PT90865A - Processo para a preparacao de compostos de imidazoquinoxalina e de composicoes farmaceuticas que os contem - Google Patents

Processo para a preparacao de compostos de imidazoquinoxalina e de composicoes farmaceuticas que os contem

Info

Publication number: PT90865A
Authority: PT; Portugal
Prior art keywords: preparation; pharmaceutical compositions; compositions containing; compounds; imidazoquinoxaline compounds
Prior art date: 1988-06-14

Application number

PT90865A

Other languages

English (en)

Other versions

PT90865B (pt

Inventor

Holger Claus Hansen

Frank Waetjen

Original Assignee

Ferrosan As

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1988-06-14

Filing date

1989-06-14

Publication date

1989-12-29

1989-06-14 Application filed by Ferrosan As filed Critical Ferrosan As

1989-12-29 Publication of PT90865A publication Critical patent/PT90865A/pt

1994-11-30 Publication of PT90865B publication Critical patent/PT90865B/pt

Links

YELMWJNXDALKFE-UHFFFAOYSA-N 3h-imidazo[4,5-f]quinoxaline Chemical class N1=CC=NC2=C(NC=N3)C3=CC=C21 YELMWJNXDALKFE-UHFFFAOYSA-N 0.000 title abstract 2
238000002360 preparation method Methods 0.000 title abstract 2
239000008194 pharmaceutical composition Substances 0.000 title 1
125000004169 (C1-C6) alkyl group Chemical group 0.000 abstract 2
125000006272 (C3-C7) cycloalkyl group Chemical group 0.000 abstract 1
UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 abstract 1
241000124008 Mammalia Species 0.000 abstract 1
229940125681 anticonvulsant agent Drugs 0.000 abstract 1
239000001961 anticonvulsive agent Substances 0.000 abstract 1
239000002249 anxiolytic agent Substances 0.000 abstract 1
230000000949 anxiolytic effect Effects 0.000 abstract 1
229940005530 anxiolytics Drugs 0.000 abstract 1
210000004556 brain Anatomy 0.000 abstract 1
230000003920 cognitive function Effects 0.000 abstract 1
150000001875 compounds Chemical class 0.000 abstract 1
229910052739 hydrogen Inorganic materials 0.000 abstract 1
239000001257 hydrogen Substances 0.000 abstract 1
239000003326 hypnotic agent Substances 0.000 abstract 1
230000000147 hypnotic effect Effects 0.000 abstract 1
125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/08—Antiepileptics; Anticonvulsants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/20—Hypnotics; Sedatives

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Life Sciences & Earth Sciences (AREA)
Bioinformatics & Cheminformatics (AREA)
Biomedical Technology (AREA)
Neurology (AREA)
Neurosurgery (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Veterinary Medicine (AREA)
Pharmacology & Pharmacy (AREA)
Engineering & Computer Science (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Anesthesiology (AREA)
Pain & Pain Management (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)
Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
Medicinal Preparation (AREA)

PT90865A 1988-06-14 1989-06-14 Processo para a preparacao de compostos de imidazoquinoxalina e de composicoes farmaceuticas que os contem PT90865B (pt)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
DK322088A DK161148C (da)	1988-06-14	1988-06-14	Imidazoquinoxalinforbindelser, fremgangsmaade til fremstilling deraf samt farmaceutiske praeprater indeholdende forbindelserne

Publications (2)

Publication Number	Publication Date
PT90865A true PT90865A (pt)	1989-12-29
PT90865B PT90865B (pt)	1994-11-30

Family

ID=8120424

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
PT90865A PT90865B (pt)	1988-06-14	1989-06-14	Processo para a preparacao de compostos de imidazoquinoxalina e de composicoes farmaceuticas que os contem

Country Status (18)

