|
US7135584B2
(en)
|
1995-08-07 |
2006-11-14 |
Wake Forest University |
Lipid analogs for treating viral infections
|
|
AU3216695A
(en)
|
1994-08-29 |
1996-03-22 |
University Of North Carolina At Chapel Hill, The |
Lipid analogs for treating viral infections
|
|
NZ335276A
(en)
|
1996-10-18 |
2000-09-29 |
Vertex Pharma |
Inhibitors of serine proteases, particularly hepatitis C virus (HCV) NS3 (Non Structural Protein 3) protease
|
|
GB9806815D0
(en)
*
|
1998-03-30 |
1998-05-27 |
Hoffmann La Roche |
Amino acid derivatives
|
|
AU3376699A
(en)
*
|
1998-03-31 |
1999-10-18 |
Vertex Pharmaceuticals Incorporated |
Inhibitors of serine proteases, particularly hepatitis c virus ns3 protease
|
|
GB9809664D0
(en)
*
|
1998-05-06 |
1998-07-01 |
Hoffmann La Roche |
a-Ketoamide derivatives
|
|
US6608027B1
(en)
|
1999-04-06 |
2003-08-19 |
Boehringer Ingelheim (Canada) Ltd |
Macrocyclic peptides active against the hepatitis C virus
|
|
UA74546C2
(en)
*
|
1999-04-06 |
2006-01-16 |
Boehringer Ingelheim Ca Ltd |
Macrocyclic peptides having activity relative to hepatitis c virus, a pharmaceutical composition and use of the pharmaceutical composition
|
|
CA2376961A1
(en)
*
|
1999-07-26 |
2001-02-01 |
Bristol-Myers Squibb Pharma Company |
Lactam inhibitors of hepatitis c virus ns3 protease
|
|
US7122627B2
(en)
|
1999-07-26 |
2006-10-17 |
Bristol-Myers Squibb Company |
Lactam inhibitors of Hepatitis C virus NS3 protease
|
|
US7026469B2
(en)
|
2000-10-19 |
2006-04-11 |
Wake Forest University School Of Medicine |
Compositions and methods of double-targeting virus infections and cancer cells
|
|
DE60036881T2
(de)
*
|
1999-11-24 |
2008-07-10 |
Novartis Vaccines and Diagnostics, Inc., Emeryville |
Neues nichtstrukturelles hcv-polypeptid
|
|
US6986892B1
(en)
|
1999-11-24 |
2006-01-17 |
Chiron Corporation |
Immunogenic Hepatitis C virus non-structural polypeptides
|
|
AU2055301A
(en)
|
1999-12-03 |
2001-06-12 |
Bristol-Myers Squibb Pharma Company |
Alpha-ketoamide inhibitors of hepatitis c virus ns3 protease
|
|
US6613507B1
(en)
|
2000-03-21 |
2003-09-02 |
Yu-an Chang |
Boraadamantane compounds for the treatment of pathogenic viruses and other medical applications
|
|
HK1047947A1
(zh)
*
|
2000-04-05 |
2003-03-14 |
Schering Corporation |
包含n-环状p2部分的丙型肝炎病毒的大环ns3-丝氨酸蛋白酶抑制剂
|
|
AU2001253621A1
(en)
*
|
2000-04-19 |
2001-11-07 |
Schering Corporation |
Macrocyclic NS3-serine protease inhibitors of hepatitis C virus comprising alkyl and aryl alanine P2 moieties
|
|
MY164523A
(en)
|
2000-05-23 |
2017-12-29 |
Univ Degli Studi Cagliari |
Methods and compositions for treating hepatitis c virus
|
|
PL359169A1
(en)
|
2000-05-26 |
2004-08-23 |
Idenix (Cayman) Limited |
Methods and compositions for treating flaviviruses and pestiviruses
|
|
US7012066B2
(en)
|
2000-07-21 |
2006-03-14 |
Schering Corporation |
Peptides as NS3-serine protease inhibitors of hepatitis C virus
|
|
US7244721B2
(en)
|
2000-07-21 |
2007-07-17 |
Schering Corporation |
Peptides as NS3-serine protease inhibitors of hepatitis C virus
|
|
AR029851A1
(es)
|
2000-07-21 |
2003-07-16 |
Dendreon Corp |
Nuevos peptidos como inhibidores de ns3-serina proteasa del virus de hepatitis c
|
|
SK742003A3
(en)
|
2000-07-21 |
2003-06-03 |
Schering Corp |
Novel peptides as NS3-serine protease inhibitors of hepatitis C virus
|
|
SV2003000617A
(es)
|
2000-08-31 |
2003-01-13 |
Lilly Co Eli |
Inhibidores de la proteasa peptidomimetica ref. x-14912m
|
|
KR20090089922A
(ko)
|
2000-10-18 |
2009-08-24 |
파마셋 인코포레이티드 |
바이러스 감염 및 비정상적인 세포 증식의 치료를 위한 변형된 뉴클레오시드
|
|
US7309696B2
(en)
|
2000-10-19 |
2007-12-18 |
Wake Forest University |
Compositions and methods for targeting cancer cells
|
|
US6846806B2
(en)
|
2000-10-23 |
2005-01-25 |
Bristol-Myers Squibb Company |
Peptide inhibitors of Hepatitis C virus NS3 protein
|
|
MXPA03006514A
(es)
|
2001-01-22 |
2004-12-02 |
Merck & Co Inc |
Derivados de nucleosidos como inhibidores de polimerasa de acido ribonucleico viral dependiente de acido ribonucleico.
|
|
KR100926244B1
(ko)
|
2001-07-11 |
2009-11-12 |
버텍스 파마슈티칼스 인코포레이티드 |
브릿지된 바이사이클릭 세린 프로테아제 억제제
|
|
MXPA04001917A
(es)
|
2001-08-31 |
2004-06-15 |
Thomson Licensing Sa |
Contador de secuencia para una corriente audio-visual.
|
|
AU2002330154A1
(en)
|
2001-09-28 |
2003-04-07 |
Centre National De La Recherche Scientifique |
Methods and compositions for treating hepatitis c virus using 4'-modified nucleosides
|
|
MXPA04003825A
(es)
|
2001-10-24 |
2004-07-08 |
Vertex Pharma |
Inhibidores de serina proteasa, en particular la ns3-ns4a proteasa del virus de hepatitis c, que incorpora un sistema de anillo fusionado.
|
|
WO2003037893A1
(en)
*
|
2001-11-02 |
2003-05-08 |
Glaxo Group Limited |
Acyl dihydro pyrrole derivatives as hcv inhibitors
|
|
US20030176689A1
(en)
*
|
2001-12-14 |
2003-09-18 |
Michael Joyce |
Inhibitors of hepatitis C virus protease
|
|
MXPA04007163A
(es)
|
2002-01-23 |
2004-10-29 |
Schering Corp |
Compuestos de prolina como inhibidores de la proteasa serina ns3 para utilizarse en el tratamiento de la infeccion por el virus de la hepatitis c.
|
|
US7119072B2
(en)
|
2002-01-30 |
2006-10-10 |
Boehringer Ingelheim (Canada) Ltd. |
Macrocyclic peptides active against the hepatitis C virus
|
|
US7091184B2
(en)
|
2002-02-01 |
2006-08-15 |
Boehringer Ingelheim International Gmbh |
Hepatitis C inhibitor tri-peptides
|
|
US6642204B2
(en)
|
2002-02-01 |
2003-11-04 |
Boehringer Ingelheim International Gmbh |
Hepatitis C inhibitor tri-peptides
|
|
EP1497282A2
(en)
|
2002-04-11 |
2005-01-19 |
Vertex Pharmaceuticals Incorporated |
Inhibitors of serine protease, particularly hepatitis c virus ns3-ns4 protease
|
|
MY140680A
(en)
|
2002-05-20 |
2010-01-15 |
Bristol Myers Squibb Co |
Hepatitis c virus inhibitors
|
|
PL215228B1
(pl)
|
2002-05-20 |
2013-11-29 |
Bristol Myers Squibb Co |
Zwiazki tripeptydowe, ich zastosowanie i kompozycja farmaceutyczna je zawierajaca oraz jej zastosowanie
|
|
AU2003248535A1
(en)
|
2002-05-20 |
2003-12-12 |
Bristol-Myers Squibb Company |
Heterocyclicsulfonamide hepatitis c virus inhibitors
|
|
ES2315568T3
(es)
|
2002-05-20 |
2009-04-01 |
Bristol-Myers Squibb Company |
Inhibidores del virus de la hepatitis c basados en cicloalquilo p1' sustituido.
