PT78259B - Novel process and product - Google Patents

Novel process and product

Info

Publication number: PT78259B
Authority: PT; Portugal
Prior art keywords: alkanol; chlorthalidone; solution; product; carrier
Prior art date: 1983-03-16

Application number

PT78259A

Other languages

English (en)

Other versions

PT78259A (en

Original Assignee

Boehringer Ingelheim Ltd

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1983-03-16

Filing date

1984-03-15

Publication date

1986-08-08

1984-03-15 Application filed by Boehringer Ingelheim Ltd filed Critical Boehringer Ingelheim Ltd

1984-04-01 Publication of PT78259A publication Critical patent/PT78259A/pt

1986-08-08 Publication of PT78259B publication Critical patent/PT78259B/pt

Links

238000000034 method Methods 0.000 title abstract 2
JIVPVXMEBJLZRO-CQSZACIVSA-N 2-chloro-5-[(1r)-1-hydroxy-3-oxo-2h-isoindol-1-yl]benzenesulfonamide Chemical compound C1=C(Cl)C(S(=O)(=O)N)=CC([C@@]2(O)C3=CC=CC=C3C(=O)N2)=C1 JIVPVXMEBJLZRO-CQSZACIVSA-N 0.000 abstract 3
OKKJLVBELUTLKV-UHFFFAOYSA-N Methanol Chemical compound OC OKKJLVBELUTLKV-UHFFFAOYSA-N 0.000 abstract 3
229960001523 chlortalidone Drugs 0.000 abstract 3
XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 abstract 2
150000005215 alkyl ethers Chemical class 0.000 abstract 1
230000015572 biosynthetic process Effects 0.000 abstract 1
239000006227 byproduct Substances 0.000 abstract 1
239000006185 dispersion Substances 0.000 abstract 1
230000008020 evaporation Effects 0.000 abstract 1
238000001704 evaporation Methods 0.000 abstract 1
229920000036 polyvinylpyrrolidone Polymers 0.000 abstract 1

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/141—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers
- A61K9/146—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers with organic macromolecular compounds
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/167—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction with an outer layer or coating comprising drug; with chemically bound drugs or non-active substances on their surface
- A61K9/1676—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction with an outer layer or coating comprising drug; with chemically bound drugs or non-active substances on their surface having a drug-free core with discrete complete coating layer containing drug
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/10—Antioedematous agents; Diuretics

Landscapes

Health & Medical Sciences (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Veterinary Medicine (AREA)
Life Sciences & Earth Sciences (AREA)
Chemical & Material Sciences (AREA)
Public Health (AREA)
General Health & Medical Sciences (AREA)
Medicinal Chemistry (AREA)
Animal Behavior & Ethology (AREA)
Pharmacology & Pharmacy (AREA)
Epidemiology (AREA)
Organic Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
General Chemical & Material Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
Diabetes (AREA)
Hematology (AREA)
Medicinal Preparation (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Addition Polymer Or Copolymer, Post-Treatments, Or Chemical Modifications (AREA)
Compositions Of Macromolecular Compounds (AREA)
Processes Of Treating Macromolecular Substances (AREA)
Transition And Organic Metals Composition Catalysts For Addition Polymerization (AREA)
Indole Compounds (AREA)
Agricultural Chemicals And Associated Chemicals (AREA)
Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Cephalosporin Compounds (AREA)
Physical Or Chemical Processes And Apparatus (AREA)
Adhesives Or Adhesive Processes (AREA)
Polymers With Sulfur, Phosphorus Or Metals In The Main Chain (AREA)
Dental Preparations (AREA)

PT78259A 1983-03-16 1984-03-15 Novel process and product PT78259B (en)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
US47589883A	1983-03-16	1983-03-16

Publications (2)

Publication Number	Publication Date
PT78259A PT78259A (en)	1984-04-01
PT78259B true PT78259B (en)	1986-08-08

Family

ID=23889624

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
PT78259A PT78259B (en)	1983-03-16	1984-03-15	Novel process and product

Country Status (20)

