PT91468A - Processo para a preparacao de um novo antibiotico mersacidina e de composicoes farmaceuticas que o contem - Google Patents

Processo para a preparacao de um novo antibiotico mersacidina e de composicoes farmaceuticas que o contem

Info

Publication number: PT91468A
Authority: PT; Portugal
Prior art keywords: antibiotic; mersacidine; preparing; new; pharmaceutical compositions
Prior art date: 1988-08-17

Application number

PT91468A

Other languages

English (en)

Other versions

PT91468B (pt

Inventor

Gerhard Seibert

Sugata Chatterjee

Volker Teetz

Herbert Kogler

Hans-Wolfram Fehlhaber

Bimal Naresh Ganguli

Richard Helmut Rupp

Deepak Kumar Chatterjee

Sukumar Chatterjee

Ranjendra Kumar Hariprasa Jani

Original Assignee

Hoechst Ag

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1988-08-17

Filing date

1989-08-17

Publication date

1990-03-08

1989-08-17 Application filed by Hoechst Ag filed Critical Hoechst Ag

1990-03-08 Publication of PT91468A publication Critical patent/PT91468A/pt

1995-05-04 Publication of PT91468B publication Critical patent/PT91468B/pt

Links

230000003115 biocidal effect Effects 0.000 title abstract 2
239000008194 pharmaceutical composition Substances 0.000 title 1
108010069514 Cyclic Peptides Proteins 0.000 abstract 1
102000001189 Cyclic Peptides Human genes 0.000 abstract 1
JSWKNDSDVHJUKY-CYGWNLPQSA-N mersacidin Chemical compound C([C@@H](C(=O)N[C@@H]1[C@H](C)SC[C@H](NC(=O)[C@H](C(C)C)NC(=O)CNC(=O)CNC(=O)CNC(=O)CNC(=O)[C@@H]2CCCN2C(=O)[C@H](CC(C)C)NC1=O)C(=O)N[C@@H]1[C@H](C)SC[C@H]2C(=O)N[C@H](C(N/C=C/S[C@@H](C)C(NC(=O)[C@H](CC(C)C)NC1=O)C(=O)NC(=C)C(=O)N[C@@H](CCC(O)=O)C(=O)N2)=O)[C@H](C)CC)NC(=O)[C@H]1[C@@H](SC[C@H](N)C(=O)N1)C)C1=CC=CC=C1 JSWKNDSDVHJUKY-CYGWNLPQSA-N 0.000 abstract 1
108010067215 mersacidin Proteins 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
- C07K7/04—Linear peptides containing only normal peptide links
- C07K7/08—Linear peptides containing only normal peptide links having 12 to 20 amino acids
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P21/00—Preparation of peptides or proteins
- C12P21/02—Preparation of peptides or proteins having a known sequence of two or more amino acids, e.g. glutathione
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
- C07K7/50—Cyclic peptides containing at least one abnormal peptide link
- C07K7/54—Cyclic peptides containing at least one abnormal peptide link with at least one abnormal peptide link in the ring
- C07K7/56—Cyclic peptides containing at least one abnormal peptide link with at least one abnormal peptide link in the ring the cyclisation not occurring through 2,4-diamino-butanoic acid
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S435/00—Chemistry: molecular biology and microbiology
- Y10S435/8215—Microorganisms
- Y10S435/822—Microorganisms using bacteria or actinomycetales
- Y10S435/832—Bacillus
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S930/00—Peptide or protein sequence
- Y10S930/01—Peptide or protein sequence
- Y10S930/19—Antibiotic

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Life Sciences & Earth Sciences (AREA)
Health & Medical Sciences (AREA)
General Health & Medical Sciences (AREA)
Molecular Biology (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Engineering & Computer Science (AREA)
Zoology (AREA)
Genetics & Genomics (AREA)
Wood Science & Technology (AREA)
Biochemistry (AREA)
Medicinal Chemistry (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Bioinformatics & Cheminformatics (AREA)
General Engineering & Computer Science (AREA)
Biophysics (AREA)
Biotechnology (AREA)
Microbiology (AREA)
Public Health (AREA)
Communicable Diseases (AREA)
Veterinary Medicine (AREA)
Oncology (AREA)
Animal Behavior & Ethology (AREA)
Pharmacology & Pharmacy (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Preparation Of Compounds By Using Micro-Organisms (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Peptides Or Proteins (AREA)
Saccharide Compounds (AREA)
Micro-Organisms Or Cultivation Processes Thereof (AREA)
Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Cephalosporin Compounds (AREA)

