RU2275373C2 - Макрогетероциклические соединения - Google Patents

Макрогетероциклические соединения Download PDF

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Publication number
RU2275373C2
RU2275373C2 RU2003120442/04A RU2003120442A RU2275373C2 RU 2275373 C2 RU2275373 C2 RU 2275373C2 RU 2003120442/04 A RU2003120442/04 A RU 2003120442/04A RU 2003120442 A RU2003120442 A RU 2003120442A RU 2275373 C2 RU2275373 C2 RU 2275373C2
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Russia
Prior art keywords
compound
alkyl
mmol
reaction mixture
kinase
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RU2003120442/04A
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Russian (ru)
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RU2003120442A (ru
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Гее-Хонг КУО (US)
Гее-Хонг КУО
Кэтрин ПРОУТИ (US)
Кэтрин ПРОУТИ
АНДЖЕЛИС Алан ДЕ (US)
АНДЖЕЛИС Алан ДЕ
Хан-Ченг ЗАНГ (US)
Хан-Ченг ЗАНГ
Петер КОННОЛЛИ (US)
Петер КОННОЛЛИ
Уилль м В. МЮРРЭЙ (US)
Уилльям В. МЮРРЭЙ
Чандра Р. ШАХ (US)
Чандра Р. ШАХ
Брюс Е. МАРЬЯНОФФ (US)
Брюс Е. Марьянофф
Кимберли Б. УАЙТ (US)
Кимберли Б. УАЙТ
Лан ШЕН (US)
Лан Шен
Брюс КОНВЭЙ (US)
Брюс КОНВЭЙ
Кейт ДЕМАРЕСТ (US)
Кейт ДЕМАРЕСТ
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Орто-Макнейл Фармасьютикал, Инк.
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    • C07D471/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/22Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed systems contains four or more hetero rings
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    • C07D487/22Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains four or more hetero rings
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    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
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    • C07D498/22Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms in which the condensed system contains four or more hetero rings
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    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D515/00Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen, oxygen, and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00
    • C07D515/22Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen, oxygen, and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00 in which the condensed system contains four or more hetero rings

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  • Chemical & Material Sciences (AREA)
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  • Bioinformatics & Cheminformatics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
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  • Public Health (AREA)
  • Immunology (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Cardiology (AREA)
  • Diabetes (AREA)
  • Pain & Pain Management (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Dermatology (AREA)
  • Psychiatry (AREA)
  • Rheumatology (AREA)
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  • Hematology (AREA)
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RU2003120442/04A 2000-12-08 2001-12-06 Макрогетероциклические соединения RU2275373C2 (ru)

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US25416100P 2000-12-08 2000-12-08
US60/254,161 2000-12-08

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RU2003120442A RU2003120442A (ru) 2004-12-27
RU2275373C2 true RU2275373C2 (ru) 2006-04-27

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US (1) US6828327B2 (de)
EP (1) EP1345946B1 (de)
JP (1) JP2004526676A (de)
AT (1) ATE301661T1 (de)
AU (2) AU2002227371B2 (de)
CA (1) CA2431187A1 (de)
DE (1) DE60112611T2 (de)
ES (1) ES2245994T3 (de)
MX (1) MXPA03005139A (de)
RU (1) RU2275373C2 (de)
WO (1) WO2002046197A1 (de)

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
RU2518471C2 (ru) * 2008-08-14 2014-06-10 Тиботек Фармасьютикалз Макроциклические индольные производные, применимые в качестве ингибиторов вируса гепатита с
RU2630958C2 (ru) * 2015-12-29 2017-09-15 федеральное государственное автономное образовательное учреждение высшего образования "Московский физико-технический институт (государственный университет)" (МФТИ) Новые макроциклические соединения, содержащие природное 3,7-диазабицикло[3.3.1]нонановое ядро и способ их получения
RU2728579C2 (ru) * 2015-07-21 2020-07-30 Тёрнинг Поинт Терапьютикс, Инк. Хиральные диарильные макроциклы и их применение

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JP2009510085A (ja) * 2005-09-29 2009-03-12 ジヤンセン・フアーマシユーチカ・ナームローゼ・フエンノートシヤツプ キナーゼインヒビターとしての大型複素環式化合物
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MXPA03005139A (es) 2004-01-29
JP2004526676A (ja) 2004-09-02
WO2002046197A1 (en) 2002-06-13
ATE301661T1 (de) 2005-08-15
DE60112611T2 (de) 2006-06-14
EP1345946A1 (de) 2003-09-24
DE60112611D1 (de) 2005-09-15
HK1055956A1 (en) 2004-01-30
US6828327B2 (en) 2004-12-07
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US20030078280A1 (en) 2003-04-24
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