SK123496A3 - A rapid microbiological test for the detection of antibacterial compounds - Google Patents

A rapid microbiological test for the detection of antibacterial compounds Download PDF

Info

Publication number: SK123496A3
Authority: SK; Slovakia
Prior art keywords: test; agar medium; microorganism; sample; added
Prior art date: 1995-02-01

Application number

SK1234-96A

Other languages

English (en)

Slovak (sk)

Inventor

Pieter C Langeveld

Robert Beukers

Michiel W C Bommele

Jacobus Stark

Original Assignee

Gist Brocades Bv

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1995-02-01

Filing date

1996-02-01

Publication date

1997-07-09

Family has litigation

First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=8219988&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=SK123496(A3) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.

1996-02-01 Application filed by Gist Brocades Bv filed Critical Gist Brocades Bv

1997-07-09 Publication of SK123496A3 publication Critical patent/SK123496A3/sk

Links

150000001875 compounds Chemical class 0.000 title claims abstract description 42
230000000844 anti-bacterial effect Effects 0.000 title claims abstract description 37
238000001514 detection method Methods 0.000 title claims description 8
238000012009 microbiological test Methods 0.000 title abstract description 12
238000012360 testing method Methods 0.000 claims abstract description 149
238000000034 method Methods 0.000 claims abstract description 31
241000193830 Bacillus <bacterium> Species 0.000 claims abstract description 16
239000007788 liquid Substances 0.000 claims abstract description 14
239000002824 redox indicator Substances 0.000 claims abstract description 12
241000193385 Geobacillus stearothermophilus Species 0.000 claims abstract description 10
239000002696 acid base indicator Substances 0.000 claims abstract description 9
241000194017 Streptococcus Species 0.000 claims abstract description 5
229920001817 Agar Polymers 0.000 claims description 74
239000008272 agar Substances 0.000 claims description 74
244000005700 microbiome Species 0.000 claims description 41
JGSARLDLIJGVTE-MBNYWOFBSA-N Penicillin G Chemical compound N([C@H]1[C@H]2SC([C@@H](N2C1=O)C(O)=O)(C)C)C(=O)CC1=CC=CC=C1 JGSARLDLIJGVTE-MBNYWOFBSA-N 0.000 claims description 39
229940056360 penicillin g Drugs 0.000 claims description 19
235000015097 nutrients Nutrition 0.000 claims description 18
238000004519 manufacturing process Methods 0.000 claims description 13
241000194020 Streptococcus thermophilus Species 0.000 claims description 9
230000001580 bacterial effect Effects 0.000 claims description 8
239000000126 substance Substances 0.000 claims description 6
239000007787 solid Substances 0.000 claims description 5
230000008859 change Effects 0.000 claims description 4
230000001332 colony forming effect Effects 0.000 claims description 3
235000013336 milk Nutrition 0.000 abstract description 22
239000008267 milk Substances 0.000 abstract description 22
210000004080 milk Anatomy 0.000 abstract description 22
210000002966 serum Anatomy 0.000 abstract description 6
210000002700 urine Anatomy 0.000 abstract description 6
235000011389 fruit/vegetable juice Nutrition 0.000 abstract description 5
