SE7707633L - Forfarande for stereoselektiv framstellning av hexahydrodibensopyranoner smat mellanprodukter derfor - Google Patents

Forfarande for stereoselektiv framstellning av hexahydrodibensopyranoner smat mellanprodukter derfor

Info

Publication number: SE7707633L
Authority: SE; Sweden
Prior art keywords: dimethyl; optically active; substituted; hexahydrodibensopyranons; smat
Prior art date: 1976-11-10

Application number

SE7707633A

Other languages

English (en)

Other versions

SE428020B (sv

Inventor

R A Archer

W A Day

Original Assignee

Lilly Co Eli

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1976-11-10

Filing date

1977-06-30

Publication date

1978-05-11

1977-06-30 Application filed by Lilly Co Eli filed Critical Lilly Co Eli

1978-05-11 Publication of SE7707633L publication Critical patent/SE7707633L/sv

1983-05-30 Publication of SE428020B publication Critical patent/SE428020B/sv

Links

239000013067 intermediate product Substances 0.000 title 1
230000000707 stereoselective effect Effects 0.000 title 1
-1 4-(4-substituted-2,6-dihydroxyphenyl)-6,6-dimethyl-2-norpinanone Chemical class 0.000 abstract 3
230000003287 optical effect Effects 0.000 abstract 2
YFJDGZZRPOYOFP-UHFFFAOYSA-N (4-acetyloxy-6,6-dimethyl-2-bicyclo[3.1.1]hept-3-enyl) acetate Chemical compound CC(=O)OC1C=C(OC(C)=O)C2C(C)(C)C1C2 YFJDGZZRPOYOFP-UHFFFAOYSA-N 0.000 abstract 1
TUJQDYIBTVJMMM-UHFFFAOYSA-N (4-acetyloxy-6,6-dimethyl-4-bicyclo[3.1.1]hept-2-enyl) acetate Chemical compound CC(=O)OC1(OC(C)=O)C=CC2C(C)(C)C1C2 TUJQDYIBTVJMMM-UHFFFAOYSA-N 0.000 abstract 1
239000002841 Lewis acid Substances 0.000 abstract 1
239000002253 acid Substances 0.000 abstract 1
150000001591 beta-pinene derivatives Chemical class 0.000 abstract 1
150000001875 compounds Chemical class 0.000 abstract 1
150000007517 lewis acids Chemical class 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C49/00—Ketones; Ketenes; Dimeric ketenes; Ketonic chelates
- C07C49/587—Unsaturated compounds containing a keto groups being part of a ring
- C07C49/703—Unsaturated compounds containing a keto groups being part of a ring containing hydroxy groups
- C07C49/747—Unsaturated compounds containing a keto groups being part of a ring containing hydroxy groups containing six-membered aromatic rings
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
- C07C45/51—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by pyrolysis, rearrangement or decomposition
- C07C45/54—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by pyrolysis, rearrangement or decomposition of compounds containing doubly bound oxygen atoms, e.g. esters
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
- C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D311/78—Ring systems having three or more relevant rings
- C07D311/80—Dibenzopyrans; Hydrogenated dibenzopyrans

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Pyrane Compounds (AREA)
Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
Saccharide Compounds (AREA)
Nitrogen- Or Sulfur-Containing Heterocyclic Ring Compounds With Rings Of Six Or More Members (AREA)

SE7707633A 1976-11-10 1977-06-30 Forfarande for framstellning av optiskt aktiva isomerer av 3-substituerade cis- och trans-1-hydroxi-6,6-dimetyl-6,6a-7,8,10,10a-hexahydro-9h-dibenso(b,d)-pyran-9-oner SE428020B (sv)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
US05/740,502 US4102902A (en)	1976-11-10	1976-11-10	Stereoselective preparation of hexahydro dibenzopyranones and intermediates therefor

Publications (2)

Publication Number	Publication Date
SE7707633L true SE7707633L (sv)	1978-05-11
SE428020B SE428020B (sv)	1983-05-30

Family

ID=24976773

Family Applications (3)

