PT656014E - Proteina rib, uma proteina da superficie celular que confere imunidade a muitas estirpes de estreptococos do grupo b: processo para purificacao da proteina, estojo de reagentes e composicao farmaceutica - Google Patents

Proteina rib, uma proteina da superficie celular que confere imunidade a muitas estirpes de estreptococos do grupo b: processo para purificacao da proteina, estojo de reagentes e composicao farmaceutica

Info

Publication number
PT656014E
PT656014E PT94911348T PT94911348T PT656014E PT 656014 E PT656014 E PT 656014E PT 94911348 T PT94911348 T PT 94911348T PT 94911348 T PT94911348 T PT 94911348T PT 656014 E PT656014 E PT 656014E
Authority
PT
Portugal
Prior art keywords
protein
purification
pharmaceutical composition
streptopes
estreptococks
Prior art date
Application number
PT94911348T
Other languages
English (en)
Inventor
Gunnar Lindahl
Margareth Stalhammar-Carlemalm
Lars Stenberg
Original Assignee
Gunnar Lindahl
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Gunnar Lindahl filed Critical Gunnar Lindahl
Publication of PT656014E publication Critical patent/PT656014E/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • C07K14/315—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Streptococcus (G), e.g. Enterococci
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/02—Bacterial antigens
    • A61K39/09—Lactobacillales, e.g. aerococcus, enterococcus, lactobacillus, lactococcus, streptococcus
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S530/00—Chemistry: natural resins or derivatives; peptides or proteins; lignins or reaction products thereof
    • Y10S530/82—Proteins from microorganisms
    • Y10S530/825—Bacteria

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Immunology (AREA)
  • Biochemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Biomedical Technology (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Microbiology (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Epidemiology (AREA)
  • Oncology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biotechnology (AREA)
  • Cell Biology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Food Science & Technology (AREA)
  • Mycology (AREA)
  • General Physics & Mathematics (AREA)
  • Communicable Diseases (AREA)
  • Pathology (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
PT94911348T 1993-03-19 1994-03-21 Proteina rib, uma proteina da superficie celular que confere imunidade a muitas estirpes de estreptococos do grupo b: processo para purificacao da proteina, estojo de reagentes e composicao farmaceutica PT656014E (pt)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
SE9300234 1993-03-19

Publications (1)

Publication Number Publication Date
PT656014E true PT656014E (pt) 2003-09-30

Family

ID=20388669

Family Applications (1)

Application Number Title Priority Date Filing Date
PT94911348T PT656014E (pt) 1993-03-19 1994-03-21 Proteina rib, uma proteina da superficie celular que confere imunidade a muitas estirpes de estreptococos do grupo b: processo para purificacao da proteina, estojo de reagentes e composicao farmaceutica

Country Status (17)

