SE7706673L - Forfarande for framstellning av flerfaldigt halogenerade steroider - Google Patents

Forfarande for framstellning av flerfaldigt halogenerade steroider

Info

Publication number: SE7706673L
Authority: SE; Sweden
Prior art keywords: alpha; halogenerated; steroids; procedure; chlorine
Prior art date: 1976-09-29

Application number

SE7706673A

Other languages

Unknown language ( )

English (en)

Other versions

SE436751B (sv

Inventor

J Kalvoda

G Anner

Original Assignee

Ciba Geigy Ag

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1976-09-29

Filing date

1977-06-08

Publication date

1978-03-30

1977-06-08 Application filed by Ciba Geigy Ag filed Critical Ciba Geigy Ag

1978-03-30 Publication of SE7706673L publication Critical patent/SE7706673L/sv

1985-01-21 Publication of SE436751B publication Critical patent/SE436751B/sv

Links

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J7/00—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms
- C07J7/008—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms substituted in position 21
- C07J7/0085—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms substituted in position 21 by an halogen atom
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J21/00—Normal steroids containing carbon, hydrogen, halogen or oxygen having an oxygen-containing hetero ring spiro-condensed with the cyclopenta(a)hydrophenanthrene skeleton
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J31/00—Normal steroids containing one or more sulfur atoms not belonging to a hetero ring
- C07J31/006—Normal steroids containing one or more sulfur atoms not belonging to a hetero ring not covered by C07J31/003
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J5/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond
- C07J5/0046—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond substituted in position 17 alfa
- C07J5/0061—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond substituted in position 17 alfa substituted in position 16
- C07J5/0069—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond substituted in position 17 alfa substituted in position 16 by a saturated or unsaturated hydrocarbon group
- C07J5/0076—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond substituted in position 17 alfa substituted in position 16 by a saturated or unsaturated hydrocarbon group by an alkyl group
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J71/00—Steroids in which the cyclopenta(a)hydrophenanthrene skeleton is condensed with a heterocyclic ring
- C07J71/0005—Oxygen-containing hetero ring
- C07J71/001—Oxiranes
- C07J71/0015—Oxiranes at position 9(11)

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
General Health & Medical Sciences (AREA)
Medicinal Chemistry (AREA)
Life Sciences & Earth Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Pain & Pain Management (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Pharmacology & Pharmacy (AREA)
Rheumatology (AREA)
Animal Behavior & Ethology (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Steroid Compounds (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

SE7706673A 1976-09-29 1977-06-08 Forfarande enligt krav 1 i patentet 7613920-3 (publ.nr 423903) for framstellning av 17alfa-acyloxi-9alfa, 21-dihalogen-11beta-hydroxi-6alfa-fluor-16beta-metyl-pregna-1,4-dien-3,20-dion-foreningar SE436751B (sv)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
LU75903A LU75903A1 (sv)	1976-09-29	1976-09-29

Publications (2)

Publication Number	Publication Date
SE7706673L true SE7706673L (sv)	1978-03-30
SE436751B SE436751B (sv)	1985-01-21

Family

ID=19728370

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
SE7706673A SE436751B (sv)	1976-09-29	1977-06-08	Forfarande enligt krav 1 i patentet 7613920-3 (publ.nr 423903) for framstellning av 17alfa-acyloxi-9alfa, 21-dihalogen-11beta-hydroxi-6alfa-fluor-16beta-metyl-pregna-1,4-dien-3,20-dion-foreningar

Country Status (24)