Application Number	Title	Priority Date	Filing Date
SE7707633A SE428020B (sv)	1976-11-10	1977-06-30	Forfarande for framstellning av optiskt aktiva isomerer av 3-substituerade cis- och trans-1-hydroxi-6,6-dimetyl-6,6a-7,8,10,10a-hexahydro-9h-dibenso(b,d)-pyran-9-oner
SE8005314A SE8005314L (sv)	1976-11-10	1980-07-22	Forfarande for framstellning av en joptisk aktiv norpinenforening
SE8005316A SE434510B (sv)	1976-11-10	1980-07-22	Substituerad 4-(2,6-dihydroxifenyl)-6,6-dimetyl-2-norpinanon till anvendning som mellanprodukt

Family Applications After (2)

Application Number	Title	Priority Date	Filing Date
SE8005314A SE8005314L (sv)	1976-11-10	1980-07-22	Forfarande for framstellning av en joptisk aktiv norpinenforening
SE8005316A SE434510B (sv)	1976-11-10	1980-07-22	Substituerad 4-(2,6-dihydroxifenyl)-6,6-dimetyl-2-norpinanon till anvendning som mellanprodukt

Country Status (30)

Country	Link
US (1)	US4102902A (sv)
JP (2)	JPS5925792B2 (sv)
AT (1)	AT356103B (sv)
AU (1)	AU509355B2 (sv)
BE (1)	BE856413A (sv)
BG (2)	BG28411A4 (sv)
CA (1)	CA1101875A (sv)
CH (2)	CH632506A5 (sv)
CS (1)	CS196376B2 (sv)
DD (2)	DD134350A5 (sv)
DE (3)	DE2760006C2 (sv)
DK (1)	DK301477A (sv)
ES (3)	ES460389A1 (sv)
FR (1)	FR2370742A1 (sv)
GB (2)	GB1584182A (sv)
GR (1)	GR66417B (sv)
HU (2)	HU183286B (sv)
IE (1)	IE45247B1 (sv)
IL (3)	IL52427A (sv)
MX (1)	MX5172E (sv)
NL (1)	NL7707467A (sv)
NZ (1)	NZ184526A (sv)
PH (3)	PH13827A (sv)
PL (2)	PL104356B1 (sv)
PT (1)	PT66746B (sv)
RO (1)	RO78780A (sv)
SE (3)	SE428020B (sv)
SU (2)	SU786898A3 (sv)
YU (1)	YU163677A (sv)
ZA (1)	ZA773960B (sv)

