SG49788A1 - Radiolabeled compounds for thrombus imaging - Google Patents

Radiolabeled compounds for thrombus imaging

Info

Publication number
SG49788A1
SG49788A1 SG1996006000A SG1996006000A SG49788A1 SG 49788 A1 SG49788 A1 SG 49788A1 SG 1996006000 A SG1996006000 A SG 1996006000A SG 1996006000 A SG1996006000 A SG 1996006000A SG 49788 A1 SG49788 A1 SG 49788A1
Authority
SG
Singapore
Prior art keywords
pct
methods
compounds
sec
date
Prior art date
Application number
SG1996006000A
Other languages
English (en)
Inventor
Richard T Dean
John Lister-James
Edgar R Civitello
Bride William Mc
Original Assignee
Diatide Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Diatide Inc filed Critical Diatide Inc
Publication of SG49788A1 publication Critical patent/SG49788A1/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
    • A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
    • A61K51/04—Organic compounds
    • A61K51/08—Peptides, e.g. proteins, carriers being peptides, polyamino acids, proteins
    • A61K51/088—Peptides, e.g. proteins, carriers being peptides, polyamino acids, proteins conjugates with carriers being peptides, polyamino acids or proteins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
    • A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
    • A61K51/04—Organic compounds
    • A61K51/08—Peptides, e.g. proteins, carriers being peptides, polyamino acids, proteins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
    • A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
    • A61K51/04—Organic compounds
    • A61K51/08—Peptides, e.g. proteins, carriers being peptides, polyamino acids, proteins
    • A61K51/082—Peptides, e.g. proteins, carriers being peptides, polyamino acids, proteins the peptide being a RGD-containing peptide
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2123/00—Preparations for testing in vivo

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Optics & Photonics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Physics & Mathematics (AREA)
  • Public Health (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Ultra Sonic Daignosis Equipment (AREA)
  • Surgical Instruments (AREA)
  • Measurement Of Radiation (AREA)
SG1996006000A 1993-04-08 1994-04-08 Radiolabeled compounds for thrombus imaging SG49788A1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US4482593A 1993-04-08 1993-04-08

Publications (1)

Publication Number Publication Date
SG49788A1 true SG49788A1 (en) 1998-06-15

Family

ID=21934541

Family Applications (1)

Application Number Title Priority Date Filing Date
SG1996006000A SG49788A1 (en) 1993-04-08 1994-04-08 Radiolabeled compounds for thrombus imaging

Country Status (13)

Country Link
US (1) US6056940A (fr)
EP (1) EP0693941B1 (fr)
JP (1) JP2954355B2 (fr)
AT (1) ATE220926T1 (fr)
AU (1) AU687080B2 (fr)
BR (1) BR1100946A (fr)
CA (2) CA2363780C (fr)
DE (1) DE69431052T2 (fr)
DK (1) DK0693941T3 (fr)
ES (1) ES2179076T3 (fr)
SG (1) SG49788A1 (fr)
WO (1) WO1994023758A1 (fr)
ZA (1) ZA942439B (fr)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5849261A (en) * 1991-02-08 1998-12-15 Diatide, Inc. Radiolabeled vasoactive intestinal peptides for diagnosis and therapy
US5443815A (en) * 1991-11-27 1995-08-22 Diatech, Inc. Technetium-99m labeled peptides for imaging
US6019958A (en) * 1991-02-08 2000-02-01 Diatide, Inc. Technetium-99m labeled peptides for imaging inflammation
US5645815A (en) * 1991-02-08 1997-07-08 Diatide, Inc. Radiolabled compounds for thrombus imaging
US5997844A (en) * 1991-02-08 1999-12-07 Diatide, Inc. Technetium-99m labeled peptides for imaging
US7238340B1 (en) * 1991-11-27 2007-07-03 Cis Bio International Monoamine, diamide, thiol-containing metal chelating agents
DE69230525T2 (de) * 1991-02-08 2000-06-21 Diatide, Inc. Technetium-99m markierte Polypeptide zur Bildformung
US5736122A (en) * 1991-02-08 1998-04-07 Diatide, Inc. Technetium-99m labeled peptides for thrombus imaging
US5830856A (en) * 1991-02-08 1998-11-03 Diatide, Inc. Radiolabeled compounds for thrombus imaging
US5965107A (en) * 1992-03-13 1999-10-12 Diatide, Inc. Technetium-99m labeled peptides for imaging
US5989519A (en) * 1992-03-13 1999-11-23 Diatide, Inc. Technetium-99m labeled peptides for imaging inflammation
US5508020A (en) * 1992-06-05 1996-04-16 Diatech, Inc. Technetium-99M labeled peptides for imaging
US5968476A (en) * 1992-05-21 1999-10-19 Diatide, Inc. Technetium-99m labeled peptides for thrombus imaging
CN1087955C (zh) * 1994-05-02 2002-07-24 迪亚太德公司 锝－99m标记的成像剂
US5753206A (en) 1995-06-07 1998-05-19 Immunomedics, Inc. Radiometal-binding analogues of luteinizing hormone releasing hormone
EP0975374B1 (fr) * 1996-07-12 2007-12-05 Immunomedics, Inc. Analogues de peptides liant des radiometaux
US5951981A (en) * 1996-12-02 1999-09-14 Diatide, Inc. Thrombolytic agents with antithrombotic activity
US5886142A (en) * 1997-05-20 1999-03-23 Thomas Jefferson University Radiolabeled thrombus imaging agents
DE10005631A1 (de) * 2000-02-09 2001-08-23 Max Planck Gesellschaft Arginin-Mimetika als Faktor X¶a¶-Inhibitoren
EP1608299B1 (fr) * 2003-03-26 2010-05-12 Cardiomind, Inc. Cathéter de distribution d'implants avec liens solubles par electrolyse

