PL405076A1 - Zastosowanie alpha-cyklodrkstryny do wytwarzania leku do obnizenia poziomów leptyny, poziomów insuliny lub opornosci na insuline - Google Patents
Zastosowanie alpha-cyklodrkstryny do wytwarzania leku do obnizenia poziomów leptyny, poziomów insuliny lub opornosci na insulineInfo
- Publication number
- PL405076A1 PL405076A1 PL405076A PL40507603A PL405076A1 PL 405076 A1 PL405076 A1 PL 405076A1 PL 405076 A PL405076 A PL 405076A PL 40507603 A PL40507603 A PL 40507603A PL 405076 A1 PL405076 A1 PL 405076A1
- Authority
- PL
- Poland
- Prior art keywords
- levels
- insulin
- cyclodextrin
- medicament
- manufacture
- Prior art date
Links
- NOESYZHRGYRDHS-UHFFFAOYSA-N insulin Chemical compound N1C(=O)C(NC(=O)C(CCC(N)=O)NC(=O)C(CCC(O)=O)NC(=O)C(C(C)C)NC(=O)C(NC(=O)CN)C(C)CC)CSSCC(C(NC(CO)C(=O)NC(CC(C)C)C(=O)NC(CC=2C=CC(O)=CC=2)C(=O)NC(CCC(N)=O)C(=O)NC(CC(C)C)C(=O)NC(CCC(O)=O)C(=O)NC(CC(N)=O)C(=O)NC(CC=2C=CC(O)=CC=2)C(=O)NC(CSSCC(NC(=O)C(C(C)C)NC(=O)C(CC(C)C)NC(=O)C(CC=2C=CC(O)=CC=2)NC(=O)C(CC(C)C)NC(=O)C(C)NC(=O)C(CCC(O)=O)NC(=O)C(C(C)C)NC(=O)C(CC(C)C)NC(=O)C(CC=2NC=NC=2)NC(=O)C(CO)NC(=O)CNC2=O)C(=O)NCC(=O)NC(CCC(O)=O)C(=O)NC(CCCNC(N)=N)C(=O)NCC(=O)NC(CC=3C=CC=CC=3)C(=O)NC(CC=3C=CC=CC=3)C(=O)NC(CC=3C=CC(O)=CC=3)C(=O)NC(C(C)O)C(=O)N3C(CCC3)C(=O)NC(CCCCN)C(=O)NC(C)C(O)=O)C(=O)NC(CC(N)=O)C(O)=O)=O)NC(=O)C(C(C)CC)NC(=O)C(CO)NC(=O)C(C(C)O)NC(=O)C1CSSCC2NC(=O)C(CC(C)C)NC(=O)C(NC(=O)C(CCC(N)=O)NC(=O)C(CC(N)=O)NC(=O)C(NC(=O)C(N)CC=1C=CC=CC=1)C(C)C)CC1=CN=CN1 NOESYZHRGYRDHS-UHFFFAOYSA-N 0.000 title abstract 6
- 102000004877 Insulin Human genes 0.000 title abstract 3
- 108090001061 Insulin Proteins 0.000 title abstract 3
- 206010022489 Insulin Resistance Diseases 0.000 title abstract 3
- 102000016267 Leptin Human genes 0.000 title abstract 3
- 108010092277 Leptin Proteins 0.000 title abstract 3
- 239000003814 drug Substances 0.000 title abstract 3
- 229940125396 insulin Drugs 0.000 title abstract 3
- NRYBAZVQPHGZNS-ZSOCWYAHSA-N leptin Chemical compound O=C([C@H](CO)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](CC=1C2=CC=CC=C2NC=1)NC(=O)[C@H](CC(C)C)NC(=O)[C@@H](NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CO)NC(=O)CNC(=O)[C@H](CCC(N)=O)NC(=O)[C@@H](N)CC(C)C)CCSC)N1CCC[C@H]1C(=O)NCC(=O)N[C@@H](CS)C(O)=O NRYBAZVQPHGZNS-ZSOCWYAHSA-N 0.000 title abstract 3
