PL4229056T3 - Związki triazolopirydynylu jako inhibitory kinaz - Google Patents
Związki triazolopirydynylu jako inhibitory kinazInfo
- Publication number
- PL4229056T3 PL4229056T3 PL21805787.5T PL21805787T PL4229056T3 PL 4229056 T3 PL4229056 T3 PL 4229056T3 PL 21805787 T PL21805787 T PL 21805787T PL 4229056 T3 PL4229056 T3 PL 4229056T3
- Authority
- PL
- Poland
- Prior art keywords
- triazolopyridinyl
- compounds
- kinase inhibitors
- kinase
- inhibitors
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/4353—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems
- A61K31/437—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems the heterocyclic ring system containing a five-membered ring having nitrogen as a ring hetero atom, e.g. indolizine, beta-carboline
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/06—Antipsoriatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Medicinal Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Neurosurgery (AREA)
- Neurology (AREA)
- Hospice & Palliative Care (AREA)
- Biomedical Technology (AREA)
- Cardiology (AREA)
- Rheumatology (AREA)
- Psychiatry (AREA)
- Heart & Thoracic Surgery (AREA)
- Dermatology (AREA)
- Pain & Pain Management (AREA)
- Immunology (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Physical Education & Sports Medicine (AREA)
- Epidemiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US202063093463P | 2020-10-19 | 2020-10-19 | |
| PCT/US2021/055340 WO2022086828A1 (en) | 2020-10-19 | 2021-10-18 | Triazolopyridinyl compounds as kinase inhibitors |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| PL4229056T3 true PL4229056T3 (pl) | 2024-06-10 |
Family
ID=78536657
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PL21805787.5T PL4229056T3 (pl) | 2020-10-19 | 2021-10-18 | Związki triazolopirydynylu jako inhibitory kinaz |
Country Status (26)
| Country | Link |
|---|---|
| US (3) | US11767322B2 (pl) |
| EP (2) | EP4229056B1 (pl) |
| JP (1) | JP7730897B2 (pl) |
| KR (1) | KR20230092960A (pl) |
| CN (1) | CN116802181B (pl) |
| AR (1) | AR123793A1 (pl) |
| AU (1) | AU2021364302A1 (pl) |
| CA (1) | CA3196059A1 (pl) |
| CL (1) | CL2023001123A1 (pl) |
| CO (1) | CO2023004926A2 (pl) |
| DK (1) | DK4229056T3 (pl) |
| ES (1) | ES2987662T3 (pl) |
| FI (1) | FI4229056T3 (pl) |
| HR (1) | HRP20240739T1 (pl) |
| HU (1) | HUE067776T2 (pl) |
| IL (1) | IL302113A (pl) |
| LT (1) | LT4229056T (pl) |
| MX (1) | MX2023004492A (pl) |
| PE (1) | PE20240219A1 (pl) |
| PL (1) | PL4229056T3 (pl) |
| PT (1) | PT4229056T (pl) |
| RS (1) | RS65620B1 (pl) |
| SI (1) | SI4229056T1 (pl) |
| SM (1) | SMT202400242T1 (pl) |
| TW (1) | TW202233614A (pl) |
| WO (1) | WO2022086828A1 (pl) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| LT3580220T (lt) * | 2017-02-13 | 2021-12-27 | Bristol-Myers Squibb Company | Aminotriazolopiridinai, kaip kinazės inhibitoriai |
| US12275721B2 (en) | 2019-10-03 | 2025-04-15 | Bristol-Myers Squibb Company | Indazole carboxamides as kinase inhibitors |
