SK6222002A3 - Peptides for treatment of erectile dysfunction - Google Patents

Peptides for treatment of erectile dysfunction Download PDF

Info

Publication number: SK6222002A3
Authority: SK; Slovakia
Prior art keywords: mrp; gab; peptide; lys; peptides
Prior art date: 1999-11-10

Application number

SK622-2002A

Other languages

English (en)

Slovak (sk)

Inventor

Antonio Argiolas

Romano Deghenghi

Original Assignee

Zentaris Ag

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1999-11-10

Filing date

2000-11-04

Publication date

2004-03-02

2000-11-04 Application filed by Zentaris Ag filed Critical Zentaris Ag

2004-03-02 Publication of SK6222002A3 publication Critical patent/SK6222002A3/sk

Links

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UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 claims description 3
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125000000430 tryptophan group Chemical group [H]N([H])C(C(=O)O*)C([H])([H])C1=C([H])N([H])C2=C([H])C([H])=C([H])C([H])=C12 0.000 description 1
230000002792 vascular Effects 0.000 description 1
XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 1
KNJNGVKTAFTUFL-OCMUWRIYSA-N ω-conotoxin Chemical compound N([C@@H](CO)C(=O)N[C@@H](CCCN=C(N)N)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCSC)C(=O)N[C@@H](CC=1C=CC(O)=CC=1)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@H]1C(N[C@@H](CSSC1)C(=O)N[C@@H]([C@@H](C)O)C(=O)NCC(=O)N[C@@H](CO)C(=O)N[C@@H]1C(N[C@@H](CCCN=C(N)N)C(=O)N[C@H](CO)C(=O)NCC(=O)N[C@H](CCCCN)C(=O)N[C@H](CSSC1)C(N)=O)=O)=O)C(=O)[C@@H]1CSSC[C@@H](N)C(=O)N[C@H](CCCCN)C(=O)NCC(=O)N[C@H](CCCCN)C(=O)NCC(=O)N[C@H](C)C(=O)N[C@@H](CCCCN)C(=O)N1 KNJNGVKTAFTUFL-OCMUWRIYSA-N 0.000 description 1
108091058550 ω-conotoxin Proteins 0.000 description 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
- C07K7/04—Linear peptides containing only normal peptide links
- C07K7/06—Linear peptides containing only normal peptide links having 5 to 11 amino acids
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
- A61K38/07—Tetrapeptides
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
- A61K38/08—Peptides having 5 to 11 amino acids
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/10—Drugs for genital or sexual disorders; Contraceptives for impotence
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/02—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link
- C07K5/0205—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link containing the structure -NH-(X)3-C(=0)-, e.g. statine or derivatives thereof
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
- C07K7/02—Linear peptides containing at least one abnormal peptide link
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
- A61K38/08—Peptides having 5 to 11 amino acids
- A61K38/095—Oxytocins; Vasopressins; Related peptides

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Organic Chemistry (AREA)
Medicinal Chemistry (AREA)
General Health & Medical Sciences (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Bioinformatics & Cheminformatics (AREA)
Animal Behavior & Ethology (AREA)
Molecular Biology (AREA)
Biophysics (AREA)
Biochemistry (AREA)
Veterinary Medicine (AREA)
Engineering & Computer Science (AREA)
Public Health (AREA)
Genetics & Genomics (AREA)
Pharmacology & Pharmacy (AREA)
Epidemiology (AREA)
Immunology (AREA)
Gastroenterology & Hepatology (AREA)
Crystallography & Structural Chemistry (AREA)
Reproductive Health (AREA)
Endocrinology (AREA)
Gynecology & Obstetrics (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Peptides Or Proteins (AREA)
Medicinal Preparation (AREA)

SK622-2002A 1999-11-10 2000-11-04 Peptides for treatment of erectile dysfunction SK6222002A3 (en)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
US09/437,147 US6211156B1 (en)	1999-11-10	1999-11-10	Peptides for treatment of erectile dysfunction
PCT/EP2000/010879 WO2001034171A2 (en)	1999-11-10	2000-11-04	Peptides for treatment of erectile dysfunction

Publications (1)

Publication Number	Publication Date
SK6222002A3 true SK6222002A3 (en)	2004-03-02

Family

ID=23735278

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
SK622-2002A SK6222002A3 (en)	1999-11-10	2000-11-04	Peptides for treatment of erectile dysfunction

Country Status (23)

