SK281472B6 - Použitie lys-plazminogénu na prípravu farmaceutickej kompozície - Google Patents

Použitie lys-plazminogénu na prípravu farmaceutickej kompozície Download PDF

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Publication number
SK281472B6
SK281472B6 SK798-94A SK79894A SK281472B6 SK 281472 B6 SK281472 B6 SK 281472B6 SK 79894 A SK79894 A SK 79894A SK 281472 B6 SK281472 B6 SK 281472B6
Authority
SK
Slovakia
Prior art keywords
plasminogen
lys
ischemia
reperfusion
reperfusion injury
Prior art date
Application number
SK798-94A
Other languages
English (en)
Slovak (sk)
Other versions
SK79894A3 (en
Inventor
Johann Eibl
Ludwig Pichler
Hans-Peter Schwarz
Original Assignee
Baxter Aktiengesellschaft
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Baxter Aktiengesellschaft filed Critical Baxter Aktiengesellschaft
Publication of SK79894A3 publication Critical patent/SK79894A3/sk
Publication of SK281472B6 publication Critical patent/SK281472B6/sk

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Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/43Enzymes; Proenzymes; Derivatives thereof
    • A61K38/46Hydrolases (3)
    • A61K38/48Hydrolases (3) acting on peptide bonds (3.4)
    • A61K38/482Serine endopeptidases (3.4.21)
    • A61K38/484Plasmin (3.4.21.7)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/10Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Immunology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Epidemiology (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Farming Of Fish And Shellfish (AREA)
  • Electrotherapy Devices (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)
  • Medicines Containing Plant Substances (AREA)
  • External Artificial Organs (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
SK798-94A 1993-07-02 1994-07-01 Použitie lys-plazminogénu na prípravu farmaceutickej kompozície SK281472B6 (sk)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US8803393A 1993-07-02 1993-07-02

Publications (2)

Publication Number Publication Date
SK79894A3 SK79894A3 (en) 1995-05-10
SK281472B6 true SK281472B6 (sk) 2001-04-09

Family

ID=22208925

Family Applications (1)

Application Number Title Priority Date Filing Date
SK798-94A SK281472B6 (sk) 1993-07-02 1994-07-01 Použitie lys-plazminogénu na prípravu farmaceutickej kompozície

Country Status (19)

Country Link
US (2) US5520912A (de)
EP (1) EP0631786B1 (de)
JP (1) JP2784146B2 (de)
AT (2) ATE167400T1 (de)
AU (1) AU680492B2 (de)
CA (1) CA2127199C (de)
CZ (1) CZ283352B6 (de)
DE (1) DE69411084T2 (de)
DK (1) DK0631786T3 (de)
ES (1) ES2119934T3 (de)
GR (1) GR3027778T3 (de)
HR (1) HRP940381B1 (de)
HU (1) HU217961B (de)
NO (1) NO942367L (de)
PL (1) PL304061A1 (de)
RU (1) RU2153353C2 (de)
SI (1) SI0631786T1 (de)
SK (1) SK281472B6 (de)
ZA (1) ZA944522B (de)

