SE8306882L - 7-karboximetoxifenylacetamido-3-cefem-derivat, forfaranden for framstellning derav och antibakteriella beredningar innehallande dem - Google Patents
7-karboximetoxifenylacetamido-3-cefem-derivat, forfaranden for framstellning derav och antibakteriella beredningar innehallande demInfo
- Publication number
- SE8306882L SE8306882L SE8306882A SE8306882A SE8306882L SE 8306882 L SE8306882 L SE 8306882L SE 8306882 A SE8306882 A SE 8306882A SE 8306882 A SE8306882 A SE 8306882A SE 8306882 L SE8306882 L SE 8306882L
- Authority
- SE
- Sweden
- Prior art keywords
- substituted
- carboximetoxifenylacetamido
- procedures
- preparing
- preparations containing
- Prior art date
Links
- 230000000844 anti-bacterial effect Effects 0.000 title abstract 2
- 238000000034 method Methods 0.000 title 1
- 238000002360 preparation method Methods 0.000 title 1
- 125000004423 acyloxy group Chemical group 0.000 abstract 2
- 239000001257 hydrogen Substances 0.000 abstract 2
- 229910052739 hydrogen Inorganic materials 0.000 abstract 2
- JUJWROOIHBZHMG-UHFFFAOYSA-O pyridinium Chemical class C1=CC=[NH+]C=C1 JUJWROOIHBZHMG-UHFFFAOYSA-O 0.000 abstract 2
- 150000003839 salts Chemical class 0.000 abstract 2
- 125000004178 (C1-C4) alkyl group Chemical group 0.000 abstract 1
- GHUZIVNTUZTXLL-LDZOIKDWSA-N 2-[[(6R)-8-oxo-4-[(2-phenylacetyl)amino]-5-thia-1-azabicyclo[4.2.0]oct-2-en-7-yl]oxy]acetic acid Chemical class C(=O)(O)COC1[C@@H]2N(C=CC(S2)NC(CC2=CC=CC=C2)=O)C1=O GHUZIVNTUZTXLL-LDZOIKDWSA-N 0.000 abstract 1
- 241000894006 Bacteria Species 0.000 abstract 1
- UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 abstract 1
- 125000005194 alkoxycarbonyloxy group Chemical group 0.000 abstract 1
- 125000003178 carboxy group Chemical group [H]OC(*)=O 0.000 abstract 1
- 150000001782 cephems Chemical class 0.000 abstract 1
- 125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 1
- 125000002887 hydroxy group Chemical group [H]O* 0.000 abstract 1
- 125000000956 methoxy group Chemical group [H]C([H])([H])O* 0.000 abstract 1
- QJGQUHMNIGDVPM-UHFFFAOYSA-N nitrogen group Chemical group [N] QJGQUHMNIGDVPM-UHFFFAOYSA-N 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
- C07D501/14—Compounds having a nitrogen atom directly attached in position 7
- C07D501/16—Compounds having a nitrogen atom directly attached in position 7 with a double bond between positions 2 and 3
- C07D501/20—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids
- C07D501/24—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids with hydrocarbon radicals, substituted by hetero atoms or hetero rings, attached in position 3
- C07D501/26—Methylene radicals, substituted by oxygen atoms; Lactones thereof with the 2-carboxyl group
- C07D501/34—Methylene radicals, substituted by oxygen atoms; Lactones thereof with the 2-carboxyl group with the 7-amino radical acylated by carboxylic acids containing hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
- C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D311/04—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring
- C07D311/22—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 4
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
- C07D501/14—Compounds having a nitrogen atom directly attached in position 7
