SE7809187L - Iminer - Google Patents

Iminer

Info

Publication number: SE7809187L
Authority: SE; Sweden
Prior art keywords: iminer
Prior art date: 1977-09-19

Application number

SE7809187A

Other languages

English (en)

Other versions

SE437520B (sv

Inventor

P S Anderson

M E Christy

B E Evans

Original Assignee

Merck & Co Inc

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1977-09-19

Filing date

1978-08-31

Publication date

1979-03-20

1978-08-31 Application filed by Merck & Co Inc filed Critical Merck & Co Inc

1979-03-20 Publication of SE7809187L publication Critical patent/SE7809187L/sv

1985-03-04 Publication of SE437520B publication Critical patent/SE437520B/sv

Links

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
- C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
- C07D295/08—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms
- C07D295/096—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms with the ring nitrogen atoms and the oxygen or sulfur atoms separated by carbocyclic rings or by carbon chains interrupted by carbocyclic rings
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P21/00—Drugs for disorders of the muscular or neuromuscular system
- A61P21/02—Muscle relaxants, e.g. for tetanus or cramps
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/20—Hypnotics; Sedatives
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/22—Anxiolytics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
- C07C45/56—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds from heterocyclic compounds
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
- C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
- C07D295/10—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by doubly bound oxygen or sulphur atoms
- C07D295/112—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by doubly bound oxygen or sulphur atoms with the ring nitrogen atoms and the doubly bound oxygen or sulfur atoms separated by carbocyclic rings or by carbon chains interrupted by carbocyclic rings
- C07D295/116—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by doubly bound oxygen or sulphur atoms with the ring nitrogen atoms and the doubly bound oxygen or sulfur atoms separated by carbocyclic rings or by carbon chains interrupted by carbocyclic rings with the doubly bound oxygen or sulfur atoms directly attached to a carbocyclic ring
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D451/00—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof
- C07D451/02—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof containing not further condensed 8-azabicyclo [3.2.1] octane or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane; Cyclic acetals thereof

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
General Health & Medical Sciences (AREA)
Veterinary Medicine (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Bioinformatics & Cheminformatics (AREA)
Pharmacology & Pharmacy (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
Engineering & Computer Science (AREA)
Public Health (AREA)
Chemical Kinetics & Catalysis (AREA)
Neurology (AREA)
Biomedical Technology (AREA)
Neurosurgery (AREA)
Anesthesiology (AREA)
Pain & Pain Management (AREA)
Orthopedic Medicine & Surgery (AREA)
Physical Education & Sports Medicine (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)

SE7809187A 1977-09-19 1978-08-31 Dibensocyklohepteniminer, forfarande for framstellning av dessa och farmaceutisk komposition SE437520B (sv)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
US83463977A	1977-09-19	1977-09-19

Publications (2)

Publication Number	Publication Date
SE7809187L true SE7809187L (sv)	1979-03-20
SE437520B SE437520B (sv)	1985-03-04

Family

ID=25267426

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
SE7809187A SE437520B (sv)	1977-09-19	1978-08-31	Dibensocyklohepteniminer, forfarande for framstellning av dessa och farmaceutisk komposition

Country Status (33)