- 229940039781 leptin Drugs 0.000 title abstract 3
- 208000001072 type 2 diabetes mellitus Diseases 0.000 title abstract 3
- 238000004519 manufacturing process Methods 0.000 title abstract 2
- 229920001450 Alpha-Cyclodextrin Polymers 0.000 title 1
- HFHDHCJBZVLPGP-RWMJIURBSA-N alpha-cyclodextrin Chemical compound OC[C@H]([C@H]([C@@H]([C@H]1O)O)O[C@H]2O[C@@H]([C@@H](O[C@H]3O[C@H](CO)[C@H]([C@@H]([C@H]3O)O)O[C@H]3O[C@H](CO)[C@H]([C@@H]([C@H]3O)O)O[C@H]3O[C@H](CO)[C@H]([C@@H]([C@H]3O)O)O3)[C@H](O)[C@H]2O)CO)O[C@@H]1O[C@H]1[C@H](O)[C@@H](O)[C@@H]3O[C@@H]1CO HFHDHCJBZVLPGP-RWMJIURBSA-N 0.000 title 1
- 229940043377 alpha-cyclodextrin Drugs 0.000 title 1
- 229920000858 Cyclodextrin Polymers 0.000 abstract 2
- 239000001116 FEMA 4028 Substances 0.000 abstract 1
- WHGYBXFWUBPSRW-FOUAGVGXSA-N beta-cyclodextrin Chemical compound OC[C@H]([C@H]([C@@H]([C@H]1O)O)O[C@H]2O[C@@H]([C@@H](O[C@H]3O[C@H](CO)[C@H]([C@@H]([C@H]3O)O)O[C@H]3O[C@H](CO)[C@H]([C@@H]([C@H]3O)O)O[C@H]3O[C@H](CO)[C@H]([C@@H]([C@H]3O)O)O[C@H]3O[C@H](CO)[C@H]([C@@H]([C@H]3O)O)O3)[C@H](O)[C@H]2O)CO)O[C@@H]1O[C@H]1[C@H](O)[C@@H](O)[C@@H]3O[C@@H]1CO WHGYBXFWUBPSRW-FOUAGVGXSA-N 0.000 abstract 1
- 235000011175 beta-cyclodextrine Nutrition 0.000 abstract 1
- 229960004853 betadex Drugs 0.000 abstract 1
- 229940079593 drug Drugs 0.000 abstract 1
- HFHDHCJBZVLPGP-UHFFFAOYSA-N schardinger α-dextrin Chemical compound O1C(C(C2O)O)C(CO)OC2OC(C(C2O)O)C(CO)OC2OC(C(C2O)O)C(CO)OC2OC(C(O)C2O)C(CO)OC2OC(C(C2O)O)C(CO)OC2OC2C(O)C(O)C1OC2CO HFHDHCJBZVLPGP-UHFFFAOYSA-N 0.000 abstract 1
Classifications
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Abstract
Wynalazek dotyczy zastosowania ?-cyklodekstryny do wytwarzania leku do obnizania poziomów leptyny, poziomów insuliny lub opornosci na insuline, w którym wymagajacemu tego podmiotowi podaje sie wystarczajaca ilosc leku do obnizenia poziomów leptyny, poziomów insuliny lub opornosci na insuline, przy czym stosunek ilosci podawanej ?-cyklodekstryny i ilosci tluszczu spozywanego dziennie przez wymieniony podmiot wynosi od 1:20 do 1:3 wagowo.
