DK0523976T3 - Manipulering af genkopital i Bordetella - Google Patents

Manipulering af genkopital i Bordetella

Info

Publication number
DK0523976T3
DK0523976T3 DK92306474T DK92306474T DK0523976T3 DK 0523976 T3 DK0523976 T3 DK 0523976T3 DK 92306474 T DK92306474 T DK 92306474T DK 92306474 T DK92306474 T DK 92306474T DK 0523976 T3 DK0523976 T3 DK 0523976T3
Authority
DK
Denmark
Prior art keywords
bordetella
natural
strain
gene
genes
Prior art date
Application number
DK92306474T
Other languages
English (en)
Inventor
Sheena Loosmore
Gavin Zealey
Reza Yacoob
Michel Klein
Original Assignee
Aventis Pasteur
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Aventis Pasteur filed Critical Aventis Pasteur
Application granted granted Critical
Publication of DK0523976T3 publication Critical patent/DK0523976T3/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • C07K14/235—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Bordetella (G)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/02—Bacterial antigens
    • A61K39/099—Bordetella
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
    • A61K2039/52—Bacterial cells; Fungal cells; Protozoal cells
    • A61K2039/521—Bacterial cells; Fungal cells; Protozoal cells inactivated (killed)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Mycology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Immunology (AREA)
  • Microbiology (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Epidemiology (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
DK92306474T 1991-07-16 1992-07-15 Manipulering af genkopital i Bordetella DK0523976T3 (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB919115332A GB9115332D0 (en) 1991-07-16 1991-07-16 Manipulation of gene copy number in bordetella

Publications (1)

Publication Number Publication Date
DK0523976T3 true DK0523976T3 (da) 2002-04-02

Family

ID=10698434

Family Applications (1)

Application Number Title Priority Date Filing Date
DK92306474T DK0523976T3 (da) 1991-07-16 1992-07-15 Manipulering af genkopital i Bordetella

Country Status (10)

Country Link
US (2) US5439810A (da)
EP (2) EP0523976B1 (da)
JP (2) JP2602600B2 (da)
AT (1) ATE209681T1 (da)
CA (1) CA2073288C (da)
DE (1) DE69232231T2 (da)
DK (1) DK0523976T3 (da)
ES (1) ES2170053T3 (da)
GB (1) GB9115332D0 (da)
PT (1) PT523976E (da)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5786189A (en) * 1989-11-29 1998-07-28 Smithkline Beecham Biologicals (S.A.) Vaccine
US6197548B1 (en) 1990-04-02 2001-03-06 Medeva Pharma Limited Transformed Pichia expressing the pertactin antigen
US5643753A (en) * 1990-04-18 1997-07-01 Connaught Laboratories Limited Use of autologous promoters to express gene products in bordetella
FR2728170A1 (fr) * 1994-12-15 1996-06-21 Pasteur Institut Vaccin de type acellulaire anti-bordetella
US5932714A (en) * 1995-02-23 1999-08-03 Connaught Laboratories Limited Expression of gene products from genetically manipulated strains of Bordetella
US5998168A (en) * 1995-06-07 1999-12-07 Connaught Laboratories Limited Expression of gene products from genetically manipulated strains of bordetella
CN101006174B (zh) * 2004-06-21 2010-05-26 诺维信公司 以相同取向稳定保持的至少两个orf的多拷贝
CA2645190C (en) 2006-03-10 2019-01-15 Institut Pasteur De Lille Live attenuated bordetella strains as a single dose vaccine against whooping cough
KR20080110908A (ko) * 2006-04-17 2008-12-19 쉐링-프라우 리미티드 재조합의 약독화된 클로스트리듐 유기체 및 백신
CN102448490B (zh) 2009-04-28 2015-05-13 国家健康与医学研究院 用于预防或治疗过敏原引起的气道疾病的疫苗
IN2014CN04700A (da) 2011-12-21 2015-09-18 Bionet Asia Co Ltd
EP2722338A1 (en) * 2012-10-17 2014-04-23 INSERM (Institut National de la Santé et de la Recherche Médicale) Novel recombinant Bordetella strains
FI3436034T3 (fi) * 2016-03-29 2025-05-08 Pasteur Institut Mutantteja bordetella-kantoja ja käyttömenetelmiä
CA3077428A1 (en) 2017-10-18 2019-04-25 Institut Pasteur De Lille Bordetella strains expressing serotype 3 fimbriae
AU2021385036A1 (en) 2020-11-17 2023-06-08 ILiAD Biotechnologies, Inc. Treatment and prevention of neuropathology associated with neurodegenerative diseases