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Publication number Priority date Publication date Assignee Title
US4792525A (en) * 1982-08-04 1988-12-20 La Jolla Cancer Research Foundation Tetrapeptide
US4578079A (en) * 1982-08-04 1986-03-25 La Jolla Cancer Research Foundation Tetrapeptide
US5225181A (en) * 1985-06-07 1993-07-06 The Research Foundation Of State University Of New York Radiolabeled antiplatelet monoclonal antibody for imaging in-vivo thrombi
US4877868A (en) * 1986-03-12 1989-10-31 Neorx Corporation Radionuclide antibody coupling
WO1989002752A1 (fr) * 1987-09-25 1989-04-06 Genentech, Inc. Procede de diagnostic de caillots sanguins utilisant des proteines liant la fibrine
WO1989005150A1 (fr) * 1987-12-10 1989-06-15 La Jolla Cancer Research Foundation Peptides d'adhesion cellulaire a stabilisation conformationnelle
WO1989010759A1 (fr) * 1988-04-29 1989-11-16 Mallinckrodt, Inc. Agents chelateurs de diaminedithiol pour substances radiopharmaceutiques
US5196510A (en) * 1988-12-29 1993-03-23 Cytogen Corporation Molecular recognition units
US4986979A (en) * 1989-03-14 1991-01-22 Neorx Corporation Imaging tissue sites of inflammation
GB8914020D0 (en) * 1989-06-19 1989-08-09 Antisoma Ltd Synthetic peptides for use in thrombus detection
US5384309A (en) * 1989-07-17 1995-01-24 Genentech, Inc. Cyclized peptides and their use as platelet aggregation inhibitors
CA2021950A1 (fr) * 1989-07-28 1991-01-29 Ruth F. Nutt Antagonistes des recepteurs du fibrinogene
CA2021951A1 (fr) * 1989-07-28 1991-01-29 Ruth F. Nutt Antagonistes des recepteurs du fibrinogene
EP0410539A1 (fr) * 1989-07-28 1991-01-30 Merck & Co. Inc. Antagonistes des récepteurs fibrinogéniques
EP0410537A1 (fr) * 1989-07-28 1991-01-30 Merck & Co. Inc. Antagonistes pour le récepteur du fibrinogène
US5443816A (en) * 1990-08-08 1995-08-22 Rhomed Incorporated Peptide-metal ion pharmaceutical preparation and method
US4952562A (en) * 1989-09-29 1990-08-28 Rorer Pharmaceutical Corporation Anti-thrombotic peptides and pseudopeptides
NZ235564A (en) * 1989-10-13 1993-10-26 Merck & Co Inc Fibrinogen receptor antagonist and pharmaceutical compositions
NZ235563A (en) * 1989-10-13 1993-04-28 Merck & Co Inc Fibrinogen receptor antagonist and pharmaceutical composition
CA2027936C (fr) * 1989-10-23 2001-07-24 Smithkline Beecham Corporation Peptides cycliques anti-agregants
US5086069A (en) * 1990-02-05 1992-02-04 Rorer Pharmaceutical Corporation Anti-thrombotic peptide and pseudopeptide derivatives
IL97459A0 (en) * 1990-03-09 1992-06-21 Hybritech Inc Trifunctional antibody-like compounds as a combined diagnostic and therapeutic agent
