PL3956292T3 - Sposób wytwarzania enancjomerycznie czystej norepinefryny - Google Patents
Sposób wytwarzania enancjomerycznie czystej norepinefrynyInfo
- Publication number
- PL3956292T3 PL3956292T3 PL20717602.5T PL20717602T PL3956292T3 PL 3956292 T3 PL3956292 T3 PL 3956292T3 PL 20717602 T PL20717602 T PL 20717602T PL 3956292 T3 PL3956292 T3 PL 3956292T3
- Authority
- PL
- Poland
- Prior art keywords
- norepinephrine
- preparation
- enantiomerically pure
- enantiomerically
- pure
- Prior art date
Links
- SFLSHLFXELFNJZ-QMMMGPOBSA-N (-)-norepinephrine Chemical compound NC[C@H](O)C1=CC=C(O)C(O)=C1 SFLSHLFXELFNJZ-QMMMGPOBSA-N 0.000 title 1
- 229960002748 norepinephrine Drugs 0.000 title 1
- SFLSHLFXELFNJZ-UHFFFAOYSA-N norepinephrine Natural products NCC(O)C1=CC=C(O)C(O)=C1 SFLSHLFXELFNJZ-UHFFFAOYSA-N 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C213/00—Preparation of compounds containing amino and hydroxy, amino and etherified hydroxy or amino and esterified hydroxy groups bound to the same carbon skeleton
- C07C213/08—Preparation of compounds containing amino and hydroxy, amino and etherified hydroxy or amino and esterified hydroxy groups bound to the same carbon skeleton by reactions not involving the formation of amino groups, hydroxy groups or etherified or esterified hydroxy groups
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C221/00—Preparation of compounds containing amino groups and doubly-bound oxygen atoms bound to the same carbon skeleton
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J23/00—Catalysts comprising metals or metal oxides or hydroxides, not provided for in group B01J21/00
- B01J23/38—Catalysts comprising metals or metal oxides or hydroxides, not provided for in group B01J21/00 of noble metals
- B01J23/40—Catalysts comprising metals or metal oxides or hydroxides, not provided for in group B01J21/00 of noble metals of the platinum group metals
- B01J23/44—Palladium
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J31/00—Catalysts comprising hydrides, coordination complexes or organic compounds
- B01J31/16—Catalysts comprising hydrides, coordination complexes or organic compounds containing coordination complexes
- B01J31/18—Catalysts comprising hydrides, coordination complexes or organic compounds containing coordination complexes containing nitrogen, phosphorus, arsenic or antimony as complexing atoms, e.g. in pyridine ligands, or in resonance therewith, e.g. in isocyanide ligands C=N-R or as complexed central atoms
- B01J31/1805—Catalysts comprising hydrides, coordination complexes or organic compounds containing coordination complexes containing nitrogen, phosphorus, arsenic or antimony as complexing atoms, e.g. in pyridine ligands, or in resonance therewith, e.g. in isocyanide ligands C=N-R or as complexed central atoms the ligands containing nitrogen
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J31/00—Catalysts comprising hydrides, coordination complexes or organic compounds
- B01J31/16—Catalysts comprising hydrides, coordination complexes or organic compounds containing coordination complexes
- B01J31/22—Organic complexes
- B01J31/2282—Unsaturated compounds used as ligands
- B01J31/2295—Cyclic compounds, e.g. cyclopentadienyls
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C223/00—Compounds containing amino and —CHO groups bound to the same carbon skeleton
- C07C223/02—Compounds containing amino and —CHO groups bound to the same carbon skeleton having amino groups bound to acyclic carbon atoms of the carbon skeleton
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J2531/00—Additional information regarding catalytic systems classified in B01J31/00
- B01J2531/80—Complexes comprising metals of Group VIII as the central metal
- B01J2531/82—Metals of the platinum group
- B01J2531/821—Ruthenium
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
- C07B2200/00—Indexing scheme relating to specific properties of organic compounds
- C07B2200/07—Optical isomers
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C2601/00—Systems containing only non-condensed rings
- C07C2601/12—Systems containing only non-condensed rings with a six-membered ring
- C07C2601/16—Systems containing only non-condensed rings with a six-membered ring the ring being unsaturated
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Engineering & Computer Science (AREA)
- Materials Engineering (AREA)
- Inorganic Chemistry (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Catalysts (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP19170053.3A EP3725765A1 (en) | 2019-04-18 | 2019-04-18 | A process for the preparation of enantiomerically pure norepinephrine |
| PCT/EP2020/059438 WO2020212157A1 (en) | 2019-04-18 | 2020-04-02 | A process for the preparation of enantiomerically pure norepinephrine |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| PL3956292T3 true PL3956292T3 (pl) | 2023-08-07 |
Family
