PT84398B - Processo para a preparacao de uma formulacao farmaceutica injectavel estavel de di-hidrocloreto de 1,4-di-hidroxi-5,8-bis-{2-(2-hidroxietilamino)-etilamino}antraquinona - Google Patents

Processo para a preparacao de uma formulacao farmaceutica injectavel estavel de di-hidrocloreto de 1,4-di-hidroxi-5,8-bis-{2-(2-hidroxietilamino)-etilamino}antraquinona

Info

Publication number: PT84398B
Authority: PT; Portugal
Prior art keywords: antraquinone; hydroxyethylamino; ethylamino; dihydroxy; bis
Prior art date: 1986-03-07

Application number

PT84398A

Other languages

English (en)

Other versions

PT84398A (en

Inventor

Kieran George Mooney

Narendra Ragjunathji Desai

Pradeep Niphadkar

Paul N Jones

Original Assignee

American Cyanamid Co

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1986-03-07

Filing date

1987-03-04

Publication date

1989-10-04

1987-03-04 Application filed by American Cyanamid Co filed Critical American Cyanamid Co

1987-04-01 Publication of PT84398A publication Critical patent/PT84398A/pt

1989-10-04 Publication of PT84398B publication Critical patent/PT84398B/pt

Links

239000008194 pharmaceutical composition Substances 0.000 title abstract 3
-1 2-HYDROXYETHYLAMINO Chemical class 0.000 title 1
QYRFJLLXPINATB-UHFFFAOYSA-N hydron;2,4,5,6-tetrafluorobenzene-1,3-diamine;dichloride Chemical compound Cl.Cl.NC1=C(F)C(N)=C(F)C(F)=C1F QYRFJLLXPINATB-UHFFFAOYSA-N 0.000 title 1
238000000034 method Methods 0.000 title 1
KKZJGLLVHKMTCM-UHFFFAOYSA-N mitoxantrone Chemical compound O=C1C2=C(O)C=CC(O)=C2C(=O)C2=C1C(NCCNCCO)=CC=C2NCCNCCO KKZJGLLVHKMTCM-UHFFFAOYSA-N 0.000 abstract 1

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/13—Amines
- A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/02—Inorganic compounds
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/16—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing nitrogen, e.g. nitro-, nitroso-, azo-compounds, nitriles, cyanates
- A61K47/18—Amines; Amides; Ureas; Quaternary ammonium compounds; Amino acids; Oligopeptides having up to five amino acids
- A61K47/183—Amino acids, e.g. glycine, EDTA or aspartame

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Veterinary Medicine (AREA)
Pharmacology & Pharmacy (AREA)
Epidemiology (AREA)
Medicinal Chemistry (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Engineering & Computer Science (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Dermatology (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Oil, Petroleum & Natural Gas (AREA)
Inorganic Chemistry (AREA)
Dispersion Chemistry (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Medicinal Preparation (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Steroid Compounds (AREA)

PT84398A 1986-03-07 1987-03-04 Processo para a preparacao de uma formulacao farmaceutica injectavel estavel de di-hidrocloreto de 1,4-di-hidroxi-5,8-bis-{2-(2-hidroxietilamino)-etilamino}antraquinona PT84398B (pt)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
US83724386A	1986-03-07	1986-03-07

Publications (2)

Publication Number	Publication Date
PT84398A PT84398A (en)	1987-04-01
PT84398B true PT84398B (pt)	1989-10-04

Family

ID=25273922

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
PT84398A PT84398B (pt)	1986-03-07	1987-03-04	Processo para a preparacao de uma formulacao farmaceutica injectavel estavel de di-hidrocloreto de 1,4-di-hidroxi-5,8-bis-{2-(2-hidroxietilamino)-etilamino}antraquinona

Country Status (21)

Country	Link
EP (1)	EP0236822B1 (pt)
JP (1)	JPH0717500B2 (pt)
KR (1)	KR900002030B1 (pt)
AT (1)	ATE59290T1 (pt)
AU (1)	AU593330B2 (pt)
CA (1)	CA1283607C (pt)
DE (1)	DE3766984D1 (pt)
DK (1)	DK166754B1 (pt)
ES (1)	ES2033247T3 (pt)
FI (1)	FI84977C (pt)
GR (1)	GR3001503T3 (pt)
HK (1)	HK63991A (pt)
HU (1)	HU199286B (pt)
IE (1)	IE60025B1 (pt)
IL (1)	IL81681A (pt)
NO (1)	NO173635C (pt)
NZ (1)	NZ219454A (pt)
PH (1)	PH22808A (pt)
PT (1)	PT84398B (pt)
SG (1)	SG45292G (pt)
ZA (1)	ZA871652B (pt)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
ATE188870T1 (de) *	1994-10-04	2000-02-15	Lohmann Rudolf Lomapharm	Lösungen von anthrachinonen zur parenteralen applikation
DE19818802A1 (de) *	1998-04-27	1999-10-28	Dresden Arzneimittel	Stabile Mitoxantron-Lösungen
TW200526268A (en) *	2003-12-17	2005-08-16	Takeda Pharmaceutical	Injectable composition
CN103260616B (zh) *	2010-12-09	2015-09-09	丸石制药株式会社	对乙酰氨基酚的稳定化剂
CN114601791B (zh) *	2020-12-08	2023-09-19	成都倍特药业股份有限公司	一种盐酸米托蒽醌液体制剂及其制备方法

