SE8601799L - (-)-1beta-etyl-1alfa-hydroximetyl-1,2,3,4,6,7,12,12balfa-iktahydroindolo/2,3-a/-kinolizin, forfarande for dess framstellning och farmaceutiska beredningar innehallande densamma - Google Patents

(-)-1beta-etyl-1alfa-hydroximetyl-1,2,3,4,6,7,12,12balfa-iktahydroindolo/2,3-a/-kinolizin, forfarande for dess framstellning och farmaceutiska beredningar innehallande densamma

Info

Publication number: SE8601799L
Authority: SE; Sweden
Prior art keywords: preparation; ethyl; formula; kinolizine; ictahydroindolo
Prior art date: 1985-04-19

Application number

SE8601799A

Other languages

English (en)

Other versions

SE460196B (sv

SE8601799D0 (sv

Inventor

C Szantay

L Szabo

G Kalaus

Z Szombathelyi

E Karpati

B Kiss

K Csomor

I Laszlovszky

E Lapis

L Szporny

L Forgacs

C Kuthi

A Gere

Original Assignee

Richter Gedeon Vegyeszet

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1985-04-19

Filing date

1986-04-18

Publication date

1986-10-20

1986-04-18 Application filed by Richter Gedeon Vegyeszet filed Critical Richter Gedeon Vegyeszet

1986-04-18 Publication of SE8601799D0 publication Critical patent/SE8601799D0/sv

1986-10-20 Publication of SE8601799L publication Critical patent/SE8601799L/sv

1989-09-18 Publication of SE460196B publication Critical patent/SE460196B/sv

Links

238000000034 method Methods 0.000 title abstract 2
150000001875 compounds Chemical class 0.000 abstract 3
150000003839 salts Chemical class 0.000 abstract 3
239000002253 acid Substances 0.000 abstract 2
239000004480 active ingredient Substances 0.000 abstract 1
230000015572 biosynthetic process Effects 0.000 abstract 1
230000000694 effects Effects 0.000 abstract 1
230000007062 hydrolysis Effects 0.000 abstract 1
238000006460 hydrolysis reaction Methods 0.000 abstract 1
230000002093 peripheral effect Effects 0.000 abstract 1
239000008194 pharmaceutical composition Substances 0.000 abstract 1
230000000304 vasodilatating effect Effects 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/12—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains three hetero rings
- C07D471/14—Ortho-condensed systems
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/08—Vasodilators for multiple indications

Landscapes

Organic Chemistry (AREA)
Chemical & Material Sciences (AREA)
Health & Medical Sciences (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Cardiology (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Medicinal Chemistry (AREA)
Life Sciences & Earth Sciences (AREA)
Pharmacology & Pharmacy (AREA)
Heart & Thoracic Surgery (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)
Quinoline Compounds (AREA)

SE8601799A 1985-04-19 1986-04-18 (-)-1beta-etyl-1alfa-hydroximetyl-1,2,3,4,6,7,12,12balfa-oktahydroindolo/2,3-a/kinolizin, foerfarande foer dess framstaellning och farmaceutiska beredningar innehaallande densamma SE460196B (sv)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
HU851519A HU194221B (en)	1985-04-19	1985-04-19	Process for preparing novel octahydro-indolo/2,3-a/quinoline derivative and pharmaceutical comprising this compound

Publications (3)

Publication Number	Publication Date
SE8601799D0 SE8601799D0 (sv)	1986-04-18
SE8601799L true SE8601799L (sv)	1986-10-20
SE460196B SE460196B (sv)	1989-09-18

Family

ID=10954847

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
SE8601799A SE460196B (sv)	1985-04-19	1986-04-18	(-)-1beta-etyl-1alfa-hydroximetyl-1,2,3,4,6,7,12,12balfa-oktahydroindolo/2,3-a/kinolizin, foerfarande foer dess framstaellning och farmaceutiska beredningar innehaallande densamma

Country Status (35)

