SE8300945L - Mellanprodukter for framstellning av 4-substituerade imidazo (1,2-a)kinoxaliner - Google Patents

Mellanprodukter for framstellning av 4-substituerade imidazo (1,2-a)kinoxaliner

Info

Publication number: SE8300945L
Authority: SE; Sweden
Prior art keywords: kinoxalines; intermediates; preparation; substituted imidazo; nitrogen
Prior art date: 1977-01-07

Application number

SE8300945A

Other languages

English (en)

Other versions

SE460477B (sv

SE8300945D0 (sv

Inventor

Jr P L Warner

Jr E J Luber

Original Assignee

Bristol Myers Co

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1977-01-07

Filing date

1983-02-21

Publication date

1983-02-21

1983-02-21 Application filed by Bristol Myers Co filed Critical Bristol Myers Co

1983-02-21 Publication of SE8300945D0 publication Critical patent/SE8300945D0/sv

1983-02-21 Publication of SE8300945L publication Critical patent/SE8300945L/sv

1989-10-16 Publication of SE460477B publication Critical patent/SE460477B/sv

Links

239000000543 intermediate Substances 0.000 title 1
IJGRMHOSHXDMSA-UHFFFAOYSA-N nitrogen Substances N#N IJGRMHOSHXDMSA-UHFFFAOYSA-N 0.000 abstract 3
125000001931 aliphatic group Chemical group 0.000 abstract 2
RAXXELZNTBOGNW-UHFFFAOYSA-N imidazole Natural products C1=CNC=N1 RAXXELZNTBOGNW-UHFFFAOYSA-N 0.000 abstract 2
229910052757 nitrogen Inorganic materials 0.000 abstract 2
125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 abstract 2
OKTJSMMVPCPJKN-UHFFFAOYSA-N Carbon Chemical compound [C] OKTJSMMVPCPJKN-UHFFFAOYSA-N 0.000 abstract 1
229910052799 carbon Inorganic materials 0.000 abstract 1
-1 cycloaliphatic Chemical group 0.000 abstract 1
229910052739 hydrogen Inorganic materials 0.000 abstract 1
239000001257 hydrogen Substances 0.000 abstract 1
125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 1
150000002460 imidazoles Chemical class 0.000 abstract 1
QJGQUHMNIGDVPM-UHFFFAOYSA-N nitrogen group Chemical group [N] QJGQUHMNIGDVPM-UHFFFAOYSA-N 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/06—Immunosuppressants, e.g. drugs for graft rejection

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Life Sciences & Earth Sciences (AREA)
General Health & Medical Sciences (AREA)
Immunology (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Veterinary Medicine (AREA)
Pharmacology & Pharmacy (AREA)
Public Health (AREA)
Animal Behavior & Ethology (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Transplantation (AREA)
Communicable Diseases (AREA)
Oncology (AREA)
Pain & Pain Management (AREA)
Rheumatology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)
Plural Heterocyclic Compounds (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)

SE8300945A 1977-01-07 1983-02-21 1-(2-acylaminofenyl)imidazoler till anvaendning sommellanprodukter SE460477B (sv)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
US75764077A	1977-01-07	1977-01-07

Publications (3)

Publication Number	Publication Date
SE8300945D0 SE8300945D0 (sv)	1983-02-21
SE8300945L true SE8300945L (sv)	1983-02-21
SE460477B SE460477B (sv)	1989-10-16

Family

ID=25048641

Family Applications (2)

Application Number	Title	Priority Date	Filing Date
SE7800138A SE436359B (sv)	1977-01-07	1978-01-05	Analogiforfarande for framstellning av 4-substituerade imidazo/1,2-a/kinoxaliner
SE8300945A SE460477B (sv)	1977-01-07	1983-02-21	1-(2-acylaminofenyl)imidazoler till anvaendning sommellanprodukter

Family Applications Before (1)

Application Number	Title	Priority Date	Filing Date
SE7800138A SE436359B (sv)	1977-01-07	1978-01-05	Analogiforfarande for framstellning av 4-substituerade imidazo/1,2-a/kinoxaliner

Country Status (19)

