SK630788A3 - 2,3-dihydro-2-oxo-1h-benzimidazol-1-carboxylic acid derivative, a process for manufacture thereof and pharmaceutical composition containing the same - Google Patents

2,3-dihydro-2-oxo-1h-benzimidazol-1-carboxylic acid derivative, a process for manufacture thereof and pharmaceutical composition containing the same Download PDF

Info

Publication number: SK630788A3
Authority: SK; Slovakia
Prior art keywords: oxo; group; dihydro; benzimidazole; methyl
Prior art date: 1987-09-23

Application number

SK6307-88A

Other languages

English (en)

Slovak (sk)

Other versions

SK278812B6 (sk

Inventor

Marco Turconi

Arturo Donetti

Rosamaria Micheletti

Annamaria Uberti

Massimo Nicola

Antonio Giachetti

Ernesto Montagna

Original Assignee

Boehringer Ingelheim Italia

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1987-09-23

Filing date

1988-09-22

Publication date

1998-03-04

1988-09-22 Application filed by Boehringer Ingelheim Italia filed Critical Boehringer Ingelheim Italia

1998-03-04 Publication of SK630788A3 publication Critical patent/SK630788A3/sk

1998-03-04 Publication of SK278812B6 publication Critical patent/SK278812B6/sk

Links

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/08—Drugs for disorders of the alimentary tract or the digestive system for nausea, cinetosis or vertigo; Antiemetics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/06—Antimigraine agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/20—Hypnotics; Sedatives
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D451/00—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof
- C07D451/02—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof containing not further condensed 8-azabicyclo [3.2.1] octane or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane; Cyclic acetals thereof
- C07D451/04—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof containing not further condensed 8-azabicyclo [3.2.1] octane or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane; Cyclic acetals thereof with hetero atoms directly attached in position 3 of the 8-azabicyclo [3.2.1] octane or in position 7 of the 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring system
- C07D451/06—Oxygen atoms
- C07D451/12—Oxygen atoms acylated by aromatic or heteroaromatic carboxylic acids, e.g. cocaine
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D451/00—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof
- C07D451/14—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof containing 9-azabicyclo [3.3.1] nonane ring systems, e.g. granatane, 2-aza-adamantane; Cyclic acetals thereof
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D453/00—Heterocyclic compounds containing quinuclidine or iso-quinuclidine ring systems, e.g. quinine alkaloids
- C07D453/02—Heterocyclic compounds containing quinuclidine or iso-quinuclidine ring systems, e.g. quinine alkaloids containing not further condensed quinuclidine ring systems
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D453/00—Heterocyclic compounds containing quinuclidine or iso-quinuclidine ring systems, e.g. quinine alkaloids
- C07D453/06—Heterocyclic compounds containing quinuclidine or iso-quinuclidine ring systems, e.g. quinine alkaloids containing isoquinuclidine ring systems
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/08—Bridged systems

Landscapes

Organic Chemistry (AREA)
Chemical & Material Sciences (AREA)
Health & Medical Sciences (AREA)
Bioinformatics & Cheminformatics (AREA)
Engineering & Computer Science (AREA)
General Health & Medical Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
General Chemical & Material Sciences (AREA)
Pharmacology & Pharmacy (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
Chemical Kinetics & Catalysis (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Biomedical Technology (AREA)
Neurology (AREA)
Neurosurgery (AREA)
Pain & Pain Management (AREA)
Anesthesiology (AREA)
Psychiatry (AREA)
Hospice & Palliative Care (AREA)
Otolaryngology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)
Plural Heterocyclic Compounds (AREA)
Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)

SK6307-88A 1987-09-23 1988-09-22 Derivát kyseliny 2,3-dihydro-2-oxo-1h-benzimidazol SK278812B6 (sk)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
IT8721997A IT1231413B (it)	1987-09-23	1987-09-23	Derivati dell'acido benzimidazolin-2-osso-1-carbossilico utili come antagonisti dei recettori 5-ht

Publications (2)

Publication Number	Publication Date
SK630788A3 true SK630788A3 (en)	1998-03-04
SK278812B6 SK278812B6 (sk)	1998-03-04

Family

ID=11189966

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
SK6307-88A SK278812B6 (sk)	1987-09-23	1988-09-22	Derivát kyseliny 2,3-dihydro-2-oxo-1h-benzimidazol

Country Status (28)

