SK282594B6 - Spôsob prípravy tabletkového prípravku - Google Patents

Spôsob prípravy tabletkového prípravku Download PDF

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Publication number
SK282594B6
SK282594B6 SK1354-96A SK135496A SK282594B6 SK 282594 B6 SK282594 B6 SK 282594B6 SK 135496 A SK135496 A SK 135496A SK 282594 B6 SK282594 B6 SK 282594B6
Authority
SK
Slovakia
Prior art keywords
coating
amoxycillin
weight
tablet
clavulanate
Prior art date
Application number
SK1354-96A
Other languages
English (en)
Slovak (sk)
Other versions
SK135496A3 (en
Inventor
Creighton Pierce Conley
Nigel Philip Mccreath Davidson
Original Assignee
Smithkline Beecham Corporation
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=10754044&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=SK282594(B6) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Smithkline Beecham Corporation filed Critical Smithkline Beecham Corporation
Publication of SK135496A3 publication Critical patent/SK135496A3/sk
Publication of SK282594B6 publication Critical patent/SK282594B6/sk

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/42—Oxazoles
    • A61K31/424—Oxazoles condensed with heterocyclic ring systems, e.g. clavulanic acid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/425—Thiazoles
    • A61K31/429—Thiazoles condensed with heterocyclic ring systems
    • A61K31/43—Compounds containing 4-thia-1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula, e.g. penicillins, penems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
    • A61K9/2806—Coating materials
    • A61K9/2833—Organic macromolecular compounds
    • A61K9/2853—Organic macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, polyethylene oxide, poloxamers, poly(lactide-co-glycolide)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
    • A61K9/2806—Coating materials
    • A61K9/2833—Organic macromolecular compounds
    • A61K9/286—Polysaccharides, e.g. gums; Cyclodextrin
    • A61K9/2866—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
    • A61K9/2893—Tablet coating processes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
SK1354-96A 1994-04-23 1995-04-19 Spôsob prípravy tabletkového prípravku SK282594B6 (sk)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB9408117A GB9408117D0 (en) 1994-04-23 1994-04-23 Pharmaceutical formulations
PCT/EP1995/001463 WO1995028927A1 (en) 1994-04-23 1995-04-19 Polymer coated tablet comprising amoxycillin and clavulanate

Publications (2)

Publication Number Publication Date
SK135496A3 SK135496A3 (en) 1997-05-07
SK282594B6 true SK282594B6 (sk) 2002-10-08

Family

ID=10754044

Family Applications (1)

Application Number Title Priority Date Filing Date
SK1354-96A SK282594B6 (sk) 1994-04-23 1995-04-19 Spôsob prípravy tabletkového prípravku

Country Status (35)

Country Link
US (1) US6051255A (cs)
EP (5) EP1243267A3 (cs)
JP (1) JP3622975B2 (cs)
CN (1) CN1134258C (cs)
AP (2) AP564A (cs)
AT (6) ATE223706T1 (cs)
AU (1) AU684949B2 (cs)
BG (1) BG62842B1 (cs)
BR (1) BR9507502A (cs)
CA (1) CA2188496A1 (cs)
CZ (2) CZ11376U1 (cs)
DE (5) DE69521799T2 (cs)
DK (4) DK0758235T3 (cs)
DZ (1) DZ1876A1 (cs)
ES (4) ES2182754T3 (cs)
FI (1) FI964249A0 (cs)
GB (1) GB9408117D0 (cs)
GR (2) GR3035031T3 (cs)
HK (1) HK1050992A1 (cs)
HU (1) HU228399B1 (cs)
IL (1) IL113433A (cs)
MA (1) MA23528A1 (cs)
MY (1) MY115351A (cs)
NO (1) NO310703B1 (cs)
NZ (1) NZ285080A (cs)
OA (1) OA10377A (cs)
PL (1) PL316966A1 (cs)
PT (4) PT758235E (cs)
RO (1) RO116997B1 (cs)
RU (1) RU2152213C1 (cs)
SA (1) SA95160343B1 (cs)
SI (1) SI0758235T1 (cs)
SK (1) SK282594B6 (cs)
WO (1) WO1995028927A1 (cs)
ZA (1) ZA953236B (cs)

