PL402199A1 - Sposób wytwarzania (1' R,3R,4R)-4-acetoksy-3-(1' -(tert-butylodimetylosililoksy)etylo)-2-azetydynonu prekursora synetzy antybiotyków karbapenemowych - Google Patents

Sposób wytwarzania (1' R,3R,4R)-4-acetoksy-3-(1' -(tert-butylodimetylosililoksy)etylo)-2-azetydynonu prekursora synetzy antybiotyków karbapenemowych

Info

Publication number
PL402199A1
PL402199A1 PL402199A PL40219912A PL402199A1 PL 402199 A1 PL402199 A1 PL 402199A1 PL 402199 A PL402199 A PL 402199A PL 40219912 A PL40219912 A PL 40219912A PL 402199 A1 PL402199 A1 PL 402199A1
Authority
PL
Poland
Prior art keywords
azetidinone
butyldimethylsilyloxy
acetoxy
tert
ethyl
Prior art date
Application number
PL402199A
Other languages
English (en)
Other versions
PL227494B1 (pl
Inventor
Barbara Grzeszczyk
Sebastian Stecko
Bartłomiej Furman
Marek Chmielewski
Original Assignee
Instytut Chemii Organicznej Polskiej Akademii Nauk
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Instytut Chemii Organicznej Polskiej Akademii Nauk filed Critical Instytut Chemii Organicznej Polskiej Akademii Nauk
Priority to PL402199A priority Critical patent/PL227494B1/pl
Priority to PCT/IB2013/061211 priority patent/WO2014097257A1/en
Publication of PL402199A1 publication Critical patent/PL402199A1/pl
Publication of PL227494B1 publication Critical patent/PL227494B1/pl

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D205/00—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom
    • C07D205/02—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings
    • C07D205/06—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C07D205/08—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with one oxygen atom directly attached in position 2, e.g. beta-lactams

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

Abstract

Przedmiotem wynalazku jest sposób wytwarzania (1'R,3R,4R)-4-acetoksy-3-(1'-(tert-butylodimetylosililoksy) etylo)-2-azetydynonu o wzorze (1), będącego podstawowym chiralnym blokiem budulcowym w syntezie antybiotyków karbapenemowych.
PL402199A 2012-12-21 2012-12-21 Sposób wytwarzania pochodnej 2-azetydynonowej i sposób wytwarzania związków pośrednich PL227494B1 (pl)

Priority Applications (2)

Application Number Priority Date Filing Date Title
PL402199A PL227494B1 (pl) 2012-12-21 2012-12-21 Sposób wytwarzania pochodnej 2-azetydynonowej i sposób wytwarzania związków pośrednich
PCT/IB2013/061211 WO2014097257A1 (en) 2012-12-21 2013-12-20 A method of preparation of (1'r,3r,4r)-4-acetoxy-3-(1'-(tert-butyldimethylsilyloxy)ethyl)-2-azetidinone, a precursor for carbapenem antibiotics synthesis

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
PL402199A PL227494B1 (pl) 2012-12-21 2012-12-21 Sposób wytwarzania pochodnej 2-azetydynonowej i sposób wytwarzania związków pośrednich

Publications (2)

Publication Number Publication Date
PL402199A1 true PL402199A1 (pl) 2014-06-23
PL227494B1 PL227494B1 (pl) 2017-12-29

Family

ID=50070619

Family Applications (1)

Application Number Title Priority Date Filing Date
PL402199A PL227494B1 (pl) 2012-12-21 2012-12-21 Sposób wytwarzania pochodnej 2-azetydynonowej i sposób wytwarzania związków pośrednich

Country Status (2)

Country Link
PL (1) PL227494B1 (pl)
WO (1) WO2014097257A1 (pl)

Family Cites Families (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4395418A (en) 1980-06-06 1983-07-26 Sankyo Company Limited Penem-3-carboxylic acid derivatives
GB8321004D0 (en) 1983-08-04 1983-09-07 Erba Farmitalia Azetidinones
GB8416066D0 (en) 1984-06-23 1984-07-25 Consiglio Nazionale Ricerche Stereospecific process
US4791198A (en) 1984-07-05 1988-12-13 Kanegafuchi Kagaku Kogyo Kabushiki Kaisha Beta-lactam compound and preparation thereof
CA1256443A (en) 1984-07-05 1989-06-27 Takehisa Ohashi Process for preparing 4-acetoxy-3- hydroxyethylazetidin-2-one derivatives
JPS62164689A (ja) 1986-01-14 1987-07-21 Kanegafuchi Chem Ind Co Ltd 新規β−ラクタム化合物及びその製造法
US4861877A (en) 1984-07-05 1989-08-29 Kanegafuchi Kagaku Kogyo Kabushiki Kaisha Process for preparing 4-acetoxy-3-hydroxyethylazetidin-2-one derivatives
JPH066570B2 (ja) 1985-10-07 1994-01-26 鐘淵化学工業株式会社 ４−アセトキシ−３−ヒドロキシエチルアゼチジン−２−オン誘導体の製造法
JPS62195359A (ja) 1986-02-22 1987-08-28 Kanegafuchi Chem Ind Co Ltd ４−アセトキシ−３−ヒドロキシエチルアゼチジン−２−オン誘導体の製造方法
CA1256444A (en) 1986-04-30 1989-06-27 Kazunori Kan Process for preparing 4-acetoxy-3- hydroxyethylazetidin-2-one derivatives
JPS62289558A (ja) 1986-06-09 1987-12-16 Sagami Chem Res Center β−ラクタム化合物およびその製造方法
CN1017991B (zh) 1987-02-20 1992-08-26 钟渊化学工业株式会社 4-乙酰氧基-3-羟乙基氮杂环丁-2-酮衍生物的制备方法
JPS6421698A (en) 1987-07-17 1989-01-25 Fuji Electric Co Ltd Goods replenishing port display device for vending machine
JPH01101084A (ja) 1987-10-14 1989-04-19 Mitsubishi Electric Corp 静止画像伝送装置
JPH01216965A (ja) 1988-02-25 1989-08-30 Sagami Chem Res Center ２−アルコキシブロピオン酸アミド誘導体の製造方法
JPH01246255A (ja) 1988-03-26 1989-10-02 Sagami Chem Res Center ４−アシルオキシ−β−ラクタム誘導体の製造方法
CA2000565C (en) 1988-10-19 1998-06-23 Masaji Ishiguro Process for the preparation of 4-acyloxy-2-azetidinone derivatives
JPH0733381B2 (ja) 1988-12-26 1995-04-12 財団法人相模中央化学研究所 １，３―ジオキサン誘導体
JPH02172970A (ja) 1988-12-26 1990-07-04 Sagami Chem Res Center ４―アシルオキシ―２―アゼチジノンの製造方法
JPH0276888A (ja) 1989-08-28 1990-03-16 Kanegafuchi Chem Ind Co Ltd 新規β―ラクタム化合物及びその製造法

Also Published As

Publication number Publication date
PL227494B1 (pl) 2017-12-29
WO2014097257A1 (en) 2014-06-26

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