Country Link
US (1) US5869064A (pt)
EP (1) EP0656014B1 (pt)
JP (1) JP3976334B2 (pt)
KR (1) KR100331358B1 (pt)
CN (1) CN1046291C (pt)
AT (1) ATE240351T1 (pt)
CA (1) CA2158658A1 (pt)
DE (1) DE69432658T2 (pt)
DK (1) DK0656014T3 (pt)
ES (1) ES2194024T3 (pt)
HU (1) HU217582B (pt)
NZ (1) NZ263275A (pt)
PT (1) PT656014E (pt)
SG (1) SG47049A1 (pt)
SI (1) SI0656014T1 (pt)
WO (1) WO1994021685A1 (pt)
ZA (1) ZA941958B (pt)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6015889A (en) * 1993-03-19 2000-01-18 Gunnar Lindahl Protein rib, a cell surface protein that confers immunity to many strains of the group B streptococcus: process for purification of the protein, reagent kit and pharmaceutical composition
ATE347600T1 (de) 1998-02-20 2006-12-15 Id Biomedical Corp Gruppe b-streptococcus antigene
US6890539B2 (en) 1998-12-22 2005-05-10 Microscience, Ltd. Genes and proteins, and their use
ES2281977T3 (es) * 1998-12-22 2007-10-01 Microscience Limited Proteinas de estreptococo del grupo b y su utilizacion.
AU758722B2 (en) * 1998-12-22 2003-03-27 Microscience Limited Outer surface proteins, their genes, and their use
US7128918B1 (en) 1998-12-23 2006-10-31 Id Biomedical Corporation Streptococcus antigens
PL205041B1 (pl) * 1998-12-23 2010-03-31 Id Biomedical Corp Izolowany polinukleotyd, wektor zawierający izolowany polinukleotyd, komórka gospodarza transfekowana lub transformowana za pomocą tego wektora, sposób wytwarzania polipeptydu kodowanego przez izolowany polinukleotyd, izolowany polipeptyd, chimeryczny polipeptyd, kompozycja do szczepionek zawierająca polipeptyd oraz jej zastosowanie w leczeniu lub zapobieganiu zakażeniu osobnika paciorkowcem
GB9910375D0 (en) 1999-05-05 1999-06-30 Lindahl Gunnar Vaccine composition
JP3934605B2 (ja) * 2001-05-31 2007-06-20 扶桑薬品工業株式会社 感染症原因微生物の検出および同定のための改良された方法
CA2447775A1 (en) * 2001-05-31 2002-12-19 Fuso Pharmaceutical Industries, Ltd. Process for evaluating phagocytotic function and use thereof
EP1472353B1 (en) * 2002-02-11 2012-02-01 ID Biomedical Corporation Group b streptococcus antigen
CA2597170A1 (en) * 2005-02-08 2006-08-17 Id Biomedical Corporation Of Quebec C.O.B. As Glaxosmithkline Biological S North America Pharmaceutical compositions
PT2144924T (pt) * 2007-04-16 2016-08-17 Minervax Aps Vacina de proteína de fusão
CA3001433A1 (en) 2015-10-21 2017-04-27 Minervax Aps Immunogenic fusion protein
WO2017114655A1 (en) 2015-12-30 2017-07-06 Minervax Aps Immunogenic complex for eliciting protective immunity against group b streptococcus
EP3638301A1 (en) 2017-06-16 2020-04-22 GlaxoSmithKline Biologicals S.A. Method of treatment
BR112022008761A2 (pt) 2019-11-22 2022-07-26 Glaxosmithkline Biologicals Sa Dosagem e administração de uma vacina de glicoconjugado de sacarídeo
EP4066854A1 (en) 2021-03-29 2022-10-05 MinervaX Immunogenic fusion protein
EP4748391A1 (en) 2024-11-20 2026-05-27 MinervaX ApS N-terminal region of a group b streptococcus surface protein as a carrier for the capsular polysaccharide
EP4748392A1 (en) 2024-11-20 2026-05-27 MinervaX ApS Vaccine formulation

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5302386A (en) * 1986-04-16 1994-04-12 Brigham And Women's Hospital, Inc. Bacterial antigens, antibodies, vaccines and methods of manufacture
US4772584A (en) * 1986-05-23 1988-09-20 Cleary Paul P Inhibitor of C5a-mediated chemotaxis
EP0367890A1 (en) * 1988-11-11 1990-05-16 HighTech Receptor AB Protein Arp, with immunoglobulin A binding activity, cloning and expression thereof
US5648241A (en) * 1989-09-15 1997-07-15 The General Hospital Corporation Conjugate vaccine against group B streptococcus
IL95578A (en) * 1989-09-15 1998-08-16 Gen Hospital Corp Conjugate vaccine formed from a polysaccharide and a c protein of b-streptococcus
JPH06506114A (ja) * 1991-03-29 1994-07-14 ファウルマン, エルビン 新規な遺伝子及びIgA結合蛋白質の製造方法

