PT91010A - Processo de preparacao de derivados substituidos de quinoxalina - Google Patents

Processo de preparacao de derivados substituidos de quinoxalina

Info

Publication number
PT91010A
PT91010A PT91010A PT9101089A PT91010A PT 91010 A PT91010 A PT 91010A PT 91010 A PT91010 A PT 91010A PT 9101089 A PT9101089 A PT 9101089A PT 91010 A PT91010 A PT 91010A
Authority
PT
Portugal
Prior art keywords
preparation
quinoxaline derivatives
compounds
substituted quinoxaline
hydrogen
Prior art date
Application number
PT91010A
Other languages
English (en)
Other versions
PT91010B (pt
Inventor
Jorgen Drejer
Flemming Elmelund Nielsen
Tage Honore
Poul Jacobsen
Original Assignee
Ferrosan As
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ferrosan As filed Critical Ferrosan As
Publication of PT91010A publication Critical patent/PT91010A/pt
Publication of PT91010B publication Critical patent/PT91010B/pt

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D487/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04Ortho-condensed systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D495/00Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
    • C07D495/02Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D495/04Ortho-condensed systems
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D513/00Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00
    • C07D513/02Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00 in which the condensed system contains two hetero rings
    • C07D513/04Ortho-condensed systems
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D517/00Heterocyclic compounds containing in the condensed system at least one hetero ring having selenium, tellurium, or halogen atoms as ring hetero atoms
    • C07D517/02Heterocyclic compounds containing in the condensed system at least one hetero ring having selenium, tellurium, or halogen atoms as ring hetero atoms in which the condensed system contains two hetero rings
    • C07D517/04Ortho-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Luminescent Compositions (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
PT91010A 1988-06-28 1989-06-28 Processo de preparacao de derivados substituidos de quinoxalina PT91010B (pt)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DK356788A DK160941C (da) 1988-06-28 1988-06-28 Kondenserede 2,3-dihydroxypyraziner, fremgangsmaade til deres fremstilling og farmaceutiske praeparater, hvori forbindelserne indgaar

Publications (2)

Publication Number Publication Date
PT91010A true PT91010A (pt) 1989-12-29
PT91010B PT91010B (pt) 1995-01-31

Family

ID=8124358

Family Applications (1)

Application Number Title Priority Date Filing Date
PT91010A PT91010B (pt) 1988-06-28 1989-06-28 Processo de preparacao de derivados substituidos de quinoxalina

Country Status (18)

Country Link
US (5) US4977155A (pt)
EP (1) EP0348872B1 (pt)
JP (1) JPH0248578A (pt)
KR (1) KR910000735A (pt)
AT (1) ATE95181T1 (pt)
AU (1) AU619863B2 (pt)
CA (1) CA1326670C (pt)
DE (1) DE68909513T2 (pt)
DK (1) DK160941C (pt)
ES (1) ES2059636T3 (pt)
FI (1) FI91259C (pt)
IE (1) IE64289B1 (pt)
IL (1) IL90733A (pt)
NO (1) NO169390C (pt)
NZ (1) NZ229730A (pt)
PH (1) PH27565A (pt)
PT (1) PT91010B (pt)
ZA (1) ZA894903B (pt)