|
|
AU2003247084B9
(en)
|
2002-06-28 |
2018-07-26 |
Centre National De La Recherche Scientifique |
Modified 2' and 3'-nucleoside prodrugs for treating flaviridae infections
|
|
US20050075279A1
(en)
|
2002-10-25 |
2005-04-07 |
Boehringer Ingelheim International Gmbh |
Macrocyclic peptides active against the hepatitis C virus
|
|
AU2003298658A1
(en)
|
2002-11-15 |
2004-06-15 |
Idenix (Cayman) Limited |
2'-branched nucleosides and flaviviridae mutation
|
|
CL2004001161A1
(es)
*
|
2003-05-21 |
2005-04-08 |
Boehringer Ingelheim Int |
Compuestos describe compuestos derivados de quinolina; composicion farmaceutica; y su uso para tratar una enfermedad causada por el virus de la hepatitis c.
|
|
RU2358979C2
(ru)
|
2003-05-30 |
2009-06-20 |
Фармассет, Инк. |
Модифицированные фторированные аналоги нуклеозида
|
|
ATE478886T1
(de)
|
2003-07-25 |
2010-09-15 |
Idenix Pharmaceuticals Inc |
Purin nucleoside für die behandlung von durch flavividrae verursachten krankheiten, einschliesslich hepatitis c
|
|
MXPA06002250A
(es)
|
2003-08-26 |
2006-05-17 |
Schering Corp |
Inhibidores peptidomimeticos novedosos de la serina proteasa ns3 del virus de la hepatitis c.
|
|
MY148123A
(en)
|
2003-09-05 |
2013-02-28 |
Vertex Pharma |
Inhibitors of serine proteases, particularly hcv ns3-ns4a protease
|
|
EP1673385B1
(en)
|
2003-09-22 |
2011-03-02 |
Boehringer Ingelheim International GmbH |
Macrocyclic peptides active against the hepatitis c virus
|
|
CN1894274A
(zh)
|
2003-09-26 |
2007-01-10 |
先灵公司 |
丙肝病毒ns3丝氨酸蛋白酶的大环抑制剂
|
|
NZ546663A
(en)
|
2003-10-10 |
2010-01-29 |
Vertex Pharma |
Inhibitors of serine proteases, particularly HCV NS3-NS4A protease
|
|
WO2005037214A2
(en)
|
2003-10-14 |
2005-04-28 |
Intermune, Inc. |
Macrocyclic carboxylic acids and acylsulfonamides as inhibitors of hcv replication
|
|
EP1944042A1
(en)
|
2003-10-27 |
2008-07-16 |
Vertex Pharmceuticals Incorporated |
Combinations for HCV treatment
|
|
ES2389201T3
(es)
|
2003-10-27 |
2012-10-24 |
Vertex Pharmaceuticals Incorporated |
Mutantes de resistencia de la proteasa NS3/4A de HCV
|
|
WO2005043118A2
(en)
|
2003-10-27 |
2005-05-12 |
Vertex Pharmaceuticals Incorporated |
Drug discovery method
|
|
US7132504B2
(en)
|
2003-11-12 |
2006-11-07 |
Bristol-Myers Squibb Company |
Hepatitis C virus inhibitors
|
|
US7135462B2
(en)
|
2003-11-20 |
2006-11-14 |
Bristol-Myers Squibb Company |
Hepatitis C virus inhibitors
|
|
US7309708B2
(en)
|
2003-11-20 |
2007-12-18 |
Birstol-Myers Squibb Company |
Hepatitis C virus inhibitors
|
|
MXPA06005683A
(es)
|
2003-11-20 |
2006-12-14 |
Schering Corp |
Inhibidores despeptidizados de la proteasa ns3 del virus de la hepatitis c.
|
|
GB0500020D0
(en)
|
2005-01-04 |
2005-02-09 |
Novartis Ag |
Organic compounds
|
|
WO2005070955A1
(en)
|
2004-01-21 |
2005-08-04 |
Boehringer Ingelheim International Gmbh |
Macrocyclic peptides active against the hepatitis c virus
|
|
ES2336009T3
(es)
|
2004-01-30 |
2010-04-07 |
Medivir Ab |
Inhibidores de la ns-3 serina proteasa del vhc.
|
|
EP1711515A2
(en)
|
2004-02-04 |
2006-10-18 |
Vertex Pharmaceuticals Incorporated |
Inhibitors of serine proteases, particularly hcv ns3-ns4a protease
|
|
US20050182252A1
(en)
|
2004-02-13 |
2005-08-18 |
Reddy K. R. |
Novel 2'-C-methyl nucleoside derivatives
|
|
CN1922174A
(zh)
|
2004-02-20 |
2007-02-28 |
贝林格尔·英格海姆国际有限公司 |
病毒聚合酶抑制剂
|
|
US20070049593A1
(en)
|
2004-02-24 |
2007-03-01 |
Japan Tobacco Inc. |
Tetracyclic fused heterocyclic compound and use thereof as HCV polymerase inhibitor
|
|
WO2005080399A1
(ja)
|
2004-02-24 |
2005-09-01 |
Japan Tobacco Inc. |
4環縮合複素環化合物及びそのhcvポリメラーゼ阻害剤としての利用
|
|
RU2006134005A
(ru)
|
2004-02-27 |
2008-04-10 |
Шеринг Корпорейшн (US) |
Новые соединения, действующие как ингибиторы сериновой протеазы ns3 вируса гепатита с
|
|
CN1950393A
(zh)
|
2004-02-27 |
2007-04-18 |
先灵公司 |
丙型肝炎病毒ns3蛋白酶的抑制剂
|
|
ATE438622T1
(de)
|
2004-02-27 |
2009-08-15 |
Schering Corp |
3,4-(cyclopentyl)kondensierte prolinverbindungen als inhibitoren der ns3-serinprotease des hepatitis-c-virus
|
|
US7816326B2
(en)
|
2004-02-27 |
2010-10-19 |
Schering Corporation |
Sulfur compounds as inhibitors of hepatitis C virus NS3 serine protease
|
|
RU2428428C9
(ru)
|
2004-02-27 |
2012-03-10 |
Шеринг Корпорейшн |
Серусодержащие соединения, действующие как ингибиторы сериновой протеазы ns3 вируса гепатита с
|
|
RU2006134002A
(ru)
|
2004-02-27 |
2008-04-10 |
Шеринг Корпорейшн (US) |
Новые соединения, действующие как ингибиторы сериновой протеазы ns3 вируса гепатита с
|
|
CN1984922A
(zh)
|
2004-05-20 |
2007-06-20 |
先灵公司 |
用作丙型肝炎病毒ns3丝氨酸蛋白酶抑制剂的取代脯氨酸
|
|
WO2005123087A2
(en)
|
2004-06-15 |
2005-12-29 |
Merck & Co., Inc. |
C-purine nucleoside analogs as inhibitors of rna-dependent rna viral polymerase
|
|
US20070265222A1
(en)
|
2004-06-24 |
2007-11-15 |
Maccoss Malcolm |
Nucleoside Aryl Phosphoramidates for the Treatment of Rna-Dependent Rna Viral Infection
|
|
UY29016A1
(es)
*
|
2004-07-20 |
2006-02-24 |
Boehringer Ingelheim Int |
Analogos de dipeptidos inhibidores de la hepatitis c
|
|
JP4914355B2
(ja)
|
2004-07-20 |
2012-04-11 |
ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング |
C型肝炎インヒビターペプチド類似体
|
|
CN101023094B
(zh)
|
2004-07-21 |
2011-05-18 |
法莫赛特股份有限公司 |
烷基取代的2-脱氧-2-氟代-d-呋喃核糖基嘧啶和嘌呤及其衍生物的制备
|
|
US7597884B2
(en)
|
2004-08-09 |
2009-10-06 |
Alios Biopharma, Inc. |
Hyperglycosylated polypeptide variants and methods of use
|
|
MX2007002371A
(es)
|
2004-08-27 |
2007-04-23 |
Schering Corp |
Compuestos de acilsulfonamida como inhibidores de la serina proteasa ns3 del virus de la hepatitis c.
