PT94247A - Processo para a preparacao de uma composicao farmaceutica contendo 3'-azido-3'-desoxitimidina e n-butil-desoxinojirimicina e metodo para inibir hiv utilizando-a - Google Patents

Processo para a preparacao de uma composicao farmaceutica contendo 3'-azido-3'-desoxitimidina e n-butil-desoxinojirimicina e metodo para inibir hiv utilizando-a

Info

Publication number
PT94247A
PT94247A PT94247A PT9424790A PT94247A PT 94247 A PT94247 A PT 94247A PT 94247 A PT94247 A PT 94247A PT 9424790 A PT9424790 A PT 9424790A PT 94247 A PT94247 A PT 94247A
Authority
PT
Portugal
Prior art keywords
butyl
azido
hiv
pharmaceutical composition
deoxynojyrimycin
Prior art date
Application number
PT94247A
Other languages
English (en)
Other versions
PT94247B (pt
Inventor
Martin Stanley Hirsch
Victoria Anne Johnson
Original Assignee
Searle & Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Searle & Co filed Critical Searle & Co
Publication of PT94247A publication Critical patent/PT94247A/pt
Publication of PT94247B publication Critical patent/PT94247B/pt

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A61P31/18—Antivirals for RNA viruses for HIV

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Virology (AREA)
  • Molecular Biology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Epidemiology (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • AIDS & HIV (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
PT94247A 1989-06-02 1990-06-01 Processo para a preparacao de uma composicao farmaceutica contendo 3'-azido-3'-desoxitimidina e n-butil-desoxinojirimicina e metodo para inibir hiv utilizando-a PT94247B (pt)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US07/360,439 US5011829A (en) 1989-06-02 1989-06-02 Pharmaceutical composition and method of inhibiting virus

Publications (2)

Publication Number Publication Date
PT94247A true PT94247A (pt) 1991-02-08
PT94247B PT94247B (pt) 1997-05-28

Family

ID=23417957

Family Applications (1)

Application Number Title Priority Date Filing Date
PT94247A PT94247B (pt) 1989-06-02 1990-06-01 Processo para a preparacao de uma composicao farmaceutica contendo 3'-azido-3'-desoxitimidina e n-butil-desoxinojirimicina e metodo para inibir hiv utilizando-a

Country Status (10)

Country Link
US (1) US5011829A (pt)
EP (2) EP0437554B1 (pt)
JP (1) JPH04500220A (pt)
AT (1) ATE81979T1 (pt)
CA (1) CA2030803A1 (pt)
DE (1) DE69000434T2 (pt)
DK (1) DK0437554T3 (pt)
IE (1) IE64352B1 (pt)
PT (1) PT94247B (pt)
WO (1) WO1990014830A1 (pt)

