PT89222A - Processo para a preparacao de acidos quinolina-carboxilicos heterociclicos substituidos - Google Patents
Processo para a preparacao de acidos quinolina-carboxilicos heterociclicos substituidosInfo
- Publication number
- PT89222A PT89222A PT89222A PT8922288A PT89222A PT 89222 A PT89222 A PT 89222A PT 89222 A PT89222 A PT 89222A PT 8922288 A PT8922288 A PT 8922288A PT 89222 A PT89222 A PT 89222A
- Authority
- PT
- Portugal
- Prior art keywords
- carboxylic acids
- preparation
- substituted heterocyclic
- heterocyclic acid
- acid quinoline
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
- C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
- C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D215/48—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
- C07D215/54—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen attached in position 3
- C07D215/56—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen attached in position 3 with oxygen atoms in position 4
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D513/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00
- C07D513/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00 in which the condensed system contains two hetero rings
- C07D513/04—Ortho-condensed systems
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Oncology (AREA)
- Pharmacology & Pharmacy (AREA)
- Communicable Diseases (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Quinoline Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| PCT/US1987/003412 WO1989005643A1 (en) | 1987-12-18 | 1987-12-18 | Heterocyclic-substituted quinoline-carboxylic acids |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| PT89222A true PT89222A (pt) | 1989-12-29 |
| PT89222B PT89222B (pt) | 1994-11-30 |
Family
ID=22202722
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PT89222A PT89222B (pt) | 1987-12-18 | 1988-12-15 | Processo para a preparacao de acidos quinolina-carboxilicos heterociclicos substituidos |
Country Status (18)
| Country | Link |
|---|---|
| US (1) | US5037834A (pt) |
| EP (1) | EP0321191B1 (pt) |
| JP (1) | JPH0725757B2 (pt) |
| KR (1) | KR900008568B1 (pt) |
| AT (1) | ATE113599T1 (pt) |
| AU (1) | AU600188B2 (pt) |
| DE (1) | DE3852010T2 (pt) |
| DK (1) | DK699788A (pt) |
| ES (1) | ES2061695T3 (pt) |
| FI (1) | FI90239C (pt) |
| IE (1) | IE65732B1 (pt) |
| IL (1) | IL88664A (pt) |
| MY (1) | MY104072A (pt) |
| NO (1) | NO178149C (pt) |
| NZ (1) | NZ227357A (pt) |
| PT (1) | PT89222B (pt) |
| WO (1) | WO1989005643A1 (pt) |
| ZA (1) | ZA889395B (pt) |
Families Citing this family (20)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0251308B1 (de) * | 1986-07-04 | 1990-11-22 | Chemie Linz Gesellschaft m.b.H. | 4-Chinolon-3-carbonsäurederivate, Verfahren zu ihrer Herstellung und diese enthaltende pharmazeutische Präparate |
| US5093515A (en) * | 1987-08-14 | 1992-03-03 | Asahi Glass Company Ltd. | Fluorinated benzoyl compounds |
| EP0303291B1 (en) * | 1987-08-14 | 1995-04-26 | Asahi Glass Company Ltd. | Fluorinated benzoyl compounds |