Country	Link
US (1)	US4160097A (sv)
JP (2)	JPS5387398A (sv)
AU (1)	AU521807B2 (sv)
BE (1)	BE862608A (sv)
CA (1)	CA1149385A (sv)
CH (2)	CH636102A5 (sv)
CS (1)	CS200232B2 (sv)
DE (2)	DE2858766C2 (sv)
DK (1)	DK157024C (sv)
FI (1)	FI64374C (sv)
FR (1)	FR2376858A1 (sv)
GB (2)	GB1579498A (sv)
GR (1)	GR73168B (sv)
IE (1)	IE46191B1 (sv)
LU (1)	LU78813A1 (sv)
NL (1)	NL7800114A (sv)
SE (2)	SE436359B (sv)
YU (1)	YU44663B (sv)
ZA (1)	ZA7827B (sv)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
SE439308B (sv) *	1978-08-02	1985-06-10	Roussel Uclaf	Imidazo(1,2-a)kinoxaliner och farmaceutiska kompositioner derav
JPS5569567A (en) *	1978-11-21	1980-05-26	Eisai Co Ltd	Novel imidazole compound, and antidepressant containing the same
IT1209431B (it) *	1980-11-28	1989-07-16	Angeli Inst Spa	Imidazolilfenil amidine, processi per la loro preparazione e loro impiego farmaceutico, ed intermedi di preparazione.
DE3830054A1 (de) *	1988-09-03	1990-03-15	Boehringer Mannheim Gmbh	Phenylamide - verfahren zu ihrer herstellung sowie diese verbindungen enthaltende arzneimittel
JPH0349309U (sv) *	1989-09-21	1991-05-14
US6235740B1 (en)	1997-08-25	2001-05-22	Bristol-Myers Squibb Co.	Imidazoquinoxaline protein tyrosine kinase inhibitors
US6635626B1 (en)	1997-08-25	2003-10-21	Bristol-Myers Squibb Co.	Imidazoquinoxaline protein tyrosine kinase inhibitors
CN1285834A (zh)	1997-11-11	2001-02-28	小野药品工业株式会社	稠合吡嗪化合物
ATE430149T1 (de) *	1998-03-04	2009-05-15	Bristol Myers Squibb Co	Heterocyclen substituierte imidazopyrazine als protein- tyrosin-kinase-inhibitoren
AU2002211827B2 (en)	2000-10-03	2006-12-14	Bristol-Myers Squibb Company	Amino-substituted tetracyclic compounds useful as anti-inflammatory agents and pharmaceutical compositions comprising same
US6869956B2 (en) *	2000-10-03	2005-03-22	Bristol-Myers Squibb Company	Methods of treating inflammatory and immune diseases using inhibitors of IκB kinase (IKK)
MXPA03006817A (es) *	2001-02-01	2003-11-13	Bristol Myers Squibb Co	Metodo de tratamiento de enfermedades inflamatorias e inmunes usando inhibidores de la ikb cinasa (ikk).
EP2066642A1 (en) *	2006-09-25	2009-06-10	Arete Therapeutics, INC.	Soluble epoxide hydrolase inhibitors

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US3541109A (en) *	1968-06-25	1970-11-17	Du Pont	1-substituted imidazoles useful in acth reserve assay
US4011236A (en) *	1968-09-09	1977-03-08	Merck & Co., Inc.	N-(benzimidazol-2-yl)arylcarboxamides as ultraviolet (uv) light absorbers
GB1347493A (en) *	1971-02-11	1974-02-27	Aspro Nicholas Ltd	Benzazine derivatives
US3994893A (en) *	1975-11-03	1976-11-30	E. R. Squibb & Sons, Inc.	4-Amino derivatives of pyrozolo[1,5-a]quinoxaline-3-carboxylic acid and esters

1977
- 1977-12-08 US US05/858,515 patent/US4160097A/en not_active Expired - Lifetime
- 1977-12-23 GR GR55051A patent/GR73168B/el unknown
- 1977-12-28 CA CA000293972A patent/CA1149385A/en not_active Expired
- 1977-12-28 JP JP15758177A patent/JPS5387398A/ja active Granted
1978
- 1978-01-03 BE BE184085A patent/BE862608A/xx not_active IP Right Cessation
- 1978-01-04 FI FI780023A patent/FI64374C/fi not_active IP Right Cessation
- 1978-01-04 DK DK004278A patent/DK157024C/da not_active IP Right Cessation
- 1978-01-04 NL NL7800114A patent/NL7800114A/xx not_active Application Discontinuation
- 1978-01-04 ZA ZA00780027A patent/ZA7827B/xx unknown
- 1978-01-05 DE DE2858766A patent/DE2858766C2/de not_active Expired - Fee Related
- 1978-01-05 DE DE19782800480 patent/DE2800480A1/de active Granted
- 1978-01-05 LU LU78813A patent/LU78813A1/xx unknown
- 1978-01-05 SE SE7800138A patent/SE436359B/sv not_active IP Right Cessation
- 1978-01-06 IE IE37/78A patent/IE46191B1/en unknown
- 1978-01-06 YU YU21/78A patent/YU44663B/xx unknown
- 1978-01-06 GB GB492/78A patent/GB1579498A/en not_active Expired
- 1978-01-06 GB GB13335/79A patent/GB1579499A/en not_active Expired
- 1978-01-06 FR FR7800308A patent/FR2376858A1/fr active Granted
- 1978-01-06 CH CH15278A patent/CH636102A5/fr not_active IP Right Cessation
- 1978-01-09 CS CS78169A patent/CS200232B2/cs unknown
- 1978-01-11 AU AU32331/78A patent/AU521807B2/en not_active Expired
1983
- 1983-01-18 CH CH27483A patent/CH640229A5/fr not_active IP Right Cessation
- 1983-02-21 SE SE8300945A patent/SE460477B/sv not_active IP Right Cessation
1986
- 1986-01-17 JP JP61006590A patent/JPS61171470A/ja active Granted