Families Citing this family (25)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE4411143C2 (de) * 1994-03-30 1996-08-01 Immuno Ag Thrombosemittel
ATE349226T1 (de) * 1998-09-29 2007-01-15 Leuven Res & Dev Vzw Verwendung von verbindungen die alpha2- antiplasmin in vivo reduzieren zur herstellung einer zusammensetzung zur behandlung ischämischer schlaganfälle
EP1062953A1 (de) * 1999-06-22 2000-12-27 Leuven Research & Development vzw Verwendung von Verbindungen, die Alpha2-Antiplasmin in vivo reduzieren, zur Herstellung einer Zusammensetzung zur Behandlung ischämischer Schlaganfälle
WO2000041714A1 (en) * 1999-01-19 2000-07-20 Bristol-Myers Squibb Company Method for determining care and prevention pathways for clinical management of wounds
US7184963B1 (en) 1999-01-19 2007-02-27 Bristol-Myers Squibb Company Method for determining care and prevention pathways for clinical management of wounds
AU3173301A (en) * 2000-02-11 2001-08-20 European Molecular Biology Laboratory Methods and compositions for treatment of alzheimer's disease by enhancing plasmin or plasmin-like activity
US20050124036A1 (en) * 2002-02-06 2005-06-09 Rudy Susilo Method for producing recombinant proteins in micro-organisms
AU2003252039A1 (en) * 2002-07-23 2004-02-09 Vegenics Limited Methods and compositions for activating or inhibiting vegf-d and vegf-c
PE20050438A1 (es) * 2003-10-20 2005-06-14 Esperion Therapeutics Inc Formulas farmaceuticas, metodos y regimenes de dosificacion para el tratamiento y la prevencion de sindromes coronarios agudos
RU2341256C1 (ru) * 2007-03-26 2008-12-20 Государственное Образовательное Учреждение Высшего Профессионального Образования Амурская Государственная Медицинская Академия Росздрава Способ профилактики реперфузионных осложнений у пациентов, оперированных по поводу хронической ишемии нижних конечностей
RU2411911C1 (ru) * 2009-07-02 2011-02-20 Клиника государственного образовательного учреждения высшего профессионального образования "Челябинская государственная медицинская академия Федерального агентства по здравоохранению и социальному развитию"(Клиника ГОУ ВПО ЧелГМА Роздрава) Способ прогнозирования характера течения реперфузионного синдрома после поэтапного хирургического лечения сонных артерий у пациентов с симптомными бикаротидными стенозами
KR20120050442A (ko) 2009-07-10 2012-05-18 쓰롬보제닉스 엔.브이. 플라스미노겐 및 플라스민의 변이체
US20120189609A1 (en) 2009-08-28 2012-07-26 Thrombogenics Nv Improvement to trabeculectomy
EP2661493B1 (de) 2011-01-05 2016-03-30 ThromboGenics N.V. Plasminogen- und plasminvarianten
JP6000353B2 (ja) 2011-08-12 2016-09-28 スロンボジェニックス・ナムローゼ・フェンノートシャップThromboGenics NV プラスミノーゲンおよびプラスミンの変異体
US10531655B2 (en) 2011-12-02 2020-01-14 The Regents Of The University Of California Reperfusion protection solution and uses thereof
TWI677348B (zh) * 2016-12-15 2019-11-21 大陸商深圳瑞健生命科學研究院有限公司 一種改善心臟病變的方法
WO2018107686A1 (zh) 2016-12-15 2018-06-21 深圳瑞健生命科学研究院有限公司 一种治疗动脉粥样硬化及其并发症的方法
JP7168990B2 (ja) 2016-12-15 2022-11-10 タレンゲン インターナショナル リミテッド 肥満症を予防および治療するための方法および薬物
TWI868051B (zh) * 2017-06-23 2025-01-01 美商波麥堤克生物治療股份有限公司 與pai-1過表現相關之病狀的纖維蛋白溶酶原治療
RU2729788C2 (ru) * 2018-09-04 2020-08-12 Федеральное государственное бюджетное учреждение науки "Федеральный исследовательский центр "Пущинский научный центр биологических исследований Российской академии наук" Средство, его применение и способ повышения устойчивости организма млекопитающих к ишемически-реперфузионному поражению тонкого кишечника
AU2020212404B2 (en) 2019-01-24 2025-11-27 Previpharma Consulting Gmbh Plasminogen for treating and preventing microthrombosis
SG11202110554YA (en) * 2019-04-12 2021-10-28 Uglk Science Ab Method and apparatus for reconditioning kidneys
SG11202110553PA (en) * 2019-04-12 2021-10-28 Uglx Res Ab Method and apparatus for reconditioning organs
CN114642722A (zh) * 2020-12-18 2022-06-21 四川大学华西医院 纤溶酶原用于制备促进血管新生的药物中的用途

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0028489B1 (de) * 1979-11-05 1983-10-05 Beecham Group Plc Enzym-Derivate und ihre Herstellung
DE3715662A1 (de) * 1986-05-12 1987-11-19 Wellcome Found Neue pharmazeutische anwendung
JP2764264B2 (ja) * 1987-10-01 1998-06-11 株式会社ミドリ十字 線溶活性増強剤
US5084274A (en) * 1987-11-17 1992-01-28 Scripps Clinic And Research Foundation Inhibition of arterial thrombotic occlusion or thromboembolism
US5256642A (en) * 1988-04-01 1993-10-26 The Johns Hopkins University Compositions of soluble complement receptor 1 (CR1) and a thrombolytic agent, and the methods of use thereof
AT390801B (de) * 1988-07-28 1990-07-10 Immuno Ag Verfahren zur herstellung von lys-plasminogen
US5358936A (en) * 1990-08-03 1994-10-25 Paul Gordon Anionic furanose derivatives, methods of making and using the same
AT402367B (de) * 1990-10-11 1997-04-25 Immuno Ag Pharmazeutische zubereitung auf basis von lys-plasminogen

Also Published As

Publication number Publication date
AT407706B (de) 2001-05-25
RU94022754A (ru) 1996-08-10
ZA944522B (en) 1995-02-23
NO942367L (no) 1995-01-03
HRP940381B1 (en) 1999-06-30
HU9401983D0 (en) 1994-09-28
US5597800A (en) 1997-01-28
CZ161394A3 (en) 1995-01-18
JPH07145076A (ja) 1995-06-06
ATE167400T1 (de) 1998-07-15
SI0631786T1 (en) 1998-10-31
HUT67225A (en) 1995-03-28
SK79894A3 (en) 1995-05-10
US5520912A (en) 1996-05-28
GR3027778T3 (en) 1998-11-30
NO942367D0 (de) 1994-06-21
CZ283352B6 (cs) 1998-03-18
CA2127199C (en) 2000-11-28
DK0631786T3 (da) 1999-04-06
PL304061A1 (en) 1995-01-09
AU6485494A (en) 1995-01-12
ATA131094A (de) 2000-10-15
HRP940381A2 (en) 1997-04-30
JP2784146B2 (ja) 1998-08-06
ES2119934T3 (es) 1998-10-16
RU2153353C2 (ru) 2000-07-27
DE69411084D1 (de) 1998-07-23
AU680492B2 (en) 1997-07-31
CA2127199A1 (en) 1995-01-03
EP0631786B1 (de) 1998-06-17
HU217961B (hu) 2000-05-28
EP0631786A1 (de) 1995-01-04
DE69411084T2 (de) 1998-12-03

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