Also Published As

Publication number Publication date
JPH09500092A (ja) 1997-01-07
ES2194024T3 (es) 2003-11-16
KR960701096A (ko) 1996-02-24
HK1008825A1 (en) 1999-05-21
DE69432658D1 (de) 2003-06-18
CN1046291C (zh) 1999-11-10
KR100331358B1 (ko) 2002-08-13
SI0656014T1 (en) 2003-12-31
CA2158658A1 (en) 1994-09-29
EP0656014A1 (en) 1995-06-07
AU6389194A (en) 1994-10-11
ATE240351T1 (de) 2003-05-15
DK0656014T3 (da) 2003-08-11
HUT72841A (en) 1996-05-28
CN1119442A (zh) 1996-03-27
EP0656014B1 (en) 2003-05-14
AU681130B2 (en) 1997-08-21
WO1994021685A1 (en) 1994-09-29
HU9501993D0 (en) 1995-08-28
SG47049A1 (en) 1998-03-20
DE69432658T2 (de) 2004-04-08
JP3976334B2 (ja) 2007-09-19
ZA941958B (en) 1995-01-27
NZ263275A (en) 1997-07-27
US5869064A (en) 1999-02-09
HU217582B (hu) 2000-02-28

Similar Documents

Publication Publication Date Title
ZA941958B (en) Protein rib,a cell surface protein that confers immunity to many strains of the group B steptococcus process for purification of the protein reagent kit and pharmaceutical composition
KR950032279A (ko) 인체의 프로그램된 세포 사멸과 관련 있는 펩티드 및 이를 암호하는 디엔에이(dna)
ES2077666T3 (es) Proteina de union a fibronectina y su preparacion.
BR0112785A (pt) Peptìdeos de promiostatina e métodos de uso dos mesmos
DK0994728T3 (da) Rekombinante antistoffer, som er specifikke for beta-amyloide ender, DNA, der koder derfor, samt fremgangsmåder til anvendelse heraf
BR9814404A (pt) " clonagem de expressão em fungos filamentosos "
ES2068907T3 (es) Secuencias de nucleotidos que codifican una proteina con actividad ureasica.
DE3783191D1 (de) Verfahren und mittel zur herstellung eines proteins mit der gleichen igg-spezifizitaet wie protein g.
FI962247L (fi) Uudet apoptoosia muuntavat proteiinit, niitä koodaava DNA ja näiden käyttömenetelmät
NO944245D0 (no) Rekombinante DNA-molekyler som koder for aminopeptidase-enzymer og deres anvendelse ved fremstilling av vaksiner mot helmintinfeksjoner
CA2192940A1 (en) Nucleotide sequences of pestivirus strains, polypeptides encoded by these sequences and use thereof for diagnosis and prevention of pestivirus infections
NZ500540A (en) Purified proteins, fusion proteins, recombinant vector, vaccine, kit, comprising proteins from Actinobacillus pleuropneumoniae
EP0554389A4 (en) Molecular clones of hiv-1 and uses thereof
SE8505458L (sv) Bakteriofager som igenkennings- och identifieringsmedel
HUP0100668A2 (hu) Virulenciával kapcsolatos nukleinsavszekvenciák és alkalmazásuk
WO1996008569A3 (en) Methods and compositions for identifying streptococcus containing a cysteine protease or fragment thereof
FI972170A7 (fi) Peptidejä, jotka kykenevät sitoutumaan GAP-proteiinin SH3-domeeniin, n äitä peptidejä koodittavia nukleotidisekvenssejä, niiden valmistus ja käyttö
DK0918865T3 (da) Immunologisk aktive proteiner af Borrelia burgdorferi, derfor kodende nukleinsyrer samt deres anvendelse i testkits og som vacciner
BR0011469A (pt) Gm-csf equina
NO922421L (no) Collagenbindende protein, samt fremstilling derav
BR9908476A (pt) Peptìdeo, composição terapêutica, e, processo para conferir imunidade protetora a um paciente, contra a infecção de s. pneumoniae
AR022150A1 (es) Acidos nucleicos derivados de monocitos y composiciones y metodos relacionados
ATE176913T1 (de) Faser-hemagglutinin von b. pertussis
AU4981093A (en) Nucleotide sequences coding for cryptosporidium proteins, polypeptides coded by said sequences and kits for the use thereof
BR9713111A (pt) Processo de duas etapas para a produção de itens moldados de poliuretano semi-rìgido.