| US5214051A (en) * | 1989-08-01 | 1993-05-25 | Pfizer Inc. | Thiazolyl and oxazolyl[5,4-c]piperidyl-substituted quinolone-carboxylic acid and related analogs thereof having antibacterial properties are disclosed |
| KR910009333B1 (ko) * | 1989-10-23 | 1991-11-11 | 재단법인 한국화학연구소 | 항균작용을 갖는 퀴놀린계 화합물과 그의 제조방법 |
| KR910009330B1 (ko) * | 1989-10-23 | 1991-11-11 | 재단법인 한국화학연구소 | 항균작용을 갖는 퀴놀린계 화합물과 그의 제조방법 |
| DE4121214A1 (de) * | 1991-06-27 | 1993-01-14 | Bayer Ag | 7-azaisoindolinyl-chinolon- und -naphthyridoncarbonsaeure-derivate |
| DE4342186A1 (de) * | 1993-12-10 | 1995-06-14 | Bayer Ag | Eintopfverfahren zur Herstellung von 3-Chinoloncarbonsäurederivaten |
| DE19652239A1 (de) * | 1996-12-16 | 1998-06-18 | Bayer Ag | Verwendung von 7-(2-Oxa-5,8-diazabicyclo[4.3.0]non-8-yl)-chinolon- und -naphthyridoncarbonsäure-Derivaten zur Therapie von Helicobacter-pylori-Infektionen und den damit assoziierten gastroduodenalen Erkrankungen |
| US6608081B2 (en) | 1999-08-12 | 2003-08-19 | Ortho-Mcneil Pharmaceutical, Inc. | Bicyclic heterocyclic substituted phenyl oxazolidinone antibacterials, and related compositions and methods |
| US6855385B2 (en) * | 2000-05-31 | 2005-02-15 | Ttm Advanced Circuits, Inc. | PCB support plate for PCB via fill |
| US6951863B2 (en) * | 2001-02-07 | 2005-10-04 | Ortho-Mcneil Pharmaceutical, Inc. | Pyridoarylphenly oxazolidinone antibacterials, and related compositions and methods |
| BR0314759A (pt) * | 2002-09-26 | 2005-07-26 | Pfizer | Derivados de pirazol |
| CL2004000553A1 (es) * | 2003-03-20 | 2005-02-04 | Actelion Pharmaceuticals Ltd | Uso de compuestos derivados de guanidina como antagonistas del receptor de neuropeptido ff; compuestos derivados de guanidina; procedimientos de preparacion; y composicion farmaceutica que los comprende. |
| GB0610804D0 (en) * | 2006-05-31 | 2006-07-12 | Portela & Ca Sa | New crystal forms |
| KR20090047450A (ko) * | 2006-08-04 | 2009-05-12 | 메르츠 파마 게엠베하 운트 코. 카가아 | 치환된 피라졸로피리미딘, 이의 제조 방법 및 의약품으로서의 이의 용도 |
| EP2231648A1 (en) * | 2007-12-05 | 2010-09-29 | BIAL - Portela & Ca., S.A. | New salts and crystal forms |
| CN105017151B (zh) * | 2011-08-31 | 2019-04-02 | 大塚制药株式会社 | 喹诺酮化合物 |
| TWI695000B (zh) * | 2017-10-29 | 2020-06-01 | 中國醫藥大學 | 用於抑制ａｄａｍ９活性之化合物、其醫藥組合物及其用途 |
| US20240132517A1 (en) * | 2021-02-10 | 2024-04-25 | Goharmony Therapeutics (Shenzhen) Co., Ltd. | Macrocyclic compound, pharmaceutical composition, and use thereof |
Family Cites Families (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| SE418966B (sv) * | 1974-02-18 | 1981-07-06 | Haessle Ab | Analogiforfarande for framstellning av foreningar med magsyrasekretionsinhiberande verkan |
| JPS53141286A (en) * | 1977-05-16 | 1978-12-08 | Kyorin Seiyaku Kk | Novel substituted quinolinecarboxylic acid |
| JPS5746986A (en) * | 1980-09-02 | 1982-03-17 | Dai Ichi Seiyaku Co Ltd | Pyrido(1,2,3-de)(1,4)benzoxazine derivative |
| IE55898B1 (en) * | 1982-09-09 | 1991-02-14 | Warner Lambert Co | Antibacterial agents |
| US4665079A (en) * | 1984-02-17 | 1987-05-12 | Warner-Lambert Company | Antibacterial agents |