|
|
ES2725457T3
(es)
|
2004-09-14 |
2019-09-24 |
Gilead Pharmasset Llc |
Preparación de ribofuranosil pirimidinas y purinas 2'fluoro-2'-alquil-sustituidas u otras opcionalmente sustituidas y sus derivados
|
|
US20080267915A1
(en)
|
2004-10-01 |
2008-10-30 |
Vertex Pharmaceuticals |
Hcv Ns3-Ns4a Protease Inhibition
|
|
US7659263B2
(en)
|
2004-11-12 |
2010-02-09 |
Japan Tobacco Inc. |
Thienopyrrole compound and use thereof as HCV polymerase inhibitor
|
|
US7323447B2
(en)
|
2005-02-08 |
2008-01-29 |
Bristol-Myers Squibb Company |
Hepatitis C virus inhibitors
|
|
AU2006242475B2
(en)
|
2005-05-02 |
2011-07-07 |
Merck Sharp & Dohme Corp. |
HCV NS3 protease inhibitors
|
|
US7592336B2
(en)
|
2005-05-10 |
2009-09-22 |
Bristol-Myers Squibb Company |
Hepatitis C virus inhibitors
|
|
JP5030947B2
(ja)
|
2005-05-13 |
2012-09-19 |
ヴァイロケム・ファーマ・インコーポレーテッド |
フラビウイルス感染の治療及び予防のための化合物及び方法
|
|
US8119602B2
(en)
|
2005-06-02 |
2012-02-21 |
Schering Corporation |
Administration of HCV protease inhibitors in combination with food to improve bioavailability
|
|
US7772178B2
(en)
*
|
2005-06-02 |
2010-08-10 |
Schering Corporation |
Pharmaceutical formulations and methods of treatment using the same
|
|
US20070237818A1
(en)
*
|
2005-06-02 |
2007-10-11 |
Malcolm Bruce A |
Controlled-release formulation of HCV protease inhibitor and methods using the same
|
|
RU2427372C2
(ru)
|
2005-06-17 |
2011-08-27 |
Новартис Аг |
Применение санглиферина для лечения вируса гепатита с
|
|
US7601686B2
(en)
|
2005-07-11 |
2009-10-13 |
Bristol-Myers Squibb Company |
Hepatitis C virus inhibitors
|
|
AR057456A1
(es)
|
2005-07-20 |
2007-12-05 |
Merck & Co Inc |
Inhibidores de la proteasa ns3 del vhc
|
|
EP2305696A3
(en)
|
2005-07-25 |
2011-10-12 |
Intermune, Inc. |
Macrocyclic inhibitors of Hepatitis C virus replication
|
|
PE20070210A1
(es)
|
2005-07-29 |
2007-04-16 |
Tibotec Pharm Ltd |
Compuestos macrociclicos como inhibidores del virus de hepatitis c
|
|
RU2436787C2
(ru)
|
2005-07-29 |
2011-12-20 |
Тиботек Фармасьютикалз Лтд. |
Макроциклические ингибиторы вируса гепатита с
|
|
BRPI0614637A2
(pt)
|
2005-07-29 |
2011-04-12 |
Tibotec Pharm Ltd |
inibidores macrocìclicos do vìrus da hepatite c
|
|
JO2768B1
(en)
|
2005-07-29 |
2014-03-15 |
تيبوتيك فارماسيوتيكالز ليمتد |
Large cyclic inhibitors of hepatitis C virus
|
|
WO2007014922A1
(en)
|
2005-07-29 |
2007-02-08 |
Tibotec Pharmaceuticals Ltd. |
Macrocyclic inhibitors of hepatitis c virus
|
|
AR055105A1
(es)
|
2005-07-29 |
2007-08-08 |
Tibotec Pharm Ltd |
Inhibidores macrociclicos del virus de la hepatitis c
|
|
EP1919904B1
(en)
|
2005-07-29 |
2014-01-08 |
Janssen R&D Ireland |
Macrocyclic inhibitors of hepatitis c virus
|
|
PE20070211A1
(es)
|
2005-07-29 |
2007-05-12 |
Medivir Ab |
Compuestos macrociclicos como inhibidores del virus de hepatitis c
|
|
ATE496042T1
(de)
|
2005-07-29 |
2011-02-15 |
Tibotec Pharm Ltd |
Makrocyclische inhibitoren des hepatitis-c-virus
|
|
US8278322B2
(en)
|
2005-08-01 |
2012-10-02 |
Merck Sharp & Dohme Corp. |
HCV NS3 protease inhibitors
|
|
ES2401661T3
(es)
*
|
2005-08-02 |
2013-04-23 |
Vertex Pharmaceuticals Incorporated |
Inhibidores de serina proteasas
|
|
CA2618560A1
(en)
|
2005-08-09 |
2007-02-22 |
Merck & Co., Inc. |
Ribonucleoside cyclic acetal derivatives for the treatment of rna-dependent rna viral infection
|
|
CA2618682C
(en)
|
2005-08-12 |
2011-06-21 |
Boehringer Ingelheim International Gmbh |
Viral polymerase inhibitors
|
|
RU2446171C2
(ru)
*
|
2005-08-19 |
2012-03-27 |
Вертекс Фармасьютикалз Инкорпорейтед |
Способы и промежуточные продукты
|
|
US8399615B2
(en)
|
2005-08-19 |
2013-03-19 |
Vertex Pharmaceuticals Incorporated |
Processes and intermediates
|
|
AR055395A1
(es)
|
2005-08-26 |
2007-08-22 |
Vertex Pharma |
Compuestos inhibidores de la actividad de la serina proteasa ns3-ns4a del virus de la hepatitis c
|
|
US7964624B1
(en)
|
2005-08-26 |
2011-06-21 |
Vertex Pharmaceuticals Incorporated |
Inhibitors of serine proteases
|
|
EA200801050A1
(ru)
|
2005-10-11 |
2008-12-30 |
Интермьюн, Инк. |
Соединения и способы ингибирования репликации вирусного гепатита с
|
|
US7772183B2
(en)
|
2005-10-12 |
2010-08-10 |
Bristol-Myers Squibb Company |
Hepatitis C virus inhibitors
|
|
US7741281B2
(en)
|
2005-11-03 |
2010-06-22 |
Bristol-Myers Squibb Company |
Hepatitis C virus inhibitors
|
|
US7705138B2
(en)
|
2005-11-11 |
2010-04-27 |
Vertex Pharmaceuticals Incorporated |
Hepatitis C virus variants
|
|
NZ568324A
(en)
|
2005-11-11 |
2012-01-12 |
Vertex Pharma |
Hepatitis C virus variants
|
|
US7816348B2
(en)
|
2006-02-03 |
2010-10-19 |
Boehringer Ingelheim International Gmbh |
Viral polymerase inhibitors
|
|
MX2008010355A
(es)
*
|
2006-02-09 |
2008-10-31 |
Schering Corp |
Combinaciones que comprenden inhibidores de proteasa del virus de la hepatitis c e inhibidores de polimerasa del virus de la hepatitis c, y metodos de tratamiento relacionados con los mismos.
|
|
EP1991229A2
(en)
|
2006-02-27 |
2008-11-19 |
Vertex Pharmaceuticals Incorporated |
Co-crystals and pharmaceutical compositions comprising the same
|
|
JP2009531315A
(ja)
*
|
2006-03-16 |
2009-09-03 |
バーテックス ファーマシューティカルズ インコーポレイテッド |
重水素化c型肝炎プロテアーゼインヒビター
|
|
MX2008012225A
(es)
*
|
2006-03-23 |
2008-12-03 |
Schering Corp |
Combinaciones de inhibidores de proteasa de virus de hepatitis c e inhibidores de isoenzima 3a4 del citocromo p450, y metodos de tratamiento relacionados con las mismas.
