PT94952A - Processo para a preparacao de derivados peptidicos ciclicos antagonistas de neuroquinina a - Google Patents

Processo para a preparacao de derivados peptidicos ciclicos antagonistas de neuroquinina a

Info

Publication number: PT94952A
Authority: PT; Portugal
Prior art keywords: neurochinine; antigonistic; preparation; derivatives; cycle
Prior art date: 1989-08-10

Application number

PT94952A

Other languages

English (en)

Other versions

PT94952B (pt

Inventor

Scott Lee Harbeson

Stephen Hendersen Buck

Original Assignee

Merrell Dow Pharma

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1989-08-10

Filing date

1990-08-09

Publication date

1991-04-18

1990-08-09 Application filed by Merrell Dow Pharma filed Critical Merrell Dow Pharma

1991-04-18 Publication of PT94952A publication Critical patent/PT94952A/pt

1997-07-31 Publication of PT94952B publication Critical patent/PT94952B/pt

Links

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
- C07K7/04—Linear peptides containing only normal peptide links
- C07K7/22—Tachykinins, e.g. Eledoisins, Substance P; Related peptides
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
- C07K7/64—Cyclic peptides containing only normal peptide links
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/12—Antidiarrhoeals
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/08—Bronchodilators
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/02—Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Life Sciences & Earth Sciences (AREA)
Medicinal Chemistry (AREA)
General Health & Medical Sciences (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
General Chemical & Material Sciences (AREA)
Pharmacology & Pharmacy (AREA)
Chemical Kinetics & Catalysis (AREA)
Animal Behavior & Ethology (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Immunology (AREA)
Pulmonology (AREA)
Biochemistry (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Molecular Biology (AREA)
Genetics & Genomics (AREA)
Biophysics (AREA)
Biomedical Technology (AREA)
Pain & Pain Management (AREA)
Neurology (AREA)
Neurosurgery (AREA)
Urology & Nephrology (AREA)
Rheumatology (AREA)
Endocrinology (AREA)
Reproductive Health (AREA)
Dermatology (AREA)
Virology (AREA)
Heart & Thoracic Surgery (AREA)
Cardiology (AREA)
Transplantation (AREA)
Oncology (AREA)
Communicable Diseases (AREA)
Peptides Or Proteins (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

PT94952A 1989-08-10 1990-08-09 Processo para a preparacao de derivados peptidicos ciclicos antagonistas de neuroquinina a PT94952B (pt)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
US39223689A	1989-08-10	1989-08-10

Publications (2)

Publication Number	Publication Date
PT94952A true PT94952A (pt)	1991-04-18
PT94952B PT94952B (pt)	1997-07-31

Family

ID=23549831

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
PT94952A PT94952B (pt)	1989-08-10	1990-08-09	Processo para a preparacao de derivados peptidicos ciclicos antagonistas de neuroquinina a

Country Status (22)

Country	Link
US (1)	US5731286A (pt)
EP (1)	EP0412542B1 (pt)
JP (1)	JP2829779B2 (pt)
KR (1)	KR0169123B1 (pt)
CN (1)	CN1035056C (pt)
AR (1)	AR246087A1 (pt)
AT (1)	ATE132503T1 (pt)
AU (1)	AU638264B2 (pt)
CA (1)	CA2022740C (pt)
DD (1)	DD297168A5 (pt)
DE (1)	DE69024555T2 (pt)
DK (1)	DK0412542T3 (pt)
ES (1)	ES2084627T3 (pt)
FI (1)	FI95913C (pt)
GR (1)	GR3018984T3 (pt)
HU (1)	HU206729B (pt)
IE (1)	IE69382B1 (pt)
IL (1)	IL95309A (pt)
NO (1)	NO177715C (pt)
NZ (1)	NZ234814A (pt)
PT (1)	PT94952B (pt)
ZA (1)	ZA906188B (pt)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
ZA894533B (en) *	1988-06-20	1990-03-28	Merrell Dow Pharma	Neurokinin a antogonists
DE4034829A1 (de) *	1990-11-02	1992-05-07	Merck Patent Gmbh	Cyclopeptide
FR2676055B1 (fr) *	1991-05-03	1993-09-03	Sanofi Elf	Composes polycycliques amines et leurs enantiomeres, procede pour leur preparation et compositions pharmaceutiques les contenant.
US5625060A (en) *	1991-05-03	1997-04-29	Elf Sanofi	Polycyclic amine compounds and their enantiomers, their method of preparation and pharmaceutical compositions on which they are present
EP0606222A1 (en) *	1991-08-08	1994-07-20	A. Menarini Industrie Farmaceutiche Riunite S.R.L.	Cyclic hexapeptides as tachyquinin antagonists, their preparation and pharmaceutical compositions thereof
US5731285A (en) *	1992-04-15	1998-03-24	A. Menatini Industrie Farmaceutiche	Tachiquinine antagonist tricyclic compounds, preparation of same and pharmaceutical compositions containing such compounds
PT2408802T (pt) *	2009-03-16	2017-08-03	Governing Council Univ Toronto	Moléculas de aminoácido ciclicas e métodos para as preparar
US11072616B2 (en)	2015-11-11	2021-07-27	Universite De Montreal	Cyclic peptides targeting alpha-4-beta-7 integrin
ES2884107T3 (es)	2016-11-11	2021-12-10	Zealand Pharma As	Multímeros de péptidos cíclicos con diana en la integrina alfa-4 beta-7
US11286281B2 (en)	2017-05-10	2022-03-29	Zealand Pharma A/S	Homodetic cyclic peptides targeting alpha-4-beta-7 integrin