| AR123793A1 (es) * | 2020-10-19 | 2023-01-11 | Bristol Myers Squibb Co | Compuestos de triazolopiridinilo como inhibidores de quinasas |
| WO2025072392A1 (en) | 2023-09-27 | 2025-04-03 | Bristol-Myers Squibb Company | Triazolopyridinyl ether linked compounds as kinase inhibitors |
Family Cites Families (27)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2005077948A1 (ja) | 2004-02-16 | 2005-08-25 | Daiichi Pharmaceutical Co., Ltd. | 抗真菌作用複素環化合物 |
| JP2008504294A (ja) | 2004-06-25 | 2008-02-14 | アムジエン・インコーポレーテツド | サイトカイン介在疾患および他の疾患の治療において有用な縮合トリアゾールおよびインダゾール |
| ES2320955B1 (es) | 2007-03-02 | 2010-03-16 | Laboratorios Almirall S.A. | Nuevos derivados de 3-((1,2,4)triazolo(4,3-a)piridin-7-il)benzamida. |
| US20110105457A1 (en) | 2008-04-18 | 2011-05-05 | Shionogi & Co., Ltd. | Heterocyclic compound having inhibitory activity on pi3k |
| WO2010007100A1 (en) | 2008-07-15 | 2010-01-21 | Cellzome Ltd | 7-substituted amino triazoles as pi3k inhibitors |
| WO2010007099A1 (en) | 2008-07-15 | 2010-01-21 | Cellzome Limited | 2-aminoimidazo[1,2-b]pyridazine derivatives as pi3k inhibitors |
| WO2010057877A1 (en) | 2008-11-18 | 2010-05-27 | Cellzome Limited | 7-pyridinyl- or phenyl- substituted triazolo [1, 5 -a] pyridines as pi3k inhibitors |
| US8598163B2 (en) | 2009-02-04 | 2013-12-03 | Vitae Pharmaceuticals, Inc. | Derivatives of [1,3]Oxazin-2-one useful for the treatment of metabolic diseases such as lipid disorders |
| US9783573B2 (en) | 2012-09-18 | 2017-10-10 | Bristol-Myers Squibb Company | IAP antagonists |
| PE20160747A1 (es) | 2013-06-10 | 2016-08-25 | Bayer Pharma AG | Derivados heterociclicos inhibidores de la quinasa mps-1 |
| RU2017109122A (ru) | 2014-08-21 | 2018-09-21 | Глэксосмитклайн Интеллекчуал Проперти Дивелопмент Лимитед | Способы лечения с использованием гетероциклических амидов в качестве ингибиторов киназы |
| WO2016064958A1 (en) | 2014-10-22 | 2016-04-28 | Bristol-Myers Squibb Company | Heteroaryl substituted pyrrolotriazine amine compounds as pi3k inhibitors |
| EP3209664B1 (en) | 2014-10-22 | 2020-06-03 | Bristol-Myers Squibb Company | Bicyclic heteroaryl amine compounds as pi3k inhibitors |
| JP6763396B2 (ja) | 2015-11-05 | 2020-09-30 | 住友化学株式会社 | 縮合複素環化合物 |
| WO2018017435A1 (en) | 2016-07-22 | 2018-01-25 | Accro Bioscience Inc. | Heteroaryl compounds as inhibitors of necrosis, composition and application thereof |
| CN110198942B (zh) | 2017-01-24 | 2022-04-15 | 住友化学株式会社 | 稠合杂环化合物及含有其的组合物 |
| LT3580220T (lt) * | 2017-02-13 | 2021-12-27 | Bristol-Myers Squibb Company | Aminotriazolopiridinai, kaip kinazės inhibitoriai |
| WO2018237370A1 (en) | 2017-06-23 | 2018-12-27 | Accro Bioscience Inc. | Heteroaryl compounds as inhibitors of necrosis, composition and method using the same |
| CN111566103B (zh) * | 2017-10-30 | 2023-06-23 | 百时美施贵宝公司 | 作为激酶抑制剂的氨基咪唑并吡嗪 |
| US11618753B2 (en) | 2018-01-26 | 2023-04-04 | Bristol-Myers Squibb Company | Aminopyrrolotriazines as kinase inhibitors |
