PT91323A - Processo para a preparacao de glicosidos antraciclinicos, de antraciclinonas 4-substituidas intermedias e de composicoes farmaceuticas que os contem - Google Patents

Processo para a preparacao de glicosidos antraciclinicos, de antraciclinonas 4-substituidas intermedias e de composicoes farmaceuticas que os contem

Info

Publication number
PT91323A
PT91323A PT91323A PT9132389A PT91323A PT 91323 A PT91323 A PT 91323A PT 91323 A PT91323 A PT 91323A PT 9132389 A PT9132389 A PT 9132389A PT 91323 A PT91323 A PT 91323A
Authority
PT
Portugal
Prior art keywords
preparation
substituted
glycosides
anthraciclinones
ancericyclic
Prior art date
Application number
PT91323A
Other languages
English (en)
Other versions
PT91323B (pt
Inventor
Walter Cabri
Silvia De Bernardinis
Franco Francalanci
Sergio Penco
Original Assignee
Erba Farmitalia
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Erba Farmitalia filed Critical Erba Farmitalia
Publication of PT91323A publication Critical patent/PT91323A/pt
Publication of PT91323B publication Critical patent/PT91323B/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C07H15/20—Carbocyclic rings
    • C07H15/24—Condensed ring systems having three or more rings
    • C07H15/252—Naphthacene radicals, e.g. daunomycins, adriamycins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Oncology (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Communicable Diseases (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
PT91323A 1988-07-29 1989-07-31 Processo para a preparacao de glicosidos antraciclinicos, de antraciclinonas 4-substituidas intermedias e de composicoes farmaceuticas que os contem PT91323B (pt)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB888818167A GB8818167D0 (en) 1988-07-29 1988-07-29 Novel 4-substituted anthracyclinones & process for their preparation

Publications (2)

Publication Number Publication Date
PT91323A true PT91323A (pt) 1990-02-08
PT91323B PT91323B (pt) 1995-03-01

Family

ID=10641362

Family Applications (1)

Application Number Title Priority Date Filing Date
PT91323A PT91323B (pt) 1988-07-29 1989-07-31 Processo para a preparacao de glicosidos antraciclinicos, de antraciclinonas 4-substituidas intermedias e de composicoes farmaceuticas que os contem

Country Status (21)

Country Link
US (1) US5218130A (pt)
EP (1) EP0354995B1 (pt)
JP (1) JP2749923B2 (pt)
KR (1) KR900701811A (pt)
AT (1) ATE71105T1 (pt)
AU (1) AU619331B2 (pt)
CA (1) CA1337985C (pt)
DE (1) DE68900638D1 (pt)
DK (1) DK14691A (pt)
ES (1) ES2045282T3 (pt)
FI (1) FI91762C (pt)
GB (1) GB8818167D0 (pt)
GR (1) GR3003511T3 (pt)
HU (1) HU208106B (pt)
IE (1) IE62000B1 (pt)
IL (1) IL91100A (pt)
NZ (1) NZ230051A (pt)
PT (1) PT91323B (pt)
RU (1) RU2071463C1 (pt)
WO (1) WO1990001490A1 (pt)
ZA (1) ZA895729B (pt)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8904794D0 (en) * 1989-03-02 1989-04-12 Erba Carlo Spa Process for preparing anthracyclinones
GB9019934D0 (en) * 1990-09-12 1990-10-24 Erba Carlo Spa 2-hydroxy-and 2-acyloxy-4-morpholinyl anthracyclines
GB9028105D0 (en) * 1990-12-27 1991-02-13 Erba Carlo Spa Process for the preparation of substituted benzofuran derivatives
US7053191B2 (en) * 2003-05-21 2006-05-30 Solux Corporation Method of preparing 4-R-substituted 4-demethoxydaunorubicin
CN100379749C (zh) * 2003-05-21 2008-04-09 獀洛克斯股份有限公司 4-r-取代的4-去甲氧基柔红霉素的制备方法
US8357785B2 (en) * 2008-01-08 2013-01-22 Solux Corporation Method of aralkylation of 4′-hydroxyl group of anthracylins
US8846882B2 (en) 2011-04-29 2014-09-30 Synbias Pharma Ag Method of producing 4-demethoxydaunorubicin

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1467383A (en) * 1974-06-12 1977-03-16 Farmaceutici Italia Daunomycin analogues
GB2182926B (en) * 1985-11-19 1989-10-04 Erba Farmitalia Nitro anthracyclines, process for their preparation and use thereof
GB8617742D0 (en) * 1986-07-21 1986-08-28 Erba Farmitalia 6-amino anthracyclines
NZ224252A (en) * 1987-04-21 1991-09-25 Erba Carlo Spa An anthracycline glycoside and its preparation
GB2212154B (en) * 1987-11-10 1991-03-27 Erba Carlo Spa New 4-demethoxy anthracycline derivatives
GB8803076D0 (en) * 1988-02-10 1988-03-09 Erba Carlo Spa 3'-deamino-4'-deoxy-4'-amino anthracyclines

Also Published As

Publication number Publication date
ES2045282T3 (es) 1994-01-16
AU619331B2 (en) 1992-01-23
DK14691A (da) 1991-03-26
HU894607D0 (en) 1991-08-28
EP0354995A1 (en) 1990-02-21
FI91762B (fi) 1994-04-29
RU2071463C1 (ru) 1997-01-10
DK14691D0 (da) 1991-01-28
AU3983689A (en) 1990-03-05
NZ230051A (en) 1990-11-27
US5218130A (en) 1993-06-08
JP2749923B2 (ja) 1998-05-13
IE62000B1 (en) 1994-12-14
IL91100A (en) 1994-06-24
ATE71105T1 (de) 1992-01-15
EP0354995B1 (en) 1992-01-02
CA1337985C (en) 1996-01-23
ZA895729B (en) 1990-05-30
WO1990001490A1 (en) 1990-02-22
FI91762C (fi) 1994-08-10
IE892458L (en) 1990-01-29
FI910412A0 (fi) 1991-01-28
PT91323B (pt) 1995-03-01
JPH04500956A (ja) 1992-02-20
HU208106B (en) 1993-08-30
DE68900638D1 (de) 1992-02-13
IL91100A0 (en) 1990-03-19
HUT56847A (en) 1991-10-28
GB8818167D0 (en) 1988-09-01
GR3003511T3 (pt) 1993-03-16
KR900701811A (ko) 1990-12-04

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Legal Events

Date Code Title Description
FG3A Patent granted, date of granting

Effective date: 19940817

MM3A Annulment or lapse

Free format text: LAPSE DUE TO NON-PAYMENT OF FEES

Effective date: 19990228