DK0527798T3 (da) * 1990-04-06 1997-12-15 Jolla Cancer Res Found Fremgangsmåde og sammensætning til behandling af thrombose
US5105327A (en) * 1990-05-10 1992-04-14 Uses, Inc. Ac power conditioning circuit
IL99537A (en) * 1990-09-27 1995-11-27 Merck & Co Inc Fibrinogen receptor antagonists and pharmaceutical compositions containing them
US5965107A (en) * 1992-03-13 1999-10-12 Diatide, Inc. Technetium-99m labeled peptides for imaging
DE69230525T2 (de) * 1991-02-08 2000-06-21 Diatide, Inc. Technetium-99m markierte Polypeptide zur Bildformung
US5645815A (en) * 1991-02-08 1997-07-08 Diatide, Inc. Radiolabled compounds for thrombus imaging
EP0574545B1 (fr) * 1991-03-06 1994-11-30 G.D. Searle & Co. Derives d'amidines de phenyle efficaces en tant qu'inhibiteurs d'agregation des plaquettes
AU666853B2 (en) * 1991-04-05 1996-02-29 Genentech Inc. Platelet aggregation inhibitors having high specificity for GP IIbIIIa
US5321034A (en) * 1991-05-07 1994-06-14 Merck & Co., Inc. Fibrinogen receptor antagonists
US5220050A (en) * 1991-05-17 1993-06-15 G. D. Searle & Co. Peptide mimetic compounds useful as platelet aggregation inhibitors
US5693636A (en) * 1991-06-28 1997-12-02 Smithkline Beecham Corporation Bicyclic fibrinogen antagonists
US5250679A (en) * 1991-10-18 1993-10-05 Genentech, Inc. Nonpeptidyl platelet aggregation inhibitors having specificity for the GPIIb III.sub. receptor
US5508020A (en) * 1992-06-05 1996-04-16 Diatech, Inc. Technetium-99M labeled peptides for imaging
EP0641222B1 (fr) * 1992-05-21 2000-09-06 Diatide, Inc. PEPTIDES MARQUES AU TECHNETIUM-99m DESTINES A L'IMAGERIE DE THROMBUS
US5879657A (en) * 1993-03-30 1999-03-09 The Dupont Merck Pharmaceutical Company Radiolabeled platelet GPIIb/IIIa receptor antagonists as imaging agents for the diagnosis of thromboembolic disorders
US5744120A (en) * 1993-03-30 1998-04-28 The Dupont Merick Pharmaceutical Company Ternary radiopharmaceutical complexes

Also Published As

Publication number Publication date
ZA942439B (en) 1996-01-08
ATE220926T1 (de) 2002-08-15
AU687080B2 (en) 1998-02-19
CA2363780A1 (fr) 1994-10-27
AU7241394A (en) 1994-11-08
WO1994023758A1 (fr) 1994-10-27
EP0693941B1 (fr) 2002-07-24
BR1100946A (pt) 2000-08-08
EP0693941A1 (fr) 1996-01-31
CA2160120A1 (fr) 1994-10-27
DE69431052T2 (de) 2003-03-13
JPH08508999A (ja) 1996-09-24
CA2363780C (fr) 2003-01-07
DK0693941T3 (da) 2002-10-14
US6056940A (en) 2000-05-02
DE69431052D1 (de) 2002-08-29
JP2954355B2 (ja) 1999-09-27
ES2179076T3 (es) 2003-01-16

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