ATE273302T1 - Diazocinderivate und deren verwendung als tryptase inhibitoren - Google Patents
Diazocinderivate und deren verwendung als tryptase inhibitorenInfo
- Publication number
- ATE273302T1 ATE273302T1 AT02704674T AT02704674T ATE273302T1 AT E273302 T1 ATE273302 T1 AT E273302T1 AT 02704674 T AT02704674 T AT 02704674T AT 02704674 T AT02704674 T AT 02704674T AT E273302 T1 ATE273302 T1 AT E273302T1
- Authority
- AT
- Austria
- Prior art keywords
- tryptase inhibitors
- diazocine
- derivatives
- diazocine derivatives
- inhibitors
- Prior art date
Links
- 239000002750 tryptase inhibitor Substances 0.000 title abstract 2
- YZTFIKANQHTFDZ-UHFFFAOYSA-N diazocine Chemical class C1=CC=CN=NC=C1 YZTFIKANQHTFDZ-UHFFFAOYSA-N 0.000 title 1
- 150000001875 compounds Chemical class 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing three or more hetero rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/02—Stomatological preparations, e.g. drugs for caries, aphtae, periodontitis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/02—Nasal agents, e.g. decongestants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/06—Antiasthmatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/10—Drugs for disorders of the urinary system of the bladder
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/06—Antipsoriatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
- A61P27/14—Decongestants or antiallergics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Immunology (AREA)
- Pulmonology (AREA)
- Dermatology (AREA)
- Biomedical Technology (AREA)
- Neurosurgery (AREA)
- Neurology (AREA)
- Urology & Nephrology (AREA)
- Rheumatology (AREA)
- Hospice & Palliative Care (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Ophthalmology & Optometry (AREA)
- Transplantation (AREA)
- Psychiatry (AREA)
- Pain & Pain Management (AREA)
- Heart & Thoracic Surgery (AREA)
- Cardiology (AREA)
- Otolaryngology (AREA)
- Vascular Medicine (AREA)
- Physical Education & Sports Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Plural Heterocyclic Compounds (AREA)
- Polysaccharides And Polysaccharide Derivatives (AREA)
- Macromolecular Compounds Obtained By Forming Nitrogen-Containing Linkages In General (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP01102098 | 2001-01-31 | ||
| PCT/EP2002/000831 WO2002060895A1 (en) | 2001-01-31 | 2002-01-26 | Diazocine derivatives and their use as tryptase inhibitors |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE273302T1 true ATE273302T1 (de) | 2004-08-15 |
Family
ID=8176347
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT02704674T ATE273302T1 (de) | 2001-01-31 | 2002-01-26 | Diazocinderivate und deren verwendung als tryptase inhibitoren |
Country Status (12)
| Country | Link |
|---|---|
| US (1) | US6924305B2 (de) |
| EP (1) | EP1358182B1 (de) |
| JP (1) | JP2004517943A (de) |
| AT (1) | ATE273302T1 (de) |
| AU (1) | AU2002238522B8 (de) |
| CA (1) | CA2438594A1 (de) |
| DE (1) | DE60200935T2 (de) |
| DK (1) | DK1358182T3 (de) |
| ES (1) | ES2225758T3 (de) |
| PT (1) | PT1358182E (de) |
| SI (1) | SI1358182T1 (de) |
| WO (1) | WO2002060895A1 (de) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ES2278928T3 (es) | 2001-06-19 | 2007-08-16 | Altana Pharma Ag | Inhibidores de triptasa. |
| WO2006044133A1 (en) * | 2004-09-24 | 2006-04-27 | Axys Pharmaceuticals, Inc. | Active ketone inhibitors of tryptase |