- C07D501/16—Compounds having a nitrogen atom directly attached in position 7 with a double bond between positions 2 and 3
- C07D501/20—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids
- C07D501/24—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids with hydrocarbon radicals, substituted by hetero atoms or hetero rings, attached in position 3
- C07D501/36—Methylene radicals, substituted by sulfur atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
- C07D501/14—Compounds having a nitrogen atom directly attached in position 7
- C07D501/16—Compounds having a nitrogen atom directly attached in position 7 with a double bond between positions 2 and 3
- C07D501/20—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids
- C07D501/24—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids with hydrocarbon radicals, substituted by hetero atoms or hetero rings, attached in position 3
- C07D501/38—Methylene radicals, substituted by nitrogen atoms; Lactams thereof with the 2-carboxyl group; Methylene radicals substituted by nitrogen-containing hetero rings attached by the ring nitrogen atom; Quaternary compounds thereof
- C07D501/46—Methylene radicals, substituted by nitrogen atoms; Lactams thereof with the 2-carboxyl group; Methylene radicals substituted by nitrogen-containing hetero rings attached by the ring nitrogen atom; Quaternary compounds thereof with the 7-amino radical acylated by carboxylic acids containing hetero rings
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Cephalosporin Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP21772682A JPS59108791A (ja) | 1982-12-14 | 1982-12-14 | ７−カルボキシメトキシフエニルアセトアミド−３−セフエム誘導体、その製造方法およびそれからなる抗菌剤 |
| JP3601783A JPS59161389A (ja) | 1983-03-07 | 1983-03-07 | ７−カルボキシメトキシフエニルアセトアミドセフエム誘導体，その製造法およびそれからなる抗菌剤 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| SE8306882D0 SE8306882D0 (sv) | 1983-12-13 |
| SE8306882L true SE8306882L (sv) | 1984-06-15 |
Family
ID=26375029
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| SE8306882A SE8306882L (sv) | 1982-12-14 | 1983-12-13 | 7-karboximetoxifenylacetamido-3-cefem-derivat, forfaranden for framstellning derav och antibakteriella beredningar innehallande dem |
Country Status (16)
| Country | Link |
|---|---|
| US (1) | US4546176A (da) |
| KR (1) | KR840007012A (da) |
| AT (1) | ATA435283A (da) |
| AU (1) | AU2082783A (da) |
| BE (1) | BE898442A (da) |
| CH (1) | CH656131A5 (da) |
| DE (1) | DE3345093A1 (da) |
| DK (1) | DK572183A (da) |
| ES (2) | ES528003A0 (da) |
| FR (1) | FR2569195B1 (da) |
| GB (1) | GB2132613B (da) |
| IT (1) | IT1169969B (da) |
| NL (1) | NL8304272A (da) |
| PH (1) | PH20168A (da) |
| SE (1) | SE8306882L (da) |
| YU (1) | YU237283A (da) |
Families Citing this family (16)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5232918A (en) * | 1987-07-23 | 1993-08-03 | Imperial Chemical Industries Plc | Cephalosporin derivatives |
| US5273973A (en) * | 1988-10-24 | 1993-12-28 | Norwich Eaton Pharmaceuticals, Inc. | Antimicrobial quinolonyl esters |
| US5180719A (en) * | 1988-10-24 | 1993-01-19 | Norwich Eaton Pharmaceuticals, Inc. | Antimicrobial quinolonyl lactam esters |
| US5328908A (en) * | 1988-10-24 | 1994-07-12 | Procter & Gamble Pharmaceuticals, Inc. | Antimicrobial quinolone thioureas |
| CA2001203C (en) * | 1988-10-24 | 2001-02-13 | Thomas P. Demuth, Jr. | Novel antimicrobial dithiocarbamoyl quinolones |