ID=66239794
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PL20717602.5T PL3956292T3 (pl) | 2019-04-18 | 2020-04-02 | Sposób wytwarzania enancjomerycznie czystej norepinefryny |
Country Status (7)
| Country | Link |
|---|---|
| US (1) | US11390579B2 (pl) |
| EP (2) | EP3725765A1 (pl) |
| JP (1) | JP2022529980A (pl) |
| CN (1) | CN113748101B (pl) |
| ES (1) | ES2948860T3 (pl) |
| PL (1) | PL3956292T3 (pl) |
| WO (1) | WO2020212157A1 (pl) |
Families Citing this family (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN112225665A (zh) * | 2020-10-28 | 2021-01-15 | 合肥亿帆生物制药有限公司 | 一种重酒石酸去甲肾上腺素制备方法 |
| CN113735720A (zh) * | 2021-10-26 | 2021-12-03 | 成都倍特药业股份有限公司 | 一种(±)-肾上腺素的制备方法 |
| CN115850095A (zh) * | 2022-12-27 | 2023-03-28 | 武汉嘉诺康医药技术有限公司 | 一种重酒石酸去甲肾上腺素的制备方法 |
| CN116410096A (zh) * | 2023-02-23 | 2023-07-11 | 河北广祥制药有限公司 | 一种重酒石酸去甲肾上腺素的制备方法 |
| ES2999182B2 (es) * | 2023-08-24 | 2025-12-18 | Moehs Iberica Sl | Procedimiento de síntesis de (1R)-2-(dibencilamino)-1-(3,4-dibenciloxifenil)etanol, nuevos intermedios de dicho procedimiento y uso del producto en la síntesis de noradrenalina |
| CN117229155A (zh) * | 2023-09-18 | 2023-12-15 | 绪必迪药业(沧州)有限公司 | 一种dl去甲肾上腺素的制备方法 |
| CN117003651B (zh) * | 2023-09-28 | 2024-01-02 | 广东嘉博制药有限公司 | 一种l-肾上腺素的制备方法 |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US2774789A (en) | 1947-10-24 | 1956-12-18 | Sterling Drug Inc | 1-arterenol and its acid-addition salts and preparation thereof |
| US2786871A (en) | 1954-03-26 | 1957-03-26 | Winterhalder Ludwig | Process for the preparation of aminomethyl-(monohydroxyphenyl)-ketones |
| DE19938709C1 (de) * | 1999-08-14 | 2001-01-18 | Boehringer Ingelheim Pharma | Verfahren zur Herstellung von Adrenalin |
| WO2013008247A1 (en) | 2011-07-13 | 2013-01-17 | Neon Laboratories Ltd. | Process for preparation of (dl) -norepinephrine acid addition salt, a key intermediate of (r) - (-) - norepinephrine |
| CN108069863B (zh) | 2016-11-17 | 2020-08-11 | 武汉武药制药有限公司 | 一种合成去甲肾上腺素的方法 |
-
2019
- 2019-04-18 EP EP19170053.3A patent/EP3725765A1/en not_active Withdrawn
-
2020
- 2020-04-02 WO PCT/EP2020/059438 patent/WO2020212157A1/en not_active Ceased
- 2020-04-02 ES ES20717602T patent/ES2948860T3/es active Active
- 2020-04-02 CN CN202080029469.1A patent/CN113748101B/zh active Active
- 2020-04-02 US US17/594,409 patent/US11390579B2/en active Active
- 2020-04-02 JP JP2021562053A patent/JP2022529980A/ja active Pending
- 2020-04-02 EP EP20717602.5A patent/EP3956292B1/en active Active
- 2020-04-02 PL PL20717602.5T patent/PL3956292T3/pl unknown
Also Published As
| Publication number | Publication date |
|---|---|
| EP3956292B1 (en) | 2023-04-26 |
| EP3725765A1 (en) | 2020-10-21 |
| ES2948860T3 (es) | 2023-09-20 |
| WO2020212157A1 (en) | 2020-10-22 |
| JP2022529980A (ja) | 2022-06-27 |
| CN113748101B (zh) | 2024-04-02 |
| CN113748101A (zh) | 2021-12-03 |
| EP3956292A1 (en) | 2022-02-23 |
| US20220089520A1 (en) | 2022-03-24 |
| US11390579B2 (en) | 2022-07-19 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| PL3956292T3 (pl) | Sposób wytwarzania enancjomerycznie czystej norepinefryny | |
| GB2589908B (en) | A method for preparing a geoolymer composition | |
| SI3863685T1 (sl) | Postopek za proizvodnjo generatorja radija-228 z visoko vsebnostjo | |
| PL3930877T3 (pl) | Wytwarzanie stężonego zużytego dializatu | |
| SG11202108238VA (en) | Process for the preparation of methionine | |
| SG11202106938VA (en) | Process for preparing microcapsules | |
| IL289904A (en) | A process for preparing biphenylamines | |
| NO20190144A1 (en) | A process for production of aluminium | |
| IL275381A (en) | A process for the preparation of Crisborole | |
| ZA202211800B (en) | Process for the preparation of a flavouring | |
| IL289971A (en) | Improved methods for the production of plants | |
| IL283633A (en) | A process for preparing a cyclic dinucleotide | |
| IL276557A (en) | A process for making metformin | |
| HUE064405T2 (hu) | Eljárás nitrogén-oxid donor prosztaglandin analóg elõállítására | |
| PL3802529T3 (pl) | Sposób wytwarzania palbocyklibu | |
| IL286054A (en) | A process for the preparation of a modified imidazoquinoline | |
| ZA202102159B (en) | Process for the preparation of a flavouring | |
| HUE073252T2 (hu) | Eljárás melfalán szintézisére | |
| HUE064510T2 (hu) | Eljárás N-alkil-hidroxilammónium sókat tartalmazó keverék tisztítására | |
| SG11201911909UA (en) | Synthesis method for producing enantiomerically pure cis-imidazoline compounds for pharmaceutical use | |
| HK40065827A (en) | Process for preparing enantiomerically enriched jak inhibitors | |
| EP4013502B8 (en) | Process for the preparation of a pyrimidino-diazepine derivative | |
| PL3725774T3 (pl) | Sposób wytwarzania środka farmaceutycznego | |
| PL3788886T3 (pl) | Kompozycja odpowiednia do zastąpienia syropu glukozowego | |
| AU2019900916A0 (en) | A method for the production of 2-substituted-3H-quinazolin-4-ones-I |