Country	Link
JP (1)	JPS5463100A (sv)
AR (1)	AR231544A1 (sv)
AT (1)	AT370103B (sv)
AU (1)	AU520178B2 (sv)
BE (1)	BE870562A (sv)
CA (1)	CA1129850A (sv)
CH (1)	CH637954A5 (sv)
CY (1)	CY1283A (sv)
DE (1)	DE2840786A1 (sv)
DK (1)	DK153843C (sv)
ES (7)	ES473492A1 (sv)
FI (1)	FI65618C (sv)
FR (1)	FR2403334A1 (sv)
GB (2)	GB2061947B (sv)
GR (1)	GR65703B (sv)
HK (1)	HK30885A (sv)
HU (1)	HU180868B (sv)
IE (1)	IE47355B1 (sv)
IL (1)	IL55521A0 (sv)
IT (1)	IT1113279B (sv)
KE (1)	KE3501A (sv)
LU (1)	LU80262A1 (sv)
NL (1)	NL191488C (sv)
NO (1)	NO151861C (sv)
NZ (1)	NZ188361A (sv)
PH (1)	PH15920A (sv)
PL (3)	PL121605B1 (sv)
PT (1)	PT68544A (sv)
SE (1)	SE437520B (sv)
SG (1)	SG9585G (sv)
SU (2)	SU895288A3 (sv)
YU (1)	YU41432B (sv)
ZA (1)	ZA785291B (sv)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US4232158A (en) *	1979-06-04	1980-11-04	Merck & Co., Inc.	10,11-Dihydro-5H-dibenzo[a,d]cyclohepten-5,10-imines
US4477668A (en) *	1982-04-07	1984-10-16	Merck & Co., Inc.	Process for 5-methyl-10,11-dihydro-5H-dibenzo[a,d]-cyclohepten-5,10-imine
GB8719199D0 (en) *	1987-08-13	1987-09-23	Merck Sharp & Dohme	Chemical compounds
US5686614A (en) *	1995-04-11	1997-11-11	Neurogen Corporation	Preparation of chiral 5-aminocarbonyl-5H-dibenzo a,d!cyclohepten-5,10-imines by optical resolution
US5739337A (en) *	1996-03-08	1998-04-14	Neurogen Corporation	Process for preparing dibenzo-1-carboxamido-1,4-azabicyclo 3.2.1!octanes
WO2017093354A1 (en)	2015-11-30	2017-06-08	INSERM (Institut National de la Santé et de la Recherche Médicale)	Nmdar antagonists for the treatment of diseases associated with angiogenesis

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
BE794904A (fr) *	1972-02-04	1973-08-02	Roussel Uclaf	Nouveaux derives du dibenzocycloheptene et leur preparation
BE829075A (fr) *	1974-05-15	1975-11-14		9,10-dihydroanthracen-9,10-imines substituees et leurs analogues heterocycliques (aza)

1978
- 1978-08-28 NL NL7808847A patent/NL191488C/xx not_active IP Right Cessation
- 1978-08-31 SE SE7809187A patent/SE437520B/sv not_active IP Right Cessation
- 1978-09-01 FI FI782680A patent/FI65618C/fi not_active IP Right Cessation
- 1978-09-04 DK DK389978A patent/DK153843C/da not_active IP Right Cessation
- 1978-09-04 NO NO783017A patent/NO151861C/no unknown
- 1978-09-06 NZ NZ188361A patent/NZ188361A/xx unknown
- 1978-09-06 PH PH21575A patent/PH15920A/en unknown
- 1978-09-06 IL IL7855521A patent/IL55521A0/xx not_active IP Right Cessation
- 1978-09-08 GR GR57185A patent/GR65703B/el unknown
- 1978-09-08 AU AU39668/78A patent/AU520178B2/en not_active Expired
- 1978-09-12 PT PT68544A patent/PT68544A/pt unknown
- 1978-09-13 CA CA311,197A patent/CA1129850A/en not_active Expired
- 1978-09-14 AR AR273708A patent/AR231544A1/es active
- 1978-09-15 IE IE1866/78A patent/IE47355B1/en not_active IP Right Cessation
- 1978-09-15 AT AT0669778A patent/AT370103B/de not_active IP Right Cessation
- 1978-09-15 FR FR7826533A patent/FR2403334A1/fr active Granted
- 1978-09-15 CH CH969078A patent/CH637954A5/de not_active IP Right Cessation
- 1978-09-16 PL PL1978225938A patent/PL121605B1/pl unknown
- 1978-09-16 PL PL1978217435A patent/PL118478B1/pl unknown
- 1978-09-16 PL PL1978209632A patent/PL112834B1/pl unknown
- 1978-09-18 IT IT51126/78A patent/IT1113279B/it active
- 1978-09-18 ZA ZA785291A patent/ZA785291B/xx unknown
- 1978-09-18 BE BE190553A patent/BE870562A/xx not_active IP Right Cessation
- 1978-09-18 YU YU2196/78A patent/YU41432B/xx unknown
- 1978-09-18 SU SU782665603A patent/SU895288A3/ru active
- 1978-09-18 HU HU78ME2204A patent/HU180868B/hu not_active IP Right Cessation
- 1978-09-19 GB GB8037685A patent/GB2061947B/en not_active Expired
- 1978-09-19 LU LU80262A patent/LU80262A1/xx unknown
- 1978-09-19 ES ES473492A patent/ES473492A1/es not_active Expired
- 1978-09-19 JP JP11420078A patent/JPS5463100A/ja active Granted
- 1978-09-19 GB GB7837284A patent/GB2004872B/en not_active Expired
- 1978-09-19 CY CY1283A patent/CY1283A/en unknown
- 1978-09-19 DE DE19782840786 patent/DE2840786A1/de active Granted
1979
- 1979-08-09 ES ES483287A patent/ES483287A1/es not_active Expired
- 1979-08-09 ES ES483283A patent/ES483283A1/es not_active Expired
- 1979-08-09 ES ES483285A patent/ES483285A1/es not_active Expired
- 1979-08-09 ES ES483286A patent/ES483286A1/es not_active Expired
- 1979-08-09 ES ES483288A patent/ES483288A1/es not_active Expired
- 1979-08-09 ES ES483284A patent/ES483284A1/es not_active Expired
- 1979-11-02 SU SU792834514A patent/SU915800A3/ru active
1985
- 1985-02-05 KE KE3501A patent/KE3501A/xx unknown
- 1985-02-07 SG SG95/85A patent/SG9585G/en unknown
- 1985-04-18 HK HK308/85A patent/HK30885A/xx not_active IP Right Cessation

