PL4301748T3 - Triazolilo-metylo podstawione pochodne alfa-d-galaktopiranozydu - Google Patents
Triazolilo-metylo podstawione pochodne alfa-d-galaktopiranozyduInfo
- Publication number
- PL4301748T3 PL4301748T3 PL22708569.3T PL22708569T PL4301748T3 PL 4301748 T3 PL4301748 T3 PL 4301748T3 PL 22708569 T PL22708569 T PL 22708569T PL 4301748 T3 PL4301748 T3 PL 4301748T3
- Authority
- PL
- Poland
- Prior art keywords
- triazolyl
- methyl substituted
- substituted alpha
- galactopyranoside
- derivatives
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H7/00—Compounds containing non-saccharide radicals linked to saccharide radicals by a carbon-to-carbon bond
- C07H7/06—Heterocyclic radicals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/4192—1,2,3-Triazoles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/12—Drugs for disorders of the urinary system of the kidneys
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/04—Immunostimulants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/14—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing three or more hetero rings
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Immunology (AREA)
- Heart & Thoracic Surgery (AREA)
- Cardiology (AREA)
- Urology & Nephrology (AREA)
- Pain & Pain Management (AREA)
- Rheumatology (AREA)
- Ophthalmology & Optometry (AREA)
- Biochemistry (AREA)
- Epidemiology (AREA)
- Biotechnology (AREA)
- Genetics & Genomics (AREA)
- Molecular Biology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Saccharide Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP2021055348 | 2021-03-03 | ||
| PCT/EP2022/055224 WO2022184755A1 (en) | 2021-03-03 | 2022-03-02 | Triazolyl-methyl substituted alpha-d-galactopyranoside derivatives |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| PL4301748T3 true PL4301748T3 (pl) | 2025-09-08 |
Family
ID=80682779
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PL22708569.3T PL4301748T3 (pl) | 2021-03-03 | 2022-03-02 | Triazolilo-metylo podstawione pochodne alfa-d-galaktopiranozydu |
Country Status (20)
| Country | Link |
|---|---|
| US (1) | US20240109930A1 (pl) |
| EP (1) | EP4301748B1 (pl) |
| JP (1) | JP7771205B2 (pl) |
| KR (1) | KR20230154221A (pl) |
| CN (1) | CN116888113A (pl) |
| AU (1) | AU2022228660A1 (pl) |
| BR (1) | BR112023017624A2 (pl) |
| CA (1) | CA3209917A1 (pl) |
| CL (1) | CL2023002578A1 (pl) |
| ES (1) | ES3033422T3 (pl) |
| HR (1) | HRP20250833T1 (pl) |
| HU (1) | HUE072194T2 (pl) |
| IL (1) | IL305581A (pl) |
| MA (1) | MA63589B1 (pl) |
| MX (1) | MX2023010241A (pl) |
| PL (1) | PL4301748T3 (pl) |
| RS (1) | RS67032B1 (pl) |
| TW (1) | TWI905393B (pl) |
| UA (1) | UA130562C2 (pl) |
| WO (1) | WO2022184755A1 (pl) |
Families Citing this family (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP4010348B1 (en) | 2019-08-09 | 2023-12-20 | Idorsia Pharmaceuticals Ltd | (2-acetamidyl)thio-beta-d-galactopyranoside derivatives |