Country	Link
US (1)	US5034530A (pt)
EP (1)	EP0347094B1 (pt)
JP (1)	JPH0236184A (pt)
KR (1)	KR910000665A (pt)
AT (1)	ATE111100T1 (pt)
AU (1)	AU618366B2 (pt)
CA (1)	CA1327798C (pt)
DE (1)	DE68918003T2 (pt)
DK (1)	DK161148C (pt)
ES (1)	ES2060769T3 (pt)
FI (1)	FI92204C (pt)
IE (1)	IE69963B1 (pt)
IL (1)	IL90543A0 (pt)
NO (1)	NO170806C (pt)
NZ (1)	NZ229499A (pt)
PH (1)	PH26337A (pt)
PT (1)	PT90865B (pt)
ZA (1)	ZA894430B (pt)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
DK160876C (da) *	1987-12-08	1991-10-14	Novo Nordisk As	Imidazoquinoxalinforbindelser, fremgangsmaade til deres fremstilling, anvendelse af forbindelserne og farmaceutiske praeparater, hvori forbindelserne indgaar
US5276028A (en) *	1990-06-22	1994-01-04	Nordisk A/S	Imidazoquinoxaline compounds
DK151890D0 (da) *	1990-06-22	1990-06-22	Ferrosan As	Heterocykliske forbindelser deres fremstilling og brug
US5371080A (en) *	1990-06-22	1994-12-06	Novo Nordisk A/S	Imidazoquinazoline compounds and their use
US5153196A (en) *	1991-06-05	1992-10-06	Eli Lilly And Company	Excitatory amino acid receptor antagonists and methods for the use thereof
KR100207360B1 (ko) *	1991-06-14	1999-07-15	돈 더블유. 슈미츠	이미다조[1,5,-a]퀸옥살린
IL112099A (en) *	1993-12-23	1999-07-14	Ortho Pharma Corp	N-oxides of 4-arylpiperazines and 4-arylpiperidines and pharmaceutical compositions containing them
US6235740B1 (en)	1997-08-25	2001-05-22	Bristol-Myers Squibb Co.	Imidazoquinoxaline protein tyrosine kinase inhibitors
US6635626B1 (en)	1997-08-25	2003-10-21	Bristol-Myers Squibb Co.	Imidazoquinoxaline protein tyrosine kinase inhibitors
CA2322311C (en) *	1998-03-04	2009-10-13	Bristol-Myers Squibb Company	Heterocyclo-substituted imidazopyrazine protein tyrosine kinase inhibitors
US20040180898A1 (en) *	2003-03-03	2004-09-16	Bang-Chi Chen	Processes for preparing imidazoquinoxalinones, heterocyclic-substituted imidazopyrazinones, imidazoquinoxalines and heterocyclic-substituted imidazopyrazines
EP2227472A1 (en) *	2007-11-30	2010-09-15	Elbion Gmbh	Aryl and heteroaryl fused imidazo (1,5-a) pyrazines as inhibitors of phosphodiesterase 10
KR20100110804A (ko) *	2007-11-30	2010-10-13	와이어쓰 엘엘씨	포스포디에스테라제 10의 저해물질로서의 아릴 및 헤테로아릴 융합된 이미다조[1,5-ａ]피라진
TW201111383A (en) *	2009-05-29	2011-04-01	Wyeth Llc	Substituted imidazo[1,5-a]quinoxalines as inhibitors of phosphodiesterase 10

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US4440929A (en) *	1981-07-16	1984-04-03	Usv Pharmaceutical Corporation	Imidazoquinoxaline compounds
DK476885D0 (da) *	1985-10-17	1985-10-17	Ferrosan As	Heterocycliske forbindelser og fremgangsmaader til fremstilling heraf
DE3668116D1 (de) *	1985-10-19	1990-02-15	Beecham Group Plc	Zusammensetzung zur behandlung von infektionen.
DK155524C (da) *	1987-03-18	1989-09-11	Ferrosan As	Kondenserede imidazolderivater og farmaceutiske praeparater indeholdende disse

1988
- 1988-06-14 DK DK322088A patent/DK161148C/da not_active IP Right Cessation
1989
- 1989-06-06 IL IL90543A patent/IL90543A0/xx not_active IP Right Cessation
- 1989-06-07 AT AT89305728T patent/ATE111100T1/de not_active IP Right Cessation
- 1989-06-07 EP EP89305728A patent/EP0347094B1/en not_active Expired - Lifetime
- 1989-06-07 DE DE68918003T patent/DE68918003T2/de not_active Expired - Fee Related
- 1989-06-07 ES ES89305728T patent/ES2060769T3/es not_active Expired - Lifetime
- 1989-06-08 US US07/363,585 patent/US5034530A/en not_active Expired - Fee Related
- 1989-06-08 PH PH38760A patent/PH26337A/en unknown
- 1989-06-12 NZ NZ229499A patent/NZ229499A/xx unknown
- 1989-06-12 ZA ZA894430A patent/ZA894430B/xx unknown
- 1989-06-13 CA CA000602682A patent/CA1327798C/en not_active Expired - Fee Related
- 1989-06-13 NO NO892456A patent/NO170806C/no unknown
- 1989-06-13 IE IE189289A patent/IE69963B1/en not_active IP Right Cessation
- 1989-06-13 JP JP1148537A patent/JPH0236184A/ja active Pending
- 1989-06-13 AU AU36244/89A patent/AU618366B2/en not_active Ceased
- 1989-06-14 PT PT90865A patent/PT90865B/pt not_active IP Right Cessation
- 1989-06-14 KR KR1019890008164A patent/KR910000665A/ko not_active Ceased
- 1989-06-14 FI FI892908A patent/FI92204C/fi not_active IP Right Cessation

