PT523976E - MANIPULACAO DO NúMERO DE CóPIAS DE GENES EM BORDETELLA - Google Patents

MANIPULACAO DO NúMERO DE CóPIAS DE GENES EM BORDETELLA

Info

Publication number
PT523976E
PT523976E PT92306474T PT92306474T PT523976E PT 523976 E PT523976 E PT 523976E PT 92306474 T PT92306474 T PT 92306474T PT 92306474 T PT92306474 T PT 92306474T PT 523976 E PT523976 E PT 523976E
Authority
PT
Portugal
Prior art keywords
bordetella
natural
strain
genes
gene
Prior art date
Application number
PT92306474T
Other languages
English (en)
Inventor
Sheena Loosmore
Gavin Zealey
Reza Yacoob
Michel Klein
Original Assignee
Aventis Pasteur
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Aventis Pasteur filed Critical Aventis Pasteur
Publication of PT523976E publication Critical patent/PT523976E/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • C07K14/235—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Bordetella (G)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/02—Bacterial antigens
    • A61K39/099—Bordetella
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
    • A61K2039/52—Bacterial cells; Fungal cells; Protozoal cells
    • A61K2039/521—Bacterial cells; Fungal cells; Protozoal cells inactivated (killed)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Biochemistry (AREA)
  • Immunology (AREA)
  • Mycology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Microbiology (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Epidemiology (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
PT92306474T 1991-07-16 1992-07-15 MANIPULACAO DO NúMERO DE CóPIAS DE GENES EM BORDETELLA PT523976E (pt)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB919115332A GB9115332D0 (en) 1991-07-16 1991-07-16 Manipulation of gene copy number in bordetella

Publications (1)

Publication Number Publication Date
PT523976E true PT523976E (pt) 2002-05-31

Family

ID=10698434

Family Applications (1)

Application Number Title Priority Date Filing Date
PT92306474T PT523976E (pt) 1991-07-16 1992-07-15 MANIPULACAO DO NúMERO DE CóPIAS DE GENES EM BORDETELLA

Country Status (10)

Country Link
US (2) US5439810A (pt)
EP (2) EP0523976B1 (pt)
JP (2) JP2602600B2 (pt)
AT (1) ATE209681T1 (pt)
CA (1) CA2073288C (pt)
DE (1) DE69232231T2 (pt)
DK (1) DK0523976T3 (pt)
ES (1) ES2170053T3 (pt)
GB (1) GB9115332D0 (pt)
PT (1) PT523976E (pt)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5786189A (en) * 1989-11-29 1998-07-28 Smithkline Beecham Biologicals (S.A.) Vaccine
US6197548B1 (en) 1990-04-02 2001-03-06 Medeva Pharma Limited Transformed Pichia expressing the pertactin antigen
US5643753A (en) * 1990-04-18 1997-07-01 Connaught Laboratories Limited Use of autologous promoters to express gene products in bordetella
FR2728170A1 (fr) * 1994-12-15 1996-06-21 Pasteur Institut Vaccin de type acellulaire anti-bordetella
US5932714A (en) * 1995-02-23 1999-08-03 Connaught Laboratories Limited Expression of gene products from genetically manipulated strains of Bordetella
US5998168A (en) * 1995-06-07 1999-12-07 Connaught Laboratories Limited Expression of gene products from genetically manipulated strains of bordetella
EP1766002B1 (en) 2004-06-21 2015-11-18 Novozymes A/S Stably maintained multiple copies of at least two orf in the same orientation
EP3800244A1 (en) 2006-03-10 2021-04-07 Institut Pasteur de Lille Live attenuated bordetella strains as a single dose vaccine against whooping cough
RU2445364C2 (ru) * 2006-04-17 2012-03-20 Шеринг-Плоу Лтд. Рекомбинантные аттенуированные микроорганизмы clostridium и вакцина
CA2759280C (en) 2009-04-28 2016-09-20 Inserm (Institut National De La Sante Et De La Recherche Medicale) Vaccine for prophylaxis or treatment of an allergen-driven airway pathology
JP5966018B2 (ja) 2011-12-21 2016-08-10 バイオネット−エイジア，カンパニー・リミテッド 改変ボルデテラ・パータシス株
EP2722338A1 (en) * 2012-10-17 2014-04-23 INSERM (Institut National de la Santé et de la Recherche Médicale) Novel recombinant Bordetella strains
CN109069535B (zh) * 2016-03-29 2022-03-18 里尔巴斯德研究所 突变型博德特氏菌属菌株及其使用方法
CA3077428A1 (en) 2017-10-18 2019-04-25 Institut Pasteur De Lille Bordetella strains expressing serotype 3 fimbriae
EP4247397A4 (en) 2020-11-17 2024-11-06 Iliad Biotechnologies, LLC TREATMENT AND PREVENTION OF NEUROPATHOLOGY ASSOCIATED WITH NEURODEGENERATIVE DISEASES

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8727489D0 (en) * 1987-11-24 1987-12-23 Connaught Lab Detoxification of pertussis toxin
GB8807860D0 (en) * 1988-04-05 1988-05-05 Connaught Lab Pertussis vaccine
ES2078258T3 (es) * 1989-04-28 1995-12-16 Sclavo Spa Mutantes de toxina pertussica, cepas de bordetella capaces de producir tales mutantes y su uso en el desarrollo de vacunas antipertussicas.
GB9008746D0 (en) * 1990-04-18 1990-06-13 Connaught Lab The use of autologous promoters to express gene products in bordetella
EP0485701A1 (en) * 1990-09-28 1992-05-20 American Cyanamid Company Insertion of DNA by modified transposons

Also Published As

Publication number Publication date
EP0523976A3 (en) 1993-11-10
DK0523976T3 (da) 2002-04-02
CA2073288C (en) 1999-12-07
DE69232231D1 (de) 2002-01-10
JPH07184643A (ja) 1995-07-25
DE69232231T2 (de) 2002-05-23
JP3070031B2 (ja) 2000-07-24
EP0523976B1 (en) 2001-11-28
CA2073288A1 (en) 1993-01-17
JP2602600B2 (ja) 1997-04-23
GB9115332D0 (en) 1991-08-28
EP1184459A2 (en) 2002-03-06
EP1184459A3 (en) 2004-05-12
US5439810A (en) 1995-08-08
ES2170053T3 (es) 2002-08-01
ATE209681T1 (de) 2001-12-15
US5849530A (en) 1998-12-15
EP0523976A2 (en) 1993-01-20
JPH05317039A (ja) 1993-12-03

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