235000013372 meat Nutrition 0.000 abstract description 5
238000003556 assay Methods 0.000 description 23
239000000523 sample Substances 0.000 description 21
230000035945 sensitivity Effects 0.000 description 16
XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 11
238000011534 incubation Methods 0.000 description 10
239000000872 buffer Substances 0.000 description 7
239000003242 anti bacterial agent Substances 0.000 description 6
235000020247 cow milk Nutrition 0.000 description 6
230000002906 microbiologic effect Effects 0.000 description 6
SEEPANYCNGTZFQ-UHFFFAOYSA-N sulfadiazine Chemical compound C1=CC(N)=CC=C1S(=O)(=O)NC1=NC=CC=N1 SEEPANYCNGTZFQ-UHFFFAOYSA-N 0.000 description 6
229960004306 sulfadiazine Drugs 0.000 description 6
WQZGKKKJIJFFOK-GASJEMHNSA-N Glucose Natural products OC[C@H]1OC(O)[C@H](O)[C@@H](O)[C@@H]1O WQZGKKKJIJFFOK-GASJEMHNSA-N 0.000 description 5
229940088710 antibiotic agent Drugs 0.000 description 5
FAPWRFPIFSIZLT-UHFFFAOYSA-M Sodium chloride Chemical compound [Na+].[Cl-] FAPWRFPIFSIZLT-UHFFFAOYSA-M 0.000 description 4
230000003115 biocidal effect Effects 0.000 description 4
229940041514 candida albicans extract Drugs 0.000 description 4
238000002425 crystallisation Methods 0.000 description 4
230000008025 crystallization Effects 0.000 description 4
239000012153 distilled water Substances 0.000 description 4
239000012138 yeast extract Substances 0.000 description 4
MUBZPKHOEPUJKR-UHFFFAOYSA-N Oxalic acid Chemical class OC(=O)C(O)=O MUBZPKHOEPUJKR-UHFFFAOYSA-N 0.000 description 3
XAGFODPZIPBFFR-UHFFFAOYSA-N aluminium Chemical compound [Al] XAGFODPZIPBFFR-UHFFFAOYSA-N 0.000 description 3
229910052782 aluminium Inorganic materials 0.000 description 3
230000000845 anti-microbial effect Effects 0.000 description 3
239000013068 control sample Substances 0.000 description 3
230000002596 correlated effect Effects 0.000 description 3
239000008121 dextrose Substances 0.000 description 3
230000000694 effects Effects 0.000 description 3
239000011888 foil Substances 0.000 description 3
238000002360 preparation method Methods 0.000 description 3
230000009467 reduction Effects 0.000 description 3
150000003467 sulfuric acid derivatives Chemical class 0.000 description 3
239000000725 suspension Substances 0.000 description 3
-1 1-10 Phenantrolin Chemical compound 0.000 description 2
IJGRMHOSHXDMSA-UHFFFAOYSA-N Atomic nitrogen Chemical compound N#N IJGRMHOSHXDMSA-UHFFFAOYSA-N 0.000 description 2
CURLTUGMZLYLDI-UHFFFAOYSA-N Carbon dioxide Chemical compound O=C=O CURLTUGMZLYLDI-UHFFFAOYSA-N 0.000 description 2
KRHYYFGTRYWZRS-UHFFFAOYSA-N Fluorane Chemical class F KRHYYFGTRYWZRS-UHFFFAOYSA-N 0.000 description 2
229930182555 Penicillin Natural products 0.000 description 2
239000001888 Peptone Substances 0.000 description 2
108010080698 Peptones Proteins 0.000 description 2
GSEJCLTVZPLZKY-UHFFFAOYSA-N Triethanolamine Chemical compound OCCN(CCO)CCO GSEJCLTVZPLZKY-UHFFFAOYSA-N 0.000 description 2
QIRDPEPUXNCOLD-UHFFFAOYSA-N [9-(diethylamino)benzo[a]phenoxazin-5-ylidene]azanium;sulfate Chemical compound [O-]S([O-])(=O)=O.C1=CC=C2C3=NC4=CC=C(N(CC)CC)C=C4OC3=CC(=[NH2+])C2=C1.C1=CC=C2C3=NC4=CC=C(N(CC)CC)C=C4OC3=CC(=[NH2+])C2=C1 QIRDPEPUXNCOLD-UHFFFAOYSA-N 0.000 description 2