| EP0997466A1 (en) * | 1988-10-24 | 2000-05-03 | PROCTER & GAMBLE PHARMACEUTICALS, INC. | Novel antimicrobial lactam-quinolones |
| US5491139A (en) * | 1988-10-24 | 1996-02-13 | The Procter & Gamble Company | Antimicrobial quinolonyl lactams |
| DK0525057T3 (da) * | 1990-04-18 | 2000-07-31 | Procter & Gamble Pharma | Antimikrobielle quinolonyllactamer |
| US5244892A (en) * | 1990-10-16 | 1993-09-14 | Kyorin Pharmaceutical Co., Ltd. | Cephem compounds, and antibacterial agents |
| EP0775145A1 (en) * | 1994-08-02 | 1997-05-28 | The Procter & Gamble Company | Process for making quinolonyl lactam antimicrobials and novel intermediate compounds |
| EP0775114B1 (en) * | 1994-08-02 | 2000-03-22 | The Procter & Gamble Company | Process for making antimicrobial compounds |
| TW200420573A (en) * | 2002-09-26 | 2004-10-16 | Rib X Pharmaceuticals Inc | Bifunctional heterocyclic compounds and methods of making and using same |
| CN1780846A (zh) * | 2003-03-05 | 2006-05-31 | Rib－X医药品有限公司 | 双官能杂环化合物及其制备和使用方法 |
| WO2005042554A1 (en) * | 2003-10-30 | 2005-05-12 | Rib-X Pharmaceuticals, Inc. | Bifunctional macrolide heterocyclic compounds and methods of making and using the same |
| US20070270357A1 (en) * | 2003-11-18 | 2007-11-22 | Farmer Jay J | Bifunctional Macrolide Heterocyclic Compounds and Methods of Making and Using the Same |
| US8202843B2 (en) | 2004-02-27 | 2012-06-19 | Rib-X Pharmaceuticals, Inc. | Macrocyclic compounds and methods of making and using the same |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AR208171A1 (es) * | 1972-09-29 | 1976-12-09 | Ciba Geigy Ag | Procedimiento para la obtencion de nuevos derivados del acido cef-3-em-4-carboxilico |
| US4338439A (en) * | 1976-08-26 | 1982-07-06 | Eli Lilly And Company | 7-[2-[(Substituted benzoyl]amino]acetamido]cephalosporins |
| DK548380A (da) * | 1980-03-04 | 1981-09-05 | Eisai Co Ltd | 7alfa-methoxycephalsporinderivater og fremgangsmaade til fremstilling deraf |
| US4468394A (en) * | 1981-04-02 | 1984-08-28 | Eisai Co., Ltd. | Cephalosporin compounds |
-
1983
- 1983-10-20 US US06/544,406 patent/US4546176A/en not_active Expired - Fee Related
- 1983-10-31 AU AU20827/83A patent/AU2082783A/en not_active Abandoned
- 1983-11-04 GB GB08329554A patent/GB2132613B/en not_active Expired
- 1983-11-23 PH PH29873A patent/PH20168A/en unknown
- 1983-12-05 YU YU02372/83A patent/YU237283A/xx unknown
- 1983-12-12 FR FR8319876A patent/FR2569195B1/fr not_active Expired
- 1983-12-12 IT IT24122/83A patent/IT1169969B/it active
- 1983-12-12 NL NL8304272A patent/NL8304272A/nl not_active Application Discontinuation
- 1983-12-13 SE SE8306882A patent/SE8306882L/xx not_active Application Discontinuation
- 1983-12-13 CH CH6649/83A patent/CH656131A5/de not_active IP Right Cessation
- 1983-12-13 DK DK572183A patent/DK572183A/da not_active Application Discontinuation
- 1983-12-13 DE DE19833345093 patent/DE3345093A1/de not_active Withdrawn
- 1983-12-13 BE BE0/212036A patent/BE898442A/fr not_active IP Right Cessation
- 1983-12-13 ES ES528003A patent/ES528003A0/es active Granted
- 1983-12-14 KR KR1019830005939A patent/KR840007012A/ko not_active Withdrawn
- 1983-12-14 AT AT0435283A patent/ATA435283A/de not_active Application Discontinuation
-
1984
- 1984-07-13 ES ES534297A patent/ES534297A0/es active Granted