Also Published As

Publication number	Publication date
FI92204B (fi)	1994-06-30
FI892908L (fi)	1989-12-15
IE891892L (en)	1989-12-14
DK322088A (da)	1990-03-27
FI92204C (fi)	1994-10-10
DK322088D0 (da)	1988-06-14
ZA894430B (en)	1990-02-28
AU3624489A (en)	1989-12-21
DK161148B (da)	1991-06-03
US5034530A (en)	1991-07-23
FI892908A0 (fi)	1989-06-14
NO892456D0 (no)	1989-06-13
ATE111100T1 (de)	1994-09-15
ES2060769T3 (es)	1994-12-01
DK161148C (da)	1991-11-18
DE68918003T2 (de)	1995-01-05
DE68918003D1 (de)	1994-10-13
NO170806B (no)	1992-08-31
NZ229499A (en)	1991-04-26
KR910000665A (ko)	1991-01-30
JPH0236184A (ja)	1990-02-06
IE69963B1 (en)	1996-10-16
EP0347094A1 (en)	1989-12-20
PT90865B (pt)	1994-11-30
PH26337A (en)	1992-04-29
EP0347094B1 (en)	1994-09-07
IL90543A0 (en)	1990-01-18
NO170806C (no)	1992-12-09
CA1327798C (en)	1994-03-15
NO892456L (no)	1989-12-15
AU618366B2 (en)	1991-12-19

Legal Events

Date

Code

Title

Description

1994-11-30

FG3A

Patent granted, date of granting

Effective date: 19940518

2000-03-31

MM3A

Annulment or lapse

Free format text: LAPSE DUE TO NON-PAYMENT OF FEES

Effective date: 19991130

Publication	Publication Date	Title
PT90865A (pt)	1989-12-29	Processo para a preparacao de compostos de imidazoquinoxalina e de composicoes farmaceuticas que os contem
BR9307739A (pt)	1999-05-25	Composições de perácido processo de desinfecção e processo para a preparação de uma composição
PT96096A (pt)	1991-09-30	Processo de estabilizacao de uma mistura aquosa de um composto heterociclico de azoto e de preparacao de composicoes estabilizadas com metionina
PT89170A (pt)	1989-12-29	Processo de preparacao de compostos de imidazoquinoxalina terapeuticamente activos e de composicoes farmaceuticas que os contem
PT84690B (pt)	1989-11-30	Processo de preparacao de novos derivados da benzodiazepina e de composicoes farmaceuticas que os contem
PT83573B (pt)	1988-10-14	Processo de preparacao de compostos heterociclicos de quinazolina e de seus intermediarios e de composicoes farmaceuticas
BR9304780A (pt)	1994-07-05	Composto, processo para preparar o composto, composição farmacêutica e uso
BR9601178A (pt)	1998-03-31	Composição uso processo para a estabilização de um polímero processo para a preparação de um composto e composto obtido
PT95973A (pt)	1991-09-13	Processo de preparacao de compostos da imidazoquinoxalina e de composicoes farmaceuticas
BR8906421A (pt)	1990-08-28	Processo para preparacao de monopersulfato de piridina-3-acido peroxicarboxilico
PT98063A (pt)	1992-03-31	Processo de preparacao de compostos de 4-amino-imidazo-quinoxalina e de 5-amino-imidazo-quinazolina e de composicoes farmaceuticas
NO884431L (no)	1989-04-07	Fremgangsmaate for fremstilling av heterocykliske forbindelser.
PT97663A (pt)	1992-03-31	Processo de preparacao de 3'-desamino-4'-desoxi-4'-amino-8-fluoro-antraciclinas, de composicoes farmaceuticas que as contem e de seus intermediarios
PT95972A (pt)	1991-09-13	Processo de preparacao de novos compostos de imidazoquinoxalina e de composicoes farmaceuticas que os contem
SE9004076D0 (sv)	1990-12-20	Anvaendning av 10-acetyl-1,8,9-triacetoxi-antracen som antiinflammatoriskst medel vid framstaellning av farmaceutiska och kosmetiska kompositioner
BR9501586A (pt)	1995-11-14	Polímero estabilizado contendo halogênio mistura estabilizadora uso de uma mistura estabilizadora e processo para a preparação de um polímero