Also Published As

Publication number	Publication date
FI64374C (fi)	1983-11-10
SE460477B (sv)	1989-10-16
SE8300945D0 (sv)	1983-02-21
JPS6259110B2 (sv)	1987-12-09
DE2858766C2 (sv)	1990-04-05
NL7800114A (nl)	1978-07-11
SE436359B (sv)	1984-12-03
FI64374B (fi)	1983-07-29
FR2376858B1 (sv)	1980-10-24
JPS5387398A (en)	1978-08-01
ZA7827B (en)	1979-01-31
CA1149385A (en)	1983-07-05
DK157024C (da)	1990-04-02
SE7800138L (sv)	1978-07-08
DK4278A (da)	1978-07-08
IE46191B1 (en)	1983-03-23
FR2376858A1 (fr)	1978-08-04
DE2800480C2 (sv)	1990-04-12
YU44663B (en)	1990-12-31
GR73168B (sv)	1984-02-14
BE862608A (fr)	1978-07-03
YU2178A (en)	1990-04-30
IE780037L (en)	1978-07-07
CH636102A5 (fr)	1983-05-13
AU3233178A (en)	1979-07-19
JPH0130825B2 (sv)	1989-06-22
US4160097A (en)	1979-07-03
DE2800480A1 (de)	1978-07-13
LU78813A1 (fr)	1978-09-18
FI780023A7 (fi)	1978-07-08
GB1579499A (en)	1980-11-19
CS200232B2 (en)	1980-08-29
AU521807B2 (en)	1982-04-29
DK157024B (da)	1989-10-30
JPS61171470A (ja)	1986-08-02
GB1579498A (en)	1980-11-19
CH640229A5 (fr)	1983-12-30

Legal Events

Date

Code

Title

Description

1995-01-31

NUG

Patent has lapsed

Ref document number: 8300945-6

Effective date: 19920806

Format of ref document f/p: F

Publication	Publication Date	Title
SE8300945L (sv)	1983-02-21	Mellanprodukter for framstellning av 4-substituerade imidazo (1,2-a)kinoxaliner
FI852974L (fi)	1986-02-04	Nya n-hydroxylgruppen skyddande grupper och framstaellningsfoerfarande foer 3-acylamino-1-hydroxi-2-azetidinoner.
FI833918A0 (fi)	1983-10-26	-karboliner, foerfarande foer deras framstaellning och dessa innehaollande farmaceutiska preparat
DE3678797D1 (de)	1991-05-23	Neue 3-oxadiazol- und 3-carbonsaeure-beta-carbolinderivate, ihre herstellung und ihre verwendung als arzneimittel.
SE8002293L (sv)	1980-09-27	Nya antisekretoriska foreningar och deras anvendningsomrade
SE7909916L (sv)	1980-06-02	Beta,gamma-dihydropolyprenylalkoholer och farmaceutiska kompositioner innehallande desamma
SE7910072L (sv)	1980-06-08	Pyrrolo- eller pyrido(2,1-c)(1,4)tiaziner eller -tiazepiner
ZA816259B (en)	1983-04-27	2-(1,4-benzodioxan-2-ylalkyl)imidazoles useful as antidepressants
AU588065B2 (en)	1989-09-07	Substituted diazaoxaspirodecanes, preparation thereof and use thereof as stabilizers for polymers
ES545009A0 (es)	1986-07-16	Procedimiento de preparacion de nuevas fenil-naftiridinas.
SE8306740D0 (sv)	1983-12-06	2-thiacephems and (5r) penems derivatives
DE3264928D1 (en)	1985-08-29	Process for producing brominated 1,3-dioxolen-2-ones
ES8307236A1 (es)	1983-02-01	Un procedimiento para la preparacion de ranitidina.
SE8803765D0 (sv)	1988-10-21	Nya isopolypeptider samt foerfarande foer framstaellning av desamma
FI831521A0 (fi)	1983-05-03	Nytt foerfarande foer framstaellning av derivat av cyklopropankarboxylsyra och nya mellanprodukter
DK146389C (da)	1984-03-05	Analogifremgangsmaade til fremstilling af imidazo(1,2-a)imidazolforbindelser eller syreadditionssalte deraf
FI821583L (fi)	1982-11-08	Nya 1-pyrrolintiolaktimetrar och foerfarande foer deras framstaellning
ATE15184T1 (de)	1985-09-15	Fluorphenoxybenzylester, ihre herstellung und ihre verwendung als schaedlingsbekaempfungsmittel.
DK452984A (da)	1985-03-23	Fremgangsmaade til fremstilling af quinolin-4-oner
ES8301991A1 (es)	1982-12-16	Procedimiento para la preparacion de 7-(2,6-dibromo-4-metil-fenil)-2,3-dihidro-imidazo 1,2-a, imidazoles.
IE812607L (en)	1982-05-10	Heterobicyclic compounds
DK452684A (da)	1985-03-23	Fremgangsmaade til fremstilling af quinolin-4-oner
ES8205774A1 (es)	1982-08-16	Procedimiento para la obtencion de 2(1h)-piridinonas
BR7906840A (pt)	1980-06-24	Processo de obtencao de isocianatos alfa beta di halogeno alquilicos
ES8603861A1 (es)	1986-01-01	Un procedimiento para preparar derivados sustituidos de 1,3 -dioxano