PT736009E - N-oxidos de 4-arilpiperazinas e 4-arilpiperidinas como farmacos antipsicoticos - Google Patents

N-oxidos de 4-arilpiperazinas e 4-arilpiperidinas como farmacos antipsicoticos

Info

Publication number: PT736009E
Authority: PT; Portugal
Prior art keywords: arylipypherazines; arylippyridines; oxides; psychotic drugs; psychotic
Prior art date: 1993-12-23

Application number

PT95906100T

Other languages

English (en)

Inventor

Mark E Mcdonnell

Allen B Reitz

Original Assignee

Ortho Pharma Corp

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1993-12-23

Filing date

1994-12-22

Publication date

2003-01-31

1994-12-22 Application filed by Ortho Pharma Corp filed Critical Ortho Pharma Corp

2003-01-31 Publication of PT736009E publication Critical patent/PT736009E/pt

Links

239000000164 antipsychotic agent Substances 0.000 title abstract 2
150000001875 compounds Chemical class 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
- C07D295/22—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with hetero atoms directly attached to ring nitrogen atoms
- C07D295/24—Oxygen atoms
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/92—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with a hetero atom directly attached to the ring nitrogen atom
- C07D211/94—Oxygen atom, e.g. piperidine N-oxide

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
General Chemical & Material Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Neurology (AREA)
Neurosurgery (AREA)
Chemical Kinetics & Catalysis (AREA)
Psychiatry (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Pharmacology & Pharmacy (AREA)
Biomedical Technology (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Hydrogenated Pyridines (AREA)
Plural Heterocyclic Compounds (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)

PT95906100T 1993-12-23 1994-12-22 N-oxidos de 4-arilpiperazinas e 4-arilpiperidinas como farmacos antipsicoticos PT736009E (pt)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
US17338293A	1993-12-23	1993-12-23

Publications (1)

Publication Number	Publication Date
PT736009E true PT736009E (pt)	2003-01-31

Family

ID=22631753

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
PT95906100T PT736009E (pt)	1993-12-23	1994-12-22	N-oxidos de 4-arilpiperazinas e 4-arilpiperidinas como farmacos antipsicoticos

Country Status (16)

Country	Link
EP (1)	EP0736009B1 (pt)
JP (1)	JPH09507077A (pt)
AT (1)	ATE223898T1 (pt)
AU (1)	AU687501B2 (pt)
CA (1)	CA2179735A1 (pt)
DE (1)	DE69431360T2 (pt)
DK (1)	DK0736009T3 (pt)
ES (1)	ES2183862T3 (pt)
IL (1)	IL112099A (pt)
MX (1)	MX9500228A (pt)
NZ (1)	NZ278261A (pt)
PT (1)	PT736009E (pt)
RU (1)	RU2123001C1 (pt)
SI (1)	SI0736009T1 (pt)
WO (1)	WO1995017385A1 (pt)
ZA (1)	ZA9410287B (pt)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
MX9701282A (es) *	1994-08-18	1997-05-31	Pfizer	Fenoles neuroprotectores.
RU2119336C1 (ru) *	1995-12-20	1998-09-27	Валерий Ксенофонтович Смирнов	Способ лечения шизофрении у женщин
USRE46117E1 (en)	1999-12-22	2016-08-23	Teva Pharmaceuticals International Gmbh	Modulators of dopamine neurotransmission
TWI232858B (en) *	2000-08-11	2005-05-21	Ono Pharmaceutical Co	Piperidine derivatives and pharmaceutical compositions containing such derivatives as an effective ingredient
ATE348818T1 (de)	2003-06-12	2007-01-15	Btg Int Ltd	Cyclische hydroxylamine als psychoactive verbindugen
CN101711236B (zh) *	2007-04-12	2012-10-31	Nsab神经研究瑞典公司分公司	表现出改善的心血管副作用特性的多巴胺受体稳定剂/调节剂的n-氧化物和/或二-n-氧化物衍生物
TWI579272B (zh)	2011-12-08	2017-04-21	梯瓦製藥國際有限責任公司	普多比啶（ｐｒｉｄｏｐｉｄｉｎｅ）之氫溴酸鹽
AU2013243461A1 (en)	2012-04-04	2014-11-06	Teva Pharmaceuticals International Gmbh	Pharmaceutical compositions for combination therapy
MX2017008136A (es)	2014-12-22	2018-03-06	Teva Pharmaceuticals Int Gmbh	Sal de l-tartrato de pridopidina.