WQZGKKKJIJFFOK-VFUOTHLCSA-N beta-D-glucose Chemical compound OC[C@H]1O[C@@H](O)[C@H](O)[C@@H](O)[C@@H]1O WQZGKKKJIJFFOK-VFUOTHLCSA-N 0.000 description 2
235000011089 carbon dioxide Nutrition 0.000 description 2
239000003795 chemical substances by application Substances 0.000 description 2
239000011248 coating agent Substances 0.000 description 2
238000000576 coating method Methods 0.000 description 2
XJRPTMORGOIMMI-UHFFFAOYSA-N ethyl 2-amino-4-(trifluoromethyl)-1,3-thiazole-5-carboxylate Chemical compound CCOC(=O)C=1SC(N)=NC=1C(F)(F)F XJRPTMORGOIMMI-UHFFFAOYSA-N 0.000 description 2
239000008103 glucose Substances 0.000 description 2
239000004615 ingredient Substances 0.000 description 2
CXKWCBBOMKCUKX-UHFFFAOYSA-M methylene blue Chemical compound [Cl-].C1=CC(N(C)C)=CC2=[S+]C3=CC(N(C)C)=CC=C3N=C21 CXKWCBBOMKCUKX-UHFFFAOYSA-M 0.000 description 2
229960000907 methylthioninium chloride Drugs 0.000 description 2
239000000203 mixture Substances 0.000 description 2
235000018343 nutrient deficiency Nutrition 0.000 description 2
235000016709 nutrition Nutrition 0.000 description 2
235000019319 peptone Nutrition 0.000 description 2
239000011780 sodium chloride Substances 0.000 description 2
238000003860 storage Methods 0.000 description 2
IEDVJHCEMCRBQM-UHFFFAOYSA-N trimethoprim Chemical compound COC1=C(OC)C(OC)=CC(CC=2C(=NC(N)=NC=2)N)=C1 IEDVJHCEMCRBQM-UHFFFAOYSA-N 0.000 description 2
229960001082 trimethoprim Drugs 0.000 description 2
235000012431 wafers Nutrition 0.000 description 2
LNOBZXNCABUBKK-UHFFFAOYSA-N 2,3,5-triphenyltetrazolium Chemical compound C1=CC=CC=C1C(N=[N+]1C=2C=CC=CC=2)=NN1C1=CC=CC=C1 LNOBZXNCABUBKK-UHFFFAOYSA-N 0.000 description 1
KZDCMKVLEYCGQX-UDPGNSCCSA-N 2-(diethylamino)ethyl 4-aminobenzoate;(2s,5r,6r)-3,3-dimethyl-7-oxo-6-[(2-phenylacetyl)amino]-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid;hydrate Chemical compound O.CCN(CC)CCOC(=O)C1=CC=C(N)C=C1.N([C@H]1[C@H]2SC([C@@H](N2C1=O)C(O)=O)(C)C)C(=O)CC1=CC=CC=C1 KZDCMKVLEYCGQX-UDPGNSCCSA-N 0.000 description 1
MKNQNPYGAQGARI-UHFFFAOYSA-N 4-(bromomethyl)phenol Chemical compound OC1=CC=C(CBr)C=C1 MKNQNPYGAQGARI-UHFFFAOYSA-N 0.000 description 1
KEEYRKYKLYARHO-UHFFFAOYSA-N 5-[(4,5-dimethoxy-2-methylphenyl)methyl]pyrimidine-2,4-diamine Chemical compound C1=C(OC)C(OC)=CC(C)=C1CC1=CN=C(N)N=C1N KEEYRKYKLYARHO-UHFFFAOYSA-N 0.000 description 1
GUBGYTABKSRVRQ-XLOQQCSPSA-N Alpha-Lactose Chemical compound O[C@@H]1[C@@H](O)[C@@H](O)[C@@H](CO)O[C@H]1O[C@@H]1[C@@H](CO)O[C@H](O)[C@H](O)[C@H]1O GUBGYTABKSRVRQ-XLOQQCSPSA-N 0.000 description 1
241000894006 Bacteria Species 0.000 description 1
OKTJSMMVPCPJKN-UHFFFAOYSA-N Carbon Chemical compound [C] OKTJSMMVPCPJKN-UHFFFAOYSA-N 0.000 description 1
108091006149 Electron carriers Proteins 0.000 description 1
235000000177 Indigofera tinctoria Nutrition 0.000 description 1
XXACTDWGHQXLGW-UHFFFAOYSA-M Janus Green B chloride Chemical compound [Cl-].C12=CC(N(CC)CC)=CC=C2N=C2C=CC(\N=N\C=3C=CC(=CC=3)N(C)C)=CC2=[N+]1C1=CC=CC=C1 XXACTDWGHQXLGW-UHFFFAOYSA-M 0.000 description 1
GUBGYTABKSRVRQ-QKKXKWKRSA-N Lactose Natural products OC[C@H]1O[C@@H](O[C@H]2[C@H](O)[C@@H](O)C(O)O[C@@H]2CO)[C@H](O)[C@@H](O)[C@H]1O GUBGYTABKSRVRQ-QKKXKWKRSA-N 0.000 description 1
