SG11202004502SA - Anti-alpha-synuclein antibodies - Google Patents

Anti-alpha-synuclein antibodies

Info

Publication number: SG11202004502SA
Authority: SG; Singapore
Prior art keywords: alpha; synuclein antibodies; synuclein; antibodies
Prior art date: 2017-12-15

Application number

SG11202004502SA

Other languages

English (en)

Inventor

Ralph Adams

Patrick Downey

Terence Seward Baker

Kerry Louise Tyson

Lichtervelde Lorenzo De

Daniel John Lightwood

David James Mcmillan

Original Assignee

UCB Biopharma SRL

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2017-12-15

Filing date

2018-12-13

Publication date

2020-06-29

2018-12-13 Application filed by UCB Biopharma SRL filed Critical UCB Biopharma SRL

2020-06-29 Publication of SG11202004502SA publication Critical patent/SG11202004502SA/en

Links

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A61P25/16—Anti-Parkinson drugs
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
- G01N33/6893—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids related to diseases not provided for elsewhere
- G01N33/6896—Neurological disorders, e.g. Alzheimer's disease
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
- C07K2317/24—Immunoglobulins specific features characterized by taxonomic origin containing regions, domains or residues from different species, e.g. chimeric, humanized or veneered
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/30—Immunoglobulins specific features characterized by aspects of specificity or valency
- C07K2317/33—Crossreactivity, e.g. for species or epitope, or lack of said crossreactivity
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/30—Immunoglobulins specific features characterized by aspects of specificity or valency
- C07K2317/34—Identification of a linear epitope shorter than 20 amino acid residues or of a conformational epitope defined by amino acid residues
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
- C07K2317/51—Complete heavy chain or Fd fragment, i.e. VH + CH1
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
- C07K2317/515—Complete light chain, i.e. VL + CL
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
- C07K2317/55—Fab or Fab'
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
- C07K2317/56—Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
- C07K2317/56—Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
- C07K2317/565—Complementarity determining region [CDR]
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
- C07K2317/56—Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
- C07K2317/567—Framework region [FR]
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
- C07K2317/76—Antagonist effect on antigen, e.g. neutralization or inhibition of binding
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/90—Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin
- C07K2317/92—Affinity (KD), association rate (Ka), dissociation rate (Kd) or EC50 value
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/90—Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin
- C07K2317/94—Stability, e.g. half-life, pH, temperature or enzyme-resistance
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2800/00—Detection or diagnosis of diseases
- G01N2800/28—Neurological disorders
- G01N2800/2835—Movement disorders, e.g. Parkinson, Huntington, Tourette

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Engineering & Computer Science (AREA)
Organic Chemistry (AREA)
Biomedical Technology (AREA)
General Health & Medical Sciences (AREA)
Immunology (AREA)
Molecular Biology (AREA)
Medicinal Chemistry (AREA)
Biochemistry (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Neurology (AREA)
Neurosurgery (AREA)
Genetics & Genomics (AREA)
Biophysics (AREA)
Hematology (AREA)
Urology & Nephrology (AREA)
Bioinformatics & Cheminformatics (AREA)
Food Science & Technology (AREA)
Animal Behavior & Ethology (AREA)
General Physics & Mathematics (AREA)
Pathology (AREA)
Physics & Mathematics (AREA)
Psychology (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Biotechnology (AREA)
Pharmacology & Pharmacy (AREA)
Analytical Chemistry (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Microbiology (AREA)
Cell Biology (AREA)
Peptides Or Proteins (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Preparation Of Compounds By Using Micro-Organisms (AREA)
Micro-Organisms Or Cultivation Processes Thereof (AREA)

SG11202004502SA 2017-12-15 2018-12-13 Anti-alpha-synuclein antibodies SG11202004502SA (en)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
GBGB1720975.0A GB201720975D0 (en)	2017-12-15	2017-12-15	Anti-alpha synuclein antibodies
PCT/EP2018/084697 WO2019115674A1 (fr)	2017-12-15	2018-12-13	Anticorps anti-alpha-synucléine

Publications (1)

Publication Number	Publication Date
SG11202004502SA true SG11202004502SA (en)	2020-06-29

Family

ID=61009086

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
SG11202004502SA SG11202004502SA (en)	2017-12-15	2018-12-13	Anti-alpha-synuclein antibodies

Country Status (26)

Country	Link
US (2)	US11261242B2 (fr)
EP (1)	EP3724224A1 (fr)
JP (2)	JP7292279B2 (fr)
KR (1)	KR102789446B1 (fr)
CN (1)	CN111479826B (fr)
AR (1)	AR115192A1 (fr)
AU (1)	AU2018382530B2 (fr)
BR (1)	BR112020010504A2 (fr)
CA (1)	CA3083199A1 (fr)
CL (1)	CL2020001605A1 (fr)
EA (1)	EA202091478A1 (fr)
EC (1)	ECSP20039623A (fr)
GB (1)	GB201720975D0 (fr)
IL (1)	IL275187B2 (fr)
MA (1)	MA51135A (fr)
MX (2)	MX2020005691A (fr)
MY (1)	MY205948A (fr)
PE (1)	PE20201061A1 (fr)
PH (1)	PH12020551007A1 (fr)
SG (1)	SG11202004502SA (fr)
TN (2)	TN2021000169A1 (fr)
TW (2)	TWI801469B (fr)
UA (1)	UA126295C2 (fr)
UY (1)	UY38010A (fr)
WO (1)	WO2019115674A1 (fr)
ZA (2)	ZA202003542B (fr)