Families Citing this family (70)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9407386D0 (en) 1994-04-14 1994-06-08 Smithkline Beecham Plc Pharmaceutical formulation
GB9408117D0 (en) * 1994-04-23 1994-06-15 Smithkline Beecham Corp Pharmaceutical formulations
DZ2028A1 (fr) * 1995-05-03 2002-10-23 Smithkline Beecham Plc Médicaments destinés au traitement d'infections bactériennes en pédiatrie.
US20030109503A1 (en) * 1995-06-06 2003-06-12 Smithkline Beecham P.L.C. Pharmaceutical formulations comprising clavulanic acid alone or in combination with other beta-lactam antibiotics
EP1093812A3 (en) * 1995-09-07 2001-06-06 SmithKline Beecham Corporation Amoxycillin and clavulanate containing pharmaceutical formulation
AT403375B (de) * 1995-11-15 1998-01-26 Biochemie Gmbh Verfahren zur fällung von alkalisalzen der clavulansäure
TWI225402B (en) * 1996-03-13 2004-12-21 Biochemie Gmbh Auxiliary-free agglomerates
AT407701B (de) * 1996-08-12 2001-05-25 Biochemie Gmbh Zur direkttablettierung geeignete mischung, die als wesentliche komponenten amoxicillin-trihydrat und das kaliumsalz der clavulansäure enthält und verfahren zur herstellung dieser mischung
GB9613470D0 (en) 1996-06-27 1996-08-28 Ciba Geigy Ag Small solid oral dosage form
GB9616536D0 (en) * 1996-08-06 1996-09-25 Quadrant Holdings Cambridge Co-amoxiclav dosage form
GB9617780D0 (en) 1996-08-24 1996-10-02 Smithkline Beecham Plc Method of treatment
WO1998034598A2 (en) * 1997-02-07 1998-08-13 Gist-Brocades B.V. Homogeneous granulated formulations for dose sipping technology
US20030124187A1 (en) * 1997-02-14 2003-07-03 Smithkline Beecham Laboratoires Pharmaceutiques, Pharmaceutical formulations comprising amoxycillin and clavulanate
IL131201A (en) * 1997-02-14 2005-06-19 Smithkline Beecham Lab Pharmaceutical formulations comprising amoxycillin and clavulanate
EP1023065A1 (en) * 1997-08-29 2000-08-02 Dsm N.V. Granules free of excipients
US6395298B1 (en) 1997-10-31 2002-05-28 Pharmacia Corporation Gellan gum tablet coating
ATE260096T1 (de) 1999-04-01 2004-03-15 Dsm Ip Assets Bv Agglomerate durch kristallisation
US6294199B1 (en) * 1999-04-13 2001-09-25 Beecham Pharmaceuticals (Pte) Limited Method of treating a bacterial infection comprising administering amoxycillin
US6878386B1 (en) 1999-04-13 2005-04-12 Beecham Pharmaceuticals (Pte) Limited Method of treating a bacterial infection comprising amoxycillin and potassium clavulanate
KR100634937B1 (ko) * 1999-04-13 2006-10-17 비참 파마슈티컬스 (피티이) 리미티드 신규한 치료 방법
US7250176B1 (en) * 1999-04-13 2007-07-31 Beecham Pharmaceuticals (Pte) Limited Method of treating a bacterial infection
US20040038948A1 (en) 1999-12-07 2004-02-26 Uhrich Kathryn E. Therapeutic compositions and methods
GB9930578D0 (en) * 1999-12-23 2000-02-16 Smithkline Beecham Plc Pharmaceutical formulations
US6565882B2 (en) * 2000-02-24 2003-05-20 Advancis Pharmaceutical Corp Antibiotic composition with inhibitor
US6544555B2 (en) 2000-02-24 2003-04-08 Advancis Pharmaceutical Corp. Antibiotic product, use and formulation thereof
US6375982B1 (en) * 2000-07-05 2002-04-23 Capricorn Pharma, Inc. Rapid-melt semi-solid compositions, methods of making same and method of using same
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WO2002030392A2 (en) * 2000-10-12 2002-04-18 Beecham Pharmaceuticals (Pte) Limited Formulation containing amoxicillin
US6756057B2 (en) * 2000-10-12 2004-06-29 Beecham Pharmaceuticals (Pte) Limited Amoxicillin and potassium clavulanate dosage form
US6541014B2 (en) * 2000-10-13 2003-04-01 Advancis Pharmaceutical Corp. Antiviral product, use and formulation thereof
US20020068078A1 (en) * 2000-10-13 2002-06-06 Rudnic Edward M. Antifungal product, use and formulation thereof
US20020197314A1 (en) * 2001-02-23 2002-12-26 Rudnic Edward M. Anti-fungal composition
US20040156900A1 (en) * 2001-04-10 2004-08-12 Shanghvi Dilip Shantilal Time pulsed release composition
AU4061702A (en) * 2001-05-15 2003-04-03 Mcneil-Ppc, Inc. Dip coating compositions containing starch or dextrin
US20030070584A1 (en) * 2001-05-15 2003-04-17 Cynthia Gulian Dip coating compositions containing cellulose ethers
US8309118B2 (en) * 2001-09-28 2012-11-13 Mcneil-Ppc, Inc. Film forming compositions containing sucralose
WO2003066053A1 (en) * 2002-02-07 2003-08-14 Rutgers, The State University Antibiotic polymers
JP2005523276A (ja) * 2002-02-14 2005-08-04 グラクソ　グループ　リミテッド Ｎ−［（１−ｎ−ブチル−４−ピペリジニル）メチル］−３，４−ジヒドロ−２ｈ−［１，３］オキサジノ［３，２−ａ］インドール−１０−カルボキシアミド（ｓｂ２０７２６６）またはその塩および乾燥造粒操作を含む方法
GB0203528D0 (en) * 2002-02-14 2002-04-03 Glaxo Group Ltd Process and composition
US20060083759A1 (en) * 2002-07-17 2006-04-20 Aleksander Resman Stabilization of the profile of release of active substances from a formulation
US8637512B2 (en) 2002-07-29 2014-01-28 Glaxo Group Limited Formulations and method of treatment
KR100456833B1 (ko) * 2002-08-01 2004-11-10 주식회사 대웅 아목시실린 및 클라불라네이트를 함유하는 유핵정
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US8715727B2 (en) * 2004-07-02 2014-05-06 Shionogi Inc. Tablet for pulsed delivery
KR100638315B1 (ko) * 2004-07-23 2006-10-25 주식회사 대웅제약 다중 필름 코팅된 코어층을 갖는 클라불라네이트 및아목시실린-함유 유핵정
TWI367755B (en) 2005-05-20 2012-07-11 Sankyo Co Film coated product
KR100780553B1 (ko) * 2005-08-18 2007-11-29 한올제약주식회사 메트포르민 서방정 및 그의 제조방법
US8778924B2 (en) * 2006-12-04 2014-07-15 Shionogi Inc. Modified release amoxicillin products
US8357394B2 (en) 2005-12-08 2013-01-22 Shionogi Inc. Compositions and methods for improved efficacy of penicillin-type antibiotics
US8299052B2 (en) 2006-05-05 2012-10-30 Shionogi Inc. Pharmaceutical compositions and methods for improved bacterial eradication
CL2008003230A1 (es) * 2007-11-01 2009-11-27 Sanofi Aventis Healthcare Pty Ltd Composicion de recubrimiento de tableta que comprende polimero celulosico, plastificante, edulcorante y composicion de sabor en polvo la que comprende saborizante asociado con portador solido; fluido de recubrimiento de tableta que comprende dicha composicion; tableta farmaceutica; proceso de preparacion de dicha tableta.
JP2013505213A (ja) * 2009-09-18 2013-02-14 サノフイ 改善された安定性を有する（ｚ）−２−シアノ−３−ヒドロキシ−ブタ−２−エン酸−（４’−トリフルオロメチルフェニル）−アミド錠製剤
TR200909787A2 (tr) 2009-12-25 2011-07-21 Bi̇lgi̇ç Mahmut Üçüncü kuşak bir sefalosporin ve klavulanik asit içeren farmasötik formülasyonlar.
TR201000688A2 (tr) 2010-01-29 2011-08-22 B�Lg�� Mahmut Aktif madde olarak sefaklor ve klavulanik asit içeren efervesan formülasyonlar.
TR201000686A1 (tr) 2010-01-29 2011-08-22 B�Lg�� Mahmut Bakteriyel enfeksiyonların tedavisinde suda çözünebilir sefdinir ve klavulanik asit formülasyonları.@
TR201000687A1 (tr) 2010-01-29 2011-08-22 Bi̇lgi̇ç Mahmut Aktif madde olarak sefiksim ve klavulanik asit içeren efervesan formülasyonlar
JP6041591B2 (ja) * 2011-09-13 2016-12-14 大日本住友製薬株式会社 イルベサルタンとアムロジピンまたはその塩を含有する安定化された医薬組成物
US9387250B2 (en) 2013-03-15 2016-07-12 Rutgers, The State University Of New Jersey Therapeutic compositions for bone repair