BELBBZDIHDAJOR-UHFFFAOYSA-N Phenolsulfonephthalein Chemical compound C1=CC(O)=CC=C1C1(C=2C=CC(O)=CC=2)C2=CC=CC=C2S(=O)(=O)O1 BELBBZDIHDAJOR-UHFFFAOYSA-N 0.000 description 1
239000004098 Tetracycline Substances 0.000 description 1
IURGIPVDZKDLIX-UHFFFAOYSA-M [7-(diethylamino)phenoxazin-3-ylidene]-diethylazanium;chloride Chemical compound [Cl-].C1=CC(=[N+](CC)CC)C=C2OC3=CC(N(CC)CC)=CC=C3N=C21 IURGIPVDZKDLIX-UHFFFAOYSA-M 0.000 description 1
239000002253 acid Substances 0.000 description 1
CQPFMGBJSMSXLP-UHFFFAOYSA-M acid orange 7 Chemical compound [Na+].OC1=CC=C2C=CC=CC2=C1N=NC1=CC=C(S([O-])(=O)=O)C=C1 CQPFMGBJSMSXLP-UHFFFAOYSA-M 0.000 description 1
230000009471 action Effects 0.000 description 1
230000004075 alteration Effects 0.000 description 1
239000003708 ampul Substances 0.000 description 1
230000003432 anti-folate effect Effects 0.000 description 1
229940127074 antifolate Drugs 0.000 description 1
239000002246 antineoplastic agent Substances 0.000 description 1
230000008901 benefit Effects 0.000 description 1
230000015572 biosynthetic process Effects 0.000 description 1
210000001124 body fluid Anatomy 0.000 description 1
239000010839 body fluid Substances 0.000 description 1
230000003139 buffering effect Effects 0.000 description 1
229910052799 carbon Inorganic materials 0.000 description 1
239000003054 catalyst Substances 0.000 description 1
230000000973 chemotherapeutic effect Effects 0.000 description 1
239000012141 concentrate Substances 0.000 description 1
IQFVPQOLBLOTPF-HKXUKFGYSA-L congo red Chemical compound [Na+].[Na+].C1=CC=CC2=C(N)C(/N=N/C3=CC=C(C=C3)C3=CC=C(C=C3)/N=N/C3=C(C4=CC=CC=C4C(=C3)S([O-])(=O)=O)N)=CC(S([O-])(=O)=O)=C21 IQFVPQOLBLOTPF-HKXUKFGYSA-L 0.000 description 1
230000000875 corresponding effect Effects 0.000 description 1
XUJNEKJLAYXESH-UHFFFAOYSA-N cysteine Natural products SCC(N)C(O)=O XUJNEKJLAYXESH-UHFFFAOYSA-N 0.000 description 1
235000018417 cysteine Nutrition 0.000 description 1
229940127089 cytotoxic agent Drugs 0.000 description 1
235000013365 dairy product Nutrition 0.000 description 1
238000002845 discoloration Methods 0.000 description 1
VSSMQLIMSVAUDK-UHFFFAOYSA-L disodium;5-[(4-ethoxyphenyl)diazenyl]-2-[4-[(4-ethoxyphenyl)diazenyl]-2-sulfonatophenyl]sulfanylbenzenesulfonate Chemical compound [Na+].[Na+].C1=CC(OCC)=CC=C1N=NC(C=C1S([O-])(=O)=O)=CC=C1SC1=CC=C(N=NC=2C=CC(OCC)=CC=2)C=C1S([O-])(=O)=O VSSMQLIMSVAUDK-UHFFFAOYSA-L 0.000 description 1
BMYUQZABARGLAD-UHFFFAOYSA-L disodium;8-(4-methylanilino)-5-[[4-[(3-sulfonatophenyl)diazenyl]naphthalen-1-yl]diazenyl]naphthalene-1-sulfonate Chemical compound [Na+].[Na+].C1=CC(C)=CC=C1NC(C1=C(C=CC=C11)S([O-])(=O)=O)=CC=C1N=NC(C1=CC=CC=C11)=CC=C1N=NC1=CC=CC(S([O-])(=O)=O)=C1 BMYUQZABARGLAD-UHFFFAOYSA-L 0.000 description 1
235000013601 eggs Nutrition 0.000 description 1
238000002474 experimental method Methods 0.000 description 1
239000000284 extract Substances 0.000 description 1
239000004052 folic acid antagonist Substances 0.000 description 1
FETSQPAGYOVAQU-UHFFFAOYSA-N glyceryl palmitostearate Chemical compound OCC(O)CO.CCCCCCCCCCCCCCCC(O)=O.CCCCCCCCCCCCCCCCCC(O)=O FETSQPAGYOVAQU-UHFFFAOYSA-N 0.000 description 1
235000012907 honey Nutrition 0.000 description 1
238000010348 incorporation Methods 0.000 description 1
229940097275 indigo Drugs 0.000 description 1