Country	Link
US (1)	US6211156B1 (cs)
EP (1)	EP1246836A2 (cs)
JP (1)	JP2003513930A (cs)
KR (1)	KR20020058003A (cs)
CN (1)	CN1255426C (cs)
AR (1)	AR026434A1 (cs)
AU (1)	AU776994B2 (cs)
BG (1)	BG106735A (cs)
BR (1)	BR0015446A (cs)
CA (1)	CA2390854A1 (cs)
CZ (1)	CZ20021539A3 (cs)
HK (1)	HK1050205A1 (cs)
HU (1)	HUP0203181A3 (cs)
IL (1)	IL149200A0 (cs)
MX (1)	MXPA02004118A (cs)
NO (1)	NO20022101D0 (cs)
NZ (1)	NZ519062A (cs)
PL (1)	PL354613A1 (cs)
RU (1)	RU2264823C2 (cs)
SK (1)	SK6222002A3 (cs)
UA (1)	UA74170C2 (cs)
WO (1)	WO2001034171A2 (cs)
ZA (1)	ZA200203069B (cs)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
DE10344848A1 (de) *	2003-09-26	2005-04-14	Solvay Pharmaceuticals Gmbh	Amidomethyl-substituierte l-(Carboxyalkyl)-cyclopentylcarbonylamino-benzazepin-N-essigsäurederivate, Verfahren und Zwischenprodukte zu ihrer Herstellung und diese Verbindungen enhaltende Arzneimittel
RU2324703C1 (ru) *	2006-09-07	2008-05-20	Владимир Хацкелевич Хавинсон	Пептидное соединение, стимулирующее функцию половой системы, фармацевтическая композиция на его основе и способ ее применения
CN101302246B (zh) *	2007-05-09	2011-05-11	中国人民解放军军事医学科学院毒物药物研究所	黑色素皮质激素受体七肽类激动剂及其制备方法和用途
RU2404793C1 (ru)	2009-06-04	2010-11-27	Общество с ограниченной ответственностью Био Пептид	Стимулятор половой, сексуальной и репродуктивной функции
RU2507212C3 (ru)	2012-03-28	2022-05-04	Общество С Ограниченной Ответственностью "Айвикс"	Способ получения рекомбинантного пептида и полученный пептид
WO2017168174A1 (en)	2016-04-02	2017-10-05	N4 Pharma Uk Limited	New pharmaceutical forms of sildenafil
RU2626002C1 (ru)	2016-10-24	2017-07-21	Общество С Ограниченной Ответственностью "Айвикс"	Новая группа пептидов для лечения женской сексуальной дисфункции

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
DE3943519A1 (de) *	1989-04-27	1991-01-17	Stief Georg	Arzneimittel zur behandlung erektiler dysfunktionen
US5236904A (en) *	1989-09-18	1993-08-17	Senetek, Plc	Erection-inducing methods and compositions
US5872100A (en) *	1990-05-11	1999-02-16	Deghenghi; Romano	Peptides containing D-2-Alkyl-Tryptophan
WO1994022460A1 (en) *	1993-04-05	1994-10-13	University Patents, Inc.	Diagnosis and treatment of erectile dysfunction
ATE225806T1 (de) *	1994-09-27	2002-10-15	Bioscience Limited Ardana	D-2-alkyltryptophan enthaltende polypeptide mit wachstumhormon freisetzender aktivitaet
CA2158425C (en) *	1995-09-15	2003-01-28	Mac E. Hadley	Diagnostic and treatment of erectile dysfunction
IT1277113B1 (it) *	1995-12-20	1997-11-04	Romano Deghenghi	Composti oligopeptidici contenenti d-2-alchiltriptofano in grado di promuovere la liberazione dell'ormone della crescita
US5807985A (en) *	1996-06-11	1998-09-15	Deghenghi; Romano	Oligopeptide compounds containing D-2-alkyltryptophan capable of promoting the release of growth hormone
US6124263A (en) *	1998-11-16	2000-09-26	Asta Medica Ag	Treatment of tumors by administration of growth hormone releasing compounds and their antagonists
US5932548A (en) *	1998-06-03	1999-08-03	Deghenghi; Romano	Lysine containing peptides for treatment of heart disease

