SI1358182T1 - Diazocine derivates and their use as tryptase inhibitors - Google Patents

Diazocine derivates and their use as tryptase inhibitors

Info

Publication number: SI1358182T1
Authority: SI; Slovenia
Prior art keywords: diazocine; derivates; tryptase inhibitors; inhibitors; tryptase
Prior art date: 2001-01-31

Application number

SI200230037T

Other languages

English (en)

Slovenian (sl)

Inventor

Ulfich

Baer

Martin

Stadlwieser

Wollin

Zech

Sommerhoff

Original Assignee

Altana Pharma Ag

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2001-01-31

Filing date

2002-01-26

Publication date

2005-02-28

2002-01-26 Application filed by Altana Pharma Ag filed Critical Altana Pharma Ag

2005-02-28 Publication of SI1358182T1 publication Critical patent/SI1358182T1/xx

Links

239000002750 tryptase inhibitor Substances 0.000 title abstract 2
YZTFIKANQHTFDZ-UHFFFAOYSA-N diazocine Chemical compound C1=CC=CN=NC=C1 YZTFIKANQHTFDZ-UHFFFAOYSA-N 0.000 title 1
150000001875 compounds Chemical class 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing three or more hetero rings
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/02—Stomatological preparations, e.g. drugs for caries, aphtae, periodontitis
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/02—Nasal agents, e.g. decongestants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/06—Antiasthmatics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/10—Drugs for disorders of the urinary system of the bladder
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/06—Antipsoriatics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
- A61P27/14—Decongestants or antiallergics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Landscapes

Health & Medical Sciences (AREA)
Organic Chemistry (AREA)
Chemical & Material Sciences (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Life Sciences & Earth Sciences (AREA)
General Health & Medical Sciences (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Animal Behavior & Ethology (AREA)
Veterinary Medicine (AREA)
Pharmacology & Pharmacy (AREA)
Public Health (AREA)
Chemical Kinetics & Catalysis (AREA)
Immunology (AREA)
Pulmonology (AREA)
Biomedical Technology (AREA)
Dermatology (AREA)
Neurosurgery (AREA)
Neurology (AREA)
Urology & Nephrology (AREA)
Rheumatology (AREA)
Heart & Thoracic Surgery (AREA)
Hospice & Palliative Care (AREA)
Ophthalmology & Optometry (AREA)
Cardiology (AREA)
Psychiatry (AREA)
Pain & Pain Management (AREA)
Vascular Medicine (AREA)
Orthopedic Medicine & Surgery (AREA)
Physical Education & Sports Medicine (AREA)
Transplantation (AREA)
Otolaryngology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Preparation Of Compounds By Using Micro-Organisms (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Polysaccharides And Polysaccharide Derivatives (AREA)
Macromolecular Compounds Obtained By Forming Nitrogen-Containing Linkages In General (AREA)
Plural Heterocyclic Compounds (AREA)

SI200230037T 2001-01-31 2002-01-26 Diazocine derivates and their use as tryptase inhibitors SI1358182T1 (en)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
EP01102098		2001-01-31
PCT/EP2002/000831 WO2002060895A1 (en)	2001-01-31	2002-01-26	Diazocine derivatives and their use as tryptase inhibitors

Publications (1)

Publication Number	Publication Date
SI1358182T1 true SI1358182T1 (en)	2005-02-28

Family

ID=8176347

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
SI200230037T SI1358182T1 (en)	2001-01-31	2002-01-26	Diazocine derivates and their use as tryptase inhibitors

Country Status (12)

Country	Link
US (1)	US6924305B2 (de)
EP (1)	EP1358182B1 (de)
JP (1)	JP2004517943A (de)
AT (1)	ATE273302T1 (de)
AU (1)	AU2002238522B8 (de)
CA (1)	CA2438594A1 (de)
DE (1)	DE60200935T2 (de)
DK (1)	DK1358182T3 (de)
ES (1)	ES2225758T3 (de)
PT (1)	PT1358182E (de)
SI (1)	SI1358182T1 (de)
WO (1)	WO2002060895A1 (de)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
CA2450659A1 (en)	2001-06-19	2002-12-27	Altana Pharma Ag	Tryptase inhibitors
WO2006044133A1 (en) *	2004-09-24	2006-04-27	Axys Pharmaceuticals, Inc.	Active ketone inhibitors of tryptase

