PT96235A - Processo de preparacao de derivados da piperidina e de composicoes farmaceuticas que os contem - Google Patents
Processo de preparacao de derivados da piperidina e de composicoes farmaceuticas que os contemInfo
- Publication number
- PT96235A PT96235A PT96235A PT9623590A PT96235A PT 96235 A PT96235 A PT 96235A PT 96235 A PT96235 A PT 96235A PT 9623590 A PT9623590 A PT 9623590A PT 96235 A PT96235 A PT 96235A
- Authority
- PT
- Portugal
- Prior art keywords
- alkyl
- hydrogen
- pharmaceutical compositions
- preparation process
- compositions containing
- Prior art date
Links
- NQRYJNQNLNOLGT-UHFFFAOYSA-N Piperidine Chemical class C1CCNCC1 NQRYJNQNLNOLGT-UHFFFAOYSA-N 0.000 title 1
- 239000008194 pharmaceutical composition Substances 0.000 title 1
- 238000002360 preparation method Methods 0.000 title 1
- 125000004169 (C1-C6) alkyl group Chemical group 0.000 abstract 3
- -1 3,4-methylenedioxyphenyl Chemical group 0.000 abstract 3
- 229910052739 hydrogen Inorganic materials 0.000 abstract 3
- 239000001257 hydrogen Substances 0.000 abstract 3
- 125000004209 (C1-C8) alkyl group Chemical group 0.000 abstract 2
- 125000000882 C2-C6 alkenyl group Chemical group 0.000 abstract 2
- 150000002431 hydrogen Chemical group 0.000 abstract 2
- 229910052760 oxygen Inorganic materials 0.000 abstract 2
- 229910052717 sulfur Inorganic materials 0.000 abstract 2
- 125000004178 (C1-C4) alkyl group Chemical group 0.000 abstract 1
- 125000004191 (C1-C6) alkoxy group Chemical group 0.000 abstract 1
- 125000006552 (C3-C8) cycloalkyl group Chemical group 0.000 abstract 1
- 206010002660 Anoxia Diseases 0.000 abstract 1
- 241000976983 Anoxia Species 0.000 abstract 1
- 125000003601 C2-C6 alkynyl group Chemical group 0.000 abstract 1
- 206010021143 Hypoxia Diseases 0.000 abstract 1
- 208000019695 Migraine disease Diseases 0.000 abstract 1
- 239000002253 acid Substances 0.000 abstract 1
- 125000003277 amino group Chemical group 0.000 abstract 1
- 230000007953 anoxia Effects 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 125000004093 cyano group Chemical group *C#N 0.000 abstract 1
- 206010015037 epilepsy Diseases 0.000 abstract 1
- 229910052736 halogen Inorganic materials 0.000 abstract 1
- 150000002367 halogens Chemical class 0.000 abstract 1
- 125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 1
- 208000014674 injury Diseases 0.000 abstract 1
- 208000028867 ischemia Diseases 0.000 abstract 1
- 206010027599 migraine Diseases 0.000 abstract 1
- 125000001624 naphthyl group Chemical group 0.000 abstract 1
- 125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 abstract 1
- 150000003053 piperidines Chemical class 0.000 abstract 1
- 125000002924 primary amino group Chemical group [H]N([H])* 0.000 abstract 1
- 150000003839 salts Chemical group 0.000 abstract 1
- 230000008736 traumatic injury Effects 0.000 abstract 1
- 125000000876 trifluoromethoxy group Chemical group FC(F)(F)O* 0.000 abstract 1
- 125000002023 trifluoromethyl group Chemical group FC(F)(F)* 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/06—Antimigraine agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/04—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/14—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
- C07D409/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing three or more hetero rings
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Neurosurgery (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Pain & Pain Management (AREA)
- Obesity (AREA)
- Hematology (AREA)
- Diabetes (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Hydrogenated Pyridines (AREA)
- Plural Heterocyclic Compounds (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Saccharide Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DK640289A DK640289D0 (da) | 1989-12-18 | 1989-12-18 | Ny heterocyklisk kemi |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| PT96235A true PT96235A (pt) | 1991-09-30 |
| PT96235B PT96235B (pt) | 1998-06-30 |
Family
ID=8148694
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PT96235A PT96235B (pt) | 1989-12-18 | 1990-12-18 | Processo de preparacao de derivados da piperidina e de composicoes farmaceuticas que os contem |
Country Status (18)
| Country | Link |
|---|---|
| US (1) | US5102894A (pt) |
| EP (1) | EP0505465B1 (pt) |
| JP (1) | JPH05502867A (pt) |
| CN (1) | CN1052674A (pt) |
| AT (1) | ATE135704T1 (pt) |
| AU (1) | AU645722B2 (pt) |
| CA (1) | CA2071480A1 (pt) |
| DE (1) | DE69026110T2 (pt) |
| DK (2) | DK640289D0 (pt) |
| ES (1) | ES2084151T3 (pt) |
| FI (1) | FI922826A7 (pt) |
| IE (1) | IE904435A1 (pt) |
| IL (2) | IL96592A (pt) |