| WO2021028336A1 (en) | 2019-08-09 | 2021-02-18 | Idorsia Pharmaceuticals Ltd | (hetero)aryl-methyl-thio-beta-d-galactopyranoside derivatives |
| US12291519B2 (en) | 2019-08-15 | 2025-05-06 | Idorsia Pharmaceuticals Ltd | 2-hydroxycycloalkane-1-carbamoyl |
| CA3148365A1 (en) | 2019-08-29 | 2021-03-04 | Martin Bolli | Alpha-d-galactopyranoside derivatives |
| CA3194831A1 (en) | 2020-10-06 | 2022-04-14 | Martin Bolli | Spiro derivatives of alpha-d-galactopyranosides |
| US12291520B2 (en) | 2020-11-02 | 2025-05-06 | Idorsia Pharmaceuticals Ltd | Galectin-3 inhibiting 2-hydroxycycloalkane-1-carbamoyl derivatives |
| JP2024506182A (ja) | 2021-02-09 | 2024-02-09 | イドーシア ファーマシューティカルズ リミテッド | ヒドロキシヘテロシクロアルカン－カルバモイル誘導体 |
Family Cites Families (21)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| SE0100172D0 (sv) | 2001-01-22 | 2001-01-22 | Ulf Nilsson | New inhibitors against galectins |
| SE0401301D0 (sv) | 2004-05-21 | 2004-05-21 | Forskarpatent I Syd Ab | Novel 3-triazolyl-galactoside inhibitors of galectins |
| SE0401300D0 (sv) | 2004-05-21 | 2004-05-21 | Forskarpatent I Syd Ab | Novel Galactoside Inhibitors of Galectins |
| WO2014059135A1 (en) | 2012-10-10 | 2014-04-17 | Galectin Therapeutics, Inc. | Galactose-pronged carbohydrate compounds for the treatment of diabetic nephropathy and associated disorders |
| CA2884802A1 (en) | 2012-10-31 | 2014-05-08 | Galecto Biotech Ab | Galactoside inhibitor of galectin-3 and its use for treating pulmonary fibrosis |
| CA2926480A1 (en) | 2012-11-15 | 2014-05-22 | Tufts University | Methods, compositions and kits for treating, modulating, or preventing ocular angiogenesis or fibrosis in a subject using a galectin protein inhibitor |
| EP3250581B1 (en) | 2015-01-30 | 2021-01-20 | Galecto Biotech AB | Alpha-d-galactoside inhibitors of galectins |
| WO2017007689A1 (en) | 2015-07-06 | 2017-01-12 | Gilead Sciences, Inc. | Cot modulators and methods of use thereof |
| JP7204676B2 (ja) | 2017-05-12 | 2023-01-16 | ガレクティン・サイエンシーズ・リミテッド・ライアビリティ・カンパニー | 疾患の予防および治療用の化合物およびその使用 |
| MX2019013536A (es) | 2017-05-12 | 2020-02-13 | Galectin Sciences Llc | Compuestos para el tratamiento de los trastornos de resistencia sistemica a la insulina y el uso de los mismos. |
| WO2019067702A1 (en) | 2017-09-27 | 2019-04-04 | Bristol-Myers Squibb Company | INHIBITORS WITH SMALL MOLECULES OF GALECTIN-3 |
| WO2019075045A1 (en) | 2017-10-11 | 2019-04-18 | Bristol-Myers Squibb Company | INHIBITORS WITH SMALL MOLECULES OF GALECTIN-3 |
| KR20200081443A (ko) | 2017-10-31 | 2020-07-07 | 갈랙틴 사이언시즈, 엘엘씨 | 전신성 인슐린 저항성 질환의 치료를 위한 셀레노갈락토사이드 화합물 및 이의 용도 |
| WO2020104335A1 (en) | 2018-11-21 | 2020-05-28 | Galecto Biotech Ab | Alpha-d-galactoside inhibitors of galectins |
| KR102890853B1 (ko) * | 2019-04-10 | 2025-11-24 | 브리스톨-마이어스 스큅 컴퍼니 | 갈렉틴-3의 소분자 억제제 |