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US40436602P | 2002-08-19 | 2002-08-19 | |
| US46184703P | 2003-04-11 | 2003-04-11 | |
| US48644003P | 2003-07-14 | 2003-07-14 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| PL405076A1 true PL405076A1 (pl) | 2013-12-09 |
| PL220779B1 PL220779B1 (pl) | 2016-01-29 |
Family
ID=31892100
Family Applications (6)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PL405076A PL220779B1 (pl) | 2002-08-19 | 2003-07-29 | Zastosowanie α-cyklodekstryny do wytwarzania leku do obniżania poziomów leptyny, poziomów insuliny lub oporności na insulinę |
| PL405077A PL220776B1 (pl) | 2002-08-19 | 2003-07-29 | Zastosowanie α-cyklodekstryny do wytwarzania leku do zmniejszania biegunki |
| PL396944A PL220645B1 (pl) | 2002-08-19 | 2003-07-29 | Zastosowanie α-cyklodekstryny do wytwarzania leku do ułatwiania utraty masy ciała |
| PL405074A PL220643B1 (pl) | 2002-08-19 | 2003-07-29 | Zastosowanie α-cyklodekstryny do wytwarzania leku do obniżania poziomów trójglicerydów |
| PL375374A PL213863B1 (pl) | 2002-08-19 | 2003-07-29 | Konsumpcyjny maczny produkt zywnosciowy, konsumpcyjny niemaczny produkt zywnosciowy, sposób polepszania organoleptycznych wlasciwosci zawierajacego tluszcz konsumpcyjnego produktu zywnosciowego i sposób zmniejszania dostepnosci biologicznej tluszczu w konsumpcyjnym zawierajacym tluszcz produkcie zywnosciowym |
| PL405075A PL220780B1 (pl) | 2002-08-19 | 2003-07-29 | Zastosowanie α-cyklodekstryny do wytwarzania leku do podwyższania poziomu cholesterolu lipoproteinowego o wysokiej gęstości (HDL) oraz do zmniejszania stosunku cholesterol/HDL |
Family Applications After (5)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PL405077A PL220776B1 (pl) | 2002-08-19 | 2003-07-29 | Zastosowanie α-cyklodekstryny do wytwarzania leku do zmniejszania biegunki |
| PL396944A PL220645B1 (pl) | 2002-08-19 | 2003-07-29 | Zastosowanie α-cyklodekstryny do wytwarzania leku do ułatwiania utraty masy ciała |
| PL405074A PL220643B1 (pl) | 2002-08-19 | 2003-07-29 | Zastosowanie α-cyklodekstryny do wytwarzania leku do obniżania poziomów trójglicerydów |
| PL375374A PL213863B1 (pl) | 2002-08-19 | 2003-07-29 | Konsumpcyjny maczny produkt zywnosciowy, konsumpcyjny niemaczny produkt zywnosciowy, sposób polepszania organoleptycznych wlasciwosci zawierajacego tluszcz konsumpcyjnego produktu zywnosciowego i sposób zmniejszania dostepnosci biologicznej tluszczu w konsumpcyjnym zawierajacym tluszcz produkcie zywnosciowym |
| PL405075A PL220780B1 (pl) | 2002-08-19 | 2003-07-29 | Zastosowanie α-cyklodekstryny do wytwarzania leku do podwyższania poziomu cholesterolu lipoproteinowego o wysokiej gęstości (HDL) oraz do zmniejszania stosunku cholesterol/HDL |
Country Status (22)
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| US (4) | US6890549B2 (pl) |
| EP (4) | EP1478401B1 (pl) |
| JP (3) | JP4418751B2 (pl) |
| CN (1) | CN100542609C (pl) |
| AT (1) | ATE442165T1 (pl) |
| AU (1) | AU2003259235B2 (pl) |
| BR (1) | BRPI0309572B1 (pl) |
| CA (2) | CA2480668C (pl) |
| CY (1) | CY1115026T1 (pl) |
| DE (1) | DE60329168D1 (pl) |
| DK (2) | DK2138190T3 (pl) |
| ES (1) | ES2457017T3 (pl) |
| IL (2) | IL164332A0 (pl) |
| MA (1) | MA27959A1 (pl) |
| MX (1) | MXPA04012880A (pl) |
| NO (2) | NO334081B1 (pl) |
| NZ (1) | NZ535665A (pl) |
| PL (6) | PL220779B1 (pl) |
| PT (1) | PT2138190E (pl) |
| SI (1) | SI2138190T1 (pl) |
| WO (1) | WO2004016101A2 (pl) |
| ZA (1) | ZA200407806B (pl) |
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| EP1447013A1 (en) * | 2003-02-14 | 2004-08-18 | Wacker-Chemie GmbH | Method for reducing the glycemic index of food |