Also Published As

Publication number	Publication date
ATA669778A (de)	1982-07-15
DK153843C (da)	1989-01-23
HU180868B (en)	1983-04-29
GR65703B (en)	1980-10-22
BE870562A (fr)	1979-03-19
FR2403334A1 (fr)	1979-04-13
NL191488B (nl)	1995-04-03
DK153843B (da)	1988-09-12
NZ188361A (en)	1982-06-29
ES483284A1 (es)	1980-09-01
FR2403334B1 (sv)	1982-11-19
ES483286A1 (es)	1980-04-16
SG9585G (en)	1985-08-08
PH15920A (en)	1983-04-22
ES483287A1 (es)	1980-04-16
JPS5639315B2 (sv)	1981-09-11
NL191488C (nl)	1995-08-04
ZA785291B (en)	1980-04-30
IE47355B1 (en)	1984-02-22
CH637954A5 (de)	1983-08-31
DK389978A (da)	1979-03-20
PL118478B1 (en)	1981-10-31
AU3966878A (en)	1980-03-13
GB2061947A (en)	1981-05-20
SU895288A3 (ru)	1981-12-30
PL209632A1 (pl)	1979-06-04
SU915800A3 (en)	1982-03-23
AR231544A1 (es)	1984-12-28
KE3501A (en)	1985-02-22
ES483288A1 (es)	1980-04-16
IE781866L (en)	1979-03-19
NO151861B (no)	1985-03-11
PL112834B1 (en)	1980-11-29
FI65618B (fi)	1984-02-29
HK30885A (en)	1985-04-26
IT7851126A0 (it)	1978-09-18
JPS5463100A (en)	1979-05-21
NO783017L (no)	1979-03-20
CA1129850A (en)	1982-08-17
AU520178B2 (en)	1982-01-21
GB2004872B (en)	1982-04-15
GB2061947B (en)	1982-08-04
YU41432B (en)	1987-06-30
DE2840786C2 (sv)	1987-05-21
GB2004872A (en)	1979-04-11
CY1283A (en)	1985-07-05
DE2840786A1 (de)	1979-03-22
NL7808847A (nl)	1979-03-21
IL55521A0 (en)	1978-12-17
IT1113279B (it)	1986-01-20
AT370103B (de)	1983-03-10
PL121605B1 (en)	1982-05-31
SE437520B (sv)	1985-03-04
ES483285A1 (es)	1980-09-01
FI65618C (fi)	1984-06-11
LU80262A1 (fr)	1979-06-01
ES483283A1 (es)	1980-04-16
YU219678A (en)	1983-02-28
NO151861C (no)	1985-06-19
ES473492A1 (es)	1980-07-16
FI782680A7 (fi)	1979-03-20
PT68544A (en)	1978-10-01

Legal Events

Date

Code

Title

Description

1995-01-31

NAL

Patent in force

Ref document number: 7809187-3

Format of ref document f/p: F

1998-12-07

NUG

Patent has lapsed