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EA201991720A1 (ru)	2017-02-17	2020-01-20	Бристол-Маерс Сквибб Компани	Антитела к альфа-синуклеину и их применения
GB201720975D0 (en) *	2017-12-15	2018-01-31	Ucb Biopharma Sprl	Anti-alpha synuclein antibodies
GB201720970D0 (en)	2017-12-15	2018-01-31	Ucb Biopharma Sprl	Antibodies
WO2020079113A1 (fr) *	2018-10-19	2020-04-23	Janssen Vaccines & Prevention B.V.	Anticorps anti-synucléine
WO2021055881A1 (fr) *	2019-09-20	2021-03-25	Denali Therapeutics Inc.	Anticorps anti-alpha-synucléine et leurs procédés d'utilisation
US20230025256A1 (en) *	2019-12-04	2023-01-26	Simon Friedman	Protein blocking assembly and methods of making and using
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GB201720970D0 (en)	2017-12-15	2018-01-31	Ucb Biopharma Sprl	Antibodies

2017
- 2017-12-15 GB GBGB1720975.0A patent/GB201720975D0/en not_active Ceased
2018
- 2018-12-13 CA CA3083199A patent/CA3083199A1/fr active Pending
- 2018-12-13 IL IL275187A patent/IL275187B2/en unknown
- 2018-12-13 MY MYPI2020002453A patent/MY205948A/en unknown
- 2018-12-13 EA EA202091478A patent/EA202091478A1/ru unknown
- 2018-12-13 TN TNP/2021/000169A patent/TN2021000169A1/en unknown
- 2018-12-13 JP JP2020532596A patent/JP7292279B2/ja active Active
- 2018-12-13 CN CN201880080854.1A patent/CN111479826B/zh active Active
- 2018-12-13 MA MA051135A patent/MA51135A/fr unknown
- 2018-12-13 UA UAA202002941A patent/UA126295C2/uk unknown
- 2018-12-13 PE PE2020000707A patent/PE20201061A1/es unknown
- 2018-12-13 EP EP18829767.5A patent/EP3724224A1/fr active Pending
- 2018-12-13 WO PCT/EP2018/084697 patent/WO2019115674A1/fr not_active Ceased
- 2018-12-13 MX MX2020005691A patent/MX2020005691A/es unknown
- 2018-12-13 US US16/771,993 patent/US11261242B2/en active Active
- 2018-12-13 BR BR112020010504-0A patent/BR112020010504A2/pt unknown
- 2018-12-13 TN TNP/2020/000069A patent/TN2020000069A1/en unknown
- 2018-12-13 SG SG11202004502SA patent/SG11202004502SA/en unknown
- 2018-12-13 KR KR1020207019487A patent/KR102789446B1/ko active Active
- 2018-12-13 AU AU2018382530A patent/AU2018382530B2/en active Active
- 2018-12-14 AR ARP180103657A patent/AR115192A1/es unknown
- 2018-12-14 TW TW107145283A patent/TWI801469B/zh active
- 2018-12-14 TW TW112114559A patent/TW202332692A/zh unknown
- 2018-12-14 UY UY0001038010A patent/UY38010A/es not_active Application Discontinuation
2020
- 2020-06-12 ZA ZA2020/03542A patent/ZA202003542B/en unknown
- 2020-06-14 PH PH12020551007A patent/PH12020551007A1/en unknown
- 2020-06-15 CL CL2020001605A patent/CL2020001605A1/es unknown
- 2020-07-13 MX MX2024013356A patent/MX2024013356A/es unknown
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2023
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Also Published As

Publication number	Publication date
EP3724224A1 (fr)	2020-10-21
GB201720975D0 (en)	2018-01-31
ZA202103456B (en)	2023-01-25
PH12020551007A1 (en)	2021-08-16
KR20200099160A (ko)	2020-08-21
KR102789446B1 (ko)	2025-04-01
CA3083199A1 (fr)	2019-06-20
AU2018382530B2 (en)	2025-04-17
US20220220192A1 (en)	2022-07-14
US20210107971A1 (en)	2021-04-15
CL2020001605A1 (es)	2020-08-28
RU2020123274A (ru)	2022-01-17
JP7627300B2 (ja)	2025-02-05
TN2021000169A1 (en)	2023-04-04
CN111479826B (zh)	2024-10-29
MX2024013356A (es)	2024-12-06
EA202091478A1 (ru)	2020-09-04
RU2020123274A3 (fr)	2022-01-17
TWI801469B (zh)	2023-05-11
PE20201061A1 (es)	2020-10-16
TN2020000069A1 (en)	2022-01-06
TW201930354A (zh)	2019-08-01
IL275187B2 (en)	2026-05-01
MX2020005691A (es)	2020-08-20
UA126295C2 (uk)	2022-09-14
JP2023127585A (ja)	2023-09-13
CN111479826A (zh)	2020-07-31
JP7292279B2 (ja)	2023-06-16
US11261242B2 (en)	2022-03-01
TW202332692A (zh)	2023-08-16
JP2021509012A (ja)	2021-03-18
WO2019115674A1 (fr)	2019-06-20
US12545720B2 (en)	2026-02-10
IL275187A (en)	2020-07-30
AR115192A1 (es)	2020-12-09
IL275187B1 (en)	2026-01-01
UY38010A (es)	2019-07-31
MA51135A (fr)	2021-03-24
MY205948A (en)	2024-11-21
ECSP20039623A (es)	2020-08-31
ZA202003542B (en)	2022-12-21
AU2018382530A1 (en)	2020-06-18
BR112020010504A2 (pt)	2020-11-24

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