PT91010A - Processo de preparacao de derivados substituidos de quinoxalina - Google Patents
Processo de preparacao de derivados substituidos de quinoxalinaInfo
- Publication number
- PT91010A PT91010A PT91010A PT9101089A PT91010A PT 91010 A PT91010 A PT 91010A PT 91010 A PT91010 A PT 91010A PT 9101089 A PT9101089 A PT 9101089A PT 91010 A PT91010 A PT 91010A
- Authority
- PT
- Portugal
- Prior art keywords
- preparation
- quinoxaline derivatives
- compounds
- substituted quinoxaline
- hydrogen
- Prior art date
Links
- XSCHRSMBECNVNS-UHFFFAOYSA-N quinoxaline Chemical class N1=CC=NC2=CC=CC=C21 XSCHRSMBECNVNS-UHFFFAOYSA-N 0.000 title 1
- 150000001875 compounds Chemical class 0.000 abstract 2
- 150000002431 hydrogen Chemical class 0.000 abstract 2
- 229910052739 hydrogen Inorganic materials 0.000 abstract 2
- 239000001257 hydrogen Substances 0.000 abstract 2
- -1 Heterocyclic dihydroxyquinoxaline compounds Chemical class 0.000 abstract 1
- 229910006074 SO2NH2 Inorganic materials 0.000 abstract 1
- 125000000217 alkyl group Chemical group 0.000 abstract 1
- 230000002964 excitative effect Effects 0.000 abstract 1
- 229910052736 halogen Inorganic materials 0.000 abstract 1
- 150000002367 halogens Chemical class 0.000 abstract 1
- 208000013403 hyperactivity Diseases 0.000 abstract 1
- 239000002858 neurotransmitter agent Substances 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
- 125000000565 sulfonamide group Chemical group 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
- C07D495/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
- C07D495/04—Ortho-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D513/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00
- C07D513/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00 in which the condensed system contains two hetero rings
- C07D513/04—Ortho-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D517/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having selenium, tellurium, or halogen atoms as ring hetero atoms
- C07D517/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having selenium, tellurium, or halogen atoms as ring hetero atoms in which the condensed system contains two hetero rings
- C07D517/04—Ortho-condensed systems
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Engineering & Computer Science (AREA)
- Public Health (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Plural Heterocyclic Compounds (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
- Luminescent Compositions (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DK356788A DK160941C (da) | 1988-06-28 | 1988-06-28 | Kondenserede 2,3-dihydroxypyraziner, fremgangsmaade til deres fremstilling og farmaceutiske praeparater, hvori forbindelserne indgaar |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| PT91010A true PT91010A (pt) | 1989-12-29 |
| PT91010B PT91010B (pt) | 1995-01-31 |
Family
ID=8124358
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PT91010A PT91010B (pt) | 1988-06-28 | 1989-06-28 | Processo de preparacao de derivados substituidos de quinoxalina |
Country Status (18)
| Country | Link |
|---|---|
| US (5) | US4977155A (pt) |
| EP (1) | EP0348872B1 (pt) |
| JP (1) | JPH0248578A (pt) |
| KR (1) | KR910000735A (pt) |
| AT (1) | ATE95181T1 (pt) |
| AU (1) | AU619863B2 (pt) |
| CA (1) | CA1326670C (pt) |
| DE (1) | DE68909513T2 (pt) |
| DK (1) | DK160941C (pt) |
| ES (1) | ES2059636T3 (pt) |
| FI (1) | FI91259C (pt) |
| IE (1) | IE64289B1 (pt) |
| IL (1) | IL90733A (pt) |
| NO (1) | NO169390C (pt) |
| NZ (1) | NZ229730A (pt) |
| PH (1) | PH27565A (pt) |
| PT (1) | PT91010B (pt) |
| ZA (1) | ZA894903B (pt) |