COHYTHOBJLSHDF-UHFFFAOYSA-N indigo powder Natural products N1C2=CC=CC=C2C(=O)C1=C1C(=O)C2=CC=CC=C2N1 COHYTHOBJLSHDF-UHFFFAOYSA-N 0.000 description 1
230000005764 inhibitory process Effects 0.000 description 1
229910052500 inorganic mineral Inorganic materials 0.000 description 1
239000008101 lactose Substances 0.000 description 1
230000014759 maintenance of location Effects 0.000 description 1
238000002844 melting Methods 0.000 description 1
230000008018 melting Effects 0.000 description 1
239000002207 metabolite Substances 0.000 description 1
239000011707 mineral Substances 0.000 description 1
230000003472 neutralizing effect Effects 0.000 description 1
229910052757 nitrogen Inorganic materials 0.000 description 1
239000002777 nucleoside Substances 0.000 description 1
125000003835 nucleoside group Chemical group 0.000 description 1
230000035764 nutrition Effects 0.000 description 1
229960003068 ormetoprim Drugs 0.000 description 1
235000006408 oxalic acid Nutrition 0.000 description 1
229940049954 penicillin Drugs 0.000 description 1
150000002960 penicillins Chemical class 0.000 description 1
229960003531 phenolsulfonphthalein Drugs 0.000 description 1
230000008569 process Effects 0.000 description 1
230000000644 propagated effect Effects 0.000 description 1
OARRHUQTFTUEOS-UHFFFAOYSA-N safranin Chemical compound [Cl-].C=12C=C(N)C(C)=CC2=NC2=CC(C)=C(N)C=C2[N+]=1C1=CC=CC=C1 OARRHUQTFTUEOS-UHFFFAOYSA-N 0.000 description 1
150000003839 salts Chemical class 0.000 description 1
230000001235 sensitizing effect Effects 0.000 description 1
238000004904 shortening Methods 0.000 description 1
230000003584 silencer Effects 0.000 description 1
241000894007 species Species 0.000 description 1
229940124530 sulfonamide Drugs 0.000 description 1
150000003456 sulfonamides Chemical class 0.000 description 1
150000003464 sulfur compounds Chemical class 0.000 description 1
238000010998 test method Methods 0.000 description 1
235000019364 tetracycline Nutrition 0.000 description 1
150000003522 tetracyclines Chemical class 0.000 description 1
229940040944 tetracyclines Drugs 0.000 description 1
GMMAPXRGRVJYJY-UHFFFAOYSA-J tetrasodium 4-acetamido-5-hydroxy-6-[[7-sulfonato-4-[(4-sulfonatophenyl)diazenyl]naphthalen-1-yl]diazenyl]naphthalene-1,7-disulfonate Chemical compound [Na+].[Na+].[Na+].[Na+].OC1=C2C(NC(=O)C)=CC=C(S([O-])(=O)=O)C2=CC(S([O-])(=O)=O)=C1N=NC(C1=CC(=CC=C11)S([O-])(=O)=O)=CC=C1N=NC1=CC=C(S([O-])(=O)=O)C=C1 GMMAPXRGRVJYJY-UHFFFAOYSA-J 0.000 description 1
WSWJIZXMAUYHOE-UHFFFAOYSA-N tetroxoprim Chemical compound C1=C(OC)C(OCCOC)=C(OC)C=C1CC1=CN=C(N)N=C1N WSWJIZXMAUYHOE-UHFFFAOYSA-N 0.000 description 1
229960004809 tetroxoprim Drugs 0.000 description 1
229950003937 tolonium Drugs 0.000 description 1
HNONEKILPDHFOL-UHFFFAOYSA-M tolonium chloride Chemical compound [Cl-].C1=C(C)C(N)=CC2=[S+]C3=CC(N(C)C)=CC=C3N=C21 HNONEKILPDHFOL-UHFFFAOYSA-M 0.000 description 1
238000012546 transfer Methods 0.000 description 1
239000012780 transparent material Substances 0.000 description 1
239000012137 tryptone Substances 0.000 description 1
PEAGNRWWSMMRPZ-UHFFFAOYSA-L woodstain scarlet Chemical compound [Na+].[Na+].OC1=CC=C2C=C(S([O-])(=O)=O)C=C(S([O-])(=O)=O)C2=C1N=NC(C=C1)=CC=C1N=NC1=CC=CC=C1 PEAGNRWWSMMRPZ-UHFFFAOYSA-L 0.000 description 1