Family Cites Families (9)

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Publication number Priority date Publication date Assignee Title
GB1241844A (en) 1968-08-23 1971-08-04 Beecham Group Ltd Penicillins
GB1508977A (en) 1974-04-20 1978-04-26 Beecham Group Ltd Beta-lactam antibiotic from streptomyces clavuligerus
US4098897A (en) * 1975-04-14 1978-07-04 Beecham Group Limited Anti bacterial agents
JO984B1 (en) 1977-10-11 1979-12-01 بيتشام غروب ليمتد A dry pharmaceutical compound with a suitable dosage unit for oral administration
NZ198241A (en) * 1980-09-27 1983-12-16 Beecham Group Ltd Tablet containing amoxycillin and potassium clavulanate
EP0080862B1 (en) * 1981-12-02 1985-09-25 Beecham Group Plc Pharmaceutical formulation comprising beta-lactam antibiotics
GB9408117D0 (en) * 1994-04-23 1994-06-15 Smithkline Beecham Corp Pharmaceutical formulations
KR100634937B1 (ko) * 1999-04-13 2006-10-17 비참 파마슈티컬스 (피티이) 리미티드 신규한 치료 방법
WO2002030392A2 (en) * 2000-10-12 2002-04-18 Beecham Pharmaceuticals (Pte) Limited Formulation containing amoxicillin

