PL4229056T3 - Związki triazolopirydynylu jako inhibitory kinaz - Google Patents
Związki triazolopirydynylu jako inhibitory kinazInfo
- Publication number
- PL4229056T3 PL4229056T3 PL21805787.5T PL21805787T PL4229056T3 PL 4229056 T3 PL4229056 T3 PL 4229056T3 PL 21805787 T PL21805787 T PL 21805787T PL 4229056 T3 PL4229056 T3 PL 4229056T3
- Authority
- PL
- Poland
- Prior art keywords
- triazolopyridinyl
- compounds
- kinase inhibitors
- kinase
- inhibitors
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/4353—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems
- A61K31/437—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems the heterocyclic ring system containing a five-membered ring having nitrogen as a ring hetero atom, e.g. indolizine, beta-carboline
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/06—Antipsoriatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Medicinal Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Neurosurgery (AREA)
- Neurology (AREA)
- Hospice & Palliative Care (AREA)
- Biomedical Technology (AREA)
- Cardiology (AREA)
- Rheumatology (AREA)
- Psychiatry (AREA)
- Heart & Thoracic Surgery (AREA)
- Dermatology (AREA)
- Pain & Pain Management (AREA)
- Immunology (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Physical Education & Sports Medicine (AREA)
- Epidemiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US202063093463P | 2020-10-19 | 2020-10-19 | |
| PCT/US2021/055340 WO2022086828A1 (en) | 2020-10-19 | 2021-10-18 | Triazolopyridinyl compounds as kinase inhibitors |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| PL4229056T3 true PL4229056T3 (pl) | 2024-06-10 |
Family
ID=78536657
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PL21805787.5T PL4229056T3 (pl) | 2020-10-19 | 2021-10-18 | Związki triazolopirydynylu jako inhibitory kinaz |
Country Status (26)
| Country | Link |
|---|---|
| US (3) | US11767322B2 (pl) |
| EP (2) | EP4364737A3 (pl) |
| JP (1) | JP7730897B2 (pl) |
| KR (1) | KR20230092960A (pl) |
| CN (1) | CN116802181A (pl) |
| AR (1) | AR123793A1 (pl) |
| AU (1) | AU2021364302A1 (pl) |
| CA (1) | CA3196059A1 (pl) |
| CL (1) | CL2023001123A1 (pl) |
| CO (1) | CO2023004926A2 (pl) |
| DK (1) | DK4229056T3 (pl) |
| ES (1) | ES2987662T3 (pl) |
| FI (1) | FI4229056T3 (pl) |
| HR (1) | HRP20240739T1 (pl) |
| HU (1) | HUE067776T2 (pl) |
| IL (1) | IL302113A (pl) |
| LT (1) | LT4229056T (pl) |
| MX (1) | MX2023004492A (pl) |
| PE (1) | PE20240219A1 (pl) |
| PL (1) | PL4229056T3 (pl) |
| PT (1) | PT4229056T (pl) |
| RS (1) | RS65620B1 (pl) |
| SI (1) | SI4229056T1 (pl) |
| SM (1) | SMT202400242T1 (pl) |
| TW (1) | TW202233614A (pl) |
| WO (1) | WO2022086828A1 (pl) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP3580220B1 (en) * | 2017-02-13 | 2021-11-17 | Bristol-Myers Squibb Company | Aminotriazolopyridines as kinase inhibitors |
| WO2021067654A1 (en) | 2019-10-03 | 2021-04-08 | Bristol-Myers Squibb Company | Indazole carboxamides as kinase inhibitors |