Families Citing this family (29)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
IL55274A (en) *	1978-08-02	1982-08-31	Yissum Res Dev Co	4-(2,6-dihydroxy-4-(dimethylheptyl)phenyl)substituted 2-pinen-10-ol and pinane derivatives,their preparation and pharmaceutical compositions comprising them
US4939169A (en) *	1985-09-20	1990-07-03	The Upjohn Company	1,4-naphthalenediol and 1,4-hydroquinone derivatives
US4851586A (en) *	1985-09-20	1989-07-25	The Upjohn Company	1,4-naphthalenediol and 1,4-hydroquinone derivatives
IL80411A (en) *	1986-10-24	1991-08-16	Raphael Mechoulam	Preparation of dibenzopyranol derivatives and pharmaceutical compositions containing them
JPH0315035A (ja) *	1989-03-03	1991-01-23	Konica Corp	カメラ
JP2577671B2 (ja) *	1990-06-11	1997-02-05	高砂熱学工業株式会社	気化式精密加湿装置
CA2340445A1 (en) *	1998-05-04	1999-11-11	The University Of Connecticut	Novel analgesic and immunomodulatory cannabinoids
US7589220B2 (en) *	1998-06-09	2009-09-15	University Of Connecticut	Inhibitors of the anandamide transporter
US7897598B2 (en) *	1998-06-09	2011-03-01	Alexandros Makriyannis	Inhibitors of the anandamide transporter
US7276613B1 (en)	1998-11-24	2007-10-02	University Of Connecticut	Retro-anandamides, high affinity and stability cannabinoid receptor ligands
US7161016B1 (en)	1998-11-24	2007-01-09	University Of Connecticut	Cannabimimetic lipid amides as useful medications
US6900236B1 (en)	1999-10-18	2005-05-31	University Of Connecticut	Cannabimimetic indole derivatives
US7119108B1 (en)	1999-10-18	2006-10-10	University Of Connecticut	Pyrazole derivatives as cannabinoid receptor antagonists
WO2001028329A1 (en)	1999-10-18	2001-04-26	University Of Connecticut	Peripheral cannabinoid receptor (cb2) selective ligands
US7393842B2 (en) *	2001-08-31	2008-07-01	University Of Connecticut	Pyrazole analogs acting on cannabinoid receptors
US8084467B2 (en) *	1999-10-18	2011-12-27	University Of Connecticut	Pyrazole derivatives as cannabinoid receptor antagonists
MXPA02005104A (es) *	1999-10-18	2003-09-25	Alexipharma Inc	Agonistas novedosos de canabinoide biciclico para el receptor canabinoide.
US7741365B2 (en) *	1999-10-18	2010-06-22	University Of Connecticut	Peripheral cannabinoid receptor (CB2) selective ligands
US6943266B1 (en) *	1999-10-18	2005-09-13	University Of Connecticut	Bicyclic cannabinoid agonists for the cannabinoid receptor
US7329651B2 (en) *	2001-01-26	2008-02-12	University Of Connecticut	Cannabimimetic ligands
WO2002060447A1 (en)	2001-01-29	2002-08-08	University Of Connecticut	Receptor selective cannabimimetic aminoalkylindoles
WO2003005960A2 (en) *	2001-07-13	2003-01-23	University Of Connecticut	Novel bicyclic and tricyclic cannabinoids
WO2003035005A2 (en) *	2001-10-26	2003-05-01	University Of Connecticut	Heteroindanes: a new class of potent cannabimimetic ligands
US7285687B2 (en) *	2002-04-25	2007-10-23	Virginia Commonwealth University	Cannabinoids
AU2003265663A1 (en)	2002-08-23	2004-03-11	University Of Connecticut	Keto cannabinoids with therapeutic indications
EP2578561A1 (en)	2005-09-29	2013-04-10	Albany Molecular Research, Inc.	Processes for the production of cannabidiol derivatives and intermediates thereof
US9763894B2 (en) *	2006-12-05	2017-09-19	Virginia Commonwealth University	Inflammation therapy
PL222532B1 (pl)	2012-04-05	2016-08-31	Akademia Morska W Szczecinie	Sposób i układ do diagnozowania układu wtryskowego silników o zapłonie samoczynnym, zwłaszcza silników okrętowych
US12029718B2 (en)	2021-11-09	2024-07-09	Cct Sciences, Llc	Process for production of essentially pure delta-9-tetrahydrocannabinol

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US3856821A (en) *	1973-07-18	1974-12-24	Smithkline Corp	ALKOXY DIBENZO (b,d) PYRANS
US3856820A (en) *	1973-07-18	1974-12-24	Smithkline Corp	2-AMINOMETHYL DIBENZO (b,d) PYRANS
US3856822A (en) *	1973-07-18	1974-12-24	Smithkline Corp	3-alkenyl dibenzo (b,d)pyrans
US3928598A (en) *	1973-11-05	1975-12-23	Lilly Co Eli	Hexahydro-dibenzo{8 b,d{9 pyran-9-ones as an anti-anxiety drug