Also Published As

Publication number Publication date
AP564A (en) 1996-11-21
HU9602922D0 (en) 1996-12-30
GR3035031T3 (en) 2001-03-30
HK1021860A1 (en) 2000-07-07
NZ285080A (en) 1998-05-27
EP1093813A3 (en) 2001-05-30
HUT76335A (en) 1997-08-28
PT978276E (pt) 2003-01-31
FI964249L (fi) 1996-10-22
DE69521799T2 (de) 2002-06-13
ATE196845T1 (de) 2000-10-15
HK1050992A1 (en) 2003-07-18
EP0978276B1 (en) 2002-09-11
DE29522153U1 (de) 2000-04-06
RO116997B1 (ro) 2001-09-28
DE69528608D1 (de) 2002-11-21
BR9507502A (pt) 1997-09-02
CA2188496A1 (en) 1995-11-02
AP9500733A0 (en) 1995-04-30
CZ294168B6 (cs) 2004-10-13
EP0761218B1 (en) 2000-10-11
EP0978276A3 (en) 2000-04-12
JPH09512027A (ja) 1997-12-02
CN1149829A (zh) 1997-05-14
GR3036844T3 (en) 2002-01-31
DK0758235T3 (da) 2001-10-29
DK0761218T3 (da) 2000-12-18
CZ11376U1 (cs) 2001-07-12
WO1995028927A1 (en) 1995-11-02
NO964488L (no) 1996-12-17
AU684949B2 (en) 1998-01-08
ATE226074T1 (de) 2002-11-15
DK1093813T3 (da) 2003-02-17
PL316966A1 (en) 1997-03-03
EP1093813B1 (en) 2002-10-16
EP1093813A2 (en) 2001-04-25
HK1027024A1 (en) 2001-01-05
DE69519093D1 (de) 2000-11-16
ATE223706T1 (de) 2002-09-15
SA95160343B1 (ar) 2005-05-04
EP1243267A2 (en) 2002-09-25
PT761218E (pt) 2001-03-30
IL113433A0 (en) 1995-07-31
JP3622975B2 (ja) 2005-02-23
EP1243267A3 (en) 2002-10-30
NO310703B1 (no) 2001-08-20
CZ309096A3 (en) 1997-04-16
US6051255A (en) 2000-04-18
SK135496A3 (en) 1997-05-07
DE69521799D1 (de) 2001-08-23
EP0978276A2 (en) 2000-02-09
BG100933A (en) 1997-07-31
ES2152485T3 (es) 2001-02-01
DK0978276T3 (da) 2003-01-20
HK1036404A1 (en) 2002-01-04
NO964488D0 (no) 1996-10-22
ES2161288T3 (es) 2001-12-01
DZ1876A1 (fr) 2002-02-17
BG62842B1 (bg) 2000-09-29
AU2406895A (en) 1995-11-16
ES2180251T3 (es) 2003-02-01
HK1009936A1 (en) 1999-06-11
AT5350U1 (de) 2002-06-25
DE69528204D1 (de) 2002-10-17
FI964249A7 (fi) 1996-10-22
CN1134258C (zh) 2004-01-14
RU2152213C1 (ru) 2000-07-10
AP9600868A0 (en) 1996-10-31
OA10377A (en) 2001-11-21
EP0758235B1 (en) 2001-07-18
HU228399B1 (en) 2013-03-28
DE69519093T2 (de) 2001-07-19
SI0758235T1 (en) 2001-10-31
MA23528A1 (fr) 1995-12-31
ES2182754T3 (es) 2003-03-16
MY115351A (en) 2003-05-31
ZA953236B (en) 1995-12-27
AT5349U1 (de) 2002-06-25
DE69528204T2 (de) 2003-08-07
EP0758235A1 (en) 1997-02-19
GB9408117D0 (en) 1994-06-15
PT758235E (pt) 2001-10-31
DE69528608T2 (de) 2003-06-26
ATE203161T1 (de) 2001-08-15
IL113433A (en) 2003-06-24
PT1093813E (pt) 2003-02-28
EP0761218A1 (en) 1997-03-12
FI964249A0 (fi) 1996-10-22

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