Classifications

- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/02—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving viable microorganisms
- C12Q1/18—Testing for antimicrobial activity of a material

Landscapes

Chemical & Material Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
Engineering & Computer Science (AREA)
Zoology (AREA)
Wood Science & Technology (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Molecular Biology (AREA)
Bioinformatics & Cheminformatics (AREA)
Immunology (AREA)
Microbiology (AREA)
Biophysics (AREA)
Analytical Chemistry (AREA)
Physics & Mathematics (AREA)
Toxicology (AREA)
Biochemistry (AREA)
Biotechnology (AREA)
General Engineering & Computer Science (AREA)
General Health & Medical Sciences (AREA)
Genetics & Genomics (AREA)
Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
Investigating Or Analysing Biological Materials (AREA)
Investigating Or Analyzing Non-Biological Materials By The Use Of Chemical Means (AREA)
Micro-Organisms Or Cultivation Processes Thereof (AREA)

SK1234-96A 1995-02-01 1996-02-01 A rapid microbiological test for the detection of antibacterial compounds SK123496A3 (en)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
EP95200243		1995-02-01
PCT/EP1996/000488 WO1996023901A1 (fr)	1995-02-01	1996-02-01	Test microbiologique rapide de detection de composes antibacteriens

Publications (1)

Publication Number	Publication Date
SK123496A3 true SK123496A3 (en)	1997-07-09

Family

ID=8219988

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
SK1234-96A SK123496A3 (en)	1995-02-01	1996-02-01	A rapid microbiological test for the detection of antibacterial compounds

Country Status (18)

Country	Link
US (1)	US6867015B1 (fr)
EP (1)	EP0755456B1 (fr)
JP (1)	JPH09511150A (fr)
AT (1)	ATE197477T1 (fr)
AU (1)	AU693993B2 (fr)
BG (1)	BG100882A (fr)
BR (1)	BR9603963A (fr)
CA (1)	CA2186728A1 (fr)
CZ (1)	CZ284196A3 (fr)
DE (1)	DE69610879T2 (fr)
ES (1)	ES2153562T3 (fr)
HU (1)	HUP9602995A2 (fr)
NO (1)	NO964142L (fr)
NZ (1)	NZ301691A (fr)
PL (1)	PL184460B1 (fr)
SK (1)	SK123496A3 (fr)
WO (1)	WO1996023901A1 (fr)
ZA (1)	ZA96786B (fr)

Families Citing this family (22)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
EP0755456B1 (fr)	1995-02-01	2000-11-08	Dsm N.V.	Test microbiologique rapide de detection de composes antibacteriens
CN100375788C (zh) *	2003-07-02	2008-03-19	帝斯曼知识产权资产管理有限公司	用于测定流体中是否存在抗生素的经过改进的检验系统
PL1639122T3 (pl) *	2003-07-02	2009-07-31	Dsm Ip Assets Bv	Ulepszony zestaw testowy do oznaczania obecności antybiotyków w płynach
EP1664330B1 (fr) *	2003-09-11	2008-11-19	DSM IP Assets B.V.	Sang et urine essai
