PT1040106E - Derivados de cromano substituidos com carboxi uteis como agonistas de adrenoreceptor beta 3 - Google Patents
Derivados de cromano substituidos com carboxi uteis como agonistas de adrenoreceptor beta 3Info
- Publication number
- PT1040106E PT1040106E PT98963240T PT98963240T PT1040106E PT 1040106 E PT1040106 E PT 1040106E PT 98963240 T PT98963240 T PT 98963240T PT 98963240 T PT98963240 T PT 98963240T PT 1040106 E PT1040106 E PT 1040106E
- Authority
- PT
- Portugal
- Prior art keywords
- uteis
- carboxy
- chroman derivatives
- derivatives substituted
- adrenoreceptor agonists
- Prior art date
Links
- 125000003178 carboxy group Chemical group [H]OC(*)=O 0.000 title abstract 2
- VZWXIQHBIQLMPN-UHFFFAOYSA-N chromane Chemical group C1=CC=C2CCCOC2=C1 VZWXIQHBIQLMPN-UHFFFAOYSA-N 0.000 title abstract 2
- 229940123031 Beta adrenoreceptor agonist Drugs 0.000 title 1
- 230000001404 mediated effect Effects 0.000 abstract 1
- 102000005962 receptors Human genes 0.000 abstract 1
- 108020003175 receptors Proteins 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/04—Anorexiants; Antiobesity agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
- C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D311/04—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring
- C07D311/58—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring other than with oxygen or sulphur atoms in position 2 or 4
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Diabetes (AREA)
- Veterinary Medicine (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Public Health (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Engineering & Computer Science (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Obesity (AREA)
- Hematology (AREA)
- Neurosurgery (AREA)
- Emergency Medicine (AREA)
- Endocrinology (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Child & Adolescent Psychology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Pyrane Compounds (AREA)
- Peptides Or Proteins (AREA)
- Pyrrole Compounds (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
- Solid-Sorbent Or Filter-Aiding Compositions (AREA)
- Detergent Compositions (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US99462097A | 1997-12-19 | 1997-12-19 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| PT1040106E true PT1040106E (pt) | 2002-11-29 |
Family
ID=25540853
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PT98963240T PT1040106E (pt) | 1997-12-19 | 1998-12-16 | Derivados de cromano substituidos com carboxi uteis como agonistas de adrenoreceptor beta 3 |
Country Status (24)
| Country | Link |
|---|---|
| EP (1) | EP1040106B1 (pt) |
| JP (1) | JP2001526282A (pt) |
| KR (1) | KR20010033188A (pt) |
| CN (1) | CN1284952A (pt) |
| AT (1) | ATE222901T1 (pt) |
| AU (1) | AU749097B2 (pt) |
| BG (1) | BG104593A (pt) |
| BR (1) | BR9814302A (pt) |
| CA (1) | CA2316971A1 (pt) |
| DE (1) | DE69807523T2 (pt) |
| DK (1) | DK1040106T3 (pt) |
| ES (1) | ES2183434T3 (pt) |
| HU (1) | HUP0004565A3 (pt) |
| ID (1) | ID26524A (pt) |
| IL (1) | IL136689A0 (pt) |
| NO (1) | NO20003083L (pt) |
| NZ (1) | NZ505200A (pt) |
| PL (1) | PL341229A1 (pt) |
| PT (1) | PT1040106E (pt) |
| RU (1) | RU2223269C2 (pt) |
| SK (1) | SK9362000A3 (pt) |
| TR (1) | TR200001927T2 (pt) |
| UA (1) | UA62993C2 (pt) |
| WO (1) | WO1999032476A1 (pt) |
Families Citing this family (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AR035605A1 (es) | 2000-12-11 | 2004-06-16 | Bayer Corp | Derivados de aminometil cromano di-sustituidos, un metodo para su preparacion, composiciones farmaceuticas y el uso de dichos derivados para la manufactura de medicamentos utiles como agonistas beta-3-adreno-receptores |
| AR035858A1 (es) * | 2001-04-23 | 2004-07-21 | Bayer Corp | Derivados de cromano 2,6-sustituidos,composiciones farmaceuticas,uso de dichos derivados para la manufactura de medicamentos utiles como agonistas adrenorreceptores beta-3 |
| US20040265991A1 (en) * | 2001-10-17 | 2004-12-30 | Naoaki Taoka | Process for preparation of (s)-alpha-halomethylpyridine-methanol derivatives |
| MY147767A (en) * | 2004-06-16 | 2013-01-31 | Janssen Pharmaceutica Nv | Novel sulfamate and sulfamide derivatives useful for the treatment of epilepsy and related disorders |
| JP2008530229A (ja) | 2005-02-17 | 2008-08-07 | ワイス | シクロアルキル縮合インドール、ベンゾチオフェン、ベンゾフランおよびインデン誘導体 |
| EP1803716B1 (en) * | 2005-12-28 | 2012-07-25 | Acino Pharma AG | A process for preparation of racemic nebivolol |
