PT97571A - Processo para a prparacao de hidrazonas - Google Patents

Processo para a prparacao de hidrazonas

Info

Publication number
PT97571A
PT97571A PT97571A PT9757191A PT97571A PT 97571 A PT97571 A PT 97571A PT 97571 A PT97571 A PT 97571A PT 9757191 A PT9757191 A PT 9757191A PT 97571 A PT97571 A PT 97571A
Authority
PT
Portugal
Prior art keywords
independently
hydrogen
another
lower alkyl
hydroxyl
Prior art date
Application number
PT97571A
Other languages
English (en)
Other versions
PT97571B (pt
Inventor
Jaroslav Stanek
Jorg Frei
Giorgio Caravatti
Original Assignee
Ciba Geigy Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ciba Geigy Ag filed Critical Ciba Geigy Ag
Publication of PT97571A publication Critical patent/PT97571A/pt
Publication of PT97571B publication Critical patent/PT97571B/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C337/00—Derivatives of thiocarbonic acids containing functional groups covered by groups C07C333/00 or C07C335/00 in which at least one nitrogen atom of these functional groups is further bound to another nitrogen atom not being part of a nitro or nitroso group
    • C07C337/06—Compounds containing any of the groups, e.g. thiosemicarbazides
    • C07C337/08—Compounds containing any of the groups, e.g. thiosemicarbazides the other nitrogen atom being further doubly-bound to a carbon atom, e.g. thiosemicarbazones
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • A61P33/02—Antiprotozoals, e.g. for leishmaniasis, trichomoniasis, toxoplasmosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • A61P33/02—Antiprotozoals, e.g. for leishmaniasis, trichomoniasis, toxoplasmosis
    • A61P33/06—Antimalarials
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C243/00—Compounds containing chains of nitrogen atoms singly-bound to each other, e.g. hydrazines, triazanes
    • C07C243/10—Hydrazines
    • C07C243/20—Hydrazines having nitrogen atoms of hydrazine groups bound to carbon atoms of rings other than six-membered aromatic rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C281/00—Derivatives of carbonic acid containing functional groups covered by groups C07C269/00 - C07C279/00 in which at least one nitrogen atom of these functional groups is further bound to another nitrogen atom not being part of a nitro or nitroso group
    • C07C281/06—Compounds containing any of the groups, e.g. semicarbazides
    • C07C281/08—Compounds containing any of the groups, e.g. semicarbazides the other nitrogen atom being further doubly-bound to a carbon atom, e.g. semicarbazones
    • C07C281/12—Compounds containing any of the groups, e.g. semicarbazides the other nitrogen atom being further doubly-bound to a carbon atom, e.g. semicarbazones the carbon atom being part of a ring other than a six-membered aromatic ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C281/00—Derivatives of carbonic acid containing functional groups covered by groups C07C269/00 - C07C279/00 in which at least one nitrogen atom of these functional groups is further bound to another nitrogen atom not being part of a nitro or nitroso group
    • C07C281/16—Compounds containing any of the groups, e.g. aminoguanidine
    • C07C281/18—Compounds containing any of the groups, e.g. aminoguanidine the other nitrogen atom being further doubly-bound to a carbon atom, e.g. guanylhydrazones
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2602/00—Systems containing two condensed rings
    • C07C2602/02—Systems containing two condensed rings the rings having only two atoms in common
    • C07C2602/04—One of the condensed rings being a six-membered aromatic ring
    • C07C2602/06—One of the condensed rings being a six-membered aromatic ring the other ring being four-membered
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2602/00—Systems containing two condensed rings
    • C07C2602/02—Systems containing two condensed rings the rings having only two atoms in common
    • C07C2602/04—One of the condensed rings being a six-membered aromatic ring
    • C07C2602/08—One of the condensed rings being a six-membered aromatic ring the other ring being five-membered, e.g. indane

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Materials For Photolithography (AREA)
  • Peptides Or Proteins (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Diaphragms For Electromechanical Transducers (AREA)
  • Ultra Sonic Daignosis Equipment (AREA)
  • Wire Bonding (AREA)
PT97571A 1990-05-07 1991-05-06 Processo para a prparacao de hidrazonas PT97571B (pt)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CH153890 1990-05-07

Publications (2)

Publication Number Publication Date
PT97571A true PT97571A (pt) 1992-01-31
PT97571B PT97571B (pt) 1999-04-30

Family

ID=4212764

Family Applications (1)

Application Number Title Priority Date Filing Date
PT97571A PT97571B (pt) 1990-05-07 1991-05-06 Processo para a prparacao de hidrazonas

Country Status (26)