ATE528389T1 (de) *	2003-11-18	2011-10-15	Charm Sciences Inc	Hemmtestverfahren und -vorrichtung zum nachweis von antibiotika
EP1766046B1 (fr)	2004-06-02	2010-10-20	DSM IP Assets B.V.	Oligosaccharides dans un système d'essai pour déterminer la présence d'une antibiotique dans un fluide
ES2263361B1 (es) *	2004-11-30	2007-11-01	Universidad De Zaragoza	Metodo de deteccion de residuos de antibioticos y otros compuestos antibacterianos.
US8476064B2 (en) *	2006-05-09	2013-07-02	Charm Sciences, Inc.	Inhibition assay method and device for detection of antibiotics
EP2365968B1 (fr)	2007-09-29	2018-08-22	Timothy James Williams	Composition et procédé de modification de la fonction du sperme et d'augmentation du taux du genre mâle chez les mammifères
CN102656275A (zh) *	2009-07-01	2012-09-05	生物梅里埃有限公司	用于中和培养基中的抗生素的方法
WO2013037888A1 (fr)	2011-09-16	2013-03-21	Dsm Ip Assets B.V.	Procédé de détection d'un analyte
WO2013037887A1 (fr)	2011-09-16	2013-03-21	Dsm Ip Assets B.V.	Immunoessai compétitif permettant de détecter des antibiotiques
EP2756306B1 (fr)	2011-09-16	2019-08-21	DSM IP Assets B.V.	Immunoassai pour la détection des antibiotiques
WO2013037886A1 (fr)	2011-09-16	2013-03-21	Dsm Ip Assets B.V.	Immunoessai permettant de détecter des antibiotiques
EA201400482A1 (ru) *	2011-10-18	2014-09-30	ДСМ АйПи АССЕТС Б.В.	Способ определения присутствия антибиотика в жидкости
JP5954640B2 (ja) *	2012-10-25	2016-07-20	学校法人福岡大学	感染評価系モデル
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- 1996-02-01 EP EP96902983A patent/EP0755456B1/fr not_active Revoked
- 1996-02-01 JP JP8523277A patent/JPH09511150A/ja active Pending
- 1996-02-01 BR BR9603963A patent/BR9603963A/pt not_active Application Discontinuation
- 1996-02-01 US US08/704,747 patent/US6867015B1/en not_active Expired - Fee Related
- 1996-02-01 NZ NZ301691A patent/NZ301691A/en unknown
- 1996-02-01 CA CA002186728A patent/CA2186728A1/fr not_active Abandoned
- 1996-02-01 AU AU47180/96A patent/AU693993B2/en not_active Ceased
- 1996-02-01 DE DE69610879T patent/DE69610879T2/de not_active Revoked
- 1996-02-01 HU HU9602995A patent/HUP9602995A2/hu unknown
- 1996-02-01 AT AT96902983T patent/ATE197477T1/de not_active IP Right Cessation
- 1996-02-01 ZA ZA96786A patent/ZA96786B/xx unknown
- 1996-02-01 CZ CZ962841A patent/CZ284196A3/cs unknown
- 1996-02-01 WO PCT/EP1996/000488 patent/WO1996023901A1/fr not_active Ceased
- 1996-02-01 SK SK1234-96A patent/SK123496A3/sk unknown
- 1996-02-01 PL PL96316582A patent/PL184460B1/pl not_active IP Right Cessation
- 1996-02-01 ES ES96902983T patent/ES2153562T3/es not_active Expired - Lifetime
- 1996-09-30 NO NO964142A patent/NO964142L/no unknown
- 1996-10-01 BG BG100882A patent/BG100882A/xx unknown