|
|
EP2518079A3
(en)
|
2006-04-11 |
2012-12-12 |
Novartis AG |
HCV/HIV inhibitors and their uses
|
|
US8017612B2
(en)
|
2006-04-18 |
2011-09-13 |
Japan Tobacco Inc. |
Piperazine compound and use thereof as a HCV polymerase inhibitor
|
|
GB0609492D0
(en)
|
2006-05-15 |
2006-06-21 |
Angeletti P Ist Richerche Bio |
Therapeutic agents
|
|
EP2027143A2
(en)
|
2006-05-23 |
2009-02-25 |
Irm Llc |
Compounds and compositions as channel activating protease inhibitors
|
|
GB0612423D0
(en)
|
2006-06-23 |
2006-08-02 |
Angeletti P Ist Richerche Bio |
Therapeutic agents
|
|
WO2008008776A2
(en)
|
2006-07-11 |
2008-01-17 |
Bristol-Myers Squibb Company |
Hepatitis c virus inhibitors
|
|
EP1886685A1
(en)
|
2006-08-11 |
2008-02-13 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
Methods, uses and compositions for modulating replication of hcv through the farnesoid x receptor (fxr) activation or inhibition
|
|
WO2008019477A1
(en)
|
2006-08-17 |
2008-02-21 |
Boehringer Ingelheim International Gmbh |
Viral polymerase inhibitors
|
|
CA2667165A1
(en)
|
2006-10-24 |
2008-05-02 |
Merck & Co., Inc. |
Hcv ns3 protease inhibitors
|
|
CN101583372A
(zh)
|
2006-10-24 |
2009-11-18 |
默克公司 |
Hcv ns3蛋白酶抑制剂
|
|
US8138164B2
(en)
|
2006-10-24 |
2012-03-20 |
Merck Sharp & Dohme Corp. |
HCV NS3 protease inhibitors
|
|
JP5268927B2
(ja)
|
2006-10-27 |
2013-08-21 |
メルク・シャープ・アンド・ドーム・コーポレーション |
Hcvns3プロテアーゼ阻害剤
|
|
WO2008057208A2
(en)
|
2006-10-27 |
2008-05-15 |
Merck & Co., Inc. |
Hcv ns3 protease inhibitors
|
|
US8343477B2
(en)
|
2006-11-01 |
2013-01-01 |
Bristol-Myers Squibb Company |
Inhibitors of hepatitis C virus
|
|
US7772180B2
(en)
|
2006-11-09 |
2010-08-10 |
Bristol-Myers Squibb Company |
Hepatitis C virus inhibitors
|
|
SG176488A1
(en)
|
2006-11-15 |
2011-12-29 |
Virochem Pharma Inc |
Thiophene analogues for the treatment or prevention of flavivirus infections
|
|
US7763584B2
(en)
|
2006-11-16 |
2010-07-27 |
Bristol-Myers Squibb Company |
Hepatitis C virus inhibitors
|
|
US8003604B2
(en)
|
2006-11-16 |
2011-08-23 |
Bristol-Myers Squibb Company |
Hepatitis C virus inhibitors
|
|
US7888464B2
(en)
|
2006-11-16 |
2011-02-15 |
Bristol-Myers Squibb Company |
Hepatitis C virus inhibitors
|
|
US20100081672A1
(en)
*
|
2006-12-07 |
2010-04-01 |
Schering Corporation |
Ph sensitive matrix formulation
|
|
US8101595B2
(en)
|
2006-12-20 |
2012-01-24 |
Istituto di Ricerche di Biologia Molecolare P. Angletti SpA |
Antiviral indoles
|
|
GB0625349D0
(en)
|
2006-12-20 |
2007-01-31 |
Angeletti P Ist Richerche Bio |
Therapeutic compounds
|
|
GB0625345D0
(en)
|
2006-12-20 |
2007-01-31 |
Angeletti P Ist Richerche Bio |
Therapeutic compounds
|
|
JP5055377B2
(ja)
|
2006-12-22 |
2012-10-24 |
シェーリング コーポレイション |
[5,6−環]環形成インドール誘導体およびその使用方法
|
|
JP5079818B2
(ja)
|
2006-12-22 |
2012-11-21 |
メルク・シャープ・アンド・ドーム・コーポレーション |
Hcvおよび関連するウイルス疾患の治療または予防のための4,5−環インドール誘導体
|
|
KR20090106539A
(ko)
|
2006-12-22 |
2009-10-09 |
쉐링 코포레이션 |
Hcv 및 관련 바이러스 감염을 치료 또는 예방하기 위한 4,5-환 환상 인돌 유도체
|
|
RU2481340C2
(ru)
|
2007-02-08 |
2013-05-10 |
Тиботек Фармасьютикалз Лтд. |
Пиримидин-замещенные макроциклические ингибиторы hcv
|
|
CA2677487A1
(en)
|
2007-02-09 |
2008-08-14 |
Irm Llc |
Compounds and compositions as channel activating protease inhibitors
|
|
EA200970806A1
(ru)
|
2007-02-27 |
2010-08-30 |
Вертекс Фармасьютикалз Инкорпорейтед |
Сокристаллы и содержащие их фармацевтические композиции
|
|
US8575208B2
(en)
|
2007-02-27 |
2013-11-05 |
Vertex Pharmaceuticals Incorporated |
Inhibitors of serine proteases
|
|
WO2008106166A2
(en)
|
2007-02-28 |
2008-09-04 |
Conatus Pharmaceuticals, Inc. |
Methods for the treatment of liver diseases using specified matrix metalloproteinase (mmp) inhibitors
|
|
EP2139911A2
(en)
*
|
2007-03-23 |
2010-01-06 |
Schering Corporation |
Hydrazido-peptides as inhibitors of hcv ns3-protease
|
|
US7964580B2
(en)
|
2007-03-30 |
2011-06-21 |
Pharmasset, Inc. |
Nucleoside phosphoramidate prodrugs
|
|
MX2009011930A
(es)
|
2007-05-04 |
2009-11-18 |
Vertex Pharma |
Terapia de combinacion para el tratamiento de infeccion de virus de hepatitis c.