Country Link
EP (1) EP0456133B1 (pt)
JP (1) JP2565602B2 (pt)
KR (1) KR100203234B1 (pt)
AT (1) ATE119878T1 (pt)
AU (1) AU645799B2 (pt)
CA (1) CA2041832C (pt)
CY (1) CY2080B1 (pt)
CZ (1) CZ279340B6 (pt)
DE (1) DE59104930D1 (pt)
DK (1) DK0456133T3 (pt)
ES (1) ES2069768T3 (pt)
FI (1) FI107916B (pt)
GR (1) GR3015574T3 (pt)
HK (1) HK1000919A1 (pt)
HU (1) HU218221B (pt)
ID (1) ID1040B (pt)
IE (1) IE66157B1 (pt)
IL (1) IL98008A (pt)
NO (1) NO175097C (pt)
NZ (1) NZ238033A (pt)
PT (1) PT97571B (pt)
RU (2) RU2057748C1 (pt)
SA (1) SA91120283B1 (pt)
SK (1) SK279136B6 (pt)
TW (1) TW202428B (pt)
ZA (1) ZA913391B (pt)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5395855A (en) * 1990-05-07 1995-03-07 Ciba-Geigy Corporation Hydrazones
RU2081108C1 (ru) * 1991-10-16 1997-06-10 Циба-Гейги АГ Аддитивные соли кислот с основанием и фармацевтическая композиция, обладающая противоопухолевой активностью
JPH06508375A (ja) * 1992-04-03 1994-09-22 イノテラ インダン−１，３−ジオンおよびインダン−１，２，３−トリオンの誘導体、それらの調製方法およびそれらの治療上の使用
ES2103166B1 (es) * 1992-08-26 1998-04-01 Ciba Geigy Ag Procedimiento para la obtencion de amidinohidrazonas biciclicas.
FR2710639B1 (fr) * 1993-10-01 1995-12-22 Innothera Lab Sa Dérivés d'indane cétoniques, leur procédé d'obtention, leur application thérapeutique.
ATE278676T1 (de) * 1995-01-26 2004-10-15 Novartis Pharma Gmbh Imdazol-derivate, deren herstellung und deren verwendung als s-adenosylmethionin decarboxylase (=samdc) inhibitoren
EP1408028A1 (en) * 2002-10-09 2004-04-14 Institut National De La Sante Et De La Recherche Medicale (Inserm) S-adenosyl methionine decarboxylase inhibition for the treatment of a herpes simplex virus infection
EP1834669A1 (en) * 2006-03-15 2007-09-19 Heinrich-Pette-Institut Use of specific hydrazone compounds for the treatment of viral infections
EP1884515A1 (en) * 2006-07-31 2008-02-06 Laboratorios del Dr. Esteve S.A. Substituted indanyl sulfonamide compounds, their preparation and use as medicaments
CN102627593A (zh) * 2012-02-23 2012-08-08 河南师范大学 具有抗癌活性的1，4-二羟基-2-甲酰基-9，10蒽醌缩氨硫脲新化合物及制备方法
KR20170027737A (ko) * 2014-07-02 2017-03-10 인플렉티스 바이오사이언스 O-알킬-벤질리덴구아니딘 유도체 및 미스폴딩된 단백질의 축적 관련 장애의 치료를 위한 치료 용도

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NL7407469A (nl) * 1974-06-01 1975-12-03 Akzo Nv Nieuwe amidinohydrazonverbindingen.
DE3416695A1 (de) * 1984-05-05 1985-11-07 Bayer Ag, 5090 Leverkusen Amidinohydrazone von tetralin-, chromon-, thiochromon- und tretrahydrochinolin-derivaten, verfahren zu ihrer herstellung sowie ihre verwendung in arzneimitteln
EP0377304B1 (en) * 1988-12-27 1994-03-09 E.I. Du Pont De Nemours And Company Substituted semicarbazone arthropodicides

Also Published As

Publication number Publication date
EP0456133B1 (de) 1995-03-15
SK279136B6 (sk) 1998-07-08
TW202428B (pt) 1993-03-21
CY2080B1 (en) 1998-10-16
ZA913391B (en) 1991-12-24
IL98008A (en) 1996-08-04
RU2057748C1 (ru) 1996-04-10
HUT57183A (en) 1991-11-28
CA2041832C (en) 2002-09-17
KR910019964A (ko) 1991-12-19
CA2041832A1 (en) 1991-11-08
ES2069768T3 (es) 1995-05-16
AU645799B2 (en) 1994-01-27
CZ279340B6 (cs) 1995-04-12
ID1040B (id) 1996-10-25
NZ238033A (en) 1993-01-27
ATE119878T1 (de) 1995-04-15
NO911777D0 (no) 1991-05-06
IE66157B1 (en) 1995-12-13
IL98008A0 (en) 1992-06-21
FI107916B (fi) 2001-10-31
SA91120283B1 (ar) 2005-12-17
HK1000919A1 (en) 1998-05-08
IE911530A1 (en) 1991-11-20
CS131791A3 (en) 1992-03-18
DE59104930D1 (de) 1995-04-20
EP0456133A1 (de) 1991-11-13
JPH04225946A (ja) 1992-08-14
AU7596791A (en) 1991-11-07
RU2066311C1 (ru) 1996-09-10
DK0456133T3 (da) 1995-05-22
NO175097C (no) 1994-08-31
HU218221B (hu) 2000-06-28
PT97571B (pt) 1999-04-30
NO911777L (no) 1991-11-08
FI912164L (fi) 1991-11-08
JP2565602B2 (ja) 1996-12-18
GR3015574T3 (en) 1995-06-30
FI912164A0 (fi) 1991-05-03
KR100203234B1 (ko) 1999-06-15
NO175097B (no) 1994-05-24

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Legal Events

Date Code Title Description
BB1A Laying open of patent application

Effective date: 19911004

FG3A Patent granted, date of granting

Effective date: 19990111

MM4A Annulment/lapse due to non-payment of fees, searched and examined patent

Free format text: LAPSE DUE TO NON-PAYMENT OF FEES

Effective date: 20110711