DK3364975T3 - Kombination af trazodon og gabapentin til behandling af smerter - Google Patents

Kombination af trazodon og gabapentin til behandling af smerter Download PDF

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Publication number
DK3364975T3
DK3364975T3 DK16781816.0T DK16781816T DK3364975T3 DK 3364975 T3 DK3364975 T3 DK 3364975T3 DK 16781816 T DK16781816 T DK 16781816T DK 3364975 T3 DK3364975 T3 DK 3364975T3
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DK
Denmark
Prior art keywords
trazodone
gabapentin
pain
treatment
combination
Prior art date
Application number
DK16781816.0T
Other languages
English (en)
Inventor
Beatrice Garrone
Lucia Durando
Fabrizio Calisti
Original Assignee
Acraf
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Acraf filed Critical Acraf
Application granted granted Critical
Publication of DK3364975T3 publication Critical patent/DK3364975T3/da

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Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/496Non-condensed piperazines containing further heterocyclic rings, e.g. rifampin, thiothixene or sparfloxacin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/185Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19Carboxylic acids, e.g. valproic acid
    • A61K31/195Carboxylic acids, e.g. valproic acid having an amino group
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/02Drugs for disorders of the nervous system for peripheral neuropathies
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/04Centrally acting analgesics, e.g. opioids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2300/00Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 - A61K41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
DK16781816.0T 2015-10-22 2016-10-17 Kombination af trazodon og gabapentin til behandling af smerter DK3364975T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP15191024 2015-10-22
PCT/EP2016/074835 WO2017067870A1 (en) 2015-10-22 2016-10-17 Combination of trazodone and gabapentin for the treatment of pain

Publications (1)

Publication Number Publication Date
DK3364975T3 true DK3364975T3 (da) 2021-06-21

Family

ID=54345445

Family Applications (2)

Application Number Title Priority Date Filing Date
DK21158825.6T DK3881845T3 (da) 2015-10-22 2016-10-17 Kombination af trazodon og gabapentin til smertebehandling
DK16781816.0T DK3364975T3 (da) 2015-10-22 2016-10-17 Kombination af trazodon og gabapentin til behandling af smerter

Family Applications Before (1)

Application Number Title Priority Date Filing Date
DK21158825.6T DK3881845T3 (da) 2015-10-22 2016-10-17 Kombination af trazodon og gabapentin til smertebehandling

Country Status (28)

Country Link
US (2) US10786498B2 (da)
EP (2) EP3881845B1 (da)
JP (1) JP6924184B2 (da)
KR (1) KR102691296B1 (da)
CN (1) CN108174599B (da)
AR (1) AR106415A1 (da)
AU (1) AU2016341063B2 (da)
BR (1) BR112018007374B1 (da)
CA (1) CA2999389C (da)
CY (1) CY1124229T1 (da)
DK (2) DK3881845T3 (da)
EA (2) EA202190626A3 (da)
ES (2) ES2879392T3 (da)
FI (1) FI3881845T3 (da)
GE (2) GEP20207145B (da)
HR (2) HRP20250248T1 (da)
HU (2) HUE071186T2 (da)
IL (1) IL258316B (da)
LT (2) LT3881845T (da)
MD (2) MD3881845T2 (da)
MX (1) MX380433B (da)
PL (2) PL3881845T3 (da)
PT (2) PT3881845T (da)
RS (2) RS66607B1 (da)
SI (2) SI3881845T1 (da)
SM (2) SMT202500150T1 (da)
UA (1) UA122245C2 (da)
WO (1) WO2017067870A1 (da)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT201900006602A1 (it) * 2019-05-07 2020-11-07 Acraf Composizione farmaceutica per il trattamento del dolore neuropatico
EP3907214A1 (en) * 2020-05-04 2021-11-10 Dompe' Farmaceutici S.P.A. Co-crystal of ketoprofen, lysine and gabapentin, pharmaceutical compositions and their medical use