Country	Link
EP (1)	EP0309423B1 (cs)
JP (1)	JPH0631225B2 (cs)
KR (1)	KR960003604B1 (cs)
AT (1)	ATE107305T1 (cs)
BR (1)	BR1100514A (cs)
CA (1)	CA1337347C (cs)
CZ (1)	CZ279864B6 (cs)
DD (1)	DD285354A5 (cs)
DE (1)	DE3850203T2 (cs)
DK (1)	DK172226B1 (cs)
ES (1)	ES2054872T3 (cs)
FI (1)	FI89920C (cs)
HK (1)	HK142195A (cs)
HU (2)	HU200770B (cs)
IE (1)	IE63234B1 (cs)
IL (1)	IL87795A (cs)
IT (1)	IT1231413B (cs)
LV (1)	LV11035B (cs)
MX (1)	MX9203249A (cs)
NO (1)	NO169286C (cs)
NZ (1)	NZ226291A (cs)
PH (1)	PH29923A (cs)
PL (2)	PL151434B1 (cs)
SK (1)	SK278812B6 (cs)
SU (1)	SU1676451A3 (cs)
UA (1)	UA8022A1 (cs)
YU (1)	YU46925B (cs)
ZA (1)	ZA887083B (cs)

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IT1230881B (it) *	1989-06-20	1991-11-08	Angeli Inst Spa	Derivati del r(-) 3-chinuclidinolo
CA2030051C (en) *	1989-11-17	2001-08-07	Haruhiko Kikuchi	Indole derivatives
EP0436245A1 (en) *	1989-12-27	1991-07-10	Duphar International Research B.V	Substituted 3,4-annelated benzimidazol-2(1H)-ones
JP3122671B2 (ja) *	1990-05-23	2001-01-09	協和醗酵工業株式会社	複素環式化合物
US5192770A (en) *	1990-12-07	1993-03-09	Syntex (U.S.A.) Inc.	Serotonergic alpha-oxoacetamides
JP3026845B2 (ja) *	1991-02-20	2000-03-27	日清製粉株式会社	ピペリジン誘導体
IT1250629B (it) *	1991-07-04	1995-04-21	Boehringer Ingelheim Italia	Uso dei derivati dell'acido benzimidazolin-2-oxo-1-carbossilico.
GB9204565D0 (en) *	1992-03-03	1992-04-15	Smithkline Beecham Plc	Pharmaceuticals
JP2699794B2 (ja) *	1992-03-12	1998-01-19	三菱化学株式会社	チエノ〔３，２−ｂ〕ピリジン誘導体
JPH05310732A (ja) *	1992-03-12	1993-11-22	Mitsubishi Kasei Corp	シンノリン−３−カルボン酸誘導体
PH30413A (en) *	1992-03-26	1997-05-09	Boehringer Ingelheim Italia	Crystalline forms of endo-2,3-dihydro-n-(8-methyl)-8-azabicyclo-(3,2,1)oct-3-yl)-2-oxo-1h-benzimidazole-1-carboxamides
EP0641198A1 (en) *	1992-05-23	1995-03-08	Smithkline Beecham Plc	Medicaments for the treatment of anxiety
US5280028A (en) *	1992-06-24	1994-01-18	G. D. Searle & Co.	Benzimidazole compounds
US5521193A (en) *	1992-06-24	1996-05-28	G. D. Searle & Co.	Benzimidazole compounds
US5300512A (en) *	1992-06-24	1994-04-05	G. D. Searle & Co.	Benzimidazole compounds
JPH07508276A (ja) *	1992-06-27	1995-09-14	スミスクライン・ビーチャム・パブリック・リミテッド・カンパニー	５−ｈｔ↓４受容体アンタゴニスト含有医薬品
FR2694292B1 (fr) *	1992-07-29	1994-10-21	Esteve Labor Dr	Dérivés de benzimidazole-2-thione-, leur préparation et leur application en tant que médicament.
US5534521A (en) *	1993-06-23	1996-07-09	G. D. Searle & Co.	Benzimidazole compounds
