PT3364975T - Combinação de trazodona e gabapentina para o tratamento de dor - Google Patents

Combinação de trazodona e gabapentina para o tratamento de dor

Info

Publication number: PT3364975T
Authority: PT; Portugal
Prior art keywords: trazodone; gabapentin; pain; treatment; combination
Prior art date: 2015-10-22

Application number

PT167818160T

Other languages

English (en)

Original Assignee

Acraf

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2015-10-22

Filing date

2016-10-17

Publication date

2021-05-27

2016-10-17 Application filed by Acraf filed Critical Acraf

2021-05-27 Publication of PT3364975T publication Critical patent/PT3364975T/pt

Links

UGJMXCAKCUNAIE-UHFFFAOYSA-N Gabapentin Chemical compound OC(=O)CC1(CN)CCCCC1 UGJMXCAKCUNAIE-UHFFFAOYSA-N 0.000 title 2
229960002870 gabapentin Drugs 0.000 title 1
PHLBKPHSAVXXEF-UHFFFAOYSA-N trazodone Chemical compound ClC1=CC=CC(N2CCN(CCCN3C(N4C=CC=CC4=N3)=O)CC2)=C1 PHLBKPHSAVXXEF-UHFFFAOYSA-N 0.000 title 1
229960003991 trazodone Drugs 0.000 title 1

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/496—Non-condensed piperazines containing further heterocyclic rings, e.g. rifampin, thiothixene or sparfloxacin
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
- A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2300/00—Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 - A61K41/00

Landscapes

Health & Medical Sciences (AREA)
Veterinary Medicine (AREA)
Public Health (AREA)
General Health & Medical Sciences (AREA)
Animal Behavior & Ethology (AREA)
Life Sciences & Earth Sciences (AREA)
Medicinal Chemistry (AREA)
Chemical & Material Sciences (AREA)
Pharmacology & Pharmacy (AREA)
Epidemiology (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Organic Chemistry (AREA)
General Chemical & Material Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
Neurosurgery (AREA)
Neurology (AREA)
Biomedical Technology (AREA)
Bioinformatics & Cheminformatics (AREA)
Engineering & Computer Science (AREA)
Pain & Pain Management (AREA)
Rheumatology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

PT167818160T 2015-10-22 2016-10-17 Combinação de trazodona e gabapentina para o tratamento de dor PT3364975T (pt)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
EP15191024		2015-10-22

Publications (1)

Publication Number	Publication Date
PT3364975T true PT3364975T (pt)	2021-05-27

Family

ID=54345445

Family Applications (2)

Application Number	Title	Priority Date	Filing Date
PT211588256T PT3881845T (pt)	2015-10-22	2016-10-17	Combinação de trazodona e gabapentina para o tratamento de dor
PT167818160T PT3364975T (pt)	2015-10-22	2016-10-17	Combinação de trazodona e gabapentina para o tratamento de dor

Family Applications Before (1)

Application Number	Title	Priority Date	Filing Date
PT211588256T PT3881845T (pt)	2015-10-22	2016-10-17	Combinação de trazodona e gabapentina para o tratamento de dor

Country Status (28)

Country	Link
US (2)	US10786498B2 (pt)
EP (2)	EP3881845B1 (pt)
JP (1)	JP6924184B2 (pt)
KR (1)	KR102691296B1 (pt)
CN (1)	CN108174599B (pt)
AR (1)	AR106415A1 (pt)
AU (1)	AU2016341063B2 (pt)
BR (1)	BR112018007374B1 (pt)
CA (1)	CA2999389C (pt)
CY (1)	CY1124229T1 (pt)
DK (2)	DK3881845T3 (pt)
EA (2)	EA202190626A3 (pt)
ES (2)	ES2879392T3 (pt)
FI (1)	FI3881845T3 (pt)
GE (2)	GEP20207145B (pt)
HR (2)	HRP20250248T1 (pt)
HU (2)	HUE071186T2 (pt)
IL (1)	IL258316B (pt)
LT (2)	LT3881845T (pt)
MD (2)	MD3881845T2 (pt)
MX (1)	MX380433B (pt)
PL (2)	PL3881845T3 (pt)
PT (2)	PT3881845T (pt)
RS (2)	RS66607B1 (pt)
SI (2)	SI3881845T1 (pt)
SM (2)	SMT202500150T1 (pt)
UA (1)	UA122245C2 (pt)
WO (1)	WO2017067870A1 (pt)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
IT201900006602A1 (it) *	2019-05-07	2020-11-07	Acraf	Composizione farmaceutica per il trattamento del dolore neuropatico
EP3907214A1 (en) *	2020-05-04	2021-11-10	Dompe' Farmaceutici S.P.A.	Co-crystal of ketoprofen, lysine and gabapentin, pharmaceutical compositions and their medical use