| US7560575B2 (en) | 2005-12-28 | 2009-07-14 | Acino Pharma Ag | Process for preparation of racemic Nebivolol |
| RU2392277C2 (ru) * | 2005-12-28 | 2010-06-20 | Асино Фарма Аг | Способ получения рацемического небиволола |
| ES2534336B1 (es) * | 2013-10-18 | 2016-01-28 | Artax Biopharma Inc. | Derivados de cromeno como inhibidores de la interacción TCR-Nck |
| ES2534318B1 (es) * | 2013-10-18 | 2016-01-28 | Artax Biopharma Inc. | Derivados de cromeno sustituidos por alcóxido como inhibidores de la interacción TCR-Nck |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA1337429C (en) * | 1983-12-05 | 1995-10-24 | Guy Rosalia Eugene Van Lommen | Derivatives of 2,2'-iminobisethanol |
| GB8801306D0 (en) * | 1988-01-21 | 1988-02-17 | Ici Plc | Chemical compounds |
| RU2032684C1 (ru) * | 1991-04-08 | 1995-04-10 | Джон Вайс энд Бразер Лимитед | Способ получения производных 4-оксохинолина или хромона или их фармацевтически приемлемых солей |
| US5451677A (en) * | 1993-02-09 | 1995-09-19 | Merck & Co., Inc. | Substituted phenyl sulfonamides as selective β 3 agonists for the treatment of diabetes and obesity |
| BR9406823A (pt) * | 1993-06-14 | 1996-03-26 | Pfizer | Aminas secundárias e agentes anti-diabéticos e antiobesidade |
| GB9405019D0 (en) * | 1994-03-15 | 1994-04-27 | Smithkline Beecham Plc | Novel compounds |
| US5561142A (en) * | 1994-04-26 | 1996-10-01 | Merck & Co., Inc. | Substituted sulfonamides as selective β3 agonists for the treatment of diabetes and obesity |
| EP0801060A1 (en) * | 1996-04-09 | 1997-10-15 | Pfizer Inc. | Heterocyclic Beta-3 Adrenergenic Agonists |
-
1998
- 1998-12-16 JP JP2000525413A patent/JP2001526282A/ja not_active Withdrawn
- 1998-12-16 SK SK936-2000A patent/SK9362000A3/sk unknown
- 1998-12-16 UA UA2000074336A patent/UA62993C2/uk unknown
- 1998-12-16 CN CN98813619A patent/CN1284952A/zh active Pending
- 1998-12-16 IL IL13668998A patent/IL136689A0/xx unknown
- 1998-12-16 RU RU2000119110/04A patent/RU2223269C2/ru not_active IP Right Cessation
- 1998-12-16 WO PCT/US1998/026735 patent/WO1999032476A1/en not_active Ceased
- 1998-12-16 PT PT98963240T patent/PT1040106E/pt unknown
- 1998-12-16 ID IDW20001393A patent/ID26524A/id unknown
- 1998-12-16 DE DE69807523T patent/DE69807523T2/de not_active Expired - Fee Related
- 1998-12-16 ES ES98963240T patent/ES2183434T3/es not_active Expired - Lifetime
- 1998-12-16 NZ NZ505200A patent/NZ505200A/xx unknown
- 1998-12-16 AU AU18300/99A patent/AU749097B2/en not_active Ceased
- 1998-12-16 BR BR9814302-6A patent/BR9814302A/pt not_active IP Right Cessation
- 1998-12-16 PL PL98341229A patent/PL341229A1/xx not_active Application Discontinuation
- 1998-12-16 CA CA002316971A patent/CA2316971A1/en not_active Abandoned
- 1998-12-16 AT AT98963240T patent/ATE222901T1/de not_active IP Right Cessation
- 1998-12-16 EP EP98963240A patent/EP1040106B1/en not_active Expired - Lifetime
- 1998-12-16 KR KR1020007006572A patent/KR20010033188A/ko not_active Ceased
- 1998-12-16 HU HU0004565A patent/HUP0004565A3/hu unknown
- 1998-12-16 TR TR2000/01927T patent/TR200001927T2/xx unknown
- 1998-12-16 DK DK98963240T patent/DK1040106T3/da active
-
2000
- 2000-06-15 NO NO20003083A patent/NO20003083L/no not_active Application Discontinuation
- 2000-07-11 BG BG104593A patent/BG104593A/xx unknown
Also Published As
| Publication number | Publication date |
|---|---|
| UA62993C2 (en) | 2004-01-15 |
| ATE222901T1 (de) | 2002-09-15 |
| AU1830099A (en) | 1999-07-12 |
| PL341229A1 (en) | 2001-03-26 |
| NO20003083D0 (no) | 2000-06-15 |
| EP1040106B1 (en) | 2002-08-28 |
| NO20003083L (no) | 2000-08-15 |
| IL136689A0 (en) | 2001-06-14 |
| EP1040106A1 (en) | 2000-10-04 |
| DE69807523T2 (de) | 2003-01-09 |
| KR20010033188A (ko) | 2001-04-25 |
| DE69807523D1 (de) | 2002-10-02 |
| WO1999032476A1 (en) | 1999-07-01 |
| BR9814302A (pt) | 2000-10-10 |
| ID26524A (id) | 2001-01-11 |
| SK9362000A3 (en) | 2001-09-11 |
| BG104593A (en) | 2001-09-28 |
| JP2001526282A (ja) | 2001-12-18 |
| DK1040106T3 (da) | 2002-12-02 |
| HUP0004565A2 (hu) | 2001-08-28 |
| ES2183434T3 (es) | 2003-03-16 |
| AU749097B2 (en) | 2002-06-20 |
| RU2223269C2 (ru) | 2004-02-10 |
| TR200001927T2 (tr) | 2001-06-21 |
| NZ505200A (en) | 2002-09-27 |
| CA2316971A1 (en) | 1999-07-01 |
| HUP0004565A3 (en) | 2002-12-28 |
| CN1284952A (zh) | 2001-02-21 |
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