1999
- 1999-11-10 US US09/437,147 patent/US6211156B1/en not_active Expired - Fee Related
2000
- 2000-04-11 UA UA2002064655A patent/UA74170C2/uk unknown
- 2000-11-04 KR KR1020027005980A patent/KR20020058003A/ko not_active Abandoned
- 2000-11-04 CN CNB008155410A patent/CN1255426C/zh not_active Expired - Fee Related
- 2000-11-04 HK HK03101739.1A patent/HK1050205A1/zh unknown
- 2000-11-04 BR BR0015446-6A patent/BR0015446A/pt not_active IP Right Cessation
- 2000-11-04 EP EP00974507A patent/EP1246836A2/en not_active Withdrawn
- 2000-11-04 IL IL14920000A patent/IL149200A0/xx unknown
- 2000-11-04 PL PL00354613A patent/PL354613A1/xx not_active Application Discontinuation
- 2000-11-04 JP JP2001536168A patent/JP2003513930A/ja active Pending
- 2000-11-04 WO PCT/EP2000/010879 patent/WO2001034171A2/en not_active Ceased
- 2000-11-04 HU HU0203181A patent/HUP0203181A3/hu unknown
- 2000-11-04 CZ CZ20021539A patent/CZ20021539A3/cs unknown
- 2000-11-04 RU RU2002115662/15A patent/RU2264823C2/ru not_active IP Right Cessation
- 2000-11-04 MX MXPA02004118A patent/MXPA02004118A/es unknown
- 2000-11-04 NZ NZ519062A patent/NZ519062A/xx unknown
- 2000-11-04 AU AU12786/01A patent/AU776994B2/en not_active Ceased
- 2000-11-04 SK SK622-2002A patent/SK6222002A3/sk unknown
- 2000-11-04 CA CA002390854A patent/CA2390854A1/en not_active Abandoned
- 2000-11-10 AR ARP000105948A patent/AR026434A1/es unknown
2002
- 2002-04-18 ZA ZA200203069A patent/ZA200203069B/xx unknown
- 2002-05-02 NO NO20022101A patent/NO20022101D0/no unknown
- 2002-05-22 BG BG106735A patent/BG106735A/bg unknown

Also Published As

Publication number	Publication date
RU2002115662A (ru)	2004-01-27
JP2003513930A (ja)	2003-04-15
AU776994B2 (en)	2004-09-30
BR0015446A (pt)	2002-07-09
BG106735A (bg)	2003-02-28
ZA200203069B (en)	2002-11-27
IL149200A0 (en)	2002-11-10
PL354613A1 (en)	2004-02-09
NO20022101L (no)	2002-05-02
AU1278601A (en)	2001-06-06
EP1246836A2 (en)	2002-10-09
US6211156B1 (en)	2001-04-03
AR026434A1 (es)	2003-02-12
CZ20021539A3 (cs)	2003-08-13
CN1390230A (zh)	2003-01-08
UA74170C2 (uk)	2005-11-15
HUP0203181A2 (hu)	2003-02-28
HK1050205A1 (zh)	2003-06-13
WO2001034171A2 (en)	2001-05-17
RU2264823C2 (ru)	2005-11-27
HUP0203181A3 (en)	2003-11-28
NZ519062A (en)	2003-10-31
CN1255426C (zh)	2006-05-10
KR20020058003A (ko)	2002-07-12
CA2390854A1 (en)	2001-05-17
MXPA02004118A (es)	2003-02-12
NO20022101D0 (no)	2002-05-02
WO2001034171A3 (en)	2001-12-13

Publication	Publication Date	Title
FI92326C (fi)	1994-10-25	LHRH:n nonapeptidi- ja dekapeptidianalogeja, jotka ovat käyttökelpoisia LHRH:n antagonisteina
ES2203823T3 (es)	2004-04-16	Analogos heptapeptidicos de oxitocina.
US20020187938A1 (en)	2002-12-12	Ghrelin antagonists
TWI221845B (en)	2004-10-11	Peptide analogues
EP1082128B1 (en)	2005-12-28	Lysine containing peptides for treatment of heart disease
US6025471A (en)	2000-02-15	Diazaspiro, azepino and azabicyclo therapeutic peptides
Rivier et al.	1995	Gonadotropin-releasing hormone antagonists: novel members of the azaline B family
RU2240133C2 (ru)	2004-11-20	Способ снижения или ингибирования пролиферации онкогенных клеток и используемое в нем соединение (варианты)
CN104350064A (zh)	2015-02-11	修饰的吻素肽和其用途
JP3810083B2 (ja)	2006-08-16	成長因子の放出を促進し得る２−アルキルトリプトファン含有ペプチド化合物
KR100369104B1 (ko)	2003-06-12	성장호르몬의유리를촉진하는2-알킬트립토판함유-올리고펩티드화합물
JP2000510453A (ja)	2000-08-15	成長ホルモン遊離特性を有する化合物
SK6222002A3 (en)	2004-03-02	Peptides for treatment of erectile dysfunction
US7034050B2 (en)	2006-04-25	Pseudopeptides growth hormone secretagogues
ITMI951670A1 (it)	1997-01-28	Peptidi ciclici analoghi della somatostatina ad attivita' inibitrice dell'ormone della crescita
Oluyomi et al.	1994	Antinociceptive activity of peptides related to interleukin-1β-(193–195), Lys-Pro-Thr
EP1756142B1 (en)	2008-07-02	Pseudopeptides growth hormone secretagogues
HK1083068A (en)	2006-06-23	Lysine containing peptides for treatment of heart disease
HK1035863B (en)	2006-07-28	Lysine containing peptides for treatment of heart disease