13
KR101027977B1 (ko)	2011-04-13
RU2004129767A (ru)	2005-06-27
CA2477720A1 (en)	2003-09-12
CN1293070C (zh)	2007-01-03
EP1480970A1 (en)	2004-12-01
WO2003074511A1 (en)	2003-09-12
ECSP045271A (es)	2004-10-26
DE60311233D1 (de)	2007-03-08
NO20044117L (no)	2004-09-28
EP1480970B1 (en)	2007-01-17
TW200406401A (en)	2004-05-01
RU2345991C2 (ru)	2009-02-10
BR0308201A (pt)	2005-01-04
AU2003219023A1 (en)	2003-09-16
US7399768B2 (en)	2008-07-15
EG24415A (en)	2009-05-25

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