SK9782000A3 - Macrolides, method for production thereof and pharmaceutical compositions on their base - Google Patents

Macrolides, method for production thereof and pharmaceutical compositions on their base Download PDF

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Publication number
SK9782000A3
SK9782000A3 SK978-2000A SK9782000A SK9782000A3 SK 9782000 A3 SK9782000 A3 SK 9782000A3 SK 9782000 A SK9782000 A SK 9782000A SK 9782000 A3 SK9782000 A3 SK 9782000A3
Authority
SK
Slovakia
Prior art keywords
alkyl
hydroxy
carbon atoms
hydrogen
optionally substituted
Prior art date
Application number
SK978-2000A
Other languages
English (en)
Slovak (sk)
Inventor
John Philip Dirlam
Hamish Alastair Irvin Mcarthur
Original Assignee
Pfizer Prod Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer Prod Inc filed Critical Pfizer Prod Inc
Publication of SK9782000A3 publication Critical patent/SK9782000A3/sk

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H17/00—Compounds containing heterocyclic radicals directly attached to hetero atoms of saccharide radicals
    • C07H17/04—Heterocyclic radicals containing only oxygen as ring hetero atoms
    • C07H17/08—Hetero rings containing eight or more ring members, e.g. erythromycins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7042—Compounds having saccharide radicals and heterocyclic rings
    • A61K31/7048—Compounds having saccharide radicals and heterocyclic rings having oxygen as a ring hetero atom, e.g. leucoglucosan, hesperidin, erythromycin, nystatin, digitoxin or digoxin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • A61P33/02—Antiprotozoals, e.g. for leishmaniasis, trichomoniasis, toxoplasmosis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H1/00—Processes for the preparation of sugar derivatives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H17/00—Compounds containing heterocyclic radicals directly attached to hetero atoms of saccharide radicals

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Biotechnology (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Epidemiology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
SK978-2000A 1998-01-02 1998-12-21 Macrolides, method for production thereof and pharmaceutical compositions on their base SK9782000A3 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US7034398P 1998-01-02 1998-01-02
PCT/IB1998/002099 WO1999035156A1 (en) 1998-01-02 1998-12-21 Novel macrolides

Publications (1)

Publication Number Publication Date
SK9782000A3 true SK9782000A3 (en) 2001-12-03

Family

ID=22094723

Family Applications (1)

Application Number Title Priority Date Filing Date
SK978-2000A SK9782000A3 (en) 1998-01-02 1998-12-21 Macrolides, method for production thereof and pharmaceutical compositions on their base

Country Status (34)

Country Link
US (2) US6472371B1 (is)
EP (1) EP1044207A1 (is)
JP (1) JP2002500230A (is)
KR (1) KR100352809B1 (is)
CN (1) CN1284081A (is)
AP (1) AP9801420A0 (is)
AR (4) AR014948A1 (is)
AU (1) AU756409B2 (is)
BG (1) BG104644A (is)
BR (1) BR9814601A (is)
CA (1) CA2316919C (is)
CO (1) CO4970821A1 (is)
CZ (1) CZ20002458A3 (is)
DZ (1) DZ2698A1 (is)
EA (1) EA200000594A1 (is)
GT (1) GT199800206A (is)
HR (1) HRP20000442A2 (is)
HU (1) HUP0100420A3 (is)
IL (1) IL137024A0 (is)
IS (1) IS5528A (is)
MA (1) MA24729A1 (is)
NO (1) NO20003347L (is)
NZ (1) NZ504986A (is)
OA (1) OA11438A (is)
PA (1) PA8465301A1 (is)
PE (1) PE20000049A1 (is)
PL (1) PL341642A1 (is)
SK (1) SK9782000A3 (is)
TN (1) TNSN98238A1 (is)
TW (1) TW520374B (is)
UY (2) UY25330A1 (is)
WO (1) WO1999035156A1 (is)
YU (1) YU41500A (is)
ZA (1) ZA9811939B (is)

