PT89236A - Processo para a preparacao de compostos beta-lactamicos - Google Patents

Processo para a preparacao de compostos beta-lactamicos

Info

Publication number: PT89236A
Authority: PT; Portugal
Prior art keywords: compounds; beta; lactamic; preparation; vivo hydrolysable
Prior art date: 1987-12-18

Application number

PT89236A

Other languages

English (en)

Other versions

PT89236B (pt

Inventor

Nigel John Perryman Broom

Gerald Brooks

Steven Coulton

Original Assignee

Beecham Group Plc

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1987-12-18

Filing date

1988-12-16

Publication date

1989-12-29

1988-12-16 Application filed by Beecham Group Plc filed Critical Beecham Group Plc

1989-12-29 Publication of PT89236A publication Critical patent/PT89236A/pt

1993-07-30 Publication of PT89236B publication Critical patent/PT89236B/pt

Links

150000001875 compounds Chemical class 0.000 title abstract 3
238000001727 in vivo Methods 0.000 abstract 2
108090000204 Dipeptidase 1 Proteins 0.000 abstract 1
125000002252 acyl group Chemical group 0.000 abstract 1
230000000844 anti-bacterial effect Effects 0.000 abstract 1
102000006635 beta-lactamase Human genes 0.000 abstract 1
150000002148 esters Chemical class 0.000 abstract 1
125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 1
230000002401 inhibitory effect Effects 0.000 abstract 1
150000003839 salts Chemical class 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D499/00—Heterocyclic compounds containing 4-thia-1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. penicillins, penems; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D499/00—Heterocyclic compounds containing 4-thia-1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. penicillins, penems; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
- C07D499/88—Compounds with a double bond between positions 2 and 3 and a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
General Health & Medical Sciences (AREA)
Veterinary Medicine (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Oncology (AREA)
Pharmacology & Pharmacy (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
Communicable Diseases (AREA)
Public Health (AREA)
Chemical Kinetics & Catalysis (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Steroid Compounds (AREA)
Photoreceptors In Electrophotography (AREA)
Cephalosporin Compounds (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Pens And Brushes (AREA)
Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Peptides Or Proteins (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Mechanical Treatment Of Semiconductor (AREA)

PT89236A 1987-12-18 1988-12-16 Processo para a preparacao de compostos beta-lactamicos PT89236B (pt)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
GB878729613A GB8729613D0 (en)	1987-12-18	1987-12-18	Novel compounds

Publications (2)

Publication Number	Publication Date
PT89236A true PT89236A (pt)	1989-12-29
PT89236B PT89236B (pt)	1993-07-30

Family

ID=10628729

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
PT89236A PT89236B (pt)	1987-12-18	1988-12-16	Processo para a preparacao de compostos beta-lactamicos

Country Status (13)

Country	Link
US (1)	US4923856A (pt)
EP (1)	EP0321186B1 (pt)
JP (1)	JPH02287A (pt)
KR (1)	KR890009938A (pt)
AT (1)	ATE102206T1 (pt)
AU (1)	AU621846B2 (pt)
CA (1)	CA1302402C (pt)
DE (1)	DE3888127T2 (pt)
DK (1)	DK702488A (pt)
GB (1)	GB8729613D0 (pt)
NZ (1)	NZ227355A (pt)
PT (1)	PT89236B (pt)
ZA (1)	ZA889397B (pt)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US4945466A (en) *	1989-02-22	1990-07-31	Borland Walter G	Resonant switching converter
AR039476A1 (es) *	2002-05-01	2005-02-23	Wyeth Corp	Proceso para preparar derivados de 6-alquiliden penem
AR039475A1 (es)	2002-05-01	2005-02-23	Wyeth Corp	6-alquiliden-penems triciclicos como inhibidores de beta-lactamasa
AR039774A1 (es)	2002-05-01	2005-03-02	Wyeth Corp	6-alquiliden-penems biciclicos como inhibidores de beta-lactamasas

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
FI82471C (fi) *	1984-01-26	1991-03-11	Beecham Group Plc	Foerfarande foer framstaellning av farmakologiskt aktiva 6-metylenpenemderivater.
US4826833A (en) *	1984-01-30	1989-05-02	Pfizer Inc.	6-(Substituted)methylene-penicillanic and 6-(substituted)hydroxymethylpenicillanic acids and derivatives thereof
GB8518422D0 (en) *	1985-07-22	1985-08-29	Beecham Group Plc	Compounds
GB8711391D0 (en) *	1987-05-14	1987-06-17	Beecham Group Plc	Process

1987
- 1987-12-18 GB GB878729613A patent/GB8729613D0/en active Pending
1988
- 1988-12-13 AT AT88311786T patent/ATE102206T1/de not_active IP Right Cessation
- 1988-12-13 EP EP88311786A patent/EP0321186B1/en not_active Expired - Lifetime
- 1988-12-13 DE DE3888127T patent/DE3888127T2/de not_active Expired - Fee Related
- 1988-12-15 ZA ZA889397A patent/ZA889397B/xx unknown
- 1988-12-16 NZ NZ227355A patent/NZ227355A/en unknown
- 1988-12-16 US US07/286,375 patent/US4923856A/en not_active Expired - Fee Related
- 1988-12-16 AU AU26931/88A patent/AU621846B2/en not_active Ceased
- 1988-12-16 CA CA000586210A patent/CA1302402C/en not_active Expired - Fee Related
- 1988-12-16 PT PT89236A patent/PT89236B/pt not_active IP Right Cessation
- 1988-12-16 DK DK702488A patent/DK702488A/da not_active Application Discontinuation
- 1988-12-17 KR KR1019880016903A patent/KR890009938A/ko not_active Withdrawn
- 1988-12-19 JP JP63320334A patent/JPH02287A/ja active Pending

Also Published As

Publication number	Publication date
EP0321186A1 (en)	1989-06-21
ZA889397B (en)	1990-08-29
ATE102206T1 (de)	1994-03-15
EP0321186B1 (en)	1994-03-02
DK702488D0 (da)	1988-12-16
CA1302402C (en)	1992-06-02
DE3888127D1 (de)	1994-04-07
JPH02287A (ja)	1990-01-05
US4923856A (en)	1990-05-08
AU621846B2 (en)	1992-03-26
PT89236B (pt)	1993-07-30
AU2693188A (en)	1989-06-22
GB8729613D0 (en)	1988-02-03
DK702488A (da)	1989-06-19
KR890009938A (ko)	1989-08-05
NZ227355A (en)	1991-04-26
DE3888127T2 (de)	1994-07-07

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Legal Events

Date

Code

Title

Description

1993-07-30

FG3A

Patent granted, date of granting

Effective date: 19930119

1994-12-30

MM3A

Annulment or lapse

Free format text: LAPSE DUE TO NON-PAYMENT OF FEES

Effective date: 19940731