|
|
NZ582096A
(en)
|
2007-06-29 |
2012-05-25 |
Gilead Sciences Inc |
Antiviral compounds that inhibit hepatitis c virus (hcv)
|
|
AR068794A1
(es)
|
2007-06-29 |
2009-12-09 |
Gilead Sciences Inc |
Compuestos antivirales
|
|
AU2008277442A1
(en)
|
2007-07-17 |
2009-01-22 |
Istituto Di Ricerche Di Biologia Molecolare P. Angeletti Spa |
Macrocyclic indole derivatives for the treatment of hepatitis C infections
|
|
CN101754974B
(zh)
|
2007-07-19 |
2016-02-03 |
Msd意大利有限公司 |
作为抗病毒剂的大环化合物
|
|
WO2009018657A1
(en)
|
2007-08-03 |
2009-02-12 |
Boehringer Ingelheim International Gmbh |
Viral polymerase inhibitors
|
|
RU2010111550A
(ru)
|
2007-08-29 |
2011-10-10 |
Шеринг Корпорейшн (US) |
2,3-замещенные индольные производные для лечения вирусных инфекций
|
|
EP2195317B1
(en)
|
2007-08-29 |
2012-01-18 |
Schering Corporation |
2,3-substituted azaindole derivatives for treating viral infections
|
|
WO2009032124A1
(en)
|
2007-08-29 |
2009-03-12 |
Schering Corporation |
Substituted indole derivatives and methods of use thereof
|
|
EP2436682A1
(en)
|
2007-08-30 |
2012-04-04 |
Vertex Pharmceuticals Incorporated |
Co-crystals and pharmaceutical compositions comprising the same
|
|
GB0718575D0
(en)
|
2007-09-24 |
2007-10-31 |
Angeletti P Ist Richerche Bio |
Nucleoside derivatives as inhibitors of viral polymerases
|
|
US8765757B2
(en)
|
2007-11-16 |
2014-07-01 |
Merck Sharp & Dohme Corp. |
3-heterocyclic substituted indole derivatives and methods of use thereof
|
|
CN102317285A
(zh)
|
2007-11-16 |
2012-01-11 |
先灵公司 |
3-氨基磺酰基取代的吲哚衍生物及其使用方法
|
|
CA2708150A1
(en)
|
2007-12-05 |
2009-06-18 |
Enanta Pharmaceuticals, Inc. |
Fluorinated tripeptide hcv serine protease inhibitors
|
|
EP2234977A4
(en)
|
2007-12-19 |
2011-04-13 |
Boehringer Ingelheim Int |
VIRAL POLYMERASE INHIBITORS
|
|
US8202996B2
(en)
|
2007-12-21 |
2012-06-19 |
Bristol-Myers Squibb Company |
Crystalline forms of N-(tert-butoxycarbonyl)-3-methyl-L-valyl-(4R)-4-((7-chloro-4-methoxy-1-isoquinolinyl)oxy)-N- ((1R,2S)-1-((cyclopropylsulfonyl)carbamoyl)-2-vinylcyclopropyl)-L-prolinamide
|
|
RU2490272C2
(ru)
|
2008-02-04 |
2013-08-20 |
Айденикс Фармасьютикалз, Инк. |
Макроциклические ингибиторы серинпротеазы
|
|
TW200946541A
(en)
|
2008-03-27 |
2009-11-16 |
Idenix Pharmaceuticals Inc |
Solid forms of an anti-HIV phosphoindole compound
|
|
US8163921B2
(en)
|
2008-04-16 |
2012-04-24 |
Bristol-Myers Squibb Company |
Hepatitis C virus inhibitors
|
|
CN102014911A
(zh)
|
2008-04-28 |
2011-04-13 |
默沙东公司 |
Hcv ns3蛋白酶抑制剂
|
|
CN102046648A
(zh)
|
2008-05-29 |
2011-05-04 |
百时美施贵宝公司 |
丙型肝炎病毒抑制剂
|
|
US7964560B2
(en)
|
2008-05-29 |
2011-06-21 |
Bristol-Myers Squibb Company |
Hepatitis C virus inhibitors
|
|
JP5580814B2
(ja)
|
2008-06-13 |
2014-08-27 |
メルク・シャープ・アンド・ドーム・コーポレーション |
3環式インドール誘導体およびその使用方法
|
|
KR20110065440A
(ko)
|
2008-07-02 |
2011-06-15 |
아이데닉스 파마슈티칼스, 인코포레이티드 |
바이러스 감염의 치료를 위한 화합물 및 제약 조성물
|
|
ES2392611T3
(es)
|
2008-07-22 |
2012-12-12 |
Merck Sharp & Dohme Corp. |
Compuestos de quinoxalina macrocíclica como inhibidores de la proteasa NS3 del VHC
|
|
US8470834B2
(en)
|
2008-08-20 |
2013-06-25 |
Merck Sharp & Dohme Corp. |
AZO-substituted pyridine and pyrimidine derivatives and their use in treating viral infections
|
|
CA2734487A1
(en)
|
2008-08-20 |
2010-02-25 |
Southern Research Institute |
Ethynyl-substituted pyridine and pyrimidine derivatives and their use in treating viral infections
|
|
WO2010022121A1
(en)
|
2008-08-20 |
2010-02-25 |
Schering Corporation |
Substituted pyridine and pyrimidine derivatives and their use in treating viral infections
|
|
WO2010022128A1
(en)
|
2008-08-20 |
2010-02-25 |
Schering Corporation |
Ethenyl-substituted pyridine and pyrimidine derivatives and their use in treating viral infections
|
|
US8207341B2
(en)
|
2008-09-04 |
2012-06-26 |
Bristol-Myers Squibb Company |
Process or synthesizing substituted isoquinolines
|
|
US8044087B2
(en)
|
2008-09-29 |
2011-10-25 |
Bristol-Myers Squibb Company |
Hepatitis C virus inhibitors
|
|
US8563505B2
(en)
|
2008-09-29 |
2013-10-22 |
Bristol-Myers Squibb Company |
Hepatitis C virus inhibitors
|
|
EP2341924A4
(en)
|
2008-10-02 |
2013-01-23 |
David Gladstone Inst |
METHOD FOR THE TREATMENT OF HEPATITIS C VIRUS INFECTIONS
|
|
WO2010065668A1
(en)
|
2008-12-03 |
2010-06-10 |
Presidio Pharmaceuticals, Inc. |
Inhibitors of hcv ns5a
|
|
AU2009322393B2
(en)
|
2008-12-03 |
2017-02-02 |
Presidio Pharmaceuticals, Inc. |
Inhibitors of HCV NS5A
|
|
US8283310B2
(en)
|
2008-12-15 |
2012-10-09 |
Bristol-Myers Squibb Company |
Hepatitis C virus inhibitors
|
|
CL2009002206A1
(es)
|
2008-12-23 |
2011-08-26 |
Gilead Pharmasset Llc |
Compuestos derivados de pirrolo -(2-3-d]-pirimidin-7(6h)-tetrahidrofuran-2-il fosfonamidato, composicion farmaceutica; y su uso en el tratamiento de enfermedades virales.
|
|
AR074897A1
(es)
|
2008-12-23 |
2011-02-23 |
Pharmasset Inc |
Fosforamidatos de nucleosidos
|
|
MX2011006890A
(es)
|
2008-12-23 |
2011-07-20 |
Pharmasset Inc |
Analogos de nucleosidos.