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US6590083B1 (en) 1999-04-16 2003-07-08 Ortho-Mcneil Pharmaceutical, Inc. Ketolide antibacterials
US6451768B1 (en) 1999-04-16 2002-09-17 Kosan Biosciences, Inc. Macrolide antiinfective agents
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DE602005009381D1 (de) 2004-09-23 2008-10-09 Schering Plough Ltd Bekämpfung von parasiten in tieren durch verwendung neuer trifluormethansulfonanilidoximetherderivate
DE602005017419D1 (de) * 2004-11-19 2009-12-10 Schering Plough Ltd Kontrolle von parasiten bei tieren mittels verwendung von parasitiziden 2-phenyl-3-(1h-pyrrol-2-yl) acrylonitril-derivaten
EA011281B1 (ru) 2004-12-21 2009-02-27 Пфайзер Продактс Инк. Макролиды
AR054380A1 (es) * 2005-06-09 2007-06-20 Schering Plough Ltd Control de parasitos en animales con derivados de n- ((feniloxi) fenil) -1,1,1-trifluorometansulfonamida y de n-(fenilsulfanil) fenil) -1,1,1-trifluorometansulfonamida
US8119667B2 (en) * 2005-12-29 2012-02-21 Schering-Plough Animal Health Corporation Carbonates of fenicol antibiotics
US20070238700A1 (en) * 2006-04-10 2007-10-11 Winzenberg Kevin N N-phenyl-1,1,1-trifluoromethanesulfonamide hydrazone derivative compounds and their usage in controlling parasites
EP2102154A1 (en) * 2006-12-13 2009-09-23 Schering-Plough Ltd. Water-soluble prodrugs of chloramphenicol, thiamphenicol, and analogs thereof
MX2009006282A (es) * 2006-12-13 2009-06-23 Schering Plough Ltd Profarmacos solubles en agua de florfenicol y sus analogos.
TWI430995B (zh) 2007-06-26 2014-03-21 Du Pont 萘異唑啉無脊椎有害動物控制劑
EP2182945B1 (en) 2007-06-27 2015-08-05 E. I. du Pont de Nemours and Company Animal pest control method
WO2009064953A1 (en) * 2007-11-15 2009-05-22 Enanta Pharmaceuticals, Inc. Use of bridged macrolides or tylosin derivatives in treating inflammatory bowel diseases
TWI468407B (zh) 2008-02-06 2015-01-11 Du Pont 中離子農藥
JP2011529895A (ja) * 2008-07-30 2011-12-15 インターベツト・インターナシヨナル・ベー・ベー フロルフェニコール中間体として有用なオキサゾリン保護アミノジオール化合物を調製する方法
WO2011017347A2 (en) 2009-08-05 2011-02-10 E. I. Du Pont De Nemours And Company Mesoionic pesticides
UA107804C2 (xx) 2009-08-05 2015-02-25 Du Pont Суміші мезоіонних пестицидів
UA110924C2 (uk) 2009-08-05 2016-03-10 Е. І. Дю Пон Де Немур Енд Компані Мезоіонні пестициди
KR20120050467A (ko) 2009-08-05 2012-05-18 이 아이 듀폰 디 네모아 앤드 캄파니 메소이온성 살충제
EP2576523B1 (en) 2010-05-27 2016-01-13 E. I. du Pont de Nemours and Company Crystalline form of 4-[5 - [3 -chloro-5 -(trifluoromethyl)phenyl] -4,5 -dihydro-5 -(trifluoromethyl)-3 - isoxazolyl]-n-[2-oxo-2-[(2,2,2-trifluoroethyl)amino]ethyl]-1- naphthalenecarboxamide
WO2012087630A1 (en) 2010-12-20 2012-06-28 E.I. Du Pont De Nemours And Company Pyridine and pyrimidine compounds for controlling invertebrate
US20140011757A1 (en) * 2011-01-31 2014-01-09 Meiji Seika Pharma Co., Ltd. Novel macrolide derivative
AU2012273133A1 (en) 2011-06-20 2013-11-07 E. I. Du Pont De Nemours And Company Heterocyclic compounds for treating helminth infections
CN102260306B (zh) * 2011-07-22 2012-07-18 山东鲁抗舍里乐药业有限公司 一种制备泰拉霉素的方法
CN103958476A (zh) 2011-11-28 2014-07-30 纳幕尔杜邦公司 N-(4-喹啉基甲基)磺酰胺衍生物以及它们作为驱肠虫剂的用途
WO2013158422A1 (en) 2012-04-17 2013-10-24 E. I. Du Pont De Nemours And Company Heterocyclic compounds for controlling invertebrate pests
WO2014099837A1 (en) 2012-12-18 2014-06-26 E. I. Du Pont De Nemours And Company Sulfonamide anthelmintics
CN103965273B (zh) * 2013-08-23 2016-05-25 普莱柯生物工程股份有限公司 一种大环内酯类化合物
CN105669798B (zh) * 2013-08-23 2019-07-26 普莱柯生物工程股份有限公司 一种大环内酯类化合物

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Also Published As

Publication number Publication date
EP1044207A1 (en) 2000-10-18
NO20003347D0 (no) 2000-06-27
CN1284081A (zh) 2001-02-14
ZA9811939B (en) 2000-06-30
AU756409B2 (en) 2003-01-09
BG104644A (en) 2001-01-31
UY25330A1 (es) 2000-12-29
WO1999035156A1 (en) 1999-07-15
CA2316919C (en) 2004-10-26
AU1444799A (en) 1999-07-26
PL341642A1 (en) 2001-04-23
HRP20000442A2 (en) 2001-04-30
AR014948A1 (es) 2001-04-11
JP2002500230A (ja) 2002-01-08
NO20003347L (no) 2000-08-28
CA2316919A1 (en) 1999-07-15
KR100352809B1 (ko) 2002-11-01
UY25574A1 (es) 1999-09-27
WO1999035156B1 (en) 1999-10-21
MA24729A1 (fr) 1999-07-01
IS5528A (is) 2000-06-09
PE20000049A1 (es) 2000-02-07
HUP0100420A2 (hu) 2001-07-30
EA200000594A1 (ru) 2001-04-23
TW520374B (en) 2003-02-11
NZ504986A (en) 2003-03-28
CO4970821A1 (es) 2000-11-07
CZ20002458A3 (cs) 2001-10-17
US20040092459A1 (en) 2004-05-13
AR020851A2 (es) 2002-05-29
TNSN98238A1 (fr) 2005-03-15
AP9801420A0 (en) 1998-12-31
US6472371B1 (en) 2002-10-29
GT199800206A (es) 2000-06-21
US7015203B2 (en) 2006-03-21
HUP0100420A3 (en) 2003-07-28
KR20010024818A (ko) 2001-03-26
PA8465301A1 (es) 2000-09-29
DZ2698A1 (fr) 2003-03-29
YU41500A (sh) 2003-02-28
IL137024A0 (en) 2001-06-14
AR019787A2 (es) 2002-03-13
OA11438A (en) 2004-04-30
AR020551A2 (es) 2002-05-15
BR9814601A (pt) 2000-10-17

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