GB9502582D0 (en) *	1995-02-10	1995-03-29	Smithkline Beecham Plc	Novel process
AU755117B2 (en) *	1999-05-12	2002-12-05	Sydney Gordon Low	A message processing system
TW200533348A (en)	2004-02-18	2005-10-16	Theravance Inc	Indazole-carboxamide compounds as 5-ht4 receptor agonists
TWI351282B (en)	2004-04-07	2011-11-01	Theravance Inc	Quinolinone-carboxamide compounds as 5-ht4 recepto
US7728006B2 (en)	2004-04-07	2010-06-01	Theravance, Inc.	Quinolinone-carboxamide compounds as 5-HT4 receptor agonists
US8309575B2 (en)	2004-04-07	2012-11-13	Theravance, Inc.	Quinolinone-carboxamide compounds as 5-HT4 receptor agonists
JP4129445B2 (ja) *	2004-06-15	2008-08-06	ファイザー・インク	ベンズイミダゾロンカルボン酸誘導体
JP5042028B2 (ja)	2004-11-05	2012-10-03	セラヴァンス，インコーポレーテッド	キノリノン−カルボキサミド化合物
DE602005016446D1 (de)	2004-11-05	2009-10-15	Theravance Inc	5-HT4-Rezeptoragonistenverbindungen
KR20070091665A (ko)	2004-12-22	2007-09-11	세라밴스 인코포레이티드	인다졸－카르복사미드 화합물
WO2006094063A1 (en)	2005-03-02	2006-09-08	Theravance, Inc.	Quinolinone compounds as 5-ht4 receptor agonists
ES2359673T3 (es)	2005-06-07	2011-05-25	Theravance, Inc.	Compuestos de benzoimidazolona-carboxamida como agonista del receptor 5-ht4.
MY143574A (en)	2005-11-22	2011-05-31	Theravance Inc	Carbamate compounds as 5-ht4 receptor agonists
KR20100046047A (ko) *	2007-07-27	2010-05-04	액테리온 파마슈티칼 리미티드	2-아자-비시클로[3.3.0]옥탄 유도체
EP2253316B1 (en)	2009-05-20	2013-08-14	INSERM (Institut National de la Santé et de la Recherche Médicale)	Serotonin 5-HT3 receptor antagonists for use in the treatment or prevention of an inner ear pathology with vestibular deficits
ES2664599T3 (es)	2009-05-20	2018-04-20	INSERM (Institut National de la Santé et de la Recherche Médicale)	Antagonistas del receptor 5-HT3 de serotonina para uso en el tratamiento de trastornos vestibulares lesionales
EP2701699B1 (en)	2011-04-28	2019-10-16	The Broad Institute, Inc.	Inhibitors of histone deacetylase
JP6337255B2 (ja)	2012-07-27	2018-06-06	ザブロードインスティテュート, インコーポレーテッドThe Broad Institute, Inc.	ヒストンデアセチラーゼの阻害剤
US9914717B2 (en)	2012-12-20	2018-03-13	The Broad Institute, Inc.	Cycloalkenyl hydroxamic acid derivatives and their use as histone deacetylase inhibitors
US20170166561A1 (en) *	2014-07-11	2017-06-15	Alpharmagen, Llc	Quinuclidine compounds for modulating alpha7-nicotinic acetylcholine receptor activity
JP2021510733A (ja)	2018-01-12	2021-04-30	ケーディーエーシーセラピューティクス，インコーポレーテッドＫｄａｃＴｈｅｒａｐｅｕｔｉｃｓ，Ｉｎｃ．	がんの処置のための選択的ヒストンデアセチラーゼ３（ｈｄａｃ３）インヒビターと免疫治療剤との組み合わせ