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
FR2614021B1 (fr) *	1987-04-14	1991-03-01	Andre Buzas	Derives de la 1-((1,1-diphenyl)-1-alcenyl)-piperazine, procede d'obtention et compositions pharmaceutiques les contenant
US4780466A (en) *	1988-03-17	1988-10-25	Hoechst-Roussel Pharmaceuticals, Inc.	Arylpiperazinylalkoxy derivatives of cyclic imides
DK161148C (da) *	1988-06-14	1991-11-18	Novo Nordisk As	Imidazoquinoxalinforbindelser, fremgangsmaade til fremstilling deraf samt farmaceutiske praeprater indeholdende forbindelserne
ES2059602T3 (es) *	1989-04-14	1994-11-16	Merz & Co Gmbh & Co	Uso de derivados de adamantano para la prevencion y tratamiento de isquemia cerebral.
IE914218A1 (en) *	1991-09-11	1993-03-24	Mcneilab Inc	Novel 4-arylpiperazines and 4-arylpiperidines
FR2697251B1 (fr) *	1992-10-22	1994-12-02	Synthelabo	N-oxydes de dérivés de 1-(4-chlorophényl)-2-[4-[(4-fluorophényl)méthyl] pipéridin-1-yl]éthanol, leur procédé de préparation et leur application en thérapeutique.

1994
- 1994-12-21 IL IL11209994A patent/IL112099A/xx not_active IP Right Cessation
- 1994-12-22 SI SI9430427T patent/SI0736009T1/xx unknown
- 1994-12-22 ES ES95906100T patent/ES2183862T3/es not_active Expired - Lifetime
- 1994-12-22 NZ NZ278261A patent/NZ278261A/en unknown
- 1994-12-22 RU RU96115155A patent/RU2123001C1/ru not_active IP Right Cessation
- 1994-12-22 CA CA002179735A patent/CA2179735A1/en not_active Abandoned
- 1994-12-22 JP JP7517623A patent/JPH09507077A/ja not_active Ceased
- 1994-12-22 EP EP95906100A patent/EP0736009B1/en not_active Expired - Lifetime
- 1994-12-22 DK DK95906100T patent/DK0736009T3/da active
- 1994-12-22 AU AU14446/95A patent/AU687501B2/en not_active Ceased
- 1994-12-22 PT PT95906100T patent/PT736009E/pt unknown
- 1994-12-22 WO PCT/US1994/014850 patent/WO1995017385A1/en not_active Ceased
- 1994-12-22 AT AT95906100T patent/ATE223898T1/de not_active IP Right Cessation
- 1994-12-22 DE DE69431360T patent/DE69431360T2/de not_active Expired - Fee Related
- 1994-12-22 ZA ZA9410287A patent/ZA9410287B/xx unknown
1995
- 1995-01-02 MX MX9500228A patent/MX9500228A/es not_active IP Right Cessation

Also Published As

Publication number	Publication date
EP0736009B1 (en)	2002-09-11
MX9500228A (es)	1997-02-28
RU2123001C1 (ru)	1998-12-10
DE69431360D1 (de)	2002-10-17
WO1995017385A1 (en)	1995-06-29
SI0736009T1 (en)	2003-04-30
IL112099A0 (en)	1995-03-15
AU1444695A (en)	1995-07-10
NZ278261A (en)	1998-08-26
DK0736009T3 (da)	2002-10-07
EP0736009A1 (en)	1996-10-09
IL112099A (en)	1999-07-14
DE69431360T2 (de)	2003-01-23
ZA9410287B (en)	1996-06-24
JPH09507077A (ja)	1997-07-15
ATE223898T1 (de)	2002-09-15
AU687501B2 (en)	1998-02-26
ES2183862T3 (es)	2003-04-01
CA2179735A1 (en)	1995-06-29

Publication	Publication Date	Title
MX9102407A (es)	1994-05-31	4 arilpiperazinas y 4-arilpiperidinas novedosas.
AR021811A1 (es)	2002-08-07	Compuestos de piridina fusionados, utiles como inhibidores de gmpc fosfodiesterasa y las composiciones farmaceuticas que las contienen.
DK0582789T3 (da)	2002-01-21	Nye (7-substitueret)-8-(substitueret)-9-(substitueret glycyl)amido-6-demethyl-6-deoxytetracycliner
DE69333062D1 (de)	2003-07-31	4-mercaptoacetylamino-[2]benzazepinon(3)- derivate, und verwendung als enkephalinase-inhibitoren
PT582810E (pt)	2002-08-30	Novas 7-(substituidas)-8-(substituidas)-9-(substituidas)-6-desmetil-6-desoxitetraciclinas como agentes antibioticos
ES2062374T3 (es)	1994-12-16	Heteroarilpiperazinas, agentes antipsicoticos.
ES2195397T3 (es)	2003-12-01	Quinazolin-2,4-dionas sustituidas en posicion 7 utiles como agentes antibacterianos.
ES2136887T3 (es)	1999-12-01	Derivados antifungicos de sordaridina.
ATE203519T1 (de)	2001-08-15	Chinolinderivate als antimalariamittel
NO863790D0 (no)	1986-09-23	Kinolinderivater.
PT736009E (pt)	2003-01-31	N-oxidos de 4-arilpiperazinas e 4-arilpiperidinas como farmacos antipsicoticos
ES2104174T3 (es)	1997-10-01	Derivados de bencilamino, bencilamido y bencilimido ciclicos utilizados como agentes antipsicoticos.