1976
- 1976-11-10 US US05/740,502 patent/US4102902A/en not_active Expired - Lifetime
1977
- 1977-06-29 GB GB1144/80A patent/GB1584182A/en not_active Expired
- 1977-06-29 GB GB27138/77A patent/GB1584181A/en not_active Expired
- 1977-06-30 PH PH19935A patent/PH13827A/en unknown
- 1977-06-30 SE SE7707633A patent/SE428020B/sv not_active IP Right Cessation
- 1977-06-30 PT PT66746A patent/PT66746B/pt unknown
- 1977-06-30 ZA ZA00773960A patent/ZA773960B/xx unknown
- 1977-06-30 NZ NZ184526A patent/NZ184526A/xx unknown
- 1977-06-30 CA CA281,784A patent/CA1101875A/en not_active Expired
- 1977-06-30 IL IL52427A patent/IL52427A/xx unknown
- 1977-07-01 DE DE2760006A patent/DE2760006C2/de not_active Expired
- 1977-07-01 DE DE2729859A patent/DE2729859C2/de not_active Expired
- 1977-07-01 DE DE2760005A patent/DE2760005C2/de not_active Expired
- 1977-07-01 AU AU26684/77A patent/AU509355B2/en not_active Expired
- 1977-07-01 YU YU01636/77A patent/YU163677A/xx unknown
- 1977-07-01 BG BG037819A patent/BG28411A4/xx unknown
- 1977-07-01 BG BG036778A patent/BG28061A3/xx unknown
- 1977-07-04 ES ES460389A patent/ES460389A1/es not_active Expired
- 1977-07-04 JP JP52081489A patent/JPS5925792B2/ja not_active Expired
- 1977-07-04 CH CH819477A patent/CH632506A5/de not_active IP Right Cessation
- 1977-07-04 PL PL1977199362A patent/PL104356B1/pl unknown
- 1977-07-04 ES ES460388A patent/ES460388A1/es not_active Expired
- 1977-07-04 MX MX775872U patent/MX5172E/es unknown
- 1977-07-04 SU SU772497362A patent/SU786898A3/ru active
- 1977-07-04 PL PL1977206420A patent/PL104432B1/pl unknown
- 1977-07-04 BE BE1008247A patent/BE856413A/xx not_active IP Right Cessation
- 1977-07-04 ES ES460387A patent/ES460387A1/es not_active Expired
- 1977-07-05 DD DD77199899A patent/DD134350A5/xx unknown
- 1977-07-05 GR GR53879A patent/GR66417B/el unknown
- 1977-07-05 RO RO7798966A patent/RO78780A/ro unknown
- 1977-07-05 NL NL7707467A patent/NL7707467A/xx not_active Application Discontinuation
- 1977-07-05 IE IE1389/77A patent/IE45247B1/en unknown
- 1977-07-05 HU HU81113A patent/HU183286B/hu unknown
- 1977-07-05 HU HU77EI755A patent/HU177308B/hu unknown
- 1977-07-05 DD DD77208796A patent/DD140455A5/de unknown
- 1977-07-05 FR FR7720645A patent/FR2370742A1/fr active Granted
- 1977-07-05 DK DK301477A patent/DK301477A/da not_active Application Discontinuation
- 1977-07-06 AT AT483677A patent/AT356103B/de not_active IP Right Cessation
- 1977-07-06 CS CS774518A patent/CS196376B2/cs unknown
- 1977-10-28 PH PH20382A patent/PH14708A/en unknown
- 1977-10-28 PH PH20381A patent/PH13890A/en unknown
1978
- 1978-07-06 SU SU782633652A patent/SU1128829A3/ru active
1980
- 1980-07-15 IL IL60589A patent/IL60589A0/xx unknown
- 1980-07-15 IL IL60590A patent/IL60590A0/xx unknown
- 1980-07-22 SE SE8005314A patent/SE8005314L/sv not_active Application Discontinuation
- 1980-07-22 SE SE8005316A patent/SE434510B/sv unknown
1982
- 1982-02-05 CH CH71882A patent/CH632481A5/de not_active IP Right Cessation
- 1982-04-16 JP JP57064621A patent/JPS5912654B2/ja not_active Expired

Also Published As

Publication number	Publication date
SE8005314L (sv)	1980-07-22
DE2729859A1 (de)	1978-05-11
CS196376B2 (en)	1980-03-31
SU1128829A3 (ru)	1984-12-07
YU163677A (en)	1982-10-31
SE8005316L (sv)	1980-07-22
DE2729859C2 (de)	1984-08-23
AU509355B2 (en)	1980-05-08
DE2760005C2 (de)	1984-04-26
SE434510B (sv)	1984-07-30
ZA773960B (en)	1979-02-28
CH632481A5 (de)	1982-10-15
PL104356B1 (pl)	1979-08-31
IL60590A0 (en)	1980-09-16
PT66746B (en)	1978-11-27
FR2370742B1 (sv)	1980-12-26
CH632506A5 (de)	1982-10-15
JPS5925792B2 (ja)	1984-06-21
ES460387A1 (es)	1978-04-01
HU183286B (en)	1984-04-28
PH13890A (en)	1980-10-27
AU2668477A (en)	1979-01-04
GR66417B (sv)	1981-03-20
IE45247L (en)	1978-05-10
NZ184526A (en)	1979-03-16
PT66746A (en)	1977-07-01
FR2370742A1 (fr)	1978-06-09
JPS5912654B2 (ja)	1984-03-24
PL199362A1 (pl)	1978-05-22
RO78780A (ro)	1982-04-12
PH13827A (en)	1980-10-07
IL60589A0 (en)	1980-09-16
PL104432B1 (pl)	1979-08-31
DE2760006C2 (de)	1985-07-04
CA1101875A (en)	1981-05-26
MX5172E (es)	1983-04-18
SE428020B (sv)	1983-05-30
AT356103B (de)	1980-04-10
NL7707467A (nl)	1978-05-12
BG28061A3 (en)	1980-02-25
IL52427A (en)	1981-10-30
ES460388A1 (es)	1978-04-01
ATA483677A (de)	1979-09-15
DD134350A5 (de)	1979-02-21
GB1584182A (en)	1981-02-11
ES460389A1 (es)	1978-04-16
SU786898A3 (ru)	1980-12-07
JPS5359670A (en)	1978-05-29
DK301477A (da)	1978-05-11
IL52427A0 (en)	1977-08-31
BG28411A4 (en)	1980-04-15
JPS5865244A (ja)	1983-04-18
US4102902A (en)	1978-07-25
IE45247B1 (en)	1982-07-14
HU177308B (en)	1981-09-28
BE856413A (fr)	1978-01-04
GB1584181A (en)	1981-02-11
DD140455A5 (de)	1980-03-05
PH14708A (en)	1981-11-13

