SK408491A3 - Gonadoliberin analogs with increased solubility method of their production, agents with their contents and their using - Google Patents

Gonadoliberin analogs with increased solubility method of their production, agents with their contents and their using Download PDF

Info

Publication number
SK408491A3
SK408491A3 SK4084-91A SK408491A SK408491A3 SK 408491 A3 SK408491 A3 SK 408491A3 SK 408491 A SK408491 A SK 408491A SK 408491 A3 SK408491 A3 SK 408491A3
Authority
SK
Slovakia
Prior art keywords
ser
trp
pro
arg
tyr
Prior art date
Application number
SK4084-91A
Other languages
English (en)
Slovak (sk)
Inventor
Wolfgang Konig
Jurgen K Sandow
Cenek Kolar
Original Assignee
Hoechst Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoechst Ag filed Critical Hoechst Ag
Publication of SK408491A3 publication Critical patent/SK408491A3/sk

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575—Hormones
    • C07K14/59—Follicle-stimulating hormone [FSH]; Chorionic gonadotropins, e.g.hCG [human chorionic gonadotropin]; Luteinising hormone [LH]; Thyroid-stimulating hormone [TSH]
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04—Linear peptides containing only normal peptide links
    • C07K7/23—Luteinising hormone-releasing hormone [LHRH]; Related peptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Endocrinology (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Diabetes (AREA)
  • Reproductive Health (AREA)
  • Toxicology (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Compounds Of Unknown Constitution (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Cosmetics (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
SK4084-91A 1986-10-09 1991-12-27 Gonadoliberin analogs with increased solubility method of their production, agents with their contents and their using SK408491A3 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19863634435 DE3634435A1 (de) 1986-10-09 1986-10-09 Analoga von gonadoliberin mit verbesserter loeslichkeit, verfahren zu deren herstellung, diese enthaltende mittel und ihre verwendung

Publications (1)

Publication Number Publication Date
SK408491A3 true SK408491A3 (en) 1995-07-11

Family

ID=6311399

Family Applications (1)

Application Number Title Priority Date Filing Date
SK4084-91A SK408491A3 (en) 1986-10-09 1991-12-27 Gonadoliberin analogs with increased solubility method of their production, agents with their contents and their using

Country Status (20)

Country Link
US (1) US5091367A (cs)
EP (1) EP0263521B1 (cs)
JP (1) JP2573625B2 (cs)
KR (1) KR960013387B1 (cs)
AT (1) ATE70278T1 (cs)
AU (1) AU595383B2 (cs)
CA (1) CA1314656C (cs)
CZ (1) CZ408491A3 (cs)
DE (2) DE3634435A1 (cs)
DK (1) DK171823B1 (cs)
ES (1) ES2055696T3 (cs)
FI (1) FI86863C (cs)
GR (1) GR3003927T3 (cs)
IE (1) IE60296B1 (cs)
IL (1) IL84121A (cs)
NZ (1) NZ222076A (cs)
PH (1) PH24731A (cs)
PT (1) PT85881B (cs)
SK (1) SK408491A3 (cs)
ZA (1) ZA877561B (cs)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK163689A (da) * 1988-04-08 1989-10-30 Sandoz Ag Peptidderivater
DE3842010A1 (de) * 1988-12-14 1990-06-21 Hoechst Ag Kompetitive gonadoliberin-antagonisten
ES2062628T3 (es) * 1990-08-04 1994-12-16 Hoechst Ag Antagonistas de gonadoliberina.
US5760000A (en) * 1994-05-13 1998-06-02 University Technologies International,Inc. Inhibition of liver cancer by the use of GnRH and GnRH analogs
GB2343182A (en) * 1998-10-27 2000-05-03 Ferring Bv Use of GnRH-II and analogues thereof for the treatment of osteoporosis
GB2344287A (en) * 1998-12-03 2000-06-07 Ferring Bv Controlled release pharmaceutical formulation
CN1301771A (zh) * 1999-12-27 2001-07-04 上海博德基因开发有限公司 一种新的多肽——人促性腺释放激素11和编码这种多肽的多核苷酸
CN1315354A (zh) * 2000-03-24 2001-10-03 上海博德基因开发有限公司 一种新的多肽——人促性腺释放激素12和编码这种多肽的多核苷酸
WO2005097158A1 (en) * 2004-03-29 2005-10-20 The Arizona Board Of Regents On Behalf Of The University Of Arizona Amphipathic glycopeptides