| US12441754B2 (en) | 2019-07-03 | 2025-10-14 | Galecto Biotech Ab | Galactoside inhibitor of galectins |
| EP3994135A1 (en) | 2019-07-05 | 2022-05-11 | Galecto Biotech AB | Novel galactoside inhibitor of galectins |
| EP4010348B1 (en) | 2019-08-09 | 2023-12-20 | Idorsia Pharmaceuticals Ltd | (2-acetamidyl)thio-beta-d-galactopyranoside derivatives |
| WO2021028336A1 (en) | 2019-08-09 | 2021-02-18 | Idorsia Pharmaceuticals Ltd | (hetero)aryl-methyl-thio-beta-d-galactopyranoside derivatives |
| US12291519B2 (en) | 2019-08-15 | 2025-05-06 | Idorsia Pharmaceuticals Ltd | 2-hydroxycycloalkane-1-carbamoyl |
| CA3148365A1 (en) | 2019-08-29 | 2021-03-04 | Martin Bolli | Alpha-d-galactopyranoside derivatives |
-
2022
- 2022-03-02 MA MA63589A patent/MA63589B1/fr unknown
- 2022-03-02 UA UAA202304634A patent/UA130562C2/uk unknown
- 2022-03-02 TW TW111107565A patent/TWI905393B/zh active
- 2022-03-02 MX MX2023010241A patent/MX2023010241A/es unknown
- 2022-03-02 RS RS20250732A patent/RS67032B1/sr unknown
- 2022-03-02 BR BR112023017624A patent/BR112023017624A2/pt unknown
- 2022-03-02 ES ES22708569T patent/ES3033422T3/es active Active
- 2022-03-02 AU AU2022228660A patent/AU2022228660A1/en active Pending
- 2022-03-02 CN CN202280017484.3A patent/CN116888113A/zh active Pending
- 2022-03-02 US US18/548,833 patent/US20240109930A1/en active Pending
- 2022-03-02 JP JP2023552539A patent/JP7771205B2/ja active Active
- 2022-03-02 KR KR1020237033375A patent/KR20230154221A/ko active Pending
- 2022-03-02 EP EP22708569.3A patent/EP4301748B1/en active Active
- 2022-03-02 HU HUE22708569A patent/HUE072194T2/hu unknown
- 2022-03-02 HR HRP20250833TT patent/HRP20250833T1/hr unknown
- 2022-03-02 CA CA3209917A patent/CA3209917A1/en active Pending
- 2022-03-02 PL PL22708569.3T patent/PL4301748T3/pl unknown
- 2022-03-02 IL IL305581A patent/IL305581A/en unknown
- 2022-03-02 WO PCT/EP2022/055224 patent/WO2022184755A1/en not_active Ceased
-
2023
- 2023-08-31 CL CL2023002578A patent/CL2023002578A1/es unknown
Also Published As
| Publication number | Publication date |
|---|---|
| MA63589B1 (fr) | 2025-07-31 |
| MX2023010241A (es) | 2023-09-12 |
| IL305581A (en) | 2023-10-01 |
| EP4301748C0 (en) | 2025-05-07 |
| JP7771205B2 (ja) | 2025-11-17 |
| TWI905393B (zh) | 2025-11-21 |
| US20240109930A1 (en) | 2024-04-04 |
| AU2022228660A1 (en) | 2023-10-19 |
| EP4301748B1 (en) | 2025-05-07 |
| UA130562C2 (uk) | 2026-03-18 |
| HUE072194T2 (hu) | 2025-10-28 |
| EP4301748A1 (en) | 2024-01-10 |
| HRP20250833T1 (hr) | 2025-09-12 |
| ES3033422T3 (en) | 2025-08-04 |
| BR112023017624A2 (pt) | 2023-10-10 |
| CN116888113A (zh) | 2023-10-13 |
| TW202300146A (zh) | 2023-01-01 |
| CA3209917A1 (en) | 2022-09-09 |
| CL2023002578A1 (es) | 2024-03-22 |
| RS67032B1 (sr) | 2025-08-29 |
| JP2024509421A (ja) | 2024-03-01 |
| WO2022184755A1 (en) | 2022-09-09 |
| KR20230154221A (ko) | 2023-11-07 |
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