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
AU2004271796A1 (en) *	2003-09-12	2005-03-24	Warner-Lambert Company Llc	Combination comprising an alpha-2-delta ligand and an SSRI and/or SNRI for treatment of depression and anxiety disorders
NZ545494A (en) *	2003-09-12	2009-10-30	Pfizer	Combinations comprising alpha-2-delta ligands and serotonin / noradrenaline re-uptake inhibitors
US20080096872A1 (en) *	2004-12-22	2008-04-24	Friedman Robert S	Composition for Treatment of Pain Specification
US20120083508A1 (en) *	2006-12-22	2012-04-05	Allergan, Inc.	Alpha-2b receptor agonist and anticonvulsant compositions for treating chronic pain
EP2179015B1 (en) *	2007-07-18	2013-06-05	Dow Global Technologies LLC	Water-glycol hydraulic fluid compositions
WO2009021058A2 (en) *	2007-08-06	2009-02-12	Trinity Labortories, Inc.	Pharmaceutical compositions for treating chronic pain and pain associated with neuropathy
US20100004485A1 (en) *	2008-07-02	2010-01-07	Teva Pharmaceutical Industries Ltd.	Gabapentin enacarbil salts and processes for their preparation
JP5893135B2 (ja)	2011-06-28	2016-03-23	ビボゾーンインコーポレイテッド	多重ターゲッティングの相乗効果を誘発する有効物質の組合せ及びその用途

2016
- 2016-10-17 BR BR112018007374-1A patent/BR112018007374B1/pt active IP Right Grant
- 2016-10-17 ES ES16781816T patent/ES2879392T3/es active Active
- 2016-10-17 LT LTEP21158825.6T patent/LT3881845T/lt unknown
- 2016-10-17 HU HUE21158825A patent/HUE071186T2/hu unknown
- 2016-10-17 CN CN201680059627.1A patent/CN108174599B/zh active Active
- 2016-10-17 MX MX2018004532A patent/MX380433B/es unknown
- 2016-10-17 MD MDE20220430T patent/MD3881845T2/ro unknown
- 2016-10-17 PT PT211588256T patent/PT3881845T/pt unknown
- 2016-10-17 SM SM20250150T patent/SMT202500150T1/it unknown
- 2016-10-17 HU HUE16781816A patent/HUE054653T2/hu unknown
- 2016-10-17 PT PT167818160T patent/PT3364975T/pt unknown
- 2016-10-17 ES ES21158825T patent/ES3015662T3/es active Active
- 2016-10-17 EA EA202190626A patent/EA202190626A3/ru unknown
- 2016-10-17 EP EP21158825.6A patent/EP3881845B1/en active Active
- 2016-10-17 GE GEAP201614778A patent/GEP20207145B/en unknown
- 2016-10-17 EP EP16781816.0A patent/EP3364975B1/en active Active
- 2016-10-17 WO PCT/EP2016/074835 patent/WO2017067870A1/en not_active Ceased
- 2016-10-17 RS RS20250252A patent/RS66607B1/sr unknown
- 2016-10-17 SM SM20210352T patent/SMT202100352T1/it unknown
- 2016-10-17 IL IL258316A patent/IL258316B/en unknown
- 2016-10-17 UA UAA201804930A patent/UA122245C2/uk unknown
- 2016-10-17 MD MDE20180825T patent/MD3364975T2/ro unknown
- 2016-10-17 US US15/767,543 patent/US10786498B2/en active Active
- 2016-10-17 PL PL21158825.6T patent/PL3881845T3/pl unknown
- 2016-10-17 SI SI201631895T patent/SI3881845T1/sl unknown
- 2016-10-17 AU AU2016341063A patent/AU2016341063B2/en active Active
- 2016-10-17 EA EA201890911A patent/EA037838B1/ru unknown
- 2016-10-17 KR KR1020187013499A patent/KR102691296B1/ko active Active
- 2016-10-17 RS RS20210740A patent/RS61989B1/sr unknown
- 2016-10-17 JP JP2018519360A patent/JP6924184B2/ja active Active
- 2016-10-17 LT LTEP16781816.0T patent/LT3364975T/lt unknown
- 2016-10-17 DK DK21158825.6T patent/DK3881845T3/da active
- 2016-10-17 FI FIEP21158825.6T patent/FI3881845T3/fi active
- 2016-10-17 DK DK16781816.0T patent/DK3364975T3/da active
- 2016-10-17 PL PL16781816T patent/PL3364975T3/pl unknown
- 2016-10-17 GE GEAP202014778A patent/GEAP202014778A/en unknown
- 2016-10-17 HR HRP20250248TT patent/HRP20250248T1/hr unknown
- 2016-10-17 HR HRP20210832TT patent/HRP20210832T1/hr unknown
- 2016-10-17 SI SI201631218T patent/SI3364975T1/sl unknown
- 2016-10-17 CA CA2999389A patent/CA2999389C/en active Active
- 2016-10-20 AR ARP160103200A patent/AR106415A1/es unknown
2020
- 2020-04-15 US US16/849,545 patent/US11752147B2/en active Active
2021
- 2021-06-18 CY CY20211100546T patent/CY1124229T1/el unknown