| JPS59128383A (ja) * | 1982-12-29 | 1984-07-24 | Kanebo Ltd | 新規キノリンカルボン酸誘導体および該化合物を有効成分とする抗菌剤 |
| JPS59204194A (ja) * | 1983-05-09 | 1984-11-19 | Hokuriku Seiyaku Co Ltd | ７−ジアザビシクロアルカン置換−６，８−ジフオロ−４−オキソ−１，４−ジヒドロキノリン−３−カルボン酸誘導体 |
| US4571396A (en) * | 1984-04-16 | 1986-02-18 | Warner-Lambert Company | Antibacterial agents |
| US4636506A (en) * | 1984-12-06 | 1987-01-13 | Pfizer, Inc. | 7-heterocyclic-1,4-dihydroquinolones |
| US4657913A (en) * | 1985-04-18 | 1987-04-14 | Warner-Lambert Company | Trifluoro- quinoline -3- carboxylic acids and their use as anti-bacterial agents |
| DE3519286A1 (de) * | 1985-05-30 | 1986-12-04 | Bayer Ag, 5090 Leverkusen | 7-azolyl-1-cyclopropyl-1,4-dihydro-4-oxo-3- chinolincarbonsaeuren und -1,8-naphthyridin-3-carbonsaeuren, verfahren zu ihrer herstellung sowie diese enthaltende antibakterielle mittel |
| IN166416B (pt) * | 1985-09-18 | 1990-05-05 | Pfizer |
-
1987
- 1987-12-18 WO PCT/US1987/003412 patent/WO1989005643A1/en not_active Ceased
-
1988
- 1988-12-12 IL IL88664A patent/IL88664A/xx not_active IP Right Cessation
- 1988-12-14 EP EP88311797A patent/EP0321191B1/en not_active Expired - Lifetime
- 1988-12-14 MY MYPI88001451A patent/MY104072A/en unknown
- 1988-12-14 ES ES88311797T patent/ES2061695T3/es not_active Expired - Lifetime
- 1988-12-14 AT AT88311797T patent/ATE113599T1/de not_active IP Right Cessation
- 1988-12-14 DE DE3852010T patent/DE3852010T2/de not_active Expired - Fee Related
- 1988-12-15 ZA ZA889395A patent/ZA889395B/xx unknown
- 1988-12-15 PT PT89222A patent/PT89222B/pt not_active IP Right Cessation
- 1988-12-16 DK DK699788A patent/DK699788A/da not_active Application Discontinuation
- 1988-12-16 AU AU26987/88A patent/AU600188B2/en not_active Ceased
- 1988-12-16 JP JP31934188A patent/JPH0725757B2/ja not_active Expired - Lifetime
- 1988-12-16 NZ NZ227357A patent/NZ227357A/en unknown
- 1988-12-16 IE IE376388A patent/IE65732B1/en not_active IP Right Cessation
- 1988-12-17 KR KR1019880016841A patent/KR900008568B1/ko not_active Expired
-
1989
- 1989-08-01 US US07/435,496 patent/US5037834A/en not_active Expired - Lifetime
- 1989-08-17 NO NO893305A patent/NO178149C/no unknown
- 1989-08-17 FI FI893883A patent/FI90239C/fi not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| FI90239C (fi) | 1994-01-10 |
| JPH0725757B2 (ja) | 1995-03-22 |
| AU600188B2 (en) | 1990-08-02 |
| KR890009925A (ko) | 1989-08-04 |
| FI893883A0 (fi) | 1989-08-17 |
| ZA889395B (en) | 1990-08-29 |
| DK699788A (da) | 1989-08-11 |
| NO893305D0 (no) | 1989-08-17 |
| NO893305L (no) | 1989-10-17 |
| FI893883A7 (fi) | 1989-08-17 |
| ES2061695T3 (es) | 1994-12-16 |
| IL88664A0 (en) | 1989-07-31 |
| IL88664A (en) | 1993-08-18 |
| MY104072A (en) | 1993-11-30 |
| NO178149C (no) | 1996-01-31 |
| NZ227357A (en) | 1991-04-26 |
| KR900008568B1 (ko) | 1990-11-24 |
| JPH01211587A (ja) | 1989-08-24 |
| EP0321191A2 (en) | 1989-06-21 |
| ATE113599T1 (de) | 1994-11-15 |
| IE883763L (en) | 1989-06-18 |
| AU2698788A (en) | 1989-06-22 |
| EP0321191B1 (en) | 1994-11-02 |
