PT97571A - Processo para a prparacao de hidrazonas - Google Patents

Processo para a prparacao de hidrazonas

Info

Publication number: PT97571A
Authority: PT; Portugal
Prior art keywords: independently; hydrogen; another; lower alkyl; hydroxyl
Prior art date: 1990-05-07

Application number

PT97571A

Other languages

English (en)

Other versions

PT97571B (pt

Inventor

Jaroslav Stanek

Jorg Frei

Giorgio Caravatti

Original Assignee

Ciba Geigy Ag

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1990-05-07

Filing date

1991-05-06

Publication date

1992-01-31

1991-05-06 Application filed by Ciba Geigy Ag filed Critical Ciba Geigy Ag

1992-01-31 Publication of PT97571A publication Critical patent/PT97571A/pt

1999-04-30 Publication of PT97571B publication Critical patent/PT97571B/pt

Links

150000007857 hydrazones Chemical class 0.000 title 1
229910052739 hydrogen Inorganic materials 0.000 abstract 4
239000001257 hydrogen Substances 0.000 abstract 4
UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 abstract 3
125000000217 alkyl group Chemical group 0.000 abstract 2
125000002887 hydroxy group Chemical group [H]O* 0.000 abstract 2
206010028980 Neoplasm Diseases 0.000 abstract 1
150000001875 compounds Chemical class 0.000 abstract 1
150000002431 hydrogen Chemical group 0.000 abstract 1
125000002924 primary amino group Chemical group [H]N([H])* 0.000 abstract 1
150000003839 salts Chemical class 0.000 abstract 1
125000001424 substituent group Chemical group 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C337/00—Derivatives of thiocarbonic acids containing functional groups covered by groups C07C333/00 or C07C335/00 in which at least one nitrogen atom of these functional groups is further bound to another nitrogen atom not being part of a nitro or nitroso group
- C07C337/06—Compounds containing any of the groups, e.g. thiosemicarbazides
- C07C337/08—Compounds containing any of the groups, e.g. thiosemicarbazides the other nitrogen atom being further doubly-bound to a carbon atom, e.g. thiosemicarbazones
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P33/00—Antiparasitic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P33/00—Antiparasitic agents
- A61P33/02—Antiprotozoals, e.g. for leishmaniasis, trichomoniasis, toxoplasmosis
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P33/00—Antiparasitic agents
- A61P33/02—Antiprotozoals, e.g. for leishmaniasis, trichomoniasis, toxoplasmosis
- A61P33/06—Antimalarials
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C243/00—Compounds containing chains of nitrogen atoms singly-bound to each other, e.g. hydrazines, triazanes
- C07C243/10—Hydrazines
- C07C243/20—Hydrazines having nitrogen atoms of hydrazine groups bound to carbon atoms of rings other than six-membered aromatic rings
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C281/00—Derivatives of carbonic acid containing functional groups covered by groups C07C269/00 - C07C279/00 in which at least one nitrogen atom of these functional groups is further bound to another nitrogen atom not being part of a nitro or nitroso group
- C07C281/06—Compounds containing any of the groups, e.g. semicarbazides
- C07C281/08—Compounds containing any of the groups, e.g. semicarbazides the other nitrogen atom being further doubly-bound to a carbon atom, e.g. semicarbazones
- C07C281/12—Compounds containing any of the groups, e.g. semicarbazides the other nitrogen atom being further doubly-bound to a carbon atom, e.g. semicarbazones the carbon atom being part of a ring other than a six-membered aromatic ring
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C281/00—Derivatives of carbonic acid containing functional groups covered by groups C07C269/00 - C07C279/00 in which at least one nitrogen atom of these functional groups is further bound to another nitrogen atom not being part of a nitro or nitroso group
- C07C281/16—Compounds containing any of the groups, e.g. aminoguanidine
- C07C281/18—Compounds containing any of the groups, e.g. aminoguanidine the other nitrogen atom being further doubly-bound to a carbon atom, e.g. guanylhydrazones
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C2602/00—Systems containing two condensed rings
- C07C2602/02—Systems containing two condensed rings the rings having only two atoms in common
- C07C2602/04—One of the condensed rings being a six-membered aromatic ring
- C07C2602/06—One of the condensed rings being a six-membered aromatic ring the other ring being four-membered
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C2602/00—Systems containing two condensed rings
- C07C2602/02—Systems containing two condensed rings the rings having only two atoms in common
- C07C2602/04—One of the condensed rings being a six-membered aromatic ring
- C07C2602/08—One of the condensed rings being a six-membered aromatic ring the other ring being five-membered, e.g. indane

