PT3216784T - Processo para a preparação de moduladores do recetor h3 de histamina - Google Patents

Processo para a preparação de moduladores do recetor h3 de histamina

Info

Publication number
PT3216784T
PT3216784T PT17151754T PT17151754T PT3216784T PT 3216784 T PT3216784 T PT 3216784T PT 17151754 T PT17151754 T PT 17151754T PT 17151754 T PT17151754 T PT 17151754T PT 3216784 T PT3216784 T PT 3216784T
Authority
PT
Portugal
Prior art keywords
receptor modulators
histamine
preparing
preparing histamine
modulators
Prior art date
Application number
PT17151754T
Other languages
English (en)
Inventor
Broggini Diego
Lellek Vit
S Mani Neelakandha
Lochner Susanne
Mauer Adrian
J Pippel Daniel
Young Lana
Original Assignee
Janssen Pharmaceutica Nv
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Janssen Pharmaceutica Nv filed Critical Janssen Pharmaceutica Nv
Publication of PT3216784T publication Critical patent/PT3216784T/pt

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D213/00Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/78Carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D213/81Amides; Imides
    • C07D213/82Amides; Imides in position 3
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D405/00Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/12Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07BGENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B2200/00Indexing scheme relating to specific properties of organic compounds
    • C07B2200/13Crystalline forms, e.g. polymorphs

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Medicines Containing Plant Substances (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
PT17151754T 2009-03-18 2010-03-17 Processo para a preparação de moduladores do recetor h3 de histamina PT3216784T (pt)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US16117709P 2009-03-18 2009-03-18

Publications (1)

Publication Number Publication Date
PT3216784T true PT3216784T (pt) 2019-04-01

Family

ID=42315639

Family Applications (2)

Application Number Title Priority Date Filing Date
PT107224495T PT2429996T (pt) 2009-03-18 2010-03-17 Processo para a preparação de moduladores do recetor h3 de histamina
PT17151754T PT3216784T (pt) 2009-03-18 2010-03-17 Processo para a preparação de moduladores do recetor h3 de histamina

Family Applications Before (1)

Application Number Title Priority Date Filing Date
PT107224495T PT2429996T (pt) 2009-03-18 2010-03-17 Processo para a preparação de moduladores do recetor h3 de histamina

Country Status (19)

Country Link
US (4) US8748596B2 (pt)
EP (3) EP2429996B1 (pt)
JP (1) JP5642149B2 (pt)
CN (1) CN102428070B (pt)
AU (1) AU2010226711B2 (pt)
CA (2) CA2755335C (pt)
CY (2) CY1119437T1 (pt)
DK (2) DK2429996T3 (pt)
ES (2) ES2714852T3 (pt)
HR (2) HRP20170776T1 (pt)
HU (2) HUE044837T2 (pt)
LT (2) LT3216784T (pt)
MX (3) MX2011009784A (pt)
PL (2) PL3216784T3 (pt)
PT (2) PT2429996T (pt)
SI (2) SI2429996T1 (pt)
SM (2) SMT201700314T1 (pt)
TR (1) TR201902858T4 (pt)
WO (1) WO2010107897A2 (pt)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK2429996T3 (en) 2009-03-18 2017-06-19 Janssen Pharmaceutica Nv Process for the preparation of histamine h3 receptor modulators
KR101427221B1 (ko) * 2012-08-29 2014-08-13 주식회사 에스텍파마 플루복사민 자유 염기의 정제방법 및 이를 이용한 고순도 플루복사민 말레이트의 제조방법
CN104447867B (zh) * 2013-09-17 2017-12-26 江苏天士力帝益药业有限公司 一种噻吩并哌啶衍生物、制备方法及其应用
MX2022009507A (es) * 2020-02-06 2022-11-09 London Pharmaceuticals And Res Corporation Ésteres de sulfato de cannabinoides, sus sales y usos de los mismos.

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5724346B2 (pt) * 1973-06-22 1982-05-24
EP1558595B1 (en) * 2002-10-23 2009-11-25 Janssen Pharmaceutica N.V. Piperazinyl and diazapanyl benzamides and benzthioamides
WO2007143422A2 (en) 2006-05-30 2007-12-13 Janssen Pharmaceutica N.V. Substituted pyridyl amide compounds as modulators of the histamine h3 receptor
CN101868454A (zh) 2007-11-20 2010-10-20 詹森药业有限公司 作为组胺h3受体调节剂的环烷基氧基吡啶化合物和杂环烷基氧基吡啶化合物
DK2429996T3 (en) 2009-03-18 2017-06-19 Janssen Pharmaceutica Nv Process for the preparation of histamine h3 receptor modulators

Also Published As

Publication number Publication date
LT3216784T (lt) 2019-03-25
EP3216784A1 (en) 2017-09-13
PT2429996T (pt) 2017-06-12
HRP20190476T1 (hr) 2019-05-03
MX2011009784A (es) 2011-09-30
WO2010107897A2 (en) 2010-09-23
US9809547B2 (en) 2017-11-07
CA2755335A1 (en) 2010-09-23
LT2429996T (lt) 2017-06-12
EP2429996B1 (en) 2017-03-08
WO2010107897A3 (en) 2011-04-14
SMT201900217T1 (it) 2019-07-11
CA2755335C (en) 2018-09-18
CA2965059C (en) 2020-04-28
US20120029189A1 (en) 2012-02-02
MX349489B (es) 2017-07-31
JP2012520889A (ja) 2012-09-10
ES2625261T3 (es) 2017-07-19
HUE032345T2 (en) 2017-09-28
EP3216784B1 (en) 2018-12-26
PL2429996T3 (pl) 2017-08-31
HRP20170776T1 (hr) 2017-08-11
EP2429996A2 (en) 2012-03-21
CN102428070B (zh) 2015-05-06
TR201902858T4 (tr) 2019-03-21
AU2010226711A1 (en) 2011-10-13
SI2429996T1 (sl) 2017-08-31
EP3492451B1 (en) 2021-11-03
MX347775B (es) 2017-05-11
DK2429996T3 (en) 2017-06-19
US20140343279A1 (en) 2014-11-20
DK3216784T3 (en) 2019-04-08
HUE044837T2 (hu) 2019-11-28
US8748596B2 (en) 2014-06-10
EP3492451A3 (en) 2019-07-31
SI3216784T1 (sl) 2019-05-31
SMT201700314T1 (it) 2017-07-18
AU2010226711B2 (en) 2015-06-18
PL3216784T3 (pl) 2019-07-31
US20170057919A1 (en) 2017-03-02
US10323002B2 (en) 2019-06-18
US20180022704A1 (en) 2018-01-25
CY1121556T1 (el) 2020-05-29
US9518021B2 (en) 2016-12-13
EP3492451A2 (en) 2019-06-05
CN102428070A (zh) 2012-04-25
ES2714852T3 (es) 2019-05-30
JP5642149B2 (ja) 2014-12-17
CA2965059A1 (en) 2010-09-23
CY1119437T1 (el) 2018-03-07

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