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NZ188987A (en) * 1977-11-30 1982-02-23 Salk Inst For Biological Studi Peptide analogues of luteinizing hormone releasing factor
FR2465486A1 (fr) * 1979-09-21 1981-03-27 Roussel Uclaf Nouvelle application utilisant la lh-rh ou des agonistes
US4409208A (en) * 1980-04-15 1983-10-11 The Salk Institute For Biological Studies GnRH antagonists
US4444759A (en) * 1982-07-26 1984-04-24 The Salk Institute For Biological Studies GnRH Antagonists II
DE3467173D1 (en) * 1983-08-16 1987-12-10 Akzo Nv Lh- rh antagonists

Also Published As

Publication number Publication date
ES2055696T3 (es) 1994-09-01
FI874401A0 (fi) 1987-10-07
AU595383B2 (en) 1990-03-29
ZA877561B (en) 1988-05-25
DK527187A (da) 1988-04-10
AU7945987A (en) 1988-04-14
ATE70278T1 (de) 1991-12-15
DK527187D0 (da) 1987-10-08
JP2573625B2 (ja) 1997-01-22
GR3003927T3 (cs) 1993-03-16
JPS6396198A (ja) 1988-04-27
FI86863C (fi) 1992-10-26
FI86863B (fi) 1992-07-15
IE872693L (en) 1988-04-09
IL84121A0 (en) 1988-03-31
EP0263521A3 (en) 1988-07-06
DK171823B1 (da) 1997-06-23
PH24731A (en) 1990-10-01
EP0263521B1 (de) 1991-12-11
FI874401L (fi) 1988-04-10
IL84121A (en) 1992-06-21
PT85881B (pt) 1990-07-31
DE3775156D1 (de) 1992-01-23
EP0263521A2 (de) 1988-04-13
CZ408491A3 (en) 1993-01-13
PT85881A (de) 1987-11-01
KR960013387B1 (ko) 1996-10-04
IE60296B1 (en) 1994-06-29
KR880005149A (ko) 1988-06-28
CA1314656C (en) 1993-03-16
US5091367A (en) 1992-02-25
NZ222076A (en) 1989-09-27
DE3634435A1 (de) 1988-04-14

Similar Documents

Publication Publication Date Title
US3853837A (en) Novel nonapeptide amide analogs of luteinizing hormone releasing factor
FI60553B (fi) Foerfarande foer framstaellning av ovulationsframkallande nonapeptidamidderivat
IE40257B1 (en) Nona- and decapeptide amides
JPS6218560B2 (cs)
US4690916A (en) Nona and decapeptide analogs of LHRH useful as LHRH antagonists
HU213098B (en) Process for producing decapeptides antagonistic to hormone for releazing lutheinizing-hormone and pharmaceutical compositions containing them as active components
HU181009B (en) Process for preparing angiotensin-ii analogues with antagonictic activity containing in position 1 sarcosyl,hydroxyacetyl or l-alpha-aminoxy-propionyl group and in positiona 8 esteric group
JPH09501177A (ja) 治療効果のあるペプチド誘導体
HUT50487A (en) Process for production of peptides
SK408491A3 (en) Gonadoliberin analogs with increased solubility method of their production, agents with their contents and their using
CA1057743A (en) Lh-rh analogues
US4005194A (en) Treatment of prostatic hyperplasia
JP3222050B2 (ja) 人工的アミノ酸
EP0000252B1 (en) Peptides, pharmaceutical compositions containing the peptides and a process for the preparation of the peptides
US4002738A (en) Treatment of specified neoplasias
JPS59112925A (ja) 鼻腔内投与用組成物及びその製造方法
HU181843B (en) Process for producing acth derivatives of psichopharmacological activity
JPS617297A (ja) 治療用ｌｈｒｈ類似体
US4034082A (en) Method to prevent reproduction in warm-blooded female animals with nonapeptides
US4083967A (en) Nona- and decapeptides
US3801561A (en) Derivatives of salmon thyrocalcitonin
JPH0631314B2 (ja) 新規なゴナドリベリン誘導体
EP0452447A1 (en) Reduced irreversible bombesin antagonists
PT92557B (pt) Processo para a preparacao de peptideos antagonistas da gonadoliberina competitivos e de composicoes farmaceuticas que os contem
IL34630A (en) Polypeptides and derivatives thereof,their production and pharmaceutical compositions containing them