| NO (2) | NO922313L (pt) |
| PT (1) | PT96235B (pt) |
| WO (1) | WO1991009032A1 (pt) |
| ZA (1) | ZA9010183B (pt) |
| ZW (1) | ZW19190A1 (pt) |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2763589B1 (fr) | 1997-05-22 | 2001-01-05 | Centre Nat Rech Scient | Composes pour la preparation de medicaments destines au traitement de pathologies impliquant le glutamate extracellulaire, et leurs procedes d'obtention |
| US7294637B2 (en) | 2000-09-11 | 2007-11-13 | Sepracor, Inc. | Method of treating addiction or dependence using a ligand for a monamine receptor or transporter |
| EP1318988A2 (en) | 2000-09-11 | 2003-06-18 | Sepracor, Inc. | Ligands for monoamine receptors and transporters, and methods of use thereof (neurotransmission) |
| US7531555B2 (en) | 2003-10-01 | 2009-05-12 | University Of Florida Research Foundation, Inc. | Compositions and methods for selective inhibition of nicotine acetylcholine receptors |
| KR20080013853A (ko) * | 2005-02-23 | 2008-02-13 | 사이케노믹스, 인코퍼레이티드 | 복수매개물질 도파민 수송체 저해물질 및 이와 관련된 용도 |
| US8258305B2 (en) | 2005-02-23 | 2012-09-04 | Prexa Pharmaceuticals, Inc. | Dopamine transporter inhibitors for use in treatment of movement disorders and other CNS indications |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US2895965A (en) * | 1959-07-21 | Process for the production of | ||
| GB1422263A (en) * | 1973-01-30 | 1976-01-21 | Ferrosan As | 4-phenyl-piperidine compounds |
| IE66332B1 (en) * | 1986-11-03 | 1995-12-27 | Novo Nordisk As | Piperidine compounds and their preparation and use |
| US5017585A (en) * | 1986-11-03 | 1991-05-21 | Novo Nordisk A/S | Method of treating calcium overload |
| DK231088D0 (da) * | 1988-04-28 | 1988-04-28 | Ferrosan As | Piperidinforbindelser, deres fremstilling og anvendelse |
| DK588289D0 (da) * | 1989-11-22 | 1989-11-22 | Ferrosan As | Ny heterocyklisk kemi |
-
1989
- 1989-12-18 DK DK640289A patent/DK640289D0/da not_active Application Discontinuation
-
1990
- 1990-12-03 US US07/623,868 patent/US5102894A/en not_active Expired - Fee Related
- 1990-12-06 ZW ZW191/90A patent/ZW19190A1/xx unknown
- 1990-12-07 IL IL9695290A patent/IL96592A/en not_active IP Right Cessation
- 1990-12-07 IL IL96592A patent/IL96592A0/xx unknown
- 1990-12-10 IE IE443590A patent/IE904435A1/en unknown
- 1990-12-11 EP EP91901483A patent/EP0505465B1/en not_active Expired - Lifetime
- 1990-12-11 AU AU69716/91A patent/AU645722B2/en not_active Ceased
- 1990-12-11 WO PCT/DK1990/000325 patent/WO1991009032A1/en not_active Ceased
- 1990-12-11 ES ES91901483T patent/ES2084151T3/es not_active Expired - Lifetime
- 1990-12-11 CA CA002071480A patent/CA2071480A1/en not_active Abandoned
- 1990-12-11 JP JP3501812A patent/JPH05502867A/ja active Pending
- 1990-12-11 FI FI922826A patent/FI922826A7/fi not_active Application Discontinuation
- 1990-12-11 DK DK91901483.7T patent/DK0505465T3/da active
- 1990-12-11 DE DE69026110T patent/DE69026110T2/de not_active Expired - Fee Related
- 1990-12-11 AT AT91901483T patent/ATE135704T1/de not_active IP Right Cessation
- 1990-12-18 PT PT96235A patent/PT96235B/pt not_active IP Right Cessation
- 1990-12-18 ZA ZA9010183A patent/ZA9010183B/xx unknown
- 1990-12-18 CN CN90110145A patent/CN1052674A/zh active Pending
-
1992
- 1992-06-12 NO NO92922313A patent/NO922313L/no unknown
-
1994
- 1994-07-01 NO NO1994003C patent/NO1994003I1/no unknown
Also Published As
| Publication number | Publication date |
|---|---|
| DK640289D0 (da) | 1989-12-18 |
| NO922313D0 (no) | 1992-06-12 |
| ATE135704T1 (de) | 1996-04-15 |
| CN1052674A (zh) | 1991-07-03 |
| US5102894A (en) | 1992-04-07 |
| EP0505465A1 (en) | 1992-09-30 |
| NO922313L (no) | 1992-06-12 |
| IL96592A0 (en) | 1991-09-16 |
| WO1991009032A1 (en) | 1991-06-27 |
| FI922826A0 (fi) | 1992-06-17 |
| IE904435A1 (en) | 1991-06-19 |
| DE69026110D1 (de) | 1996-04-25 |
| FI922826L (fi) | 1992-06-17 |
| PT96235B (pt) | 1998-06-30 |
| DE69026110T2 (de) | 1996-10-02 |
| ZA9010183B (en) | 1991-10-30 |
| CA2071480A1 (en) | 1991-06-19 |
| FI922826A7 (fi) | 1992-06-17 |
| NO1994003I1 (no) | 1994-07-01 |
| ZW19190A1 (en) | 1991-06-05 |
| JPH05502867A (ja) | 1993-05-20 |
| IL96592A (en) | 1995-06-29 |
| AU6971691A (en) | 1991-07-18 |
| AU645722B2 (en) | 1994-01-20 |
| DK0505465T3 (da) | 1996-08-05 |
| EP0505465B1 (en) | 1996-03-20 |
| ES2084151T3 (es) | 1996-05-01 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| BB1A | Laying open of patent application |
Effective date: 19910430 |
|
| FG3A | Patent granted, date of granting |
Effective date: 19980313 |
|
| MM3A | Annulment or lapse |
Free format text: LAPSE DUE TO NON-PAYMENT OF FEES Effective date: 19990930 |