PT91468A 1988-08-17 1989-08-17 Processo para a preparacao de um novo antibiotico mersacidina e de composicoes farmaceuticas que o contem PT91468B (pt)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
DE3827868A DE3827868A1 (de)	1988-08-17	1988-08-17	Ein neues antibiotikum, mersacidin, ein verfahren zu seiner herstellung und seine verwendung als arzneimittel

Publications (2)

Publication Number	Publication Date
PT91468A true PT91468A (pt)	1990-03-08
PT91468B PT91468B (pt)	1995-05-04

Family

ID=6361001

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
PT91468A PT91468B (pt)	1988-08-17	1989-08-17	Processo para a preparacao de um novo antibiotico mersacidina e de composicoes farmaceuticas que o contem

Country Status (20)

Country	Link
US (1)	US5112806A (pt)
EP (1)	EP0362520B1 (pt)
JP (1)	JP2892699B2 (pt)
KR (1)	KR0139628B1 (pt)
AT (1)	ATE113296T1 (pt)
AU (1)	AU613228B2 (pt)
CA (1)	CA1338171C (pt)
DE (2)	DE3827868A1 (pt)
DK (1)	DK175121B1 (pt)
ES (1)	ES2064398T3 (pt)
FI (1)	FI94648C (pt)
HU (1)	HU203906B (pt)
IE (1)	IE64706B1 (pt)
IL (1)	IL91317A0 (pt)
IN (1)	IN167138B (pt)
NO (1)	NO174517B (pt)
NZ (1)	NZ230303A (pt)
PH (1)	PH27179A (pt)
PT (1)	PT91468B (pt)
ZA (1)	ZA896245B (pt)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
EP0700998B1 (en) *	1994-09-12	2003-11-26	Aventis Pharma Deutschland GmbH	Recombinant mersacidin and a method for production
US5910479A (en) *	1996-10-18	1999-06-08	Ambi Inc.	Method for the treatment of Streptococcus pneumoniae infection
US6861236B2 (en) *	2002-05-24	2005-03-01	Applied Nanosystems B.V.	Export and modification of (poly)peptides in the lantibiotic way
GB0406870D0 (en)	2004-03-26	2004-04-28	Novacta Biosystems Ltd	Improvements relating to the production of lantibiotics
JP2009509519A (ja) *	2005-09-27	2009-03-12	ノヴァクタバイオシステムズリミティッド	ランチビオティックメルサシジンの変種およびそれらの使用
GB0600928D0 (en)	2006-01-17	2006-02-22	Novacta Biosystems Ltd	Improvements relating to lantibiotics
GB0714029D0 (en) *	2007-07-18	2007-08-29	Novacta Biosystems Ltd	Lantibiotic-based compounds having antimicrobial activity
GB0714030D0 (en) *	2007-07-18	2007-08-29	Novacta Biosystems Ltd	The use of type-B lantibiotic-based compounds having antimicrobial activity
SI2387580T1 (sl)	2009-01-14	2014-11-28	Novacta Biosystems Limited	Deoksiaktagardinski derivati
MX2011008043A (es)	2009-02-04	2011-08-17	Novacta Biosystems Ltd	Derivados de actagardina.
GB201001688D0 (en)	2010-02-02	2010-03-17	Novacta Biosystems Ltd	Compounds
GB201013513D0 (en)	2010-08-11	2010-09-22	Novacta Biosystems Ltd	Formulations
KR102582570B1 (ko) *	2021-03-19	2023-09-22	한국생명공학연구원	유박테리움 칼란데리, 이의 배양액 또는 이의 배양액 추출물을 유효성분으로 포함하는 암 예방 또는 치료용 조성물
EP4404946A4 (en) *	2021-09-22	2026-01-07	Biomedit Inc	METHOD FOR INHIBITING DISEASES SURRIDATED BY RESPIRATORY VIRUSES

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US4493796A (en) *	1980-09-12	1985-01-15	Board Of Trustees, Univ. Of Ill.	Didemnins A, B, C, and derivatives thereof, as antiviral agents
JPS61134398A (ja) *	1984-12-06	1986-06-21	Microbial Chem Res Found	新生理活性物質プリパスタチン及びその製造法