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US4742156A (en) *	1985-09-30	1988-05-03	Mcneilab, Inc.	Peptide antagonists of neurokinin B and opthalmic solutions containing them
US4665157A (en) *	1985-09-30	1987-05-12	Mcneilab, Inc.	Peptide antagonists of neurokinin B
DE3711335A1 (de) *	1987-04-03	1988-10-20	Merck Patent Gmbh	Aminosaeurederivate
GB8807246D0 (en) *	1988-03-25	1988-04-27	Merck Sharp & Dohme	Therapeutic agents
ZA894533B (en) *	1988-06-20	1990-03-28	Merrell Dow Pharma	Neurokinin a antogonists
FI97540C (fi) *	1989-11-06	1997-01-10	Sanofi Sa	Menetelmä terapeuttisesti käyttökelpoisten, aromaattisesti substituoitujen piperidiini- ja piperatsiinijohdannaisten valmistamiseksi
IL99320A (en) *	1990-09-05	1995-07-31	Sanofi Sa	Arylalkylamines, their preparation and pharmaceutical compositions containing them
FR2677361A1 (fr) *	1991-06-04	1992-12-11	Adir	Nouveaux peptides et pseudopeptides, derives de tachykinines, leur procede de preparation et les compositions pharmaceutiques qui les contiennent.

1990
- 1990-08-06 ZA ZA906188A patent/ZA906188B/xx unknown
- 1990-08-06 AU AU60222/90A patent/AU638264B2/en not_active Expired
- 1990-08-07 CA CA002022740A patent/CA2022740C/en not_active Expired - Lifetime
- 1990-08-07 AR AR90317547A patent/AR246087A1/es active
- 1990-08-07 IL IL9530990A patent/IL95309A/en not_active IP Right Cessation
- 1990-08-08 NZ NZ234814A patent/NZ234814A/en unknown
- 1990-08-08 FI FI903922A patent/FI95913C/fi active IP Right Grant
- 1990-08-09 AT AT90115309T patent/ATE132503T1/de not_active IP Right Cessation
- 1990-08-09 CN CN90106972A patent/CN1035056C/zh not_active Expired - Fee Related
- 1990-08-09 PT PT94952A patent/PT94952B/pt not_active IP Right Cessation
- 1990-08-09 KR KR1019900012226A patent/KR0169123B1/ko not_active Expired - Fee Related
- 1990-08-09 DE DE69024555T patent/DE69024555T2/de not_active Expired - Lifetime
- 1990-08-09 ES ES90115309T patent/ES2084627T3/es not_active Expired - Lifetime
- 1990-08-09 EP EP90115309A patent/EP0412542B1/en not_active Expired - Lifetime
- 1990-08-09 JP JP2209390A patent/JP2829779B2/ja not_active Expired - Lifetime
- 1990-08-09 DK DK90115309.8T patent/DK0412542T3/da active
- 1990-08-09 IE IE288690A patent/IE69382B1/en not_active IP Right Cessation
- 1990-08-09 NO NO903513A patent/NO177715C/no unknown
- 1990-08-09 HU HU904952A patent/HU206729B/hu not_active IP Right Cessation
- 1990-08-10 DD DD90343398A patent/DD297168A5/de unknown
1996
- 1996-02-14 GR GR960400385T patent/GR3018984T3/el unknown
1997
- 1997-03-05 US US08/811,913 patent/US5731286A/en not_active Expired - Fee Related

Also Published As

Publication number	Publication date
GR3018984T3 (en)	1996-05-31
FI95913C (fi)	1996-04-10
ZA906188B (en)	1991-06-26
IL95309A0 (en)	1991-06-30
NO903513L (no)	1991-02-11
DK0412542T3 (da)	1996-01-29
DD297168A5 (de)	1992-01-02
PT94952B (pt)	1997-07-31
ES2084627T3 (es)	1996-05-16
ATE132503T1 (de)	1996-01-15
JPH03141295A (ja)	1991-06-17
CA2022740C (en)	2000-05-02
NO177715C (no)	1995-11-08
DE69024555D1 (de)	1996-02-15
NZ234814A (en)	1992-03-26
DE69024555T2 (de)	1996-05-15
CN1035056C (zh)	1997-06-04
FI95913B (fi)	1995-12-29
HUT54713A (en)	1991-03-28
NO177715B (no)	1995-07-31
IE902886A1 (en)	1991-02-27
US5731286A (en)	1998-03-24
IE69382B1 (en)	1996-09-04
KR0169123B1 (ko)	1999-01-15
EP0412542B1 (en)	1996-01-03
CA2022740A1 (en)	1991-02-11
IL95309A (en)	1995-07-31
JP2829779B2 (ja)	1998-12-02
KR910004665A (ko)	1991-03-29
HU206729B (en)	1992-12-28
EP0412542A2 (en)	1991-02-13
AR246087A1 (es)	1994-03-30
NO903513D0 (no)	1990-08-09
EP0412542A3 (en)	1991-07-24
AU6022290A (en)	1991-05-16
CN1049353A (zh)	1991-02-20
HU904952D0 (en)	1991-01-28
AU638264B2 (en)	1993-06-24
FI903922A0 (fi)	1990-08-08

Legal Events

Date

Code

Title

Description

1991-04-18

BB1A

Laying open of patent application

Effective date: 19901107

1997-07-31

FG3A

Patent granted, date of granting

Effective date: 19970502

2012-05-09

MM4A

Annulment/lapse due to non-payment of fees, searched and examined patent

Free format text: MAXIMUM VALIDITY LIMIT REACHED

Effective date: 20120502

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