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US3230143A (en) *	1965-05-14	1966-01-18	Merck & Co Inc	Antihypertensive injection methods using acid addition salts of alkyl esters of alpha-methyl-3, 4-dihy-droxyphenylalanine
US4223022A (en) *	1978-01-16	1980-09-16	Schering Corporation	Stabilized aminoglycoside antibiotic formulations
US4328213A (en) *	1979-11-28	1982-05-04	Schering Corporation	Stable injectable labetalol formulation
DE3574932D1 (de) *	1984-02-27	1990-02-01	American Cyanamid Co	Verwendung von 1,4 bisubstituierten anthrachinonen zur herstellung von immunsuppressiva.

1987
- 1987-02-20 AT AT87102448T patent/ATE59290T1/de not_active IP Right Cessation
- 1987-02-20 ES ES198787102448T patent/ES2033247T3/es not_active Expired - Lifetime
- 1987-02-20 DE DE8787102448T patent/DE3766984D1/de not_active Expired - Lifetime
- 1987-02-20 EP EP87102448A patent/EP0236822B1/en not_active Expired - Lifetime
- 1987-02-26 IL IL81681A patent/IL81681A/xx not_active IP Right Cessation
- 1987-03-02 NZ NZ219454A patent/NZ219454A/en unknown
- 1987-03-04 PH PH34969A patent/PH22808A/en unknown
- 1987-03-04 PT PT84398A patent/PT84398B/pt unknown
- 1987-03-05 CA CA000531200A patent/CA1283607C/en not_active Expired - Lifetime
- 1987-03-06 ZA ZA871652A patent/ZA871652B/xx unknown
- 1987-03-06 IE IE56987A patent/IE60025B1/en not_active IP Right Cessation
- 1987-03-06 HU HU87969A patent/HU199286B/hu not_active IP Right Cessation
- 1987-03-06 KR KR1019870002031A patent/KR900002030B1/ko not_active Expired
- 1987-03-06 JP JP62050398A patent/JPH0717500B2/ja not_active Expired - Lifetime
- 1987-03-06 FI FI870994A patent/FI84977C/fi not_active IP Right Cessation
- 1987-03-06 DK DK116687A patent/DK166754B1/da not_active IP Right Cessation
- 1987-03-06 AU AU69773/87A patent/AU593330B2/en not_active Expired
- 1987-03-06 NO NO870950A patent/NO173635C/no unknown
1991
- 1991-02-26 GR GR90400362T patent/GR3001503T3/el not_active IP Right Cessation
- 1991-08-15 HK HK639/91A patent/HK63991A/en not_active IP Right Cessation
1992
- 1992-04-24 SG SG45292A patent/SG45292G/en unknown

Also Published As

Publication number	Publication date
GR3001503T3 (en)	1992-11-23
FI870994L (fi)	1987-09-08
JPS62265220A (ja)	1987-11-18
SG45292G (en)	1992-06-12
HK63991A (en)	1991-08-23
IE870569L (en)	1987-09-07
DK116687D0 (da)	1987-03-06
FI84977C (fi)	1992-02-25
IL81681A0 (en)	1987-09-16
NO173635C (no)	1994-01-12
FI84977B (fi)	1991-11-15
AU6977387A (en)	1987-09-10
JPH0717500B2 (ja)	1995-03-01
EP0236822A2 (en)	1987-09-16
DK116687A (da)	1987-09-08
DE3766984D1 (de)	1991-02-07
NZ219454A (en)	1989-04-26
IL81681A (en)	1991-01-31
CA1283607C (en)	1991-04-30
NO173635B (no)	1993-10-04
ATE59290T1 (de)	1991-01-15
ZA871652B (en)	1987-08-28
ES2033247T3 (es)	1993-03-16
HUT47020A (en)	1989-01-30
KR870008581A (ko)	1987-10-19
EP0236822B1 (en)	1990-12-27
NO870950D0 (no)	1987-03-06
PH22808A (en)	1988-12-27
AU593330B2 (en)	1990-02-08
FI870994A0 (fi)	1987-03-06
PT84398A (en)	1987-04-01
EP0236822A3 (en)	1989-01-11
NO870950L (no)	1987-09-08
IE60025B1 (en)	1994-05-18
HU199286B (en)	1990-02-28
KR900002030B1 (ko)	1990-03-31
DK166754B1 (da)	1993-07-12

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Legal Events

Date

Code

Title

Description

2004-01-30

PD3A

Change of proprietorship

Free format text: WYETH HOLDINGS CORPORATION US

Effective date: 20031117

2004-01-30

TE3A

Change of address (patent)

Free format text: AMERICAN CYANAMID COMPANY US

Effective date: 20031117