Family Cites Families (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO1995032945A1 (en) | 1994-06-01 | 1995-12-07 | Arris Pharmaceutical Corporation | Compositions and methods for treating mast-cell mediated conditions |
| KR970706267A (ko) * | 1994-09-23 | 1997-11-03 | 다니엘 에이치. 페트리 | 비만 세포 염증성 질환 치료용 조성물 및 방법(compositions and methods for treating mast-cell inflammatory condition) |
| AU733621B2 (en) * | 1996-07-30 | 2001-05-17 | Axys Pharmaceuticals, Inc. | Novel compounds and compositions for treating diseases associated with tryptase activity |
| AU8997498A (en) | 1997-09-05 | 1999-03-29 | Yoshitomi Pharmaceutical Industries, Ltd. | Tryptase inhibitor |
| US6221914B1 (en) | 1997-11-10 | 2001-04-24 | Array Biopharma Inc. | Sulfonamide bridging compounds that inhibit tryptase activity |
| EP1030844A1 (de) | 1997-11-10 | 2000-08-30 | Array Biopharma Inc. | Verbindungen, die die aktivität von tryptase hemmen |
| ES2233025T3 (es) | 1998-02-06 | 2005-06-01 | Max-Planck-Gesellschaft Zur Forderung Der Wissenschaften E.V. | Agente inhibidores de la triptasa. |
| EP1060171A2 (de) | 1998-02-06 | 2000-12-20 | Max-Planck-Gesellschaft zur Förderung der Wissenschaften e.V. | Tryptase-inhibitoren |
| WO2000014097A2 (de) | 1998-09-04 | 2000-03-16 | Byk Gulden Lomberg Chemische Fabrik Gmbh | Neue pyranosen |
| JP2003506442A (ja) | 1999-08-10 | 2003-02-18 | アルタナ ファルマ アクチエンゲゼルシャフト | 新規トリプターゼインヒビター |
| DE19937721A1 (de) | 1999-08-10 | 2001-02-15 | Max Planck Gesellschaft | Neue Diketopiperazine |
| JP2003509417A (ja) | 1999-09-14 | 2003-03-11 | アルタナ ファルマ アクチエンゲゼルシャフト | トリプターゼインヒビター |
| TR200402322T4 (tr) | 1999-12-20 | 2004-12-21 | Altana Pharma Ag | Triptaz inhibitörler |
| JP2003518087A (ja) | 1999-12-20 | 2003-06-03 | アルタナ ファルマ アクチエンゲゼルシャフト | トリプターゼインヒビター |
-
2002
- 2002-01-26 PT PT02704674T patent/PT1358182E/pt unknown
- 2002-01-26 US US10/466,906 patent/US6924305B2/en not_active Expired - Fee Related
- 2002-01-26 AT AT02704674T patent/ATE273302T1/de not_active IP Right Cessation
- 2002-01-26 EP EP02704674A patent/EP1358182B1/de not_active Expired - Lifetime
- 2002-01-26 DK DK02704674T patent/DK1358182T3/da active
- 2002-01-26 DE DE60200935T patent/DE60200935T2/de not_active Expired - Fee Related
- 2002-01-26 AU AU2002238522A patent/AU2002238522B8/en not_active Ceased
- 2002-01-26 JP JP2002561044A patent/JP2004517943A/ja not_active Withdrawn
- 2002-01-26 SI SI200230037T patent/SI1358182T1/xx unknown
- 2002-01-26 ES ES02704674T patent/ES2225758T3/es not_active Expired - Lifetime
- 2002-01-26 CA CA002438594A patent/CA2438594A1/en not_active Abandoned
- 2002-01-26 WO PCT/EP2002/000831 patent/WO2002060895A1/en not_active Ceased
Also Published As
| Publication number | Publication date |
|---|---|
| SI1358182T1 (en) | 2005-02-28 |
| AU2002238522B2 (en) | 2006-12-21 |
| EP1358182A1 (de) | 2003-11-05 |
| CA2438594A1 (en) | 2002-08-08 |
| US6924305B2 (en) | 2005-08-02 |
| US20040072762A1 (en) | 2004-04-15 |
| DE60200935T2 (de) | 2005-09-01 |
| AU2002238522B8 (en) | 2007-01-18 |
| PT1358182E (pt) | 2004-12-31 |
| DE60200935D1 (de) | 2004-09-16 |
| DK1358182T3 (da) | 2004-12-20 |
| EP1358182B1 (de) | 2004-08-11 |
| JP2004517943A (ja) | 2004-06-17 |
| WO2002060895A1 (en) | 2002-08-08 |
| ES2225758T3 (es) | 2005-03-16 |
| AU2002238522A1 (en) | 2002-08-12 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| UEP | Publication of translation of european patent specification |
Ref document number: 1358182 Country of ref document: EP |
|
| REN | Ceased due to non-payment of the annual fee |