SK34099A3 - Ptx sensitive g proteins, the production and use thereof - Google Patents

Ptx sensitive g proteins, the production and use thereof Download PDF

Info

Publication number: SK34099A3
Authority: SK; Slovakia
Prior art keywords: protein; nucleic acid; acid sequence; disease; ser
Prior art date: 1996-09-13

Application number

SK340-99A

Other languages

English (en)

Slovak (sk)

Inventor

Winfried Siffert

Original Assignee

Winfried Siffert

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1996-09-13

Filing date

1997-08-29

Publication date

2000-05-16

1997-08-29 Application filed by Winfried Siffert filed Critical Winfried Siffert

2000-05-16 Publication of SK34099A3 publication Critical patent/SK34099A3/sk

Links

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102000052301 human GNAZ Human genes 0.000 claims abstract description 7
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108091000058 GTP-Binding Proteins 0.000 claims description 44
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MASXKPLGZRMBJF-MVSGICTGSA-N mastoparan Chemical compound CC[C@H](C)[C@H](N)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](C)C(=O)N[C@@H](C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](C)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CC(C)C)C(N)=O MASXKPLGZRMBJF-MVSGICTGSA-N 0.000 description 1
108010019084 mastoparan Proteins 0.000 description 1
239000000463 material Substances 0.000 description 1
230000001404 mediated effect Effects 0.000 description 1
230000001394 metastastic effect Effects 0.000 description 1
210000000822 natural killer cell Anatomy 0.000 description 1
201000001119 neuropathy Diseases 0.000 description 1
230000007823 neuropathy Effects 0.000 description 1
238000003199 nucleic acid amplification method Methods 0.000 description 1
208000033808 peripheral neuropathy Diseases 0.000 description 1
108091008695 photoreceptors Proteins 0.000 description 1
230000008488 polyadenylation Effects 0.000 description 1
201000011461 pre-eclampsia Diseases 0.000 description 1
238000002203 pretreatment Methods 0.000 description 1
102000004196 processed proteins & peptides Human genes 0.000 description 1
108091008146 restriction endonucleases Proteins 0.000 description 1
230000000250 revascularization Effects 0.000 description 1
238000012216 screening Methods 0.000 description 1
108010048397 seryl-lysyl-leucine Proteins 0.000 description 1
241000894007 species Species 0.000 description 1
230000009870 specific binding Effects 0.000 description 1
208000010110 spontaneous platelet aggregation Diseases 0.000 description 1
208000037804 stenosis Diseases 0.000 description 1
230000036262 stenosis Effects 0.000 description 1
230000004936 stimulating effect Effects 0.000 description 1
230000000638 stimulation Effects 0.000 description 1
239000000126 substance Substances 0.000 description 1
239000003053 toxin Substances 0.000 description 1
231100000765 toxin Toxicity 0.000 description 1
238000013519 translation Methods 0.000 description 1
230000005748 tumor development Effects 0.000 description 1
230000002792 vascular Effects 0.000 description 1
108010027345 wheylin-1 peptide Proteins 0.000 description 1
230000029663 wound healing Effects 0.000 description 1

Classifications

- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
- C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
- C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
- C07K14/4722—G-proteins
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/12—Drugs for disorders of the urinary system of the kidneys
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/04—Antineoplastic agents specific for metastasis
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
- A01K2217/00—Genetically modified animals
- A01K2217/05—Animals comprising random inserted nucleic acids (transgenic)
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Organic Chemistry (AREA)
Engineering & Computer Science (AREA)
General Health & Medical Sciences (AREA)
Medicinal Chemistry (AREA)
Bioinformatics & Cheminformatics (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Pharmacology & Pharmacy (AREA)
General Chemical & Material Sciences (AREA)
Animal Behavior & Ethology (AREA)
Chemical Kinetics & Catalysis (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Genetics & Genomics (AREA)
Biomedical Technology (AREA)
Diabetes (AREA)
Zoology (AREA)
Molecular Biology (AREA)
Biochemistry (AREA)
Biophysics (AREA)
Biotechnology (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Wood Science & Technology (AREA)
Hematology (AREA)
Obesity (AREA)
Cardiology (AREA)
Toxicology (AREA)
Heart & Thoracic Surgery (AREA)
Gastroenterology & Hepatology (AREA)
General Engineering & Computer Science (AREA)
Endocrinology (AREA)
Urology & Nephrology (AREA)
Emergency Medicine (AREA)
Neurosurgery (AREA)
Physics & Mathematics (AREA)
Neurology (AREA)
Oncology (AREA)
Plant Pathology (AREA)

SK340-99A 1996-09-13 1997-08-29 Ptx sensitive g proteins, the production and use thereof SK34099A3 (en)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
DE19637518A DE19637518A1 (de)	1996-09-13	1996-09-13	PTX-sensitive G-Proteine, ihre Herstellung und Verwendung
PCT/EP1997/004709 WO1998011212A1 (de)	1996-09-13	1997-08-29	Ptx-sensitive g-proteine, ihre herstellung und verwendung

Publications (1)

Publication Number	Publication Date
SK34099A3 true SK34099A3 (en)	2000-05-16

Family

ID=7805651

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
SK340-99A SK34099A3 (en)	1996-09-13	1997-08-29	Ptx sensitive g proteins, the production and use thereof

Country Status (22)