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
Veterinary Medicine (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Medicinal Chemistry (AREA)
General Chemical & Material Sciences (AREA)
Pharmacology & Pharmacy (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Chemical Kinetics & Catalysis (AREA)
Tropical Medicine & Parasitology (AREA)
Bioinformatics & Cheminformatics (AREA)
Engineering & Computer Science (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Materials For Photolithography (AREA)
Plural Heterocyclic Compounds (AREA)
Peptides Or Proteins (AREA)
Wire Bonding (AREA)
Diaphragms For Electromechanical Transducers (AREA)
Ultra Sonic Daignosis Equipment (AREA)

PT97571A 1990-05-07 1991-05-06 Processo para a prparacao de hidrazonas PT97571B (pt)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
CH153890		1990-05-07

Publications (2)

Publication Number	Publication Date
PT97571A true PT97571A (pt)	1992-01-31
PT97571B PT97571B (pt)	1999-04-30

Family

ID=4212764

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
PT97571A PT97571B (pt)	1990-05-07	1991-05-06	Processo para a prparacao de hidrazonas

Country Status (25)

Country	Link
EP (1)	EP0456133B1 (pt)
JP (1)	JP2565602B2 (pt)
KR (1)	KR100203234B1 (pt)
AT (1)	ATE119878T1 (pt)
AU (1)	AU645799B2 (pt)
CA (1)	CA2041832C (pt)
CY (1)	CY2080B1 (pt)
CZ (1)	CZ279340B6 (pt)
DE (1)	DE59104930D1 (pt)
DK (1)	DK0456133T3 (pt)
ES (1)	ES2069768T3 (pt)
FI (1)	FI107916B (pt)
GR (1)	GR3015574T3 (pt)
HU (1)	HU218221B (pt)
ID (1)	ID1040B (pt)
IE (1)	IE66157B1 (pt)
IL (1)	IL98008A (pt)
NO (1)	NO175097C (pt)
NZ (1)	NZ238033A (pt)
PT (1)	PT97571B (pt)
RU (2)	RU2057748C1 (pt)
SA (1)	SA91120283B1 (pt)
SK (1)	SK279136B6 (pt)
TW (1)	TW202428B (pt)
ZA (1)	ZA913391B (pt)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US5395855A (en) *	1990-05-07	1995-03-07	Ciba-Geigy Corporation	Hydrazones
RU2081108C1 (ru) *	1991-10-16	1997-06-10	Циба-Гейги АГ	Аддитивные соли кислот с основанием и фармацевтическая композиция, обладающая противоопухолевой активностью
WO1993020045A1 (fr) *	1992-04-03	1993-10-14	Innothera	Derives d'indane-1,3-dione et d'indane-1,2,3-trione, leurs procedes de preparation et leur application en therapeutique
ES2103166B1 (es) *	1992-08-26	1998-04-01	Ciba Geigy Ag	Procedimiento para la obtencion de amidinohidrazonas biciclicas.
FR2710639B1 (fr) *	1993-10-01	1995-12-22	Innothera Lab Sa	Dérivés d'indane cétoniques, leur procédé d'obtention, leur application thérapeutique.
CA2210533C (en) *	1995-01-26	2007-12-04	Novartis Ag	Imidazole derivatives, their preparation and their use as s-adenosylmethionine decarboxylase (=samdc) inhibitors
EP1408028A1 (en) *	2002-10-09	2004-04-14	Institut National De La Sante Et De La Recherche Medicale (Inserm)	S-adenosyl methionine decarboxylase inhibition for the treatment of a herpes simplex virus infection
EP1834669A1 (en) *	2006-03-15	2007-09-19	Heinrich-Pette-Institut	Use of specific hydrazone compounds for the treatment of viral infections
EP1884515A1 (en) *	2006-07-31	2008-02-06	Laboratorios del Dr. Esteve S.A.	Substituted indanyl sulfonamide compounds, their preparation and use as medicaments
CN102627593A (zh) *	2012-02-23	2012-08-08	河南师范大学	具有抗癌活性的1，4-二羟基-2-甲酰基-9，10蒽醌缩氨硫脲新化合物及制备方法
KR20170027737A (ko) *	2014-07-02	2017-03-10	인플렉티스 바이오사이언스	O-알킬-벤질리덴구아니딘 유도체 및 미스폴딩된 단백질의 축적 관련 장애의 치료를 위한 치료 용도

