ATA131094A - Prevention und behandlung ischemischer vorfälle und hieraus resultierender perfusionsverletzungen - Google Patents

Prevention und behandlung ischemischer vorfälle und hieraus resultierender perfusionsverletzungen

Info

Publication number
ATA131094A
ATA131094A AT0131094A AT131094A ATA131094A AT A131094 A ATA131094 A AT A131094A AT 0131094 A AT0131094 A AT 0131094A AT 131094 A AT131094 A AT 131094A AT A131094 A ATA131094 A AT A131094A
Authority
AT
Austria
Prior art keywords
plasminogen
lys
treatment
ischemical
incidents
Prior art date
Application number
AT0131094A
Other languages
English (en)
Other versions
AT407706B (de
Inventor
Johann Dr Eibl
Ludwig Pichler
Hans-Peter Schwarz
Original Assignee
Immuno Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Immuno Ag filed Critical Immuno Ag
Publication of ATA131094A publication Critical patent/ATA131094A/de
Application granted granted Critical
Publication of AT407706B publication Critical patent/AT407706B/de

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/43—Enzymes; Proenzymes; Derivatives thereof
    • A61K38/46—Hydrolases (3)
    • A61K38/48—Hydrolases (3) acting on peptide bonds (3.4)
    • A61K38/482—Serine endopeptidases (3.4.21)
    • A61K38/484—Plasmin (3.4.21.7)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Epidemiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Immunology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Organic Chemistry (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)
  • Medicines Containing Plant Substances (AREA)
  • Farming Of Fish And Shellfish (AREA)
  • Electrotherapy Devices (AREA)
  • External Artificial Organs (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
AT0131094A 1993-07-02 1994-07-01 Prevention und behandlung ischemischer vorfälle und hieraus resultierender perfusionsverletzungen AT407706B (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US8803393A 1993-07-02 1993-07-02

Publications (2)

Publication Number Publication Date
ATA131094A true ATA131094A (de) 2000-10-15
AT407706B AT407706B (de) 2001-05-25

Family

ID=22208925

Family Applications (2)

Application Number Title Priority Date Filing Date
AT94110267T ATE167400T1 (de) 1993-07-02 1994-07-01 Lys-plasminogen in der verhütung und behandlung von ischämie und reperfusionschäden
AT0131094A AT407706B (de) 1993-07-02 1994-07-01 Prevention und behandlung ischemischer vorfälle und hieraus resultierender perfusionsverletzungen

Family Applications Before (1)

Application Number Title Priority Date Filing Date
AT94110267T ATE167400T1 (de) 1993-07-02 1994-07-01 Lys-plasminogen in der verhütung und behandlung von ischämie und reperfusionschäden

Country Status (19)

Country Link
US (2) US5520912A (de)
EP (1) EP0631786B1 (de)
JP (1) JP2784146B2 (de)
AT (2) ATE167400T1 (de)
AU (1) AU680492B2 (de)
CA (1) CA2127199C (de)
CZ (1) CZ283352B6 (de)
DE (1) DE69411084T2 (de)
DK (1) DK0631786T3 (de)
ES (1) ES2119934T3 (de)
GR (1) GR3027778T3 (de)
HR (1) HRP940381B1 (de)
HU (1) HU217961B (de)
NO (1) NO942367L (de)
PL (1) PL304061A1 (de)
RU (1) RU2153353C2 (de)
SI (1) SI0631786T1 (de)
SK (1) SK281472B6 (de)
ZA (1) ZA944522B (de)