Country	Link
US (1)	US6251853B1 (cs)
EP (1)	EP0931145A1 (cs)
JP (1)	JP2001501811A (cs)
KR (1)	KR20000036058A (cs)
CN (1)	CN1230222A (cs)
AU (1)	AU4619297A (cs)
BG (1)	BG103238A (cs)
BR (1)	BR9711475A (cs)
CA (1)	CA2265467A1 (cs)
CZ (1)	CZ73499A3 (cs)
DE (1)	DE19637518A1 (cs)
EA (1)	EA199900253A1 (cs)
EE (1)	EE9900092A (cs)
HU (1)	HUP9904110A3 (cs)
IL (1)	IL128746A0 (cs)
IS (1)	IS4987A (cs)
NO (1)	NO991227D0 (cs)
PL (1)	PL332417A1 (cs)
SK (1)	SK34099A3 (cs)
TR (1)	TR199900500T2 (cs)
WO (1)	WO1998011212A1 (cs)
ZA (1)	ZA978220B (cs)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
DE19619362A1 (de) *	1996-05-14	1997-11-20	Basf Ag	Verwendung einer Genveränderung im Gen für humanes G-Protein beta-3-Untereinheit zur Diagnostik von Erkrankungen
WO1999058669A1 (en) *	1998-05-11	1999-11-18	Axys Pharmaceuticals, Inc.	Rhoh genes and their uses
AU6079999A (en) *	1998-09-10	2000-04-03	Winfried Siffert	Gene modification in the gene for the die gbeta3-sub-unit of human g-protein
FR2803525B1 (fr) *	2000-01-06	2002-05-03	Sod Conseils Rech Applic	Inhibiteur de la transduction des signaux des proteines g heterotrimeriques associe a un agent anti-hypertenseur dans le traitement de l'hypertension arterielle
WO2001057246A1 (de) *	2000-02-03	2001-08-09	Winfried Siffert	VERWENDUNG EINER GENVERÄNDERUNG IM GEN FÜR DIE β3-UNTEREINHEIT DES HUMANEN G-PROTEINS

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US5587561A (en)	1995-07-28	1996-12-24	Budayr; Mahdi	Stethoscope shield
DE19619362A1 (de) *	1996-05-14	1997-11-20	Basf Ag	Verwendung einer Genveränderung im Gen für humanes G-Protein beta-3-Untereinheit zur Diagnostik von Erkrankungen

1996
- 1996-09-13 DE DE19637518A patent/DE19637518A1/de not_active Withdrawn
1997
- 1997-08-29 CA CA002265467A patent/CA2265467A1/en not_active Abandoned
- 1997-08-29 BR BR9711475A patent/BR9711475A/pt not_active Application Discontinuation
- 1997-08-29 CN CN97197854A patent/CN1230222A/zh active Pending
- 1997-08-29 JP JP10500960A patent/JP2001501811A/ja active Pending
- 1997-08-29 US US09/147,826 patent/US6251853B1/en not_active Expired - Fee Related
- 1997-08-29 TR TR1999/00500T patent/TR199900500T2/xx unknown
- 1997-08-29 EE EEP199900092A patent/EE9900092A/xx unknown
- 1997-08-29 EA EA199900253A patent/EA199900253A1/ru unknown
- 1997-08-29 EP EP97944809A patent/EP0931145A1/de not_active Withdrawn
- 1997-08-29 CZ CZ99734A patent/CZ73499A3/cs unknown
- 1997-08-29 IL IL12874697A patent/IL128746A0/xx unknown
- 1997-08-29 AU AU46192/97A patent/AU4619297A/en not_active Abandoned
- 1997-08-29 SK SK340-99A patent/SK34099A3/sk unknown
- 1997-08-29 HU HU9904110A patent/HUP9904110A3/hu unknown
- 1997-08-29 PL PL97332417A patent/PL332417A1/xx unknown
- 1997-08-29 KR KR1019997002058A patent/KR20000036058A/ko not_active Withdrawn
- 1997-08-29 WO PCT/EP1997/004709 patent/WO1998011212A1/de not_active Ceased
- 1997-09-12 ZA ZA978220A patent/ZA978220B/xx unknown
1999
- 1999-02-26 IS IS4987A patent/IS4987A/is unknown
- 1999-03-11 BG BG103238A patent/BG103238A/bg unknown
- 1999-03-12 NO NO991227A patent/NO991227D0/no not_active Application Discontinuation

Also Published As

Publication number	Publication date
IS4987A (is)	1999-02-26
PL332417A1 (en)	1999-09-13
DE19637518A1 (de)	1998-04-09
HUP9904110A3 (en)	2001-09-28
US6251853B1 (en)	2001-06-26
BG103238A (bg)	2000-06-30
NO991227L (no)	1999-03-12
AU4619297A (en)	1998-04-02
EP0931145A1 (de)	1999-07-28
CZ73499A3 (cs)	1999-07-14
CA2265467A1 (en)	1998-03-19
HUP9904110A2 (en)	2000-07-28
WO1998011212A1 (de)	1998-03-19
CN1230222A (zh)	1999-09-29
IL128746A0 (en)	2000-01-31
BR9711475A (pt)	1999-08-24
NO991227D0 (no)	1999-03-12
EA199900253A1 (ru)	1999-10-28
JP2001501811A (ja)	2001-02-13
ZA978220B (en)	1999-03-12
EE9900092A (et)	1999-10-15
KR20000036058A (ko)	2000-06-26
TR199900500T2 (xx)	1999-06-21

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