Families Citing this family (27)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DK716188D0 (da) * | 1988-12-22 | 1988-12-22 | Ferrosan As | Quinoxalinforbindelser, deres fremstilling og anvendelse |
| US5153195A (en) * | 1988-12-22 | 1992-10-06 | Novo Nordisk A/S | Quinoxaline compounds and their preparation and use |
| PT99864B (pt) | 1990-12-21 | 1999-06-30 | Schering Ag | Processo para a preparacao de novas composicoes farmaceuticas contendo antagonistas de receptor de quisqualato |
| US5196421A (en) * | 1991-06-05 | 1993-03-23 | Eli Lilly And Company | Excitatory amino acid receptor antagonists in methods for the use thereof |
| US5153196A (en) * | 1991-06-05 | 1992-10-06 | Eli Lilly And Company | Excitatory amino acid receptor antagonists and methods for the use thereof |
| DK162491D0 (da) * | 1991-09-20 | 1991-09-20 | Novo Nordisk As | Heterocycliske forbindelser, deres fremstilling og farmaceutiske praeparater indeholdende forbindelserne |
| KR100304017B1 (ko) * | 1992-06-22 | 2001-11-22 | 추후제출 | 글리신수용체길항물질및이의용도 |
| EP0664807B1 (en) | 1992-10-13 | 1997-09-10 | Warner-Lambert Company | Quinoxalinedione derivatives as eaa antagonists |
| DE4310523A1 (de) * | 1993-03-31 | 1994-10-06 | Basf Ag | Imidazolo-chinoxalinone zur Behandlung zentralnervöser Erkrankungen |
| US5631373A (en) * | 1993-11-05 | 1997-05-20 | State Of Oregon, Acting By And Through The Oregon State Board Of Higher Education, Acting For And On Behalf Of The Oregon Health Sciences University And The University Of Oregon, Eugene Oregon | Alkyl, azido, alkoxy, and fluoro-substituted and fused quinoxalinediones |
| US5576323A (en) * | 1993-12-03 | 1996-11-19 | Eli Lilly And Company | Excitatory amino acid receptor antagonists |
| AU688459B2 (en) * | 1994-04-08 | 1998-03-12 | Shionogi & Co., Ltd. | Oxopyridinylquinoxaline derivative |
| US5476851A (en) * | 1994-09-08 | 1995-12-19 | Rhone-Poulenc Rorer Pharmaceuticals, Inc. | Pyrazolo[3,4-g]quinoxaline compounds which inhibit PDGF receptor protein tyrosine kinase |
| US5719153A (en) * | 1995-08-15 | 1998-02-17 | American Home Products Corporation | 5H,8H-2-oxa-1,3,5,8-tetraaza-cyclopenta b!-naphthalene-6,7-diones |
| US5824662A (en) | 1996-09-27 | 1998-10-20 | Guilford Pharmaceuticals Inc. | Treatment of global and focal ischemia using naaladase inhibitors |
| US6017903A (en) | 1996-09-27 | 2000-01-25 | Guilford Pharmaceuticals Inc. | Pharmaceutical compositions and methods of treating a glutamate abnormality and effecting a neuronal activity in an animal using NAALADase inhibitors |
| PL332413A1 (en) | 1996-09-27 | 1999-09-13 | Guilford Pharm Inc | Compositions containing inhibitors of naaladase as well as methods of treating glutamatic anomaly and influencing neuronic functions among animals |
| BR9807083A (pt) | 1997-01-23 | 2000-04-18 | Smithkline Beckman Corp | Antagonistas ao receptor de il-8 |
| FR2760237B1 (fr) * | 1997-02-28 | 1999-04-16 | Rhone Poulenc Rorer Sa | Thiazolobenzoheterocycles, leur preparation et les medicaments les contenant |
| US6288075B1 (en) | 1998-02-26 | 2001-09-11 | Rhone-Poulenc Rorer S.A. | Thiazolo[5,4,3-ij]quinolines, preparation and medicines containing the same |
| FR2766487B1 (fr) * | 1997-07-28 | 1999-08-27 | Rhone Poulenc Rorer Sa | Thiazolobenzoheterocycles, leur preparation et les medicaments les contenant |
| US6262044B1 (en) | 1998-03-12 | 2001-07-17 | Novo Nordisk A/S | Modulators of protein tyrosine phosphatases (PTPASES) |
| WO1999046267A1 (en) * | 1998-03-12 | 1999-09-16 | Novo Nordisk A/S | Modulators of protein tyrosine phosphatases (ptpases) |
| WO2009133778A1 (ja) * | 2008-04-30 | 2009-11-05 | 住友化学株式会社 | tert-ブチル 3-アミノピペリジン-1-カルボキシレートの製造方法およびその中間体 |