Country	Link
EP (1)	EP0125420B1 (pt)
JP (1)	JPS59176212A (pt)
KR (1)	KR880001755B1 (pt)
AT (1)	ATE31024T1 (pt)
AU (1)	AU562929B2 (pt)
CA (1)	CA1212329A (pt)
DD (1)	DD220225A5 (pt)
DE (1)	DE3467707D1 (pt)
DK (1)	DK162878C (pt)
ES (1)	ES8602633A1 (pt)
FI (1)	FI82188C (pt)
GR (1)	GR81478B (pt)
HU (1)	HU191596B (pt)
IE (1)	IE57031B1 (pt)
IL (1)	IL71248A (pt)
NO (1)	NO164956C (pt)
NZ (1)	NZ207514A (pt)
PT (1)	PT78259B (pt)
YU (1)	YU43349B (pt)
ZA (1)	ZA841916B (pt)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US4933360A (en) *	1983-03-16	1990-06-12	Boehringer Ingelheim Pharmaceuticals, Inc.	Novel chlorthalidone process and product
DE3612212A1 (de) *	1986-04-11	1987-10-15	Basf Ag	Verfahren zur herstellung von festen pharmazeutischen formen
WO1988000040A1 (en) *	1986-07-02	1988-01-14	American Health Products Corporation	Topical hair growing composition and kit
US5955475A (en) *	1997-06-30	1999-09-21	Endo Pharmaceuticals Inc.	Process for manufacturing paroxetine solid dispersions
US6264981B1 (en) *	1999-10-27	2001-07-24	Anesta Corporation	Oral transmucosal drug dosage using solid solution

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US3055904A (en) *	1957-11-04	1962-09-25	Geigy Chem Corp	New isoindoline derivatives
US4128632A (en) *	1978-02-13	1978-12-05	Merck & Co., Inc.	Solubilization of Rafoxanide
US4285665A (en) *	1978-05-08	1981-08-25	Johnson, Matthey & Co., Limited	Engines

1984
- 1984-03-14 FI FI841019A patent/FI82188C/fi not_active IP Right Cessation
- 1984-03-14 YU YU458/84A patent/YU43349B/xx unknown
- 1984-03-14 DD DD84260896A patent/DD220225A5/de not_active IP Right Cessation
- 1984-03-15 IL IL71248A patent/IL71248A/xx not_active IP Right Cessation
- 1984-03-15 NO NO841010A patent/NO164956C/no unknown
- 1984-03-15 HU HU841028A patent/HU191596B/hu not_active IP Right Cessation
- 1984-03-15 AT AT84102825T patent/ATE31024T1/de not_active IP Right Cessation
- 1984-03-15 CA CA000449692A patent/CA1212329A/en not_active Expired
- 1984-03-15 PT PT78259A patent/PT78259B/pt not_active IP Right Cessation
- 1984-03-15 KR KR1019840001307A patent/KR880001755B1/ko not_active Expired
- 1984-03-15 DE DE8484102825T patent/DE3467707D1/de not_active Expired
- 1984-03-15 NZ NZ207514A patent/NZ207514A/en unknown
- 1984-03-15 ZA ZA841916A patent/ZA841916B/xx unknown
- 1984-03-15 EP EP84102825A patent/EP0125420B1/en not_active Expired
- 1984-03-15 GR GR74116A patent/GR81478B/el unknown
- 1984-03-15 ES ES530628A patent/ES8602633A1/es not_active Expired
- 1984-03-15 DK DK156784A patent/DK162878C/da not_active IP Right Cessation
- 1984-03-15 IE IE647/84A patent/IE57031B1/en unknown
- 1984-03-16 JP JP59050836A patent/JPS59176212A/ja active Pending
- 1984-03-16 AU AU25696/84A patent/AU562929B2/en not_active Ceased