Families Citing this family (25)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE4411143C2 (de) * 1994-03-30 1996-08-01 Immuno Ag Thrombosemittel
DE69934595T2 (de) * 1998-09-29 2007-10-04 Leuven Research & Development V.Z.W. Verwendung von verbindungen,die alpha2-antiplasmin in vivo reduzieren,zur herstellung einer zusammensetzung zur behandlung ischämischer schlaganfälle
EP1062953A1 (de) * 1999-06-22 2000-12-27 Leuven Research & Development vzw Verwendung von Verbindungen, die Alpha2-Antiplasmin in vivo reduzieren, zur Herstellung einer Zusammensetzung zur Behandlung ischämischer Schlaganfälle
US7184963B1 (en) 1999-01-19 2007-02-27 Bristol-Myers Squibb Company Method for determining care and prevention pathways for clinical management of wounds
EP1169055A4 (de) * 1999-01-19 2009-10-21 Bristol Myers Squibb Co Methode zur bestimmung von pflegeabläufen und vorbeugungsmassnahmen zur klinischen behandlung von wunden
AU3173301A (en) * 2000-02-11 2001-08-20 European Molecular Biology Laboratory Methods and compositions for treatment of alzheimer's disease by enhancing plasmin or plasmin-like activity
US20050124036A1 (en) * 2002-02-06 2005-06-09 Rudy Susilo Method for producing recombinant proteins in micro-organisms
WO2004009773A2 (en) * 2002-07-23 2004-01-29 Ludwig Institute For Cancer Research Methods and compositions for activating or inhibiting vegf-d and vegf-c
PE20050438A1 (es) * 2003-10-20 2005-06-14 Esperion Therapeutics Inc Formulas farmaceuticas, metodos y regimenes de dosificacion para el tratamiento y la prevencion de sindromes coronarios agudos
RU2341256C1 (ru) * 2007-03-26 2008-12-20 Государственное Образовательное Учреждение Высшего Профессионального Образования Амурская Государственная Медицинская Академия Росздрава Способ профилактики реперфузионных осложнений у пациентов, оперированных по поводу хронической ишемии нижних конечностей
RU2411911C1 (ru) * 2009-07-02 2011-02-20 Клиника государственного образовательного учреждения высшего профессионального образования "Челябинская государственная медицинская академия Федерального агентства по здравоохранению и социальному развитию"(Клиника ГОУ ВПО ЧелГМА Роздрава) Способ прогнозирования характера течения реперфузионного синдрома после поэтапного хирургического лечения сонных артерий у пациентов с симптомными бикаротидными стенозами
US9226953B2 (en) 2009-07-10 2016-01-05 Thrombogenics Nv Variants of plasminogen and plasmin
EP2480249B1 (de) 2009-08-28 2015-01-28 ThromboGenics N.V. Plasmin zur Behandlung von Filtrationsfehlern nach Trabeculektomie
ES2583082T3 (es) 2011-01-05 2016-09-19 Thrombogenics N.V. Variantes de plasminógeno y plasmina
RU2604810C2 (ru) 2011-08-12 2016-12-10 Тромбодженикс Н.В. Варианты плазминогена и плазмина
US10531655B2 (en) 2011-12-02 2020-01-14 The Regents Of The University Of California Reperfusion protection solution and uses thereof
WO2018107690A1 (zh) 2016-12-15 2018-06-21 深圳瑞健生命科学研究院有限公司 一种预防和治疗肥胖症的方法
EP3556385A4 (de) * 2016-12-15 2020-12-30 Talengen International Limited Verfahren zur verringerung von herzerkrankungen
JP7168990B2 (ja) 2016-12-15 2022-11-10 タレンゲン インターナショナル リミテッド 肥満症を予防および治療するための方法および薬物
TWI868051B (zh) 2017-06-23 2025-01-01 美商波麥堤克生物治療股份有限公司 與pai-1過表現相關之病狀的纖維蛋白溶酶原治療
RU2729788C2 (ru) * 2018-09-04 2020-08-12 Федеральное государственное бюджетное учреждение науки "Федеральный исследовательский центр "Пущинский научный центр биологических исследований Российской академии наук" Средство, его применение и способ повышения устойчивости организма млекопитающих к ишемически-реперфузионному поражению тонкого кишечника
CN113597313A (zh) 2019-01-24 2021-11-02 先觉药业咨询公司 用于治疗和预防微血栓形成的纤溶酶原
KR102897177B1 (ko) * 2019-04-12 2025-12-05 유지엘엑스 리서치 에이비 장기 복구를 위한 방법 및 장치
KR102806125B1 (ko) * 2019-04-12 2025-05-09 유지엘케이 사이언스 에이비 신장 이식을 위한 방법 및 장치
CN114642722A (zh) * 2020-12-18 2022-06-21 四川大学华西医院 纤溶酶原用于制备促进血管新生的药物中的用途

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3065190D1 (en) * 1979-11-05 1983-11-10 Beecham Group Plc Enzyme derivatives, and their preparation
BE1001425A4 (fr) * 1986-05-12 1989-10-31 Wellcome Found Utilisation de l'activateur tissulaire du plasminogene, son association avec une superoxyde-dismutase et formulation pharmaceutique contenant cette association.
JP2764264B2 (ja) * 1987-10-01 1998-06-11 株式会社ミドリ十字 線溶活性増強剤
US5084274A (en) * 1987-11-17 1992-01-28 Scripps Clinic And Research Foundation Inhibition of arterial thrombotic occlusion or thromboembolism
US5256642A (en) * 1988-04-01 1993-10-26 The Johns Hopkins University Compositions of soluble complement receptor 1 (CR1) and a thrombolytic agent, and the methods of use thereof
AT390801B (de) * 1988-07-28 1990-07-10 Immuno Ag Verfahren zur herstellung von lys-plasminogen
US5358936A (en) * 1990-08-03 1994-10-25 Paul Gordon Anionic furanose derivatives, methods of making and using the same
AT402367B (de) * 1990-10-11 1997-04-25 Immuno Ag Pharmazeutische zubereitung auf basis von lys-plasminogen

Also Published As

Publication number Publication date
EP0631786B1 (de) 1998-06-17
DE69411084T2 (de) 1998-12-03
SI0631786T1 (en) 1998-10-31
US5520912A (en) 1996-05-28
ZA944522B (en) 1995-02-23
PL304061A1 (en) 1995-01-09
RU2153353C2 (ru) 2000-07-27
HRP940381B1 (en) 1999-06-30
NO942367D0 (de) 1994-06-21
AU680492B2 (en) 1997-07-31
CA2127199C (en) 2000-11-28
HU9401983D0 (en) 1994-09-28
HU217961B (hu) 2000-05-28
HUT67225A (en) 1995-03-28
ATE167400T1 (de) 1998-07-15
AT407706B (de) 2001-05-25
CZ161394A3 (en) 1995-01-18
US5597800A (en) 1997-01-28
RU94022754A (ru) 1996-08-10
SK281472B6 (sk) 2001-04-09
HRP940381A2 (en) 1997-04-30
ES2119934T3 (es) 1998-10-16
AU6485494A (en) 1995-01-12
GR3027778T3 (en) 1998-11-30
CZ283352B6 (cs) 1998-03-18
NO942367L (no) 1995-01-03
DE69411084D1 (de) 1998-07-23
JP2784146B2 (ja) 1998-08-06
SK79894A3 (en) 1995-05-10
EP0631786A1 (de) 1995-01-04
CA2127199A1 (en) 1995-01-03
DK0631786T3 (da) 1999-04-06
JPH07145076A (ja) 1995-06-06

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