Also Published As

Publication number	Publication date
PL3364975T3 (pl)	2021-11-02
KR102691296B1 (ko)	2024-08-05
US20180296553A1 (en)	2018-10-18
HRP20250248T1 (hr)	2025-04-11
HUE071186T2 (hu)	2025-08-28
ES2879392T3 (es)	2021-11-22
HUE054653T2 (hu)	2021-09-28
EA201890911A1 (ru)	2018-09-28
EA037838B1 (ru)	2021-05-26
GEAP202014778A (en)	2020-03-10
AR106415A1 (es)	2018-01-10
HRP20210832T1 (hr)	2021-08-06
JP6924184B2 (ja)	2021-08-25
BR112018007374A2 (pt)	2018-10-23
EP3881845B1 (en)	2025-01-15
EA202190626A3 (ru)	2021-09-30
FI3881845T3 (fi)	2025-04-08
BR112018007374B1 (pt)	2023-11-28
LT3881845T (lt)	2025-04-25
IL258316B (en)	2022-08-01
PT3881845T (pt)	2025-02-13
EP3364975B1 (en)	2021-04-07
RS61989B1 (sr)	2021-07-30
CA2999389A1 (en)	2017-04-27
MD3364975T2 (ro)	2021-09-30
GEP20207145B (en)	2020-08-25
SMT202500150T1 (it)	2025-05-12
RS66607B1 (sr)	2025-04-30
PL3881845T3 (pl)	2025-05-12
DK3881845T3 (da)	2025-03-24
EP3364975A1 (en)	2018-08-29
CA2999389C (en)	2023-12-19
SI3364975T1 (sl)	2021-08-31
UA122245C2 (uk)	2020-10-12
HK1252359A1 (zh)	2019-05-24
DK3364975T3 (da)	2021-06-21
MX380433B (es)	2025-03-12
AU2016341063B2 (en)	2022-04-14
US11752147B2 (en)	2023-09-12
WO2017067870A1 (en)	2017-04-27
MX2018004532A (es)	2018-09-12
JP2018531259A (ja)	2018-10-25
LT3364975T (lt)	2021-09-10
CN108174599A (zh)	2018-06-15
EP3881845A2 (en)	2021-09-22
SMT202100352T1 (it)	2021-07-12
MD3881845T2 (ro)	2025-06-30
SI3881845T1 (sl)	2025-05-30
US10786498B2 (en)	2020-09-29
KR20180063314A (ko)	2018-06-11
CY1124229T1 (el)	2022-05-27
EP3881845A3 (en)	2021-09-29
AU2016341063A1 (en)	2018-04-26
IL258316A (en)	2018-06-28
US20200316060A1 (en)	2020-10-08
EA202190626A2 (ru)	2021-06-30
ES3015662T3 (en)	2025-05-07
CN108174599B (zh)	2021-09-03

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