| AR123793A1 (es) * | 2020-10-19 | 2023-01-11 | Bristol Myers Squibb Co | Compuestos de triazolopiridinilo como inhibidores de quinasas |
| CN121969620A (zh) | 2023-09-27 | 2026-05-01 | 百时美施贵宝公司 | 作为激酶抑制剂的三唑并吡啶醚连接的化合物 |
Family Cites Families (27)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP1717238A4 (en) | 2004-02-16 | 2008-03-05 | Daiichi Seiyaku Co | FUNGICIDES HETEROCYCLIC COMPOUNDS |
| AU2005260031B2 (en) | 2004-06-25 | 2008-10-09 | Amgen Inc. | Condensed triazoles and indazoles useful in treating citokines mediated diseases and other diseases |
| ES2320955B1 (es) | 2007-03-02 | 2010-03-16 | Laboratorios Almirall S.A. | Nuevos derivados de 3-((1,2,4)triazolo(4,3-a)piridin-7-il)benzamida. |
| EP2277881A4 (en) | 2008-04-18 | 2011-09-07 | Shionogi & Co | HETEROCYCLIC COMPOUND HAVING INHIBITORY ACTIVITY ON P13K |
| WO2010007100A1 (en) | 2008-07-15 | 2010-01-21 | Cellzome Ltd | 7-substituted amino triazoles as pi3k inhibitors |
| WO2010007099A1 (en) | 2008-07-15 | 2010-01-21 | Cellzome Limited | 2-aminoimidazo[1,2-b]pyridazine derivatives as pi3k inhibitors |
| WO2010057877A1 (en) | 2008-11-18 | 2010-05-27 | Cellzome Limited | 7-pyridinyl- or phenyl- substituted triazolo [1, 5 -a] pyridines as pi3k inhibitors |
| CA2750517A1 (en) | 2009-02-04 | 2010-08-12 | Vitae Pharmaceuticals, Inc. | Cyclic inhibitors of 11beta-hydroxysteroid dehydrogenase 1 |
| US9783573B2 (en) | 2012-09-18 | 2017-10-10 | Bristol-Myers Squibb Company | IAP antagonists |
| HK1219737A1 (zh) | 2013-06-10 | 2017-04-13 | Bayer Pharma Aktiengesellschaft | 用於治疗癌症的新化合物 |
| CN106573006A (zh) | 2014-08-21 | 2017-04-19 | 葛兰素史密斯克莱知识产权发展有限公司 | 作为药物的rip1激酶抑制剂杂环酰胺 |
| EP3209665B1 (en) | 2014-10-22 | 2019-08-14 | Bristol-Myers Squibb Company | Substituted pyrrolotriazine amine compounds as pi3k inhibitors |
| ES2807785T3 (es) | 2014-10-22 | 2021-02-24 | Bristol Myers Squibb Co | Compuestos de heteroarilamina bicíclicos como inhibidores de pi3k |
| US10709133B2 (en) | 2015-11-05 | 2020-07-14 | Sumitomo Chemical Company, Limited | Condensed heterocyclic compound |
| WO2018017435A1 (en) | 2016-07-22 | 2018-01-25 | Accro Bioscience Inc. | Heteroaryl compounds as inhibitors of necrosis, composition and application thereof |
| JP7190906B2 (ja) | 2017-01-24 | 2022-12-16 | 住友化学株式会社 | 縮合複素環化合物及びそれを含有する組成物 |
| EP3580220B1 (en) * | 2017-02-13 | 2021-11-17 | Bristol-Myers Squibb Company | Aminotriazolopyridines as kinase inhibitors |
| WO2018237370A1 (en) | 2017-06-23 | 2018-12-27 | Accro Bioscience Inc. | Heteroaryl compounds as inhibitors of necrosis, composition and method using the same |
| DK3704118T3 (da) * | 2017-10-30 | 2022-03-14 | Bristol Myers Squibb Co | Aminoimidazopyrazin som kinasehæmmere |
| SG11202007035YA (en) | 2018-01-26 | 2020-08-28 | Bristol Myers Squibb Co | Aminopyrrolotriazines as kinase inhibitors |