Country	Link
JP (1)	JPS5356652A (sv)
AT (3)	AT363197B (sv)
AU (1)	AU514200B2 (sv)
BE (1)	BE859120A (sv)
CA (1)	CA1101410A (sv)
CH (9)	CH624967A5 (sv)
CY (1)	CY1178A (sv)
DD (1)	DD133150A5 (sv)
DE (1)	DE2743069C2 (sv)
DK (1)	DK146017C (sv)
ES (1)	ES462763A1 (sv)
FR (1)	FR2366311A1 (sv)
GB (1)	GB1563638A (sv)
HK (1)	HK16683A (sv)
HU (1)	HU175218B (sv)
IE (1)	IE46047B1 (sv)
IL (1)	IL53012A (sv)
KE (1)	KE3258A (sv)
LU (1)	LU75903A1 (sv)
MY (1)	MY8400092A (sv)
NL (1)	NL7710089A (sv)
SE (1)	SE436751B (sv)
SG (1)	SG3383G (sv)
ZA (1)	ZA775800B (sv)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
NL187577C (nl) *	1978-04-05	1991-11-18	Sibla Srl	3-acetoxy-9beta,11beta-epoxy-pregna-1,3,5-trienen, werkwijze voor de bereiding daarvan en werkwijze voor de bereiding van 6alfa-halogeen-pregna-1,4-dieen-3-onen.
DE3227312A1 (de) *	1982-07-19	1984-01-19	Schering AG, 1000 Berlin und 4709 Bergkamen	Neue 6,16-dimethylkortikoide, ihre herstellung und verwendung
EP0523132A1 (en) *	1990-03-27	1993-01-20	Schering Corporation	PROCESS FOR 9$g(a)-HYDROXY STEROID DEHYDRATION
US5972922A (en) *	1990-06-11	1999-10-26	Alcon Laboratories, Inc.	Steroids which inhibit angiogenesis
AU2002359523A1 (en)	2001-11-29	2003-06-17	Taro Pharmaceuticals U.S.A., Inc.	Method for the preparation of 6-alpha-fluoro corticosteroids
US8809307B2 (en)	2010-11-22	2014-08-19	Dow Pharmaceutical Sciences, Inc.	Pharmaceutical formulations containing corticosteroids for topical administration
US11957753B2 (en)	2010-11-22	2024-04-16	Bausch Health Ireland Limited	Pharmaceutical formulations containing corticosteroids for topical administration
JP6997624B2 (ja)	2015-06-18	2022-01-17	ボシュヘルスユーエス，エルエルシー．	乾癬を治療するためのコルチコステロイドおよびレチノイドを含む局所用組成物
US11311482B2 (en)	2017-05-12	2022-04-26	Bausch Health Us, Llc	Topical compositions and methods for treating skin diseases

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
GB898292A (en) *	1959-03-18	1962-06-06	Upjohn Co	Improvements in or relating to steroids and the manufacture thereof
US3644340A (en) *	1970-03-19	1972-02-22	Syntex Corp	Preparation of 21-chloro steroids
US3992422A (en) *	1975-08-14	1976-11-16	Schering Corporation	Process for the preparation of 21-halogeno-21-desoxy-17α-acyloxy-20-keto-pregnenes