Also Published As

Publication number	Publication date
YU45884A (en)	1987-06-30
ATE31024T1 (de)	1987-12-15
FI82188C (fi)	1991-02-11
FI841019A0 (fi)	1984-03-14
HU191596B (en)	1987-03-30
EP0125420A2 (en)	1984-11-21
IE57031B1 (en)	1992-03-25
IL71248A0 (en)	1984-06-29
DK162878B (da)	1991-12-23
NO164956C (no)	1990-12-05
AU2569684A (en)	1984-09-20
NZ207514A (en)	1987-02-20
DE3467707D1 (en)	1988-01-07
EP0125420A3 (en)	1985-03-13
NO164956B (no)	1990-08-27
GR81478B (pt)	1984-12-11
EP0125420B1 (en)	1987-11-25
PT78259A (en)	1984-04-01
YU43349B (en)	1989-06-30
IL71248A (en)	1987-02-27
AU562929B2 (en)	1987-06-25
NO841010L (no)	1984-09-17
HUT34343A (en)	1985-03-28
ES530628A0 (es)	1985-12-01
DD220225A5 (de)	1985-03-27
IE840647L (en)	1984-09-16
ZA841916B (en)	1985-11-27
DK156784D0 (da)	1984-03-15
DK156784A (da)	1984-09-17
JPS59176212A (ja)	1984-10-05
DK162878C (da)	1992-05-18
KR880001755B1 (ko)	1988-09-12
CA1212329A (en)	1986-10-07
ES8602633A1 (es)	1985-12-01
FI82188B (fi)	1990-10-31
KR840007874A (ko)	1984-12-11
FI841019L (fi)	1984-09-17

Legal Events

Date

Code

Title

Description

2001-06-29

MM3A

Annulment or lapse

Free format text: LAPSE DUE TO NON-PAYMENT OF FEES

Effective date: 20010228

Publication	Publication Date	Title
PT78259A (en)	1984-04-01	Novel process and product
JPS56802A (en)	1981-01-07	Preparation of hydroxypropyl-cellulose
JPS57192392A (en)	1982-11-26	Production of 3-alkoxymethylcephalosporin
JPS57102902A (en)	1982-06-26	Water-soluble cellulose mixed ether containing phosphonomethyl substituent and manufacture
ES8204425A1 (es)	1982-05-16	Un proceso para la preparacion de cimetidina
JPS57203049A (en)	1982-12-13	Preparation of amide derivative
GB1278128A (en)	1972-06-14	Amido-methyl-polyglycol formals and a process for preparing them
ES479627A1 (es)	1979-08-01	Un procedimiento para la preparacion de 1,4-bis-piperonilpi-peracina y similares.
JPS57185234A (en)	1982-11-15	Preparation of hydroxyphenylacetic acid
JPS5794003A (en)	1982-06-11	Perfluorocarbon polymer and its production
JPS5446779A (en)	1979-04-12	Preparation of 3-isoxazolylurea
JPS5569563A (en)	1980-05-26	Preparation of 2-methoxy-5-sulfamoylbenzoic acid amide
JPS5547651A (en)	1980-04-04	Production of sulfoxyimine
ES8303331A1 (es)	1983-02-01	Un procedimiento para preparar un pirrol-2-acetato de alquilo inferior sustituido en las posiciones 1 y 4.
JPS54122257A (en)	1979-09-21	Silicon-containing vinylphenol derivative and its preparation
JPS55145699A (en)	1980-11-13	Steroid double salt effective for chemotheraphy
JPS51133249A (en)	1976-11-18	A process for preparing alkyl-2,4- dichloro-nitrophenylcarbonates
JPS5214599A (en)	1977-02-03	Process for the production of sodium phosphate using a diaphragm proce ss caustic soda
JPS57185283A (en)	1982-11-15	Preparation of aminoalcohol derivative
JPS5210291A (en)	1977-01-26	Process for preparing thienopyridine carboxylic acid derivatives
JPS57120574A (en)	1982-07-27	Production of guanidine derivative
JPS5564548A (en)	1980-05-15	Preparation of ester
JPS57193478A (en)	1982-11-27	Ansa-azacyclophanetriols and their preparation
JPS54103849A (en)	1979-08-15	Production of aryloxyalkoxysilane
JPS55122755A (en)	1980-09-20	Production of n-carboxymethyltaurine alkali metal salt