1988
- 1988-07-04 IN IN193/BOM/88A patent/IN167138B/en unknown
- 1988-08-17 DE DE3827868A patent/DE3827868A1/de not_active Withdrawn
1989
- 1989-08-14 EP EP89114990A patent/EP0362520B1/de not_active Expired - Lifetime
- 1989-08-14 ES ES89114990T patent/ES2064398T3/es not_active Expired - Lifetime
- 1989-08-14 AT AT89114990T patent/ATE113296T1/de not_active IP Right Cessation
- 1989-08-14 DE DE58908558T patent/DE58908558D1/de not_active Expired - Lifetime
- 1989-08-15 FI FI893842A patent/FI94648C/fi active IP Right Grant
- 1989-08-15 US US07/393,953 patent/US5112806A/en not_active Expired - Lifetime
- 1989-08-15 PH PH39098A patent/PH27179A/en unknown
- 1989-08-15 IL IL91317A patent/IL91317A0/xx unknown
- 1989-08-15 NZ NZ230303A patent/NZ230303A/en unknown
- 1989-08-16 IE IE263889A patent/IE64706B1/en not_active IP Right Cessation
- 1989-08-16 CA CA000608500A patent/CA1338171C/en not_active Expired - Lifetime
- 1989-08-16 ZA ZA896245A patent/ZA896245B/xx unknown
- 1989-08-16 NO NO893288A patent/NO174517B/no not_active IP Right Cessation
- 1989-08-16 JP JP1210228A patent/JP2892699B2/ja not_active Expired - Lifetime
- 1989-08-16 HU HU894215A patent/HU203906B/hu unknown
- 1989-08-16 AU AU39966/89A patent/AU613228B2/en not_active Expired
- 1989-08-16 DK DK198904037A patent/DK175121B1/da not_active IP Right Cessation
- 1989-08-17 PT PT91468A patent/PT91468B/pt not_active IP Right Cessation
- 1989-08-17 KR KR1019890011679A patent/KR0139628B1/ko not_active Expired - Lifetime

Also Published As

Publication number	Publication date
US5112806A (en)	1992-05-12
EP0362520B1 (de)	1994-10-26
NZ230303A (en)	1992-06-25
EP0362520A2 (de)	1990-04-11
KR0139628B1 (ko)	1998-07-01
IN167138B (pt)	1990-09-01
NO174517C (pt)	1994-05-18
HUT55054A (en)	1991-04-29
FI893842A7 (fi)	1990-02-18
NO174517B (no)	1994-02-07
IE892638L (en)	1990-02-17
DE58908558D1 (de)	1994-12-01
EP0362520A3 (de)	1991-10-23
JPH02142800A (ja)	1990-05-31
ES2064398T3 (es)	1995-02-01
IE64706B1 (en)	1995-08-23
DK403789A (da)	1990-02-18
KR900003206A (ko)	1990-03-26
NO893288L (no)	1990-02-19
FI893842A0 (fi)	1989-08-15
JP2892699B2 (ja)	1999-05-17
AU613228B2 (en)	1991-07-25
ATE113296T1 (de)	1994-11-15
ZA896245B (en)	1990-04-25
FI94648C (fi)	1995-10-10
PT91468B (pt)	1995-05-04
FI94648B (fi)	1995-06-30
NO893288D0 (no)	1989-08-16
AU3996689A (en)	1990-02-22
DK175121B1 (da)	2004-06-07
CA1338171C (en)	1996-03-19
HU203906B (en)	1991-10-28
DK403789D0 (da)	1989-08-16
DE3827868A1 (de)	1990-02-22
PH27179A (en)	1993-04-02
IL91317A0 (en)	1990-03-19

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Legal Events

Date

Code

Title

Description

1995-05-04

FG3A

Patent granted, date of granting

Effective date: 19941004

2007-06-12

PC4A

Transfer of assignment

Owner name: SANOFI-AVENTIS DEUTSCHLAND GMBH, DE

Effective date: 20070530

2009-10-14

MM4A

Annulment/lapse due to non-payment of fees, searched and examined patent

Free format text: MAXIMUM VALIDITY LIMIT REACHED

Effective date: 20091004