Families Citing this family (27)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK716188D0 (da) * 1988-12-22 1988-12-22 Ferrosan As Quinoxalinforbindelser, deres fremstilling og anvendelse
US5153195A (en) * 1988-12-22 1992-10-06 Novo Nordisk A/S Quinoxaline compounds and their preparation and use
PT99864B (pt) 1990-12-21 1999-06-30 Schering Ag Processo para a preparacao de novas composicoes farmaceuticas contendo antagonistas de receptor de quisqualato
US5153196A (en) * 1991-06-05 1992-10-06 Eli Lilly And Company Excitatory amino acid receptor antagonists and methods for the use thereof
US5196421A (en) * 1991-06-05 1993-03-23 Eli Lilly And Company Excitatory amino acid receptor antagonists in methods for the use thereof
DK162491D0 (da) * 1991-09-20 1991-09-20 Novo Nordisk As Heterocycliske forbindelser, deres fremstilling og farmaceutiske praeparater indeholdende forbindelserne
WO1994000124A1 (en) * 1992-06-22 1994-01-06 Eckard Weber Glycine receptor antagonists and the use thereof
ATE157977T1 (de) 1992-10-13 1997-09-15 Warner Lambert Co Chinoxalinderivate als eaa antagonisten
DE4310523A1 (de) * 1993-03-31 1994-10-06 Basf Ag Imidazolo-chinoxalinone zur Behandlung zentralnervöser Erkrankungen
US5631373A (en) * 1993-11-05 1997-05-20 State Of Oregon, Acting By And Through The Oregon State Board Of Higher Education, Acting For And On Behalf Of The Oregon Health Sciences University And The University Of Oregon, Eugene Oregon Alkyl, azido, alkoxy, and fluoro-substituted and fused quinoxalinediones
US5576323A (en) * 1993-12-03 1996-11-19 Eli Lilly And Company Excitatory amino acid receptor antagonists
AU688459B2 (en) * 1994-04-08 1998-03-12 Shionogi & Co., Ltd. Oxopyridinylquinoxaline derivative
US5476851A (en) * 1994-09-08 1995-12-19 Rhone-Poulenc Rorer Pharmaceuticals, Inc. Pyrazolo[3,4-g]quinoxaline compounds which inhibit PDGF receptor protein tyrosine kinase
US5719153A (en) * 1995-08-15 1998-02-17 American Home Products Corporation 5H,8H-2-oxa-1,3,5,8-tetraaza-cyclopenta b!-naphthalene-6,7-diones
US5824662A (en) 1996-09-27 1998-10-20 Guilford Pharmaceuticals Inc. Treatment of global and focal ischemia using naaladase inhibitors
US6017903A (en) 1996-09-27 2000-01-25 Guilford Pharmaceuticals Inc. Pharmaceutical compositions and methods of treating a glutamate abnormality and effecting a neuronal activity in an animal using NAALADase inhibitors
PL332413A1 (en) 1996-09-27 1999-09-13 Guilford Pharm Inc Compositions containing inhibitors of naaladase as well as methods of treating glutamatic anomaly and influencing neuronic functions among animals
BR9807083A (pt) 1997-01-23 2000-04-18 Smithkline Beckman Corp Antagonistas ao receptor de il-8
US6288075B1 (en) 1998-02-26 2001-09-11 Rhone-Poulenc Rorer S.A. Thiazolo[5,4,3-ij]quinolines, preparation and medicines containing the same
FR2760237B1 (fr) * 1997-02-28 1999-04-16 Rhone Poulenc Rorer Sa Thiazolobenzoheterocycles, leur preparation et les medicaments les contenant
FR2766487B1 (fr) * 1997-07-28 1999-08-27 Rhone Poulenc Rorer Sa Thiazolobenzoheterocycles, leur preparation et les medicaments les contenant
WO1999046267A1 (en) * 1998-03-12 1999-09-16 Novo Nordisk A/S Modulators of protein tyrosine phosphatases (ptpases)
US6262044B1 (en) 1998-03-12 2001-07-17 Novo Nordisk A/S Modulators of protein tyrosine phosphatases (PTPASES)
JP2009286778A (ja) * 2008-04-30 2009-12-10 Sumitomo Chemical Co Ltd tert−ブチル3−アミノピペリジン−1−カルボキシレートの製造方法およびその中間体
EP2338492A1 (en) 2009-12-24 2011-06-29 Universidad del Pais Vasco Methods and compositions for the treatment of alzheimer
EP3427729A1 (en) 2017-07-13 2019-01-16 Paris Sciences et Lettres - Quartier Latin Probenecid for use in treating epileptic diseases, disorders or conditions
CN113549087B (zh) * 2020-04-26 2025-09-12 北京鼎材科技有限公司 一种化合物及其应用

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA1246578A (en) * 1982-03-29 1988-12-13 John H. Musser 2-oxo-1,3-oxazolo[4,5]quinolines useful as anti-allergy agents
DK146787A (da) * 1987-03-23 1988-09-24 Ferrosan Heterocykliske forbindelser, deres fremstilling og anvendelse

Also Published As

Publication number Publication date
NZ229730A (en) 1991-07-26
AU619863B2 (en) 1992-02-06
ZA894903B (en) 1990-03-28
EP0348872B1 (en) 1993-09-29
AU3707789A (en) 1990-01-04
PT91010B (pt) 1995-01-31
JPH0248578A (ja) 1990-02-19
NO169390C (no) 1992-06-17
DK356788D0 (da) 1988-06-28
DK160941C (da) 1991-10-21
CA1326670C (en) 1994-02-01
FI91259C (fi) 1994-06-10
IE892008L (en) 1989-12-28
NO892680L (no) 1989-12-29
US5079250A (en) 1992-01-07
PH27565A (en) 1993-08-18
US5109001A (en) 1992-04-28
NO169390B (no) 1992-03-09
US5057516A (en) 1991-10-15
DE68909513D1 (de) 1993-11-04
ATE95181T1 (de) 1993-10-15
DK356788A (da) 1990-03-21
FI893170A0 (fi) 1989-06-28
DK160941B (da) 1991-05-06
FI91259B (fi) 1994-02-28
IE64289B1 (en) 1995-07-26
NO892680D0 (no) 1989-06-27
DE68909513T2 (de) 1994-01-20
US5075306A (en) 1991-12-24
IL90733A (en) 1994-02-27
IL90733A0 (en) 1990-01-18
EP0348872A1 (en) 1990-01-03
FI893170L (fi) 1989-12-29
ES2059636T3 (es) 1994-11-16
KR910000735A (ko) 1991-01-30
US4977155A (en) 1990-12-11

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Legal Events

Date Code Title Description
FG3A Patent granted, date of granting

Effective date: 19940714

MM3A Annulment or lapse

Free format text: LAPSE DUE TO NON-PAYMENT OF FEES

Effective date: 19990131