| US7105195B2 (en) * | 2003-07-25 | 2006-09-12 | General Mills, Inc. | Reduced trans fat product |
| US7335386B2 (en) | 2003-07-30 | 2008-02-26 | Gerneral Mills, Inc. | Method for preventing acrylamide formation in food products and food intermediates |
| US20040180125A1 (en) * | 2003-03-11 | 2004-09-16 | Plank David W. | Cyclodextrin-containing compositions and methods |
| CA2547934C (en) * | 2004-02-19 | 2013-05-21 | Abbott Laboratories | Methods of using gamma cyclodextrin to control blood glucose and insulin secretion |
| US7780873B2 (en) * | 2004-02-23 | 2010-08-24 | Texas A&M University System | Bioactive complexes compositions and methods of use thereof |
| US7736684B2 (en) * | 2004-06-22 | 2010-06-15 | General Mills, Inc. | Viscous fat compositions having low amounts of trans-fat, methods and products |
| US20070003681A1 (en) * | 2005-06-30 | 2007-01-04 | Kraft Foods Holdings, Inc. | Stable aerated food products containing oil and cyclodextrin |
| AU2006335082B2 (en) * | 2005-12-22 | 2011-09-29 | General Mills, Inc. | Method of making complexed fat compositions |
| WO2007073543A2 (en) * | 2005-12-22 | 2007-06-28 | General Mills, Inc. | Method of preferentially reducing absorption of saturated fat and compositions |
| JP2008031055A (ja) * | 2006-06-29 | 2008-02-14 | Shunkosha:Kk | 酢酸を含有してなる摂取用組成物 |
| US20090023682A1 (en) * | 2007-07-19 | 2009-01-22 | Joseph Artiss | Composition Comprising Dietary Fat Complexer and Methods of Using Same |
| US20100112122A1 (en) * | 2008-04-30 | 2010-05-06 | Yun-Jeong Hong | Method of preferentially reducing absorbability of saturated fatty acids |
| MY183041A (en) | 2008-05-13 | 2021-02-08 | Astrazeneca Ab | Fumarate salt of 4- (3-chloro-2-fluoroanilino) -7-methoxy-6- {[1- (n-methylcarbamoylmethyl) piperidin- 4-yl] oxy}quinazoline |
| AU2011228758A1 (en) | 2010-03-13 | 2012-11-08 | Eastpond Laboratories Limited | Fat-binding compositions |
| EP2568827B1 (en) * | 2010-05-14 | 2018-04-25 | Omega Pharma Innovation & Development NV | Composition for reducing absorption of dietary fat |
| US10052345B2 (en) | 2010-10-19 | 2018-08-21 | University Of Miami | Assays, methods and kits for predicting renal disease and personalized treatment strategies |
| CA2822995C (en) | 2010-12-31 | 2021-05-11 | Eastpond Laboratories Limited | Cellular hydration compositions containing cyclodextrins |
| US20120171184A1 (en) | 2010-12-31 | 2012-07-05 | Lajos Szente | Cellular hydration compositions |
| CN111419870A (zh) * | 2012-04-13 | 2020-07-17 | L&F研究有限公司 | 使用环糊精的方法 |
| US9636048B2 (en) | 2013-03-14 | 2017-05-02 | Group Mee Llc | Specialized sensors and techniques for monitoring personal activity |
| JP6735964B2 (ja) * | 2016-04-28 | 2020-08-05 | 株式会社ハートテック | 血糖値上昇抑制の加工食品 |
| EP3687549A4 (en) | 2017-09-28 | 2021-07-14 | Asdera LLC | USE OF CYCLODEXTRIN IN DISEASES AND DISORDERS WITH PHOSPHOLIPID FAILURE REGULATION |
| JP7120068B2 (ja) * | 2018-02-28 | 2022-08-17 | トヨタ紡織株式会社 | 動物の育成方法及び育成装置 |
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| CN115105524A (zh) * | 2021-03-18 | 2022-09-27 | 南京壹盛康品生物科技有限公司 | α-环糊精在制备改善和保护胰岛功能方面的功能食品或保健品及药物中的应用 |
| CN116349747A (zh) * | 2021-12-28 | 2023-06-30 | 南京盛德生物科技研究院有限公司 | 一种能自发泡的健康液体脂肪组合物及其制备方法与应用 |
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- 2003-07-29 EP EP12196390.4A patent/EP2641615A3/en not_active Withdrawn
- 2003-07-29 PL PL405077A patent/PL220776B1/pl unknown
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- 2003-07-29 PL PL396944A patent/PL220645B1/pl unknown
- 2003-07-29 WO PCT/US2003/023291 patent/WO2004016101A2/en not_active Ceased
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