| EP3849969B1 (en) | 2018-09-13 | 2023-04-19 | Bristol-Myers Squibb Company | Indazole carboxamides as kinase inhibitors |
| EP3849968B1 (en) | 2018-09-13 | 2022-12-21 | Bristol-Myers Squibb Company | 1h-indazole carboxamides as receptor-interacting protein kinase 1 inhibitors (ripk1) |
| EP3877371A4 (en) | 2018-11-07 | 2022-07-27 | Dana-Farber Cancer Institute, Inc. | IMIDAZOPYRIDINE DERIVATIVES AND AZA-IMIDAZOPYRIDINE DERIVATIVES AS JANUS KINASE 2 INHIBITORS AND USES THEREOF |
| US20220177462A1 (en) | 2019-03-22 | 2022-06-09 | Genfleet Therapeutics (Shanghai) Inc. | Substituted heterocyclic amide compound and preparation method therefor and pharmaceutical use thereof |
| WO2021067654A1 (en) | 2019-10-03 | 2021-04-08 | Bristol-Myers Squibb Company | Indazole carboxamides as kinase inhibitors |
| CN114230565B (zh) | 2020-09-09 | 2023-10-27 | 成都奥睿药业有限公司 | 5-取代吲哚3-酰胺衍生物及其制备方法和用途 |
| AR123793A1 (es) * | 2020-10-19 | 2023-01-11 | Bristol Myers Squibb Co | Compuestos de triazolopiridinilo como inhibidores de quinasas |
-
2021
- 2021-10-14 AR ARP210102843A patent/AR123793A1/es not_active Application Discontinuation
- 2021-10-18 PE PE2023001446A patent/PE20240219A1/es unknown
- 2021-10-18 US US17/503,516 patent/US11767322B2/en active Active
- 2021-10-18 IL IL302113A patent/IL302113A/en unknown
- 2021-10-18 AU AU2021364302A patent/AU2021364302A1/en not_active Abandoned
- 2021-10-18 KR KR1020237016535A patent/KR20230092960A/ko active Pending
- 2021-10-18 ES ES21805787T patent/ES2987662T3/es active Active
- 2021-10-18 EP EP24159615.4A patent/EP4364737A3/en active Pending
- 2021-10-18 SI SI202130138T patent/SI4229056T1/sl unknown
- 2021-10-18 TW TW110138596A patent/TW202233614A/zh unknown
- 2021-10-18 MX MX2023004492A patent/MX2023004492A/es unknown
- 2021-10-18 RS RS20240656A patent/RS65620B1/sr unknown
- 2021-10-18 HU HUE21805787A patent/HUE067776T2/hu unknown
- 2021-10-18 PL PL21805787.5T patent/PL4229056T3/pl unknown
- 2021-10-18 LT LTEPPCT/US2021/055340T patent/LT4229056T/lt unknown
- 2021-10-18 JP JP2023523570A patent/JP7730897B2/ja active Active
- 2021-10-18 DK DK21805787.5T patent/DK4229056T3/da active
- 2021-10-18 PT PT218057875T patent/PT4229056T/pt unknown
- 2021-10-18 FI FIEP21805787.5T patent/FI4229056T3/fi active
- 2021-10-18 CN CN202180070933.6A patent/CN116802181A/zh active Pending
- 2021-10-18 SM SM20240242T patent/SMT202400242T1/it unknown
- 2021-10-18 HR HRP20240739TT patent/HRP20240739T1/hr unknown
- 2021-10-18 EP EP21805787.5A patent/EP4229056B1/en active Active
- 2021-10-18 CA CA3196059A patent/CA3196059A1/en active Pending
- 2021-10-18 WO PCT/US2021/055340 patent/WO2022086828A1/en not_active Ceased
-
2023
- 2023-04-18 CL CL2023001123A patent/CL2023001123A1/es unknown
- 2023-04-19 CO CONC2023/0004926A patent/CO2023004926A2/es unknown
- 2023-07-06 US US18/347,703 patent/US12110290B2/en active Active
-
2024
- 2024-08-28 US US18/817,352 patent/US20240425505A1/en active Pending
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