|
|
KR20110116136A
(ko)
|
2009-01-07 |
2011-10-25 |
싸이넥시스, 인크. |
Hcv 및 hiv 감염의 치료에 사용하기 위한 사이클로스포린 유도체
|
|
WO2010082050A1
(en)
|
2009-01-16 |
2010-07-22 |
Istituto Di Ricerche Di Biologia Molecolare P. Angeletti S.P.A. |
Macrocyclic and 7-aminoalkyl-substituted benzoxazocines for treatment of hepatitis c infections
|
|
GB0900914D0
(en)
|
2009-01-20 |
2009-03-04 |
Angeletti P Ist Richerche Bio |
Antiviral agents
|
|
US8102720B2
(en)
*
|
2009-02-02 |
2012-01-24 |
Qualcomm Incorporated |
System and method of pulse generation
|
|
WO2010101967A2
(en)
|
2009-03-04 |
2010-09-10 |
Idenix Pharmaceuticals, Inc. |
Phosphothiophene and phosphothiazole hcv polymerase inhibitors
|
|
CN102448458B
(zh)
|
2009-03-18 |
2015-07-22 |
小利兰·斯坦福大学理事会 |
治疗黄病毒科病毒感染的方法和组合物
|
|
EA201190224A1
(ru)
|
2009-03-27 |
2012-03-30 |
Пресидио Фармасьютикалс, Инк. |
Ингибиторы гепатита c, содержащие конденсированные кольца
|
|
TW201040181A
(en)
|
2009-04-08 |
2010-11-16 |
Idenix Pharmaceuticals Inc |
Macrocyclic serine protease inhibitors
|
|
US20110182850A1
(en)
|
2009-04-10 |
2011-07-28 |
Trixi Brandl |
Organic compounds and their uses
|
|
US8512690B2
(en)
|
2009-04-10 |
2013-08-20 |
Novartis Ag |
Derivatised proline containing peptide compounds as protease inhibitors
|
|
CA2761650C
(en)
|
2009-05-13 |
2015-05-26 |
Enanta Pharmaceuticals, Inc. |
Macrocyclic compounds as hepatitis c virus inhibitors
|
|
TWI576352B
(zh)
|
2009-05-20 |
2017-04-01 |
基利法瑪席特有限責任公司 |
核苷磷醯胺
|
|
US8618076B2
(en)
|
2009-05-20 |
2013-12-31 |
Gilead Pharmasset Llc |
Nucleoside phosphoramidates
|
|
JP2012528195A
(ja)
|
2009-05-29 |
2012-11-12 |
メルク・シャープ・アンド・ドーム・コーポレーション |
C型肝炎などの疾患を処置するための3つの結合アリール部分で構成された抗菌性化合物
|
|
US8828930B2
(en)
|
2009-07-30 |
2014-09-09 |
Merck Sharp & Dohme Corp. |
Hepatitis C virus NS3 protease inhibitors
|
|
AR077712A1
(es)
|
2009-08-05 |
2011-09-14 |
Idenix Pharmaceuticals Inc |
Inhibidores de serina proteasa macrociclica
|
|
EP2477980B1
(en)
|
2009-09-15 |
2016-06-08 |
Taigen Biotechnology Co., Ltd. |
Hcv protease inhibitors
|
|
WO2011063076A1
(en)
|
2009-11-19 |
2011-05-26 |
Itherx Pharmaceuticals, Inc. |
Methods of treating hepatitis c virus with oxoacetamide compounds
|
|
WO2011066241A1
(en)
|
2009-11-25 |
2011-06-03 |
Schering Corporation |
Fused tricyclic compounds and derivatives thereof useful for the treatment of viral diseases
|
|
EP2504329A1
(en)
|
2009-11-25 |
2012-10-03 |
Vertex Pharmaceuticals Incorporated |
5-alkynyl-thiophene-2-carboxylic acid derivatives and their use for the treatment or prevention of flavivirus infections
|
|
MY159958A
(en)
|
2009-12-18 |
2017-02-15 |
Idenix Pharmaceuticals Inc |
5,5-fused arylene or heteroarylene hepatitis c virus inhibitors
|
|
WO2011087740A1
(en)
|
2009-12-22 |
2011-07-21 |
Schering Corporation |
Fused tricyclic compounds and methods of use thereof for the treatment of viral diseases
|
|
CN102883718A
(zh)
|
2009-12-24 |
2013-01-16 |
顶点制药公司 |
用于治疗或预防黄病毒感染的类似物
|
|
CA2788155C
(en)
|
2010-01-27 |
2018-04-24 |
AB Pharma Ltd. |
Polyheterocyclic compounds highly potent as hcv inhibitors
|
|
US9433621B2
(en)
|
2010-02-18 |
2016-09-06 |
Merck Sharp & Dohme Corp. |
Substituted pyridine and pyrimidine derivatives and their use in treating viral infections
|
|
WO2011112516A1
(en)
|
2010-03-08 |
2011-09-15 |
Ico Therapeutics Inc. |
Treating and preventing hepatitis c virus infection using c-raf kinase antisense oligonucleotides
|
|
MA34147B1
(fr)
|
2010-03-09 |
2013-04-03 |
Merck Sharp & Dohme |
Composes tricycliques fusionnes de silyle et leurs methodes d'utilisation dans le cadre du traitement de maladies virales
|
|
WO2011119853A1
(en)
|
2010-03-24 |
2011-09-29 |
Vertex Pharmaceuticals Incorporated |
Analogues for the treatment or prevention of flavivirus infections
|
|
TW201139438A
(en)
|
2010-03-24 |
2011-11-16 |
Vertex Pharma |
Analogues for the treatment or prevention of flavivirus infections
|
|
CA2794181A1
(en)
|
2010-03-24 |
2011-09-29 |
Vertex Pharmaceuticals Incorporated |
Analogues for the treatment or prevention of flavivirus infections
|
|
TW201141857A
(en)
|
2010-03-24 |
2011-12-01 |
Vertex Pharma |
Analogues for the treatment or prevention of flavivirus infections
|
|
AP2012006535A0
(en)
|
2010-03-31 |
2012-10-31 |
Gilead Pharmasset Llc |
Stereoselective synthesis of phosphorous containing actives
|
|
TWI515000B
(zh)
|
2010-04-01 |
2016-01-01 |
伊迪尼克製藥公司 |
用於治療病毒感染之化合物及醫藥組合物
|
|
CA2800509A1
(en)
|
2010-05-24 |
2011-12-01 |
Presidio Pharmaceuticals, Inc. |
Inhibitors of hcv ns5a
|
|
WO2011156545A1
(en)
|
2010-06-09 |
2011-12-15 |
Vertex Pharmaceuticals Incorporated |
Viral dynamic model for hcv combination therapy
|
|
WO2011159826A2
(en)
|
2010-06-15 |
2011-12-22 |
Vertex Pharmaceuticals Incorporated |
Hcv ns5b protease mutants
|
|
JP2013531011A
(ja)
|
2010-06-28 |
2013-08-01 |
バーテックス ファーマシューティカルズ インコーポレイテッド |
フラビウイルス感染の処置または予防のための化合物および方法
|
|
JP2013529684A
(ja)
|
2010-06-28 |
2013-07-22 |
バーテックス ファーマシューティカルズ インコーポレイテッド |
フラビウイルス感染の処置または予防のための化合物および方法
|
|
WO2012006070A1
(en)
|
2010-06-28 |
2012-01-12 |
Vertex Pharmaceuticals Incorporated |
Compounds and methods for the treatment or prevention of flavivirus infections
|
|
CA2805440A1
(en)
|
2010-07-26 |
2012-02-09 |
Merck Sharp & Dohme Corp. |
Substituted biphenylene compounds and methods of use thereof for the treatment of viral diseases
|
|
AR082619A1
(es)
|
2010-08-13 |
2012-12-19 |
Hoffmann La Roche |
Inhibidores del virus de la hepatitis c
|
|
CA2808291A1
(en)
|
2010-08-17 |
2012-02-23 |
Vertex Pharmaceuticals Incorporated |
Compounds and methods for the treatment or prevention of flaviviridae viral infections
|
|
TWI523658B
(zh)
|
2010-09-21 |
2016-03-01 |
安塔製藥公司 |
巨環脯胺酸衍生之hcv絲胺酸蛋白酶抑制劑
|
|
EP2621279B1
(en)
|
2010-09-29 |
2018-04-04 |
Merck Sharp & Dohme Corp. |
Fused tetracycle derivatives and methods of use thereof for the treatment of viral diseases
|
|
CN103179966B
(zh)
|
2010-10-08 |
2017-03-15 |
诺瓦提斯公司 |
磺酰胺ns3抑制剂的维生素e制剂
|
|
ES2716158T3
(es)
|
2010-11-30 |
2019-06-10 |
Gilead Pharmasset Llc |
2'-spiro-nucleótidos para el tratamiento de hepatitis C
|
|
TW201309690A
(zh)
|
2011-02-10 |
2013-03-01 |
Idenix Pharmaceuticals Inc |
巨環絲胺酸蛋白酶抑制劑,其醫藥組合物及其於治療hcv感染之用途
|
|
WO2012107589A1
(en)
|
2011-02-11 |
2012-08-16 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
Methods and pharmaceutical compositions for the treatment and prevention of hcv infections
|
|
WO2012123298A1
(en)
|
2011-03-11 |
2012-09-20 |
F. Hoffmann-La Roche Ag |
Antiviral compounds