| EP2338492A1 (en) | 2009-12-24 | 2011-06-29 | Universidad del Pais Vasco | Methods and compositions for the treatment of alzheimer |
| EP3427729A1 (en) | 2017-07-13 | 2019-01-16 | Paris Sciences et Lettres - Quartier Latin | Probenecid for use in treating epileptic diseases, disorders or conditions |
| CN113549087B (zh) * | 2020-04-26 | 2025-09-12 | 北京鼎材科技有限公司 | 一种化合物及其应用 |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA1246578A (en) * | 1982-03-29 | 1988-12-13 | John H. Musser | 2-oxo-1,3-oxazolo[4,5]quinolines useful as anti-allergy agents |
| DK146787A (da) * | 1987-03-23 | 1988-09-24 | Ferrosan | Heterocykliske forbindelser, deres fremstilling og anvendelse |
-
1988
- 1988-06-28 DK DK356788A patent/DK160941C/da not_active IP Right Cessation
-
1989
- 1989-06-21 IE IE200889A patent/IE64289B1/en not_active IP Right Cessation
- 1989-06-22 US US07/369,762 patent/US4977155A/en not_active Expired - Fee Related
- 1989-06-23 CA CA000603702A patent/CA1326670C/en not_active Expired - Fee Related
- 1989-06-23 IL IL9073389A patent/IL90733A/en not_active IP Right Cessation
- 1989-06-26 ES ES89111622T patent/ES2059636T3/es not_active Expired - Lifetime
- 1989-06-26 EP EP89111622A patent/EP0348872B1/en not_active Expired - Lifetime
- 1989-06-26 AT AT89111622T patent/ATE95181T1/de active
- 1989-06-26 DE DE89111622T patent/DE68909513T2/de not_active Expired - Fee Related
- 1989-06-27 NZ NZ229730A patent/NZ229730A/en unknown
- 1989-06-27 NO NO892680A patent/NO169390C/no unknown
- 1989-06-27 AU AU37077/89A patent/AU619863B2/en not_active Ceased
- 1989-06-28 FI FI893170A patent/FI91259C/fi not_active IP Right Cessation
- 1989-06-28 KR KR1019890008933A patent/KR910000735A/ko not_active Ceased
- 1989-06-28 PT PT91010A patent/PT91010B/pt not_active IP Right Cessation
- 1989-06-28 JP JP1164091A patent/JPH0248578A/ja active Pending
- 1989-06-28 ZA ZA894903A patent/ZA894903B/xx unknown
- 1989-06-28 PH PH38872A patent/PH27565A/en unknown
-
1990
- 1990-08-20 US US07/570,019 patent/US5075306A/en not_active Expired - Fee Related
- 1990-08-22 US US07/570,819 patent/US5109001A/en not_active Expired - Fee Related
- 1990-08-22 US US07/570,903 patent/US5057516A/en not_active Expired - Fee Related
- 1990-08-23 US US07/572,172 patent/US5079250A/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| IE64289B1 (en) | 1995-07-26 |
| EP0348872B1 (en) | 1993-09-29 |
| US5079250A (en) | 1992-01-07 |
| US5057516A (en) | 1991-10-15 |
| KR910000735A (ko) | 1991-01-30 |
| FI893170L (fi) | 1989-12-29 |
| DK160941C (da) | 1991-10-21 |
| AU3707789A (en) | 1990-01-04 |
| PT91010B (pt) | 1995-01-31 |
| CA1326670C (en) | 1994-02-01 |
| FI893170A0 (fi) | 1989-06-28 |
| DK356788A (da) | 1990-03-21 |
| ZA894903B (en) | 1990-03-28 |
| DE68909513T2 (de) | 1994-01-20 |
| EP0348872A1 (en) | 1990-01-03 |
| US4977155A (en) | 1990-12-11 |
| PH27565A (en) | 1993-08-18 |
| IL90733A0 (en) | 1990-01-18 |
| NO892680L (no) | 1989-12-29 |
| DE68909513D1 (de) | 1993-11-04 |
| NO169390C (no) | 1992-06-17 |
| DK356788D0 (da) | 1988-06-28 |
| AU619863B2 (en) | 1992-02-06 |
| FI91259C (fi) | 1994-06-10 |
| US5075306A (en) | 1991-12-24 |
| ES2059636T3 (es) | 1994-11-16 |
| US5109001A (en) | 1992-04-28 |
| JPH0248578A (ja) | 1990-02-19 |
| NZ229730A (en) | 1991-07-26 |
| NO169390B (no) | 1992-03-09 |
| ATE95181T1 (de) | 1993-10-15 |
| IL90733A (en) | 1994-02-27 |
| FI91259B (fi) | 1994-02-28 |
| DK160941B (da) | 1991-05-06 |
| IE892008L (en) | 1989-12-28 |
| NO892680D0 (no) | 1989-06-27 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FG3A | Patent granted, date of granting |
Effective date: 19940714 |
|
| MM3A | Annulment or lapse |
Free format text: LAPSE DUE TO NON-PAYMENT OF FEES Effective date: 19990131 |