Also Published As

Publication number	Publication date
EP0755456A1 (fr)	1997-01-29
ES2153562T3 (es)	2001-03-01
US6867015B1 (en)	2005-03-15
NO964142D0 (no)	1996-09-30
NZ301691A (en)	1997-03-24
NO964142L (no)	1996-11-20
HUP9602995A2 (en)	1997-05-28
AU4718096A (en)	1996-08-21
CZ284196A3 (en)	1997-03-12
HU9602995D0 (en)	1997-01-28
DE69610879T2 (de)	2001-05-17
PL184460B1 (pl)	2002-10-31
JPH09511150A (ja)	1997-11-11
BR9603963A (pt)	1997-10-07
PL316582A1 (en)	1997-01-20
ZA96786B (en)	1996-08-12
CA2186728A1 (fr)	1996-08-08
MX9604494A (es)	1997-11-29
ATE197477T1 (de)	2000-11-11
DE69610879D1 (de)	2000-12-14
AU693993B2 (en)	1998-07-09
EP0755456B1 (fr)	2000-11-08
BG100882A (en)	1997-08-29
WO1996023901A1 (fr)	1996-08-08

Publication	Publication Date	Title
SK123496A3 (en)	1997-07-09	A rapid microbiological test for the detection of antibacterial compounds
EP0871854B1 (fr)	2003-06-04	Milieu de detection d'enterococci dans un echantillon
JPH07505788A (ja)	1995-06-29	液体中の抗菌性化合物の残留物検出用ユニット
US6737266B1 (en)	2004-05-18	Devices and methods for microorganism detection
FI67725B (fi)	1985-01-31	Foerfarande foer framstaellning av enheter avsedda foer bestaemning av antibiotika- och sulfarester i biologiska vaetskor och framstaellda enheter
US5494805A (en)	1996-02-27	Unit for the detection of residues of antibacterial compounds in liquids
FI57128C (fi)	1980-06-10	Saett att identifiera mikroorganismer
EP1403378B1 (fr)	2008-02-27	Milieu pour détecter des microbes cibles dans un échantillon
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EP1222469A2 (fr)	2002-07-17	Detection de residus antimicrobiens dans les oeufs
MXPA96004494A (en)	1998-07-03	A rapid microbiological test for the detection of antibacteria compounds
Taylor	1998	Recovery of human mycoplasmas
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Joy	0	Naveena Varghese
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