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2004271796A1 (en) * 2003-09-12 2005-03-24 Warner-Lambert Company Llc Combination comprising an alpha-2-delta ligand and an SSRI and/or SNRI for treatment of depression and anxiety disorders
NZ545494A (en) * 2003-09-12 2009-10-30 Pfizer Combinations comprising alpha-2-delta ligands and serotonin / noradrenaline re-uptake inhibitors
US20080096872A1 (en) * 2004-12-22 2008-04-24 Friedman Robert S Composition for Treatment of Pain Specification
US20120083508A1 (en) * 2006-12-22 2012-04-05 Allergan, Inc. Alpha-2b receptor agonist and anticonvulsant compositions for treating chronic pain
EP2179015B1 (en) * 2007-07-18 2013-06-05 Dow Global Technologies LLC Water-glycol hydraulic fluid compositions
WO2009021058A2 (en) * 2007-08-06 2009-02-12 Trinity Labortories, Inc. Pharmaceutical compositions for treating chronic pain and pain associated with neuropathy
US20100004485A1 (en) * 2008-07-02 2010-01-07 Teva Pharmaceutical Industries Ltd. Gabapentin enacarbil salts and processes for their preparation
JP5893135B2 (ja) 2011-06-28 2016-03-23 ビボゾーン インコーポレイテッド 多重ターゲッティングの相乗効果を誘発する有効物質の組合せ及びその用途

Also Published As

Publication number Publication date
PL3364975T3 (pl) 2021-11-02
KR102691296B1 (ko) 2024-08-05
US20180296553A1 (en) 2018-10-18
HRP20250248T1 (hr) 2025-04-11
HUE071186T2 (hu) 2025-08-28
ES2879392T3 (es) 2021-11-22
HUE054653T2 (hu) 2021-09-28
EA201890911A1 (ru) 2018-09-28
EA037838B1 (ru) 2021-05-26
GEAP202014778A (en) 2020-03-10
AR106415A1 (es) 2018-01-10
HRP20210832T1 (hr) 2021-08-06
JP6924184B2 (ja) 2021-08-25
BR112018007374A2 (pt) 2018-10-23
EP3881845B1 (en) 2025-01-15
EA202190626A3 (ru) 2021-09-30
FI3881845T3 (fi) 2025-04-08
BR112018007374B1 (pt) 2023-11-28
LT3881845T (lt) 2025-04-25
IL258316B (en) 2022-08-01
PT3881845T (pt) 2025-02-13
EP3364975B1 (en) 2021-04-07
RS61989B1 (sr) 2021-07-30
CA2999389A1 (en) 2017-04-27
MD3364975T2 (ro) 2021-09-30
GEP20207145B (en) 2020-08-25
SMT202500150T1 (it) 2025-05-12
RS66607B1 (sr) 2025-04-30
PL3881845T3 (pl) 2025-05-12
PT3364975T (pt) 2021-05-27
DK3881845T3 (da) 2025-03-24
EP3364975A1 (en) 2018-08-29
CA2999389C (en) 2023-12-19
SI3364975T1 (sl) 2021-08-31
UA122245C2 (uk) 2020-10-12
HK1252359A1 (zh) 2019-05-24
MX380433B (es) 2025-03-12
AU2016341063B2 (en) 2022-04-14
US11752147B2 (en) 2023-09-12
WO2017067870A1 (en) 2017-04-27
MX2018004532A (es) 2018-09-12
JP2018531259A (ja) 2018-10-25
LT3364975T (lt) 2021-09-10
CN108174599A (zh) 2018-06-15
EP3881845A2 (en) 2021-09-22
SMT202100352T1 (it) 2021-07-12
MD3881845T2 (ro) 2025-06-30
SI3881845T1 (sl) 2025-05-30
US10786498B2 (en) 2020-09-29
KR20180063314A (ko) 2018-06-11
CY1124229T1 (el) 2022-05-27
EP3881845A3 (en) 2021-09-29
AU2016341063A1 (en) 2018-04-26
IL258316A (en) 2018-06-28
US20200316060A1 (en) 2020-10-08
EA202190626A2 (ru) 2021-06-30
ES3015662T3 (en) 2025-05-07
CN108174599B (zh) 2021-09-03

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