Country	Link
US (1)	US4806545A (sv)
JP (1)	JPH072637B2 (sv)
CN (1)	CN1023560C (sv)
AR (1)	AR240699A1 (sv)
AT (1)	AT390954B (sv)
AU (1)	AU591896B2 (sv)
BE (1)	BE904588A (sv)
BG (1)	BG60433B2 (sv)
CA (1)	CA1299574C (sv)
CH (1)	CH668262A5 (sv)
CS (1)	CS274276B2 (sv)
DD (1)	DD244556A5 (sv)
DE (1)	DE3613180C2 (sv)
DK (1)	DK159780C (sv)
EG (1)	EG18059A (sv)
ES (1)	ES8706152A1 (sv)
FI (1)	FI83870C (sv)
FR (1)	FR2580649B1 (sv)
GB (1)	GB2174701B (sv)
GR (1)	GR861027B (sv)
HU (1)	HU194221B (sv)
IE (1)	IE59199B1 (sv)
IL (1)	IL78538A (sv)
IN (1)	IN162810B (sv)
IT (1)	IT1204306B (sv)
LU (1)	LU86397A1 (sv)
NL (1)	NL8600976A (sv)
NO (1)	NO167143C (sv)
NZ (1)	NZ215879A (sv)
PH (1)	PH25316A (sv)
PT (1)	PT82424B (sv)
SE (1)	SE460196B (sv)
SU (1)	SU1438612A3 (sv)
YU (1)	YU44286B (sv)
ZA (1)	ZA862941B (sv)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
HU191454B (en) *	1984-10-05	1987-02-27	Richter Gedeon Vegyeszeti Gyar Rt.,Hu	Process for producing amides of oktahydro-indolo/2,3-a/quinolyzin-1-yl-alkanecarboxylic acids and pharmaceutically acceptable acid additional salts thereof
HU195214B (en) *	1985-04-19	1988-04-28	Richter Gedeon Vegyeszet	Process for producing 12b-substituted-1-(hydroxymethyl)-octahydro-indolo /2,3-a/ quinolizine derivatives and pharmaceutical preparations comprising these compounds
HU194220B (en) *	1985-04-19	1988-01-28	Richter Gedeon Vegyeszet	Process for production of derivatives of 1,12 b disubstituated-octahydro-indolo /2,3-a/ quinolisine and medical compounds containing thereof
HU207070B (en) *	1990-10-31	1993-03-01	Richter Gedeon Vegyeszet	Process for producing 1beta-ethyl-1alpha-hydroxymethyl-1,2,3,4,6,712,12balpha-octahydroindolo(2,3-a) quinolizine
DE19821039A1 (de) *	1998-05-11	1999-11-18	Bayer Ag	Verfahren zur Herstellung von (S,S)-Benzyl-2,8-diazabicyclo[4.3.0]nonan
DE60316672T2 (de) *	2002-04-03	2008-07-17	Orion Corp.	Polycyclische verbindungen als potente alpha2-adrenoceptor antagonisten
AU2003235931A1 (en) *	2002-05-13	2003-11-11	Takata Seiyaku Co., Ltd.	Vintoperol-containing medicinal composition for transdermal administration

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
HU170495B (sv) *	1974-05-07	1977-06-28
GB1499546A (en) *	1974-05-07	1978-02-01	Richter Gedeon Vegyeszet	Indolo-quinolizidine derivatives and a process for the preparation thereof
HU195214B (en) *	1985-04-19	1988-04-28	Richter Gedeon Vegyeszet	Process for producing 12b-substituted-1-(hydroxymethyl)-octahydro-indolo /2,3-a/ quinolizine derivatives and pharmaceutical preparations comprising these compounds
HU194220B (en) *	1985-04-19	1988-01-28	Richter Gedeon Vegyeszet	Process for production of derivatives of 1,12 b disubstituated-octahydro-indolo /2,3-a/ quinolisine and medical compounds containing thereof