Family Cites Families (14)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
AU2764495A (en)	1994-06-01	1995-12-21	Arris Pharmaceutical Corporation	Compositions and methods for treating mast-cell mediated conditions
PL183552B1 (pl)	1994-09-23	2002-06-28	Axys Pharmaceuticals	Nowe związki cykliczne i środek farmaceutyczny
EE9900036A (et) *	1996-07-30	1999-08-16	Arris Pharmaceutical Corporation	Uued ühendid ja kompositsioonid trüptaasi aktiivsusega seotud haiguste raviks
WO1999012918A1 (en)	1997-09-05	1999-03-18	Yoshitomi Pharmaceutical Industries, Ltd.	Tryptase inhibitor
AU1208999A (en)	1997-11-10	1999-05-31	Array Biopharma, Inc.	Compounds which inhibit tryptase activity
US6221914B1 (en)	1997-11-10	2001-04-24	Array Biopharma Inc.	Sulfonamide bridging compounds that inhibit tryptase activity
EP1060171A2 (de)	1998-02-06	2000-12-20	Max-Planck-Gesellschaft zur Förderung der Wissenschaften e.V.	Tryptase-inhibitoren
US6489327B1 (en)	1998-02-06	2002-12-03	Max-Planck-Gesellschaft Zur Fordrungder Wisenschaften, E.V.	Tryptase inhibitors
EP1115731A2 (de)	1998-09-04	2001-07-18	Byk Gulden Lomberg Chemische Fabrik GmbH	Neue pyranosen
DE19937721A1 (de)	1999-08-10	2001-02-15	Max Planck Gesellschaft	Neue Diketopiperazine
KR20020016942A (ko)	1999-08-10	2002-03-06	빅 굴덴 롬베르크 케미쉐 파브릭 게엠베하	디아조신-디온 유도체 및 이것의 트립타제 억제제로서 용도
AU778965B2 (en)	1999-09-14	2004-12-23	Altana Pharma Ag	Tryptase inhibitors
AU783217B2 (en)	1999-12-20	2005-10-06	Altana Pharma Ag	Tryptase inhibitors
CA2392127A1 (en)	1999-12-20	2001-06-28	Byk Gulden Lomberg Chemische Fabrik Gmbh	Tryptase inhibitors

2002
- 2002-01-26 ES ES02704674T patent/ES2225758T3/es not_active Expired - Lifetime
- 2002-01-26 SI SI200230037T patent/SI1358182T1/xx unknown
- 2002-01-26 CA CA002438594A patent/CA2438594A1/en not_active Abandoned
- 2002-01-26 US US10/466,906 patent/US6924305B2/en not_active Expired - Fee Related
- 2002-01-26 WO PCT/EP2002/000831 patent/WO2002060895A1/en not_active Ceased
- 2002-01-26 DK DK02704674T patent/DK1358182T3/da active
- 2002-01-26 AU AU2002238522A patent/AU2002238522B8/en not_active Ceased
- 2002-01-26 EP EP02704674A patent/EP1358182B1/de not_active Expired - Lifetime
- 2002-01-26 JP JP2002561044A patent/JP2004517943A/ja not_active Withdrawn
- 2002-01-26 DE DE60200935T patent/DE60200935T2/de not_active Expired - Fee Related
- 2002-01-26 PT PT02704674T patent/PT1358182E/pt unknown
- 2002-01-26 AT AT02704674T patent/ATE273302T1/de not_active IP Right Cessation

Also Published As

Publication number	Publication date
WO2002060895A1 (en)	2002-08-08
EP1358182B1 (de)	2004-08-11
AU2002238522A1 (en)	2002-08-12
DK1358182T3 (da)	2004-12-20
PT1358182E (pt)	2004-12-31
US6924305B2 (en)	2005-08-02
ATE273302T1 (de)	2004-08-15
US20040072762A1 (en)	2004-04-15
AU2002238522B8 (en)	2007-01-18
JP2004517943A (ja)	2004-06-17
AU2002238522B2 (en)	2006-12-21
DE60200935T2 (de)	2005-09-01
CA2438594A1 (en)	2002-08-08
ES2225758T3 (es)	2005-03-16
DE60200935D1 (de)	2004-09-16
EP1358182A1 (de)	2003-11-05

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DE60112974D1 (en)	2005-09-29	Carbolinderivate
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WO2004018431A3 (en)	2004-04-22	Novel phenanthridines
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TW200600499A (en)	2006-01-01	Novel amido-substituted hydroxy-6-phenylphenanthridines
AU2001264081A1 (en)	2001-12-24	Serine protease inhibitors
GB0018951D0 (en)	2000-09-20	Novel compounds
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DE60127131D1 (de)	2007-04-19	Tricyclische imidazopyridine
ATE287403T1 (de)	2005-02-15	6-phenylbenzonaphthyidine
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GB0027705D0 (en)	2000-12-27	Novel compounds
DE60011677D1 (en)	2004-07-22	Tryptase-inhibitoren
ATE268322T1 (de)	2004-06-15	Inhibitoren der tryptase
DE60216920D1 (en)	2007-02-01	Tryptase-inhibitoren
SI1358182T1 (en)	2005-02-28	Diazocine derivates and their use as tryptase inhibitors
DE60220504D1 (en)	2007-07-19	Tryptasehemmer
PL373989A1 (en)	2005-09-19	Novel benzonaphthyridines