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Publication number	Priority date	Publication date	Assignee	Title
US4250176A (en) *	1976-12-21	1981-02-10	Janssen Pharmaceutica N.V.	Piperazine derivatives
EP0093488A3 (en) *	1982-03-18	1984-05-23	Beecham Group Plc	Nortropyl benzopyrrolinone compounds, process for their preparation and pharmaceutical compositions containing them
DE3687980T2 (de) *	1986-01-07	1993-06-17	Beecham Group Plc	Indolderivate mit einer azabicyclischen seitenkette, verfahren zu ihrer herstellung, zwischenprodukte und pharmazeutische zusammensetzungen.

1987
- 1987-09-23 IT IT8721997A patent/IT1231413B/it active
1988
- 1988-09-19 DE DE3850203T patent/DE3850203T2/de not_active Expired - Lifetime
- 1988-09-19 IL IL87795A patent/IL87795A/xx active Protection Beyond IP Right Term
- 1988-09-19 AT AT88830375T patent/ATE107305T1/de not_active IP Right Cessation
- 1988-09-19 ES ES88830375T patent/ES2054872T3/es not_active Expired - Lifetime
- 1988-09-19 PL PL1988274751A patent/PL151434B1/pl unknown
- 1988-09-19 EP EP88830375A patent/EP0309423B1/en not_active Expired - Lifetime
- 1988-09-19 DD DD88319929A patent/DD285354A5/de not_active IP Right Cessation
- 1988-09-19 PL PL1988279346A patent/PL152951B1/pl unknown
- 1988-09-20 CA CA000577840A patent/CA1337347C/en not_active Expired - Lifetime
- 1988-09-20 JP JP63236179A patent/JPH0631225B2/ja not_active Expired - Lifetime
- 1988-09-21 NZ NZ226291A patent/NZ226291A/xx unknown
- 1988-09-21 YU YU177888A patent/YU46925B/sh unknown
- 1988-09-22 NO NO884202A patent/NO169286C/no not_active IP Right Cessation
- 1988-09-22 DK DK526188A patent/DK172226B1/da not_active IP Right Cessation
- 1988-09-22 SU SU884356601A patent/SU1676451A3/ru active
- 1988-09-22 SK SK6307-88A patent/SK278812B6/sk unknown
- 1988-09-22 PH PH37579A patent/PH29923A/en unknown
- 1988-09-22 UA UA4356601A patent/UA8022A1/uk unknown
- 1988-09-22 FI FI884350A patent/FI89920C/fi not_active IP Right Cessation
- 1988-09-22 IE IE286988A patent/IE63234B1/en not_active IP Right Cessation
- 1988-09-22 HU HU884970A patent/HU200770B/hu not_active IP Right Cessation
- 1988-09-22 CZ CS886307A patent/CZ279864B6/cs not_active IP Right Cessation
- 1988-09-22 ZA ZA887083A patent/ZA887083B/xx unknown
- 1988-09-23 KR KR88012299A patent/KR960003604B1/ko not_active Expired - Fee Related
1992
- 1992-06-24 MX MX9203249A patent/MX9203249A/es unknown
1995
- 1995-02-17 LV LVP-95-33A patent/LV11035B/en unknown
- 1995-06-30 HU HU95P/P00691P patent/HU211566A9/hu unknown
- 1995-09-07 HK HK142195A patent/HK142195A/en not_active IP Right Cessation
1997
- 1997-05-13 BR BR1100514-9A patent/BR1100514A/pt active IP Right Grant

Also Published As

Publication number	Publication date
HK142195A (en)	1995-09-15
FI884350A0 (fi)	1988-09-22
NO169286C (no)	1992-06-03
EP0309423A2 (en)	1989-03-29
CZ279864B6 (cs)	1995-07-12
HU211566A9 (en)	1995-12-28
DD285354A5 (de)	1990-12-12
IL87795A0 (en)	1989-03-31
PL274751A1 (en)	1989-09-04
IE63234B1 (en)	1995-04-05
NO169286B (no)	1992-02-24
PL151434B1 (en)	1990-09-28
YU46925B (sh)	1994-06-24
PH29923A (en)	1996-09-16
DE3850203T2 (de)	1994-09-22
LV11035B (en)	1996-08-20
DK526188A (da)	1989-03-24
LV11035A (lv)	1996-02-20
FI89920B (fi)	1993-08-31
PL279346A1 (en)	1990-01-08
EP0309423B1 (en)	1994-06-15
CZ630788A3 (en)	1995-04-12
JPH01106882A (ja)	1989-04-24
DK172226B1 (da)	1998-01-12
SK278812B6 (sk)	1998-03-04
ZA887083B (en)	1990-05-30
CA1337347C (en)	1995-10-17
HUT48250A (en)	1989-05-29
KR890005105A (ko)	1989-05-11
JPH0631225B2 (ja)	1994-04-27
IT8721997A0 (it)	1987-09-23
PL152951B1 (en)	1991-02-28
KR960003604B1 (en)	1996-03-20
HU200770B (en)	1990-08-28
BR1100514A (pt)	2002-04-02
IT1231413B (it)	1991-12-04
DE3850203D1 (de)	1994-07-21
FI884350A7 (fi)	1989-03-24
YU177888A (en)	1990-06-30
SU1676451A3 (ru)	1991-09-07
UA8022A1 (uk)	1995-12-26
NZ226291A (en)	1991-05-28
DK526188D0 (da)	1988-09-22
AU2237888A (en)	1989-03-23
IE882869L (en)	1989-03-23
NO884202D0 (no)	1988-09-22
IL87795A (en)	1993-02-21
ES2054872T3 (es)	1994-08-16
MX9203249A (es)	1992-07-01
ATE107305T1 (de)	1994-07-15
AU610040B2 (en)	1991-05-09
EP0309423A3 (en)	1989-11-29
FI89920C (fi)	1993-12-10
NO884202L (no)	1989-03-28

Publication	Publication Date	Title
SK278812B6 (sk)	1998-03-04	Derivát kyseliny 2,3-dihydro-2-oxo-1h-benzimidazol
US5358954A (en)	1994-10-25	Benzimidazoline-2-oxo-1-carboxylic acid derivatives useful as 5-HT receptor antagonists
FI96686B (fi)	1996-04-30	Menetelmä farmakologisesti aktiivisten bentsofuusioitu-N-pitoisia heterosyklijohdoksia valmistamiseksi
DE60309057T2 (de)	2007-04-12	Azabicycloderivate als antagonisten des muscarinischen rezeptors
US5556851A (en)	1996-09-17	Cinnoline-3-carboxylic acid derivatives
US5047410A (en)	1991-09-10	Indolyl derivatives and their use as 5-HT3, receptor antagonists
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