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
NL7407469A (nl) *	1974-06-01	1975-12-03	Akzo Nv	Nieuwe amidinohydrazonverbindingen.
DE3416695A1 (de) *	1984-05-05	1985-11-07	Bayer Ag, 5090 Leverkusen	Amidinohydrazone von tetralin-, chromon-, thiochromon- und tretrahydrochinolin-derivaten, verfahren zu ihrer herstellung sowie ihre verwendung in arzneimitteln
EP0377304B1 (en) *	1988-12-27	1994-03-09	E.I. Du Pont De Nemours And Company	Substituted semicarbazone arthropodicides

1991
- 1991-04-26 AU AU75967/91A patent/AU645799B2/en not_active Ceased
- 1991-04-30 IL IL9800891A patent/IL98008A/en not_active IP Right Cessation
- 1991-05-02 TW TW080103460A patent/TW202428B/zh not_active IP Right Cessation
- 1991-05-03 EP EP91107225A patent/EP0456133B1/de not_active Expired - Lifetime
- 1991-05-03 AT AT91107225T patent/ATE119878T1/de not_active IP Right Cessation
- 1991-05-03 DK DK91107225.4T patent/DK0456133T3/da not_active Application Discontinuation
- 1991-05-03 CA CA002041832A patent/CA2041832C/en not_active Expired - Lifetime
- 1991-05-03 NZ NZ238033A patent/NZ238033A/xx unknown
- 1991-05-03 ES ES91107225T patent/ES2069768T3/es not_active Expired - Lifetime
- 1991-05-03 DE DE59104930T patent/DE59104930D1/de not_active Expired - Fee Related
- 1991-05-03 FI FI912164A patent/FI107916B/fi active
- 1991-05-06 PT PT97571A patent/PT97571B/pt not_active IP Right Cessation
- 1991-05-06 ZA ZA913391A patent/ZA913391B/xx unknown
- 1991-05-06 HU HU519/91A patent/HU218221B/hu not_active IP Right Cessation
- 1991-05-06 RU SU914895338A patent/RU2057748C1/ru active
- 1991-05-06 CZ CS911317A patent/CZ279340B6/cs not_active IP Right Cessation
- 1991-05-06 IE IE153091A patent/IE66157B1/en not_active IP Right Cessation
- 1991-05-06 KR KR1019910007285A patent/KR100203234B1/ko not_active Expired - Fee Related
- 1991-05-06 NO NO911777A patent/NO175097C/no not_active IP Right Cessation
- 1991-05-06 SK SK1317-91A patent/SK279136B6/sk not_active IP Right Cessation
- 1991-05-07 JP JP3101512A patent/JP2565602B2/ja not_active Expired - Fee Related
- 1991-12-17 SA SA91120283A patent/SA91120283B1/ar unknown
1992
- 1992-01-30 ID IDP189692A patent/ID1040B/id unknown
- 1992-10-23 RU RU9292004359A patent/RU2066311C1/ru active
1995
- 1995-03-30 GR GR950400746T patent/GR3015574T3/el unknown
1998
- 1998-10-16 CY CY9802080A patent/CY2080B1/xx unknown