Also Published As
| Publication number | Publication date |
|---|---|
| CH656131A5 (de) | 1986-06-13 |
| GB8329554D0 (en) | 1983-12-07 |
| YU237283A (en) | 1986-04-30 |
| FR2569195A1 (fr) | 1986-02-21 |
| GB2132613B (en) | 1986-05-08 |
| DE3345093A1 (de) | 1984-06-14 |
| ES8505691A1 (es) | 1985-06-01 |
| ATA435283A (de) | 1986-12-15 |
| BE898442A (fr) | 1984-06-13 |
| PH20168A (en) | 1986-10-09 |
| US4546176A (en) | 1985-10-08 |
| AU2082783A (en) | 1984-06-21 |
| DK572183D0 (da) | 1983-12-13 |
| FR2569195B1 (fr) | 1987-01-09 |
| KR840007012A (ko) | 1984-12-04 |
| IT1169969B (it) | 1987-06-03 |
| ES534297A0 (es) | 1985-06-01 |
| NL8304272A (nl) | 1984-07-02 |
| ES8506025A1 (es) | 1985-06-16 |
| GB2132613A (en) | 1984-07-11 |
| IT8324122A0 (it) | 1983-12-12 |
| SE8306882D0 (sv) | 1983-12-13 |
| DK572183A (da) | 1984-06-27 |
| ES528003A0 (es) | 1985-06-16 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| SE8306882L (sv) | 7-karboximetoxifenylacetamido-3-cefem-derivat, forfaranden for framstellning derav och antibakteriella beredningar innehallande dem | |
| JPS5746986A (en) | Pyrido(1,2,3-de)(1,4)benzoxazine derivative | |
| SE8600193D0 (sv) | Nya cefalosporiner | |
| ES8601220A1 (es) | Procedimiento de preparacion de nuevas sales de derivados organofosforados | |
| PT83423B (en) | Process for preparation of new quinoline derivatives | |
| ES8609343A1 (es) | Un metodo para preparar un derivado de cefem | |
| ES8202019A1 (es) | Un procedimiento para la preparacion de un compuesto de ce- falosporina | |
| SE8301929L (sv) | Nya karbapenemderivat, forfarande for framstellning derav och nya mellanprodukter for anvendning vid dessa forfaranden | |
| HUT73172A (en) | 3`-aziridino-anthracycline derivatives, pharmaceutical compns. contg. the said compds, process to prepare them and their use | |
| FI940011A0 (fi) | Mono- ja bis-alkyyliaminoantrasykliinit | |
| DE3170503D1 (en) | 3-0-demethyl derivatives of istamycin b series compounds and their preparation | |
| IE43346L (en) | Cephalosporin derivatives. | |
| DK206888A (da) | Thiadiazolylacetamidcephemderivat | |
| IE820238L (en) | Carbapenem derivatives | |
| GB1081635A (en) | Novel amines and a process for the preparation thereof | |
| ES2014041A6 (es) | Un procedimiento para preparar un derivado de amina. | |
| HU9302260D0 (en) | Tetrahydro-naphtaline derivatives and methods for producing these compounds and for preparing pharmaceutical preparatives containing them | |
| FR2244514A1 (en) | 1,2-Dihydroquinoline derivs - useful as anti-inflammatories | |
| GB2009731A (en) | Pyrido [3,2,1-jk] carbazol derivative | |
| ES454469A1 (es) | Un procedimiento de produccion de derivados de 7-(4-carboxi-butiramido)-7-metoxicefalosporina. | |
| ES8201587A1 (es) | Procedimiento de producir compuestos cefalosporinicos anti- microbianos | |
| GB2010835A (en) | I-Thiocyanato-8-substituted naphthalene derivatives | |
| JPS56123989A (en) | 7- n acylamino-alpha-arylacetamide -3- 1-substituted tetrazole- 5-ylthiomethyl cephalosporins | |
| ES8305773A1 (es) | Procedimiento para la obtencion de compuestos de aminohidroxifenilo. |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| NAV | Patent application has lapsed |
Ref document number: 8306882-5 Effective date: 19870416 Format of ref document f/p: F |