|
|
US9243025B2
(en)
|
2011-03-31 |
2016-01-26 |
Idenix Pharmaceuticals, Llc |
Compounds and pharmaceutical compositions for the treatment of viral infections
|
|
US20120252721A1
(en)
|
2011-03-31 |
2012-10-04 |
Idenix Pharmaceuticals, Inc. |
Methods for treating drug-resistant hepatitis c virus infection with a 5,5-fused arylene or heteroarylene hepatitis c virus inhibitor
|
|
EP2697242B1
(en)
|
2011-04-13 |
2018-10-03 |
Merck Sharp & Dohme Corp. |
2'-azido substituted nucleoside derivatives and methods of use thereof for the treatment of viral diseases
|
|
US8957203B2
(en)
|
2011-05-05 |
2015-02-17 |
Bristol-Myers Squibb Company |
Hepatitis C virus inhibitors
|
|
US8691757B2
(en)
|
2011-06-15 |
2014-04-08 |
Bristol-Myers Squibb Company |
Hepatitis C virus inhibitors
|
|
US8962810B2
(en)
|
2011-06-16 |
2015-02-24 |
AB Pharma Ltd. |
Macrocyclic heterocyclic compound for inhibiting hepatitis C virus and preparation and use thereof
|
|
BR112013032188A2
(pt)
|
2011-06-23 |
2016-12-20 |
Digna Biotech Sl |
composição, produto e método para tratar pacientes com hepatite c crônica
|
|
WO2012175581A1
(en)
|
2011-06-24 |
2012-12-27 |
F. Hoffmann-La Roche Ag |
Antiviral compounds
|
|
WO2013016499A1
(en)
|
2011-07-26 |
2013-01-31 |
Vertex Pharmaceuticals Incorporated |
Methods for preparation of thiophene compounds
|
|
WO2013016491A1
(en)
|
2011-07-26 |
2013-01-31 |
Vertex Pharmaceuticals Incorporated |
Thiophene compounds
|
|
WO2013033900A1
(en)
|
2011-09-08 |
2013-03-14 |
Merck Sharp & Dohme Corp. |
Tetracyclic heterocycle compounds and methods of use thereof for the treatment of viral diseases
|
|
WO2013033899A1
(en)
|
2011-09-08 |
2013-03-14 |
Merck Sharp & Dohme Corp. |
Substituted benzofuran compounds and methods of use thereof for the treatment of viral diseases
|
|
WO2013033901A1
(en)
|
2011-09-08 |
2013-03-14 |
Merck Sharp & Dohme Corp. |
Heterocyclic-substituted benzofuran derivatives and methods of use thereof for the treatment of viral diseases
|
|
AU2012308900A1
(en)
|
2011-09-12 |
2013-05-09 |
Idenix Pharmaceuticals, Inc. |
Compounds and pharmaceutical compositions for the treatment of viral infections
|
|
US9403863B2
(en)
|
2011-09-12 |
2016-08-02 |
Idenix Pharmaceuticals Llc |
Substituted carbonyloxymethylphosphoramidate compounds and pharmaceutical compositions for the treatment of viral infections
|
|
US20140378416A1
(en)
|
2011-09-14 |
2014-12-25 |
Michael P. Dwyer |
Silyl-containing heterocyclic compounds and methods of use thereof for the treatment of viral diseases
|
|
KR101621181B1
(ko)
|
2011-10-10 |
2016-05-13 |
에프. 호프만-라 로슈 아게 |
항바이러스성 화합물
|
|
AR089650A1
(es)
|
2011-10-14 |
2014-09-10 |
Idenix Pharmaceuticals Inc |
Fosfatos 3,5-ciclicos sustituidos de compuestos de nucleotido de purina y composiciones farmaceuticas para el tratamiento de infecciones virales
|
|
US9328138B2
(en)
|
2011-11-15 |
2016-05-03 |
Msd Italia S.R.L. |
HCV NS3 protease inhibitors
|
|
US8889159B2
(en)
|
2011-11-29 |
2014-11-18 |
Gilead Pharmasset Llc |
Compositions and methods for treating hepatitis C virus
|
|
US9089574B2
(en)
|
2011-11-30 |
2015-07-28 |
Emory University |
Antiviral JAK inhibitors useful in treating or preventing retroviral and other viral infections
|
|
MX349036B
(es)
|
2011-12-06 |
2017-07-07 |
Univ Leland Stanford Junior |
Metodos y composiciones para tratar enfermedades virales.
|
|
CN103987723B
(zh)
|
2011-12-16 |
2017-03-01 |
弗·哈夫曼-拉罗切有限公司 |
Hcv ns5a 的抑制剂
|
|
EA024297B1
(ru)
|
2011-12-20 |
2016-09-30 |
Рибосайенс Ллк |
2',4'-дифтор-2'-метилзамещенные нуклеозидные производные в качестве ингибиторов репликации рнк вируса гепатита с
|
|
IN2014CN04530A
(pt)
|
2011-12-20 |
2015-09-11 |
Hoffmann La Roche |
|
|
US8809354B2
(en)
|
2011-12-31 |
2014-08-19 |
Sheikh Riazuddin |
3-amino-2-(4-nitrophenyl)-4-(3H)-quinazolinone or derivatives thereof for treating or preventing antiviral infections
|
|
WO2013106344A1
(en)
|
2012-01-12 |
2013-07-18 |
Ligand Pharmaceuticals, Inc. |
2 '-c-methyl nucleosides containing a cyclic phosphate diester of 1, 3-propanediol (2-oxo-[1, 3, 2]-dioxaphosphorinane) at position 5'
|
|
WO2013133927A1
(en)
|
2012-02-13 |
2013-09-12 |
Idenix Pharmaceuticals, Inc. |
Pharmaceutical compositions of 2'-c-methyl-guanosine, 5'-[2-[(3-hydroxy-2,2-dimethyl-1-oxopropyl)thio]ethyl n-(phenylmethyl)phosphoramidate]
|
|
CN104185624B
(zh)
|
2012-02-24 |
2016-10-12 |
弗·哈夫曼-拉罗切有限公司 |
抗病毒化合物
|
|
NZ630805A
(en)
|
2012-03-22 |
2016-01-29 |
Alios Biopharma Inc |
Pharmaceutical combinations comprising a thionucleotide analog
|
|
WO2013177195A1
(en)
|
2012-05-22 |
2013-11-28 |
Idenix Pharmaceuticals, Inc. |
3',5'-cyclic phosphate prodrugs for hcv infection
|
|
MD20140134A2
(ro)
|
2012-05-22 |
2015-04-30 |
Idenix Pharmaceuticals, Inc. |
Compuşi ai D-aminoacizilor pentru tratamentul bolilor hepatice
|
|
EP2852604B1
(en)
|
2012-05-22 |
2017-04-12 |
Idenix Pharmaceuticals LLC |
3',5'-cyclic phosphoramidate prodrugs for hcv infection
|
|
US20140010783A1
(en)
|
2012-07-06 |
2014-01-09 |
Hoffmann-La Roche Inc. |
Antiviral compounds
|
|
ES2674980T3
(es)
|
2012-10-08 |
2018-07-05 |
Idenix Pharmaceuticals Llc |
Análogos de 2'-cloro nucleósidos para infección por VHC
|
|
EP2909223B1
(en)
|
2012-10-19 |
2017-03-22 |
Idenix Pharmaceuticals LLC |
Dinucleotide compounds for hcv infection
|
|
JP6154474B2
(ja)
|
2012-10-19 |
2017-06-28 |
ブリストル−マイヤーズ スクイブ カンパニーBristol−Myers Squibb Company |
C型肝炎ウイルス阻害剤
|
|
WO2014066239A1
(en)
|
2012-10-22 |
2014-05-01 |
Idenix Pharmaceuticals, Inc. |
2',4'-bridged nucleosides for hcv infection
|
|
WO2014071007A1
(en)
|
2012-11-02 |
2014-05-08 |
Bristol-Myers Squibb Company |
Hepatitis c virus inhibitors
|
|
US9643999B2
(en)
|
2012-11-02 |
2017-05-09 |
Bristol-Myers Squibb Company |
Hepatitis C virus inhibitors
|
|
EP2914613B1
(en)
|
2012-11-02 |
2017-11-22 |
Bristol-Myers Squibb Company |
Hepatitis c virus inhibitors
|
|
EP2914614B1
(en)
|
2012-11-05 |
2017-08-16 |
Bristol-Myers Squibb Company |
Hepatitis c virus inhibitors
|
|
WO2014078427A1
(en)
|
2012-11-14 |
2014-05-22 |
Idenix Pharmaceuticals, Inc. |
D-alanine ester of rp-nucleoside analog
|
|
WO2014078436A1
(en)
|
2012-11-14 |
2014-05-22 |
Idenix Pharmaceuticals, Inc. |
D-alanine ester of sp-nucleoside analog
|
|
US9211300B2
(en)
|
2012-12-19 |
2015-12-15 |
Idenix Pharmaceuticals Llc |
4′-fluoro nucleosides for the treatment of HCV
|
|
MX2015009176A
(es)
|
2013-01-23 |
2015-11-09 |
Hoffmann La Roche |
Derivados de triazola antivirales.
