PT94960A - Processo para a preparacao de derivados de quinolina e de composicoes farmaceuticas que as contem - Google Patents

Processo para a preparacao de derivados de quinolina e de composicoes farmaceuticas que as contem Download PDF

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Publication number
PT94960A
PT94960A PT94960A PT9496090A PT94960A PT 94960 A PT94960 A PT 94960A PT 94960 A PT94960 A PT 94960A PT 9496090 A PT9496090 A PT 9496090A PT 94960 A PT94960 A PT 94960A
Authority
PT
Portugal
Prior art keywords
hit hit
ethyl
methyl
formula
quinoline
Prior art date
Application number
PT94960A
Other languages
English (en)
Portuguese (pt)
Inventor
David Anthony Roberts
Simon Thomas Russell
Robert James Pearce
Original Assignee
Ici Plc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GB898918402A external-priority patent/GB8918402D0/en
Priority claimed from GB909003187A external-priority patent/GB9003187D0/en
Application filed by Ici Plc filed Critical Ici Plc
Publication of PT94960A publication Critical patent/PT94960A/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
    • C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D215/20—Oxygen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
    • C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D215/20—Oxygen atoms
    • C07D215/22—Oxygen atoms attached in position 2 or 4
    • C07D215/233—Oxygen atoms attached in position 2 or 4 only one oxygen atom which is attached in position 4
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Health & Medical Sciences (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Quinoline Compounds (AREA)
PT94960A 1989-08-11 1990-08-10 Processo para a preparacao de derivados de quinolina e de composicoes farmaceuticas que as contem PT94960A (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB898918402A GB8918402D0 (en) 1989-08-11 1989-08-11 Nitrogen compounds
GB909003187A GB9003187D0 (en) 1990-02-13 1990-02-13 Nitrogen compounds

Publications (1)

Publication Number Publication Date
PT94960A true PT94960A (pt) 1991-04-18

Family

ID=26295741

Family Applications (1)

Application Number Title Priority Date Filing Date
PT94960A PT94960A (pt) 1989-08-11 1990-08-10 Processo para a preparacao de derivados de quinolina e de composicoes farmaceuticas que as contem

Country Status (18)

Country Link
US (1) US5444071A (fr)
EP (1) EP0412848B1 (fr)
JP (1) JP3010056B2 (fr)
KR (1) KR910004571A (fr)
CN (1) CN1050187A (fr)
AP (1) AP161A (fr)
AT (1) ATE117294T1 (fr)
AU (1) AU623546B2 (fr)
BG (1) BG92674A (fr)
DE (1) DE69016125T2 (fr)
FI (1) FI903966A7 (fr)
HU (1) HUT54991A (fr)
IE (1) IE902909A1 (fr)
NO (1) NO903525L (fr)
NZ (1) NZ234854A (fr)
PL (1) PL286445A1 (fr)
PT (1) PT94960A (fr)
YU (1) YU155290A (fr)

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CN105764916B (zh) 2013-06-05 2021-05-18 博士医疗爱尔兰有限公司 鸟苷酸环化酶c的超纯激动剂、制备和使用所述激动剂的方法
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US20200407720A1 (en) 2018-03-13 2020-12-31 Onxeo A dbait molecule against acquired resistance in the treatment of cancer
WO2021148581A1 (fr) 2020-01-22 2021-07-29 Onxeo Nouvelle molécule dbait et son utilisation
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CN121398822A (zh) 2023-06-21 2026-01-23 四方生物科学有限公司 用于在治疗hr功能正常的癌症的方法中的用途的包含脱氧胞苷衍生物和parp抑制剂的组合

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Also Published As

Publication number Publication date
JPH03169863A (ja) 1991-07-23
HUT54991A (en) 1991-04-29
EP0412848A3 (en) 1991-04-10
JP3010056B2 (ja) 2000-02-14
CN1050187A (zh) 1991-03-27
AU6095590A (en) 1991-02-14
AU623546B2 (en) 1992-05-14
ATE117294T1 (de) 1995-02-15
DE69016125D1 (de) 1995-03-02
AP9000197A0 (en) 1990-10-31
EP0412848B1 (fr) 1995-01-18
NO903525L (no) 1991-02-12
KR910004571A (ko) 1991-03-28
FI903966A0 (fi) 1990-08-10
PL286445A1 (en) 1991-04-22
US5444071A (en) 1995-08-22
FI903966A7 (fi) 1991-02-12
NO903525D0 (no) 1990-08-10
EP0412848A2 (fr) 1991-02-13
NZ234854A (en) 1993-02-25
AP161A (en) 1991-12-20
YU155290A (sh) 1993-05-28
BG92674A (bg) 1993-12-24
HU904961D0 (en) 1991-01-28
DE69016125T2 (de) 1995-06-01
IE902909A1 (en) 1991-02-27

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BB1A Laying open of patent application

Effective date: 19901108

FC3A Refusal

Effective date: 19960719