1985
- 1985-04-19 HU HU851519A patent/HU194221B/hu not_active IP Right Cessation
1986
- 1986-04-11 PH PH33639A patent/PH25316A/en unknown
- 1986-04-14 BE BE1/011476A patent/BE904588A/fr not_active IP Right Cessation
- 1986-04-14 US US06/851,327 patent/US4806545A/en not_active Expired - Fee Related
- 1986-04-16 CH CH1514/86A patent/CH668262A5/de not_active IP Right Cessation
- 1986-04-17 NL NL8600976A patent/NL8600976A/nl not_active Application Discontinuation
- 1986-04-17 EG EG215/86A patent/EG18059A/xx active
- 1986-04-17 YU YU624/86A patent/YU44286B/xx unknown
- 1986-04-18 IT IT20136/86A patent/IT1204306B/it active
- 1986-04-18 PT PT82424A patent/PT82424B/pt not_active IP Right Cessation
- 1986-04-18 SE SE8601799A patent/SE460196B/sv not_active IP Right Cessation
- 1986-04-18 IN IN292/MAS/86A patent/IN162810B/en unknown
- 1986-04-18 DK DK179786A patent/DK159780C/da active
- 1986-04-18 GB GB08609533A patent/GB2174701B/en not_active Expired
- 1986-04-18 CS CS286386A patent/CS274276B2/cs unknown
- 1986-04-18 JP JP61088398A patent/JPH072637B2/ja not_active Expired - Lifetime
- 1986-04-18 NZ NZ215879A patent/NZ215879A/xx unknown
- 1986-04-18 FR FR868605610A patent/FR2580649B1/fr not_active Expired - Lifetime
- 1986-04-18 SU SU864027292A patent/SU1438612A3/ru active
- 1986-04-18 ES ES554143A patent/ES8706152A1/es not_active Expired
- 1986-04-18 IL IL78538A patent/IL78538A/xx not_active IP Right Cessation
- 1986-04-18 AT AT0102986A patent/AT390954B/de not_active IP Right Cessation
- 1986-04-18 FI FI861641A patent/FI83870C/sv not_active IP Right Cessation
- 1986-04-18 ZA ZA862941A patent/ZA862941B/xx unknown
- 1986-04-18 GR GR861027A patent/GR861027B/el unknown
- 1986-04-18 CA CA000507011A patent/CA1299574C/en not_active Expired - Lifetime
- 1986-04-18 NO NO861539A patent/NO167143C/no unknown
- 1986-04-18 IE IE103386A patent/IE59199B1/en not_active IP Right Cessation
- 1986-04-18 AR AR30369386A patent/AR240699A1/es active
- 1986-04-18 DE DE3613180A patent/DE3613180C2/de not_active Expired - Fee Related
- 1986-04-18 LU LU86397A patent/LU86397A1/de unknown
- 1986-04-18 AU AU56383/86A patent/AU591896B2/en not_active Ceased
- 1986-04-18 DD DD86289372A patent/DD244556A5/de not_active IP Right Cessation
- 1986-04-19 CN CN86102479A patent/CN1023560C/zh not_active Expired - Lifetime
1993
- 1993-12-10 BG BG098290A patent/BG60433B2/bg unknown

Also Published As

Publication number	Publication date
PT82424A (en)	1986-05-01
HUT40433A (en)	1986-12-28
NL8600976A (nl)	1986-11-17
DK159780B (da)	1990-12-03
NZ215879A (en)	1989-04-26
DE3613180C2 (de)	1995-10-19
GB2174701A (en)	1986-11-12
FR2580649B1 (fr)	1991-03-29
ES554143A0 (es)	1987-06-01
CS274276B2 (en)	1991-04-11
PT82424B (pt)	1988-03-03
CS286386A2 (en)	1990-09-12
GR861027B (en)	1986-08-12
ZA862941B (en)	1986-12-30
DK179786D0 (da)	1986-04-18
NO167143C (no)	1991-10-09
AU591896B2 (en)	1989-12-21
YU44286B (en)	1990-04-30
CA1299574C (en)	1992-04-28
SE460196B (sv)	1989-09-18
BE904588A (fr)	1986-10-14
IE861033L (en)	1986-10-19
IT1204306B (it)	1989-03-01
NO167143B (no)	1991-07-01
BG60433B2 (bg)	1995-03-31
IL78538A0 (en)	1986-08-31
FI861641A0 (fi)	1986-04-18
FR2580649A1 (fr)	1986-10-24
DK179786A (da)	1986-10-20
DE3613180A1 (de)	1986-10-23
GB8609533D0 (en)	1986-05-21
NO861539L (no)	1986-10-20
AU5638386A (en)	1986-10-23
ES8706152A1 (es)	1987-06-01
IT8620136A0 (it)	1986-04-18
CN1023560C (zh)	1994-01-19
AR240699A1 (es)	1990-09-28
PH25316A (en)	1991-04-30
SE8601799D0 (sv)	1986-04-18
CN86102479A (zh)	1986-10-22
DD244556A5 (de)	1987-04-08
JPH072637B2 (ja)	1995-01-18
HU194221B (en)	1988-01-28
AT390954B (de)	1990-07-25
LU86397A1 (sv)	1986-09-02
YU62486A (en)	1988-06-30
EG18059A (en)	1991-06-30
JPS61249986A (ja)	1986-11-07
FI83870B (fi)	1991-05-31
FI83870C (sv)	1991-09-10
IL78538A (en)	1989-10-31
IN162810B (sv)	1988-07-09
GB2174701B (en)	1989-02-15
IE59199B1 (en)	1994-01-26
CH668262A5 (de)	1988-12-15
ATA102986A (de)	1990-01-15
DK159780C (da)	1991-04-22
US4806545A (en)	1989-02-21
SU1438612A3 (ru)	1988-11-15
FI861641L (fi)	1986-10-20

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