Also Published As

Publication number	Publication date
CY2080B1 (en)	1998-10-16
KR910019964A (ko)	1991-12-19
HU218221B (hu)	2000-06-28
HK1000919A1 (en)	1998-05-08
RU2057748C1 (ru)	1996-04-10
JPH04225946A (ja)	1992-08-14
EP0456133B1 (de)	1995-03-15
IL98008A (en)	1996-08-04
ID1040B (id)	1996-10-25
FI912164A0 (fi)	1991-05-03
NO911777L (no)	1991-11-08
CA2041832C (en)	2002-09-17
SK279136B6 (sk)	1998-07-08
NO175097C (no)	1994-08-31
CA2041832A1 (en)	1991-11-08
ATE119878T1 (de)	1995-04-15
NO175097B (no)	1994-05-24
GR3015574T3 (en)	1995-06-30
NZ238033A (en)	1993-01-27
EP0456133A1 (de)	1991-11-13
DE59104930D1 (de)	1995-04-20
IE911530A1 (en)	1991-11-20
NO911777D0 (no)	1991-05-06
AU645799B2 (en)	1994-01-27
ES2069768T3 (es)	1995-05-16
IE66157B1 (en)	1995-12-13
FI107916B (fi)	2001-10-31
DK0456133T3 (da)	1995-05-22
FI912164L (fi)	1991-11-08
KR100203234B1 (ko)	1999-06-15
JP2565602B2 (ja)	1996-12-18
HUT57183A (en)	1991-11-28
SA91120283B1 (ar)	2005-12-17
IL98008A0 (en)	1992-06-21
ZA913391B (en)	1991-12-24
PT97571B (pt)	1999-04-30
RU2066311C1 (ru)	1996-09-10
AU7596791A (en)	1991-11-07
TW202428B (pt)	1993-03-21
CS131791A3 (en)	1992-03-18
CZ279340B6 (cs)	1995-04-12

Legal Events

Date

Code

Title

Description

1992-01-31

BB1A

Laying open of patent application

Effective date: 19911004

1999-04-30

FG3A

Patent granted, date of granting

Effective date: 19990111

2011-07-18

MM4A

Annulment/lapse due to non-payment of fees, searched and examined patent

Free format text: LAPSE DUE TO NON-PAYMENT OF FEES

Effective date: 20110711

Publication	Publication Date	Title
PT95584A (pt)	1991-09-13	Processo de preparacao de antraquinonas, dos seus intermediarios e de composicoes farmaceuticas
PT97571A (pt)	1992-01-31	Processo para a prparacao de hidrazonas
MA22540A1 (fr)	1992-12-31	Diaminophtalimides substitues et derives analogues .
MX9706394A (es)	1997-11-29	Compuestos de 1-aril-2-acilamino-etano y su uso como antagonistas de neuroquinina, especialmente neuroquinina-1.
ATE232386T1 (de)	2003-02-15	Neue endiyn-chinonimine und verfahren zu deren herstellung und verwendung
DK0490816T3 (da)	1997-09-22	Fluorforbindelser som aromatase-inhibitorer.
RU94002329A (ru)	1995-09-10	Модифицированные олигодезоксирибонуклеотиды, композиция, способ лечения и промежуточные соединения
DK640687D0 (da)	1987-12-07	Allylmercaptoacetylsydnoniminer, deres fremstilling og anvendelse
ID16479A (id)	1997-10-02	Senyawa-senyawa pengobatan
ATE247955T1 (de)	2003-09-15	Selenophen-antitumormittel
ATE278676T1 (de)	2004-10-15	Imdazol-derivate, deren herstellung und deren verwendung als s-adenosylmethionin decarboxylase (=samdc) inhibitoren
ATE545681T1 (de)	2012-03-15	Anthrachinonfarbstoffe
ES8206537A1 (es)	1982-08-16	Procedimiento para la obtencion de nuevos derivados de la tiazolo (3,2-a) pirimidina
GR3024388T3 (en)	1997-11-28	2-phenyl-and 2-thienyl-(2)-piperidine derivatives having neuroprotective properties
IE850128L (en)	1985-07-24	Guanidine derivatives
DK460789A (da)	1989-11-20	2-aminoacetamidderivater
GR3020323T3 (en)	1996-09-30	P-di(2-chloroethyl)amino)phenylalanine derivatives process for their preparation and pharmaceutical compositions containing them.