|
|
WO2014121418A1
(en)
|
2013-02-07 |
2014-08-14 |
Merck Sharp & Dohme Corp. |
Tetracyclic heterocycle compounds and methods of use thereof for the treatment of hepatitis c
|
|
WO2014121417A1
(en)
|
2013-02-07 |
2014-08-14 |
Merck Sharp & Dohme Corp. |
Tetracyclic heterocycle compounds and methods of use thereof for the treatment of hepatitis c
|
|
US20150065439A1
(en)
|
2013-02-28 |
2015-03-05 |
Vertex Pharmaceuticals Incorporated |
Pharmaceutical compositions
|
|
WO2014137926A1
(en)
|
2013-03-04 |
2014-09-12 |
Idenix Pharmaceuticals, Inc. |
3'-deoxy nucleosides for the treatment of hcv
|
|
WO2014137930A1
(en)
|
2013-03-04 |
2014-09-12 |
Idenix Pharmaceuticals, Inc. |
Thiophosphate nucleosides for the treatment of hcv
|
|
WO2014135422A1
(en)
|
2013-03-05 |
2014-09-12 |
F. Hoffmann-La Roche Ag |
Antiviral compounds
|
|
EP2964664B1
(en)
|
2013-03-07 |
2017-01-11 |
Bristol-Myers Squibb Company |
Hepatitis c virus inhibitors
|
|
EP2981542B1
(en)
|
2013-04-01 |
2021-09-15 |
Idenix Pharmaceuticals LLC |
2',4'-fluoro nucleosides for the treatment of hcv
|
|
AU2014265293B2
(en)
|
2013-05-16 |
2019-07-18 |
Riboscience Llc |
4'-Fluoro-2'-methyl substituted nucleoside derivatives
|
|
MX2015015781A
(es)
|
2013-05-16 |
2016-06-02 |
Riboscience Llc |
Derivados de nucleósido 4'-azido, 3'-deoxi-3'-fluoro sustituido.
|
|
US20180200280A1
(en)
|
2013-05-16 |
2018-07-19 |
Riboscience Llc |
4'-Fluoro-2'-Methyl Substituted Nucleoside Derivatives as Inhibitors of HCV RNA Replication
|
|
EP3004130B1
(en)
|
2013-06-05 |
2019-08-07 |
Idenix Pharmaceuticals LLC. |
1',4'-thio nucleosides for the treatment of hcv
|
|
US20150037282A1
(en)
|
2013-08-01 |
2015-02-05 |
Idenix Pharmaceuticals, Inc. |
D-amino acid phosphoramidate pronucleotides of halogeno pyrimidine compounds for liver disease
|
|
EA201690473A1
(ru)
|
2013-08-27 |
2017-03-31 |
ГАЙЛИД ФАРМАССЕТ ЭлЭлСи |
Комбинированный состав двух противовирусных соединений
|
|
EP3046924A1
(en)
|
2013-09-20 |
2016-07-27 |
IDENIX Pharmaceuticals, Inc. |
Hepatitis c virus inhibitors
|
|
WO2015061683A1
(en)
|
2013-10-25 |
2015-04-30 |
Idenix Pharmaceuticals, Inc. |
D-amino acid phosphoramidate and d-alanine thiophosphoramidate pronucleotides of nucleoside compounds useful for the treatment of hcv
|
|
WO2015065817A1
(en)
|
2013-10-30 |
2015-05-07 |
Merck Sharp & Dohme Corp. |
Pseudopolymorphs of an hcv ns5a inhibitor and uses thereof
|
|
WO2015066370A1
(en)
|
2013-11-01 |
2015-05-07 |
Idenix Pharmaceuticals, Inc. |
D-alanine phosphoramidate pronucleotides of 2'-methyl 2'-fluoro guanosine nucleoside compounds for the treatment of hcv
|
|
EP3074399A1
(en)
|
2013-11-27 |
2016-10-05 |
Idenix Pharmaceuticals LLC |
2'-dichloro and 2'-fluoro-2'-chloro nucleoside analogues for hcv infection
|
|
WO2015095419A1
(en)
|
2013-12-18 |
2015-06-25 |
Idenix Pharmaceuticals, Inc. |
4'-or nucleosides for the treatment of hcv
|
|
EP2899207A1
(en)
|
2014-01-28 |
2015-07-29 |
Amikana.Biologics |
New method for testing HCV protease inhibition
|
|
EP3623364A1
(en)
|
2014-02-13 |
2020-03-18 |
Ligand Pharmaceuticals, Inc. |
Prodrug compounds and their uses
|
|
US20170135990A1
(en)
|
2014-03-05 |
2017-05-18 |
Idenix Pharmaceuticals Llc |
Pharmaceutical compositions comprising a 5,5-fused heteroarylene flaviviridae inhibitor and their use for treating or preventing flaviviridae infection
|
|
WO2015134560A1
(en)
|
2014-03-05 |
2015-09-11 |
Idenix Pharmaceuticals, Inc. |
Solid forms of a flaviviridae virus inhibitor compound and salts thereof
|
|
EP3131914B1
(en)
|
2014-04-16 |
2023-05-10 |
Idenix Pharmaceuticals LLC |
3'-substituted methyl or alkynyl nucleosides for the treatment of hcv
|
|
CN106687118A
(zh)
|
2014-07-02 |
2017-05-17 |
配体药物公司 |
前药化合物及其用途
|
|
CN108699106B
(zh)
|
2016-03-04 |
2021-11-30 |
豪夫迈·罗氏有限公司 |
作为htra1抑制剂的新型三氟甲基丙酰胺衍生物
|
|
EP3423467B1
(en)
|
2016-03-04 |
2021-04-28 |
F. Hoffmann-La Roche AG |
New difluoroketamide derivatives as htra1 inhibitors
|
|
JP7179721B2
(ja)
|
2016-06-21 |
2022-11-29 |
オリオン・オフサルモロジー・エルエルシー |
複素環式プロリンアミド誘導体
|
|
JP7164521B2
(ja)
|
2016-06-21 |
2022-11-01 |
オリオン・オフサルモロジー・エルエルシー |
炭素環式プロリンアミド誘導体
|
|
CN109415330A
(zh)
|
2016-07-18 |
2019-03-01 |
豪夫迈·罗氏有限公司 |
作为htra1抑制剂的新型二氟酮酰胺衍生物
|
|
WO2018032467A1
(en)
|
2016-08-18 |
2018-02-22 |
Merck Sharp & Dohme Corp. |
Chromane-substitued tetracyclic compounds and uses thereof for treatment of viral diseases
|
|
WO2018032468A1
(en)
|
2016-08-18 |
2018-02-22 |
Merck Sharp & Dohme Corp. |
Heterocycle-substitued tetracyclic compounds and methods of use thereof for treatment of viral diseases
|
|
WO2018036942A1
(en)
|
2016-08-23 |
2018-03-01 |
F. Hoffmann-La Roche Ag |
New difluoroketamide derivatives as htra1 inhibitors
|
|
WO2018036957A1
(en)
*
|
2016-08-23 |
2018-03-01 |
F. Hoffmann-La Roche Ag |
New trifluoromethylpropanamide derivatives as htra1 inhibitors
|
|
EP3684374B1
(en)
|
2017-09-21 |
2025-07-30 |
Riboscience LLC |
4'-fluoro-2'-methyl substituted nucleoside derivatives as inhibitors of hcv rna replication
|
|
WO2019139919A1
(en)
|
2018-01-09 |
2019-07-18 |
Ligand Pharmaceuticals, Inc. |
Acetal compounds and therapeutic uses thereof
|
|
US20220099637A1
(en)
|
2018-12-04 |
2022-03-31 |
Bristol-Myers Squibb Company |
Methods of analysis using in-sample calibration curve by multiple isotopologue reaction monitoring
|