Legal Events

Date

Code

Title

Description

1995-01-31

NUG

Patent has lapsed

Ref document number: 7707633-9

Effective date: 19900702

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Publication	Publication Date	Title
IE45247L (en)	1978-05-10	Preparing dibenzopyranones from norpinanones
ATE44528T1 (de)	1989-07-15	Arzneimittel mit antipsychotischer wirkung.
ES2083392T3 (es)	1996-04-16	Sustancia pf 1022, procedimiento para su preparacion y composicion antihelmintica que contiene esta sustancia.
ES477520A1 (es)	1979-06-01	Procedimiento para la preparacion de nuevas penicilinas.
NO155548C (no)	1987-04-15	Fremgangsmaate til fremstilling av optisk aktive cefalosporin-analoger.
OA06486A (fr)	1981-07-31	Procédé de préparation de 9 aminoalkylfluorènes.
GB2031896B (en)	1983-03-23	Process for the optical resolution of d,l-2-amino-4-methylphosphinobutyric acid
FR2458533B1 (sv)	1983-07-18
AR241108A2 (es)	1991-11-15	Insecticidas piretroides, acidos ciclopropancarboxilicos y esteres intermediarios y sus precedimientos de preparacion
SE7706310L (sv)	1977-12-02	Omega-nor-aromatiska-13,14-dehydro-prostaglandiner och forfarande for framstellning av dem
OA06274A (fr)	1981-06-30	Procédé de préparation de nouveaux composés de type muramyl-péptide.
NO794199L (no)	1980-07-14	Fremgangsmaate for fremstilling av spinnflor.
OA06355A (fr)	1981-06-30	Procédé de préparation de 3-exométhylènecépham-sulfoxydes.
IT1165188B (it)	1987-04-22	Procedimento per la preparazione dei monocarioni mediante dedicariotizzazione dei ceppi dicariotici di basidiomiceti
ES498016A0 (es)	1984-06-16	Procedimiento para la produccion de compuestos que contienen clorotriacinilo.
FR2389624A1 (sv)	1978-12-01
FR2369288A1 (fr)	1978-05-26	Procede de preparation de composes organiques d'etain
ES483284A1 (es)	1980-09-01	Un procedimiento para la preparacion de nuevas dibenzo (a,d)ciclohepten-5,10-iminas sustituidas
IT8025223A0 (it)	1980-10-09	Procedimento per la produzione di derivati dell'acido penicillanico.
IT1164907B (it)	1987-04-15	Procedimento per la produzione di cefalosporine
FR2446841A1 (fr)	1980-08-14	Procede de preparation de 1a,3b-dihydroxy-d5-steroides
OA06451A (fr)	1981-07-31	Procédé de préparation de composés B-lactame.
UA3421C1 (uk)	1991-06-15	Спосіб одержання похідних 2-тіазолідінону
FR2434158A1 (fr)	1980-03-21	Nouveaux derives de 1,3-benzoxazine-2,4-dione, leur preparation et leur application en tant que medicaments
SE7706083L (sv)	1978-11-25	Bicykliska laktondiolderivat jemte sett for deras framstellning