1976
- 1976-09-29 LU LU75903A patent/LU75903A1/xx unknown
- 1976-12-09 CH CH1549976A patent/CH624967A5/de not_active IP Right Cessation
1977
- 1977-06-08 SE SE7706673A patent/SE436751B/sv not_active IP Right Cessation
- 1977-06-09 DK DK256977A patent/DK146017C/da not_active IP Right Cessation
- 1977-09-14 NL NL7710089A patent/NL7710089A/xx not_active Application Discontinuation
- 1977-09-24 DE DE2743069A patent/DE2743069C2/de not_active Expired
- 1977-09-26 CH CH1172177A patent/CH632279A5/de not_active IP Right Cessation
- 1977-09-27 FR FR7729043A patent/FR2366311A1/fr active Granted
- 1977-09-27 DD DD7700201226A patent/DD133150A5/xx unknown
- 1977-09-27 CY CY1178A patent/CY1178A/xx unknown
- 1977-09-27 CA CA287,560A patent/CA1101410A/en not_active Expired
- 1977-09-27 AU AU29148/77A patent/AU514200B2/en not_active Expired
- 1977-09-27 GB GB40131/77A patent/GB1563638A/en not_active Expired
- 1977-09-28 ZA ZA00775800A patent/ZA775800B/xx unknown
- 1977-09-28 IE IE1979/77A patent/IE46047B1/en not_active IP Right Cessation
- 1977-09-28 HU HU77CI1774A patent/HU175218B/hu unknown
- 1977-09-28 BE BE181243A patent/BE859120A/xx not_active IP Right Cessation
- 1977-09-28 AT AT0691077A patent/AT363197B/de not_active IP Right Cessation
- 1977-09-28 IL IL53012A patent/IL53012A/xx unknown
- 1977-09-29 JP JP11619377A patent/JPS5356652A/ja active Granted
- 1977-09-29 ES ES462763A patent/ES462763A1/es not_active Expired
1979
- 1979-02-28 AT AT0151379A patent/AT363203B/de not_active IP Right Cessation
- 1979-02-28 AT AT0151279A patent/AT363202B/de not_active IP Right Cessation
1980
- 1980-11-18 CH CH853980A patent/CH625810A5/de not_active IP Right Cessation
- 1980-11-18 CH CH853880A patent/CH625809A5/de not_active IP Right Cessation
- 1980-11-18 CH CH853780A patent/CH625808A5/de not_active IP Right Cessation
1981
- 1981-10-26 CH CH683281A patent/CH632000A5/de not_active IP Right Cessation
- 1981-10-26 CH CH683081A patent/CH631998A5/de not_active IP Right Cessation
- 1981-10-26 CH CH683181A patent/CH631999A5/de not_active IP Right Cessation
1982
- 1982-01-06 CH CH4682A patent/CH632521A5/de not_active IP Right Cessation
1983
- 1983-01-20 SG SG33/83A patent/SG3383G/en unknown
- 1983-01-21 KE KE3258A patent/KE3258A/xx unknown
- 1983-05-19 HK HK166/83A patent/HK16683A/en not_active IP Right Cessation
1984
- 1984-12-30 MY MY92/84A patent/MY8400092A/xx unknown

Also Published As

Publication number	Publication date
JPS6214557B2 (sv)	1987-04-02
CH631998A5 (en)	1982-09-15
DK146017C (da)	1983-10-24
HK16683A (en)	1983-05-27
ATA151279A (de)	1980-12-15
LU75903A1 (sv)	1978-05-16
SG3383G (en)	1983-09-09
CH631999A5 (en)	1982-09-15
DK256977A (da)	1978-03-30
CH625810A5 (en)	1981-10-15
CA1101410A (en)	1981-05-19
KE3258A (en)	1983-03-04
SE436751B (sv)	1985-01-21
BE859120A (fr)	1978-03-28
DK146017B (da)	1983-05-24
ES462763A1 (es)	1978-05-16
IL53012A (en)	1982-05-31
IE46047B1 (en)	1983-02-09
CY1178A (en)	1983-06-10
FR2366311B1 (sv)	1982-12-03
DE2743069A1 (de)	1978-03-30
IL53012A0 (en)	1977-11-30
CH632279A5 (en)	1982-09-30
CH625809A5 (en)	1981-10-15
FR2366311A1 (fr)	1978-04-28
AT363197B (de)	1981-07-10
AT363202B (de)	1981-07-27
DE2743069C2 (de)	1987-03-05
HU175218B (hu)	1980-06-28
ATA691077A (de)	1980-12-15
AU514200B2 (en)	1981-01-29
DD133150A5 (de)	1978-12-13
CH632521A5 (en)	1982-10-15
JPS5356652A (en)	1978-05-23
NL7710089A (nl)	1978-03-31
AU2914877A (en)	1979-04-05
ZA775800B (en)	1978-08-30
AT363203B (de)	1981-07-27
CH625808A5 (en)	1981-10-15
IE46047L (en)	1978-03-29
ATA151379A (de)	1980-12-15
CH624967A5 (en)	1981-08-31
GB1563638A (en)	1980-03-26
MY8400092A (en)	1984-12-31
CH632000A5 (en)	1982-09-15

Legal Events

Date

Code

Title

Description

1995-01-31

NAL

Patent in force

Ref document number: 7706673-6

Format of ref document f/p: F

1997-03-03

NUG

Patent has lapsed