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8727489D0 (en) * 1987-11-24 1987-12-23 Connaught Lab Detoxification of pertussis toxin
GB8807860D0 (en) * 1988-04-05 1988-05-05 Connaught Lab Pertussis vaccine
ATE127347T1 (de) * 1989-04-28 1995-09-15 Sclavo Spa Pertussistoxin-mutanten, dieselbe produzierende bordetella-stämme und ihre verwendung als vakzin gegen pertussis.
GB9008746D0 (en) * 1990-04-18 1990-06-13 Connaught Lab The use of autologous promoters to express gene products in bordetella
EP0485701A1 (en) * 1990-09-28 1992-05-20 American Cyanamid Company Insertion of DNA by modified transposons

Also Published As

Publication number Publication date
DE69232231T2 (de) 2002-05-23
CA2073288A1 (en) 1993-01-17
US5849530A (en) 1998-12-15
EP0523976B1 (en) 2001-11-28
EP0523976A3 (en) 1993-11-10
US5439810A (en) 1995-08-08
JPH05317039A (ja) 1993-12-03
ES2170053T3 (es) 2002-08-01
EP1184459A3 (en) 2004-05-12
GB9115332D0 (en) 1991-08-28
CA2073288C (en) 1999-12-07
PT523976E (pt) 2002-05-31
JP3070031B2 (ja) 2000-07-24
JP2602600B2 (ja) 1997-04-23
EP1184459A2 (en) 2002-03-06
DE69232231D1 (de) 2002-01-10
JPH07184643A (ja) 1995-07-25
EP0523976A2 (en) 1993-01-20
ATE209681T1 (de) 2001-12-15

Similar Documents

Publication Publication Date Title
PT523976E (pt) MANIPULACAO DO NúMERO DE CóPIAS DE GENES EM BORDETELLA
Niesert et al. Origin of life between Scylla and Charybdis
ATE141517T1 (de) Gen-sequenzentransfer und -exprimierung bei zellen des zentralen nervensystems mit mutierenden herpes-simplex-viren, die deletionen in viren-replikationsgenen enthalten
ATE169061T1 (de) Methode des gentransfers mittels retrotransposons
DK0637335T3 (da) Rekombinante mutanter til induktion af specifikke immunreaktioner
PL365456A1 (en) Regulated antigen delivery system (rads)
GR3019238T3 (en) Genetic detoxification of pertussis toxin
ES2104626T3 (es) Secuencia de adn que comprende un gen codante para la reductasa de xilosa o la reductasa de xilosa y la deshidrogenasa de xilitol.
ATE103331T1 (de) Vakzine.
ATE443762T1 (de) Induktierbare transposition beim transgenen organismus mit transposon-vektor
Alfimova et al. Psychogenetics of aggression
EP0540135A3 (en) Attenuated measles vaccine virus strain containing specific nucleotide sequence and a method for its absolute identification
DE69629819D1 (de) Avirulente herpetische viren verwendbar als tumorzerstörendes agens und impfstoff
ATE485378T1 (de) 1,3-propanediol dehydrogenase mutant
YU200091A (sh) Delecioni mutanti ahasarezistentni na herbicide
DE69012784D1 (de) Transformiertes Shigella.
Loosmore et al. Manipulation of gene copy number in Bordetella
GT200000138A (es) Gen de streptomyces avermitilis que dirige la relacion de avermectinas b2 : b1 (1).
ATE279944T1 (de) Kombinationsimpfstoff zur steigerung der immunität gegen brucellose
DK0426059T3 (da) Promotorområder for generne der koder pilinunderenhederne fim2, fim3 og fimx af Bordetella pertussis, samt anvendelse deraf til ekspression af gener, der koder for et ønsket protein
ES2148160T3 (es) Gen codante para una esterasa y microorganismo que contiene este gen.
Huang Ecology of Co-Circulating Pathogens in a Demographic Transitioning Host Population
WO2002029063A1 (en) Novel recombinant feline herpesvirus 1 and polyvalent vaccine with the use of the same
Dean The effect of learning on the" influence of chance, history, and adaptation" in artificial evolution
Chun Two novel genes of Bradyrhizobium japonicum involved in nodule formation and function