| KR102906523B1 (ko) | 2018-09-13 | 2025-12-30 | 브리스톨-마이어스 스큅 컴퍼니 | 수용체-상호작용 단백질 키나제 1 (ripk1) 억제제로서의 1h-인다졸 카르복스아미드 |
| KR102793119B1 (ko) | 2018-09-13 | 2025-04-07 | 브리스톨-마이어스 스큅 컴퍼니 | 키나제 억제제로서의 인다졸 카르복스아미드 |
| US12509455B2 (en) | 2018-11-07 | 2025-12-30 | Dana-Farber Cancer Institute, Inc. | Imidazopyridine derivatives and aza-imidazopyridine derivatives as Janus kinase 2 inhibitors and uses thereof |
| CA3131337C (en) | 2019-03-22 | 2023-10-17 | Genfleet Therapeutics (Shanghai) Inc. | Substituted heterocyclic amide compound and preparation method therefor and pharmaceutical use thereof |
| US12275721B2 (en) | 2019-10-03 | 2025-04-15 | Bristol-Myers Squibb Company | Indazole carboxamides as kinase inhibitors |
| CN114230565B (zh) | 2020-09-09 | 2023-10-27 | 成都奥睿药业有限公司 | 5-取代吲哚3-酰胺衍生物及其制备方法和用途 |
| AR123793A1 (es) * | 2020-10-19 | 2023-01-11 | Bristol Myers Squibb Co | Compuestos de triazolopiridinilo como inhibidores de quinasas |
-
2021
- 2021-10-14 AR ARP210102843A patent/AR123793A1/es not_active Application Discontinuation
- 2021-10-18 TW TW110138596A patent/TW202233614A/zh unknown
- 2021-10-18 LT LTEPPCT/US2021/055340T patent/LT4229056T/lt unknown
- 2021-10-18 SM SM20240242T patent/SMT202400242T1/it unknown
- 2021-10-18 EP EP21805787.5A patent/EP4229056B1/en active Active
- 2021-10-18 FI FIEP21805787.5T patent/FI4229056T3/fi active
- 2021-10-18 PL PL21805787.5T patent/PL4229056T3/pl unknown
- 2021-10-18 WO PCT/US2021/055340 patent/WO2022086828A1/en not_active Ceased
- 2021-10-18 PT PT218057875T patent/PT4229056T/pt unknown
- 2021-10-18 IL IL302113A patent/IL302113A/en unknown
- 2021-10-18 EP EP24159615.4A patent/EP4364737A3/en active Pending
- 2021-10-18 JP JP2023523570A patent/JP7730897B2/ja active Active
- 2021-10-18 ES ES21805787T patent/ES2987662T3/es active Active
- 2021-10-18 MX MX2023004492A patent/MX2023004492A/es unknown
- 2021-10-18 PE PE2023001446A patent/PE20240219A1/es unknown
- 2021-10-18 HR HRP20240739TT patent/HRP20240739T1/hr unknown
- 2021-10-18 US US17/503,516 patent/US11767322B2/en active Active
- 2021-10-18 AU AU2021364302A patent/AU2021364302A1/en not_active Abandoned
- 2021-10-18 CN CN202180070933.6A patent/CN116802181B/zh active Active
- 2021-10-18 KR KR1020237016535A patent/KR20230092960A/ko active Pending
- 2021-10-18 SI SI202130138T patent/SI4229056T1/sl unknown
- 2021-10-18 HU HUE21805787A patent/HUE067776T2/hu unknown
- 2021-10-18 RS RS20240656A patent/RS65620B1/sr unknown
- 2021-10-18 DK DK21805787.5T patent/DK4229056T3/da active
- 2021-10-18 CA CA3196059A patent/CA3196059A1/en active Pending
-
2023
- 2023-04-18 CL CL2023001123A patent/CL2023001123A1/es unknown
- 2023-04-19 CO CONC2023/0004926A patent/CO2023004926A2/es unknown
- 2023-07-06 US US18/347,703 patent/US12110290B2/en active Active
-
2024
- 2024-08-28 US US18/817,352 patent/US20240425505A1/en active Pending
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