Families Citing this family (35)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5252587A (en) * 1990-04-27 1993-10-12 Merrell Dow Pharmaceuticals, Inc. N-derivatives of 1-deoxy nojirimycin
US5536732A (en) * 1990-04-27 1996-07-16 Merrell Pharmaceuticals Inc. N-derivatives of 1-deoxy nojirimycin
AU654152B2 (en) * 1990-09-06 1994-10-27 Australian National University, The Immunosuppressant composition
WO1992004055A1 (en) * 1990-09-06 1992-03-19 The Australian National University Immunosuppressant composition
SK279262B6 (sk) * 1991-05-16 1998-08-05 Glaxo Group Limited Protivírusová zmes, farmaceutický prostriedok s je
US5216168A (en) * 1992-04-01 1993-06-01 G. D. Searle & Co. 2- and 3- amino and azido derivatives of 1,5-iminosugars
US5268482A (en) * 1992-04-01 1993-12-07 G. D. Searle & Co. 2- and 3-sulfur derivatives of 1,5-iminosugars
US5342951A (en) * 1992-04-01 1994-08-30 G.D. Searle & Co. 2- and 3-sulfur derivatives of 1,5-iminosugars
US5258518A (en) * 1992-04-01 1993-11-02 G. D. Searle & Co. 2-substituted tertiary carbinol derivatives of deoxynojirimycin
US5331096A (en) * 1992-04-01 1994-07-19 G. D. Searle & Co. 2- and 3-sulfur derivatives of 1,5-iminosugars
US5206251A (en) * 1992-04-01 1993-04-27 G. D. Searle & Co. 2- and 3- amino and azido derivatives of 1,5-iminosugars
IL106717A0 (en) * 1992-08-19 1993-12-08 Schering Corp Method for inhibiting hiv replication using il-4
US5399567A (en) * 1993-05-13 1995-03-21 Monsanto Company Method of treating cholera
US6291657B1 (en) * 1993-05-13 2001-09-18 Monsanto Company Deoxygalactonojirimycin derivatives
US5798366A (en) * 1993-05-13 1998-08-25 Monsanto Company Method for treatment of CNS-involved lysosomal storage diseases
US5639598A (en) * 1994-05-19 1997-06-17 The Trustees Of The University Of Pennsylvania Method and kit for identification of antiviral agents capable of abrogating HIV Vpr-Rip-1 binding interactions
US5780220A (en) * 1994-05-19 1998-07-14 Trustees Of The University Of Pennsylvania Methods and compositions for inhibiting HIV replication
US20030100532A1 (en) 1997-02-14 2003-05-29 Gary S. Jacob Use of n-substituted-1,5-dideoxy-1,5-imino-d-glucitol compounds in combination therapy for treating hepatitis virus infections
ZA9810210B (en) 1997-11-10 1999-07-14 Searle & Co Use of alkylated iminosugars to treat multidrug resistance.
US6689759B1 (en) 1998-02-12 2004-02-10 G. D. Searle & Co. Methods of Treating hepatitis virus infections with N-substituted-1,5-dideoxy-1,5-imino-d-glucitol compounds in combination therapy
KR20010040937A (ko) 1998-02-12 2001-05-15 윌리암스 로저 에이 간염 바이러스 감염의 치료를 위한 ｎ-치환된1,5-디데옥시-1,5-이미노-ｄ-글루시톨 화합물의 용도
JP2002536407A (ja) * 1999-02-12 2002-10-29 ジー・ディー・サール・アンド・カンパニー 肝炎ウィルス感染の治療のための置換−１，５−ジデオキシ−１，５−イミノ−ｄ−グルシトール化合物の使用
CA2362785A1 (en) 1999-02-12 2001-02-08 G.D. Searle & Co. Glucamine compounds for treating hepatitis virus infections
US6569616B1 (en) * 1999-07-29 2003-05-27 Wisconsin Alumni Research Foundation Human cytomegalovirus glycoprotein O as a new drug target and subunit vaccine candidate
CN1422156A (zh) * 2000-02-14 2003-06-04 法马西亚公司 N－取代的－1,5－二脱氧－1,5－亚氨基－d－葡萄糖醇化合物在治疗肝炎病毒感染中的用途
US7884115B2 (en) * 2004-09-28 2011-02-08 Allergan, Inc. Methods and compositions for the treatment of pain and other neurological conditions
EP1896083B1 (en) 2005-05-17 2016-03-02 Amicus Therapeutics, Inc. A method for the treatment of pompe disease using 1-deoxynojirimycin and derivatives
US8097728B2 (en) * 2007-04-30 2012-01-17 Philadelphia Health & Education Corporation Iminosugar compounds with antiflavirus activity
KR20200032244A (ko) 2012-03-07 2020-03-25 아미쿠스 세라퓨틱스, 인코포레이티드 폼페병의 치료를 위한 고농도 알파-글루코시다제 조성물
PE20170906A1 (es) 2014-09-30 2017-07-12 Amicus Therapeutics Inc Alfa-glucosidasa acida muy potente con hidratos de carbono potenciados
MX394968B (es) 2015-12-30 2025-03-24 Amicus Therapeutics Inc Alfa-glucosidasa con mayor cantidad de acido para el tratamiento de la enfermedad de pompe.
WO2017173060A1 (en) 2016-03-30 2017-10-05 Amicus Therapeutics, Inc. Formulations comprising recombinant acid alpha-glucosidase
MX2018011951A (es) 2016-03-30 2019-02-13 Amicus Therapeutics Inc Metodo para seleccionar proteinas recombinantes ricas en m6p.
AU2018270925B2 (en) 2017-05-15 2025-02-20 Amicus Therapeutics, Inc. Recombinant human acid alpha-glucosidase
CN109456254B (zh) * 2018-12-06 2020-06-30 江西农业大学 1-脱氧野尻霉素-羟基查尔酮杂合体衍生物及其制备方法和应用

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4724232A (en) * 1985-03-16 1988-02-09 Burroughs Wellcome Co. Treatment of human viral infections
US4857511A (en) * 1985-09-17 1989-08-15 Burroughs Wellcome Co. Treatment of human viral infections
JPS63175354A (ja) * 1987-01-16 1988-07-19 Shin Kobe Electric Mach Co Ltd 電池用渦巻電極体の製造装置
EP0282618A1 (en) * 1987-03-18 1988-09-21 Vereniging Het Nederlands Kanker Instituut 1-Deoxynojirimycin as an anti-HIV therapeutic
US4849430A (en) * 1988-03-09 1989-07-18 Monsanto Company Method of inhibiting virus

Also Published As

Publication number Publication date
CA2030803A1 (en) 1990-12-03
DE69000434T2 (de) 1993-05-27
EP0401194A1 (en) 1990-12-05
JPH04500220A (ja) 1992-01-16
EP0437554B1 (en) 1992-11-04
EP0437554A1 (en) 1991-07-24
ATE81979T1 (de) 1992-11-15
IE64352B1 (en) 1995-07-26
US5011829A (en) 1991-04-30
IE901973L (en) 1990-12-02
DK0437554T3 (da) 1992-12-07
PT94247B (pt) 1997-05-28
DE69000434D1 (de) 1992-12-10
WO1990014830A1 (en) 1990-12-13

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Effective date: 19970224

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Effective date: 19990831