PL426424A1 - 1-Palmitoyl-2-cinnamoyl-sn-glycerol-3-phosphocholine and method of preparing 1-palmitoyl-2-cinnamoyl-sn-glycerol-3-phosphocholine - Google Patents

1-Palmitoyl-2-cinnamoyl-sn-glycerol-3-phosphocholine and method of preparing 1-palmitoyl-2-cinnamoyl-sn-glycerol-3-phosphocholine

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Publication number
PL426424A1
PL426424A1 PL426424A PL42642418A PL426424A1 PL 426424 A1 PL426424 A1 PL 426424A1 PL 426424 A PL426424 A PL 426424A PL 42642418 A PL42642418 A PL 42642418A PL 426424 A1 PL426424 A1 PL 426424A1
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PL
Poland
Prior art keywords
phosphocholine
palmitoyl
cinnamoyl
glycerol
formula
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Application number
PL426424A
Other languages
Polish (pl)
Other versions
PL235464B1 (en
Inventor
Anna Gliszczyńska
Marta Czarnecka
Original Assignee
Uniwersytet Przyrodniczy we Wrocławiu
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Application filed by Uniwersytet Przyrodniczy we Wrocławiu filed Critical Uniwersytet Przyrodniczy we Wrocławiu
Priority to PL426424A priority Critical patent/PL235464B1/en
Publication of PL426424A1 publication Critical patent/PL426424A1/en
Publication of PL235464B1 publication Critical patent/PL235464B1/en

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  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Cosmetics (AREA)

Abstract

Zgłoszenie dotyczy fosfolipidowej pochodnej o wzorze 3 kwasu cynamonowego, o wzorze 1 oraz sposobu jej otrzymywania na drodze estryfikacji z 1-palmitoilo-2-hydroksy-sn-glicero-3-fosfocholiną o wzorze 2 z udziałem czynnika sprzęgającego jakim jest N,N'-dicykloheksylokarbodiimid oraz w obecności 4-(N,N-dimetyloamino)pirydyny w środowisku bezwodnego chlorku metylenu albo chloroformu. Przedstawione rozwiązanie może znaleźć zastosowanie w przemyśle farmaceutycznym lub kosmetycznym.The application relates to a phospholipid derivative of formula 3 of cinnamic acid, formula 1 and a method of its preparation by esterification with 1-palmitoyl-2-hydroxy-sn-glycero-3-phosphocholine of formula 2 with the use of a coupling agent which is N, N'- dicyclohexylcarbodiimide and in the presence of 4- (N, N-dimethylamino) pyridine in anhydrous methylene chloride or chloroform. The presented solution can be used in the pharmaceutical or cosmetic industry.

PL426424A 2018-07-24 2018-07-24 1-Palmitoyl-2-cinnamoyl-sn-glycerol-3-phosphocholine and method of preparing 1-palmitoyl-2-cinnamoyl-sn-glycerol-3-phosphocholine PL235464B1 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
PL426424A PL235464B1 (en) 2018-07-24 2018-07-24 1-Palmitoyl-2-cinnamoyl-sn-glycerol-3-phosphocholine and method of preparing 1-palmitoyl-2-cinnamoyl-sn-glycerol-3-phosphocholine

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
PL426424A PL235464B1 (en) 2018-07-24 2018-07-24 1-Palmitoyl-2-cinnamoyl-sn-glycerol-3-phosphocholine and method of preparing 1-palmitoyl-2-cinnamoyl-sn-glycerol-3-phosphocholine

Publications (2)

Publication Number Publication Date
PL426424A1 true PL426424A1 (en) 2020-01-27
PL235464B1 PL235464B1 (en) 2020-08-10

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PL426424A PL235464B1 (en) 2018-07-24 2018-07-24 1-Palmitoyl-2-cinnamoyl-sn-glycerol-3-phosphocholine and method of preparing 1-palmitoyl-2-cinnamoyl-sn-glycerol-3-phosphocholine

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PL (1) PL235464B1 (en)

Also Published As

Publication number Publication date
PL235464B1 (en) 2020-08-10

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