| IE65732B1 (en) | 1995-11-15 |
| DK699788D0 (da) | 1988-12-16 |
| DE3852010T2 (de) | 1995-03-09 |
| WO1989005643A1 (en) | 1989-06-29 |
| PT89222B (pt) | 1994-11-30 |
| EP0321191A3 (en) | 1991-02-27 |
| FI90239B (fi) | 1993-09-30 |
| NO178149B (no) | 1995-10-23 |
| DE3852010D1 (de) | 1994-12-08 |
| US5037834A (en) | 1991-08-06 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| PT89222A (pt) | Processo para a preparacao de acidos quinolina-carboxilicos heterociclicos substituidos | |
| BR9005452A (pt) | Processo para preparacao de compostos e os ditos compostos | |
| DK140996A (da) | Fremgangsmåde til fremstilling af 2,3,4,5-tetraflour-6-alkyl-benzoesyreforbindelser | |
| SE8901464L (sv) | Pyridonkarboxylsyraderivat och salter daerav, foerfarande foer deras framstaellning samt antibakteriella medel innehaallande dessa | |
| NO873125D0 (no) | Fremgangsmaate for fremstilling av antibakterielle forbindelser. | |
| AU7632691A (en) | Intermediates for production of 1-tertiary-alkyl-substituted naphthyridine- and quinoline-carboxylic acid antibacterial agents | |
| NO850216L (no) | Analogifremgangsmaate for fremstilling av terapeutisk aktive substituerte 5,11-dihydro-6-dibenz(b,e)-azepin-6-on-derivater | |
| ES515649A0 (es) | Un procedimiento para la preparacion de 1,1-dioxidos de acidos penam-3-carboxilicos. | |
| ES555612A0 (es) | Procedimiento para la produccion de derivados del acido 7-amino-3-alcoximetil-3-cefem-4-carboxilico | |
| NO870482D0 (no) | Fremgangsmaate ved fremstilling av nye karboksylsyreamider. | |
| ATE103276T1 (de) | Verfahren zur herstellung von chinolin-2,3carbons|ure. | |
| BR8801010A (pt) | Processo para conversao de acido carboxilico ou do grupo haleto do acido carboxilico | |
| ES2048213T3 (es) | Procedimiento de preparacion de anhidridos de acidos. | |
| ES2092730T3 (es) | Procedimiento microbiologico para la preparacion de acido 5-hidroxi-2-pirazina-carboxilico. | |
| ATE46908T1 (de) | Verfahren zur herstellung von 4,5-dihydrodithieno(3,4b:3',4'-e>-azepin-5,9-dion. | |
| ES2063240T3 (es) | Nuevos derivados de acido amino-carboxilico. | |
| FI934054L (fi) | Menetelmä antibakteeristen karboksyylihappojohdannaisten valmistuksessa käyttökelpoisten välituotteiden valmistamiseksi | |
| FR2612183B1 (fr) | Nouveaux composes chimiques trifluoromethyles et leur procede de preparation | |
| ATE5721T1 (de) | Verfahren zur herstellung von 7-chlor-1,2,3,4tetrahydro-4-chinolon. | |
| ATE132865T1 (de) | 3-anilino-2-hydroxycarbonyl-4-thiophenessigsäur n | |
| ATE144257T1 (de) | Tetrahydro-4-phenylimino-3-thiophenessigsäuren | |
| MD71B1 (ro) | Amestecurile de anhidride ale acizilor chinolin-carboxilic si ale celui boric ca produse intermediare pentru obtinerea derivatilor piperozilin-3-acid chinolin-carboxilic care poseda proprietati antibacteriale |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FG3A | Patent granted, date of granting |
Effective date: 19940518 |
|
| MM3A | Annulment or lapse |
Free format text: LAPSE DUE TO NON-PAYMENT OF FEES Effective date: 19981130 |