SMT201500020B - Somministrazione settimanale di 25-idrossi vitamina D3 per mantenere una elevata concentrazione sanguigna farmacocinetica stabile - Google Patents

Somministrazione settimanale di 25-idrossi vitamina D3 per mantenere una elevata concentrazione sanguigna farmacocinetica stabile

Info

Publication number: SMT201500020B
Authority: SM; San Marino
Prior art keywords: maintain; blood concentration; high stable; weekly administration; hydroxy vitamin
Prior art date: 2008-07-24

Application number

SM201500020T

Other languages

English (en)

Italian (it)

Inventor

Hector F Deluca

Lori A Plum

Margaret Clagett-Dame

Original Assignee

Wisconsin Alumni Res Found

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2008-07-24

Filing date

2015-01-26

Publication date

2015-03-05

2015-01-26 Application filed by Wisconsin Alumni Res Found filed Critical Wisconsin Alumni Res Found

2015-03-05 Publication of SMT201500020B publication Critical patent/SMT201500020B/xx

Links

JWUBBDSIWDLEOM-UHFFFAOYSA-N 25-Hydroxycholecalciferol Natural products C1CCC2(C)C(C(CCCC(C)(C)O)C)CCC2C1=CC=C1CC(O)CCC1=C JWUBBDSIWDLEOM-UHFFFAOYSA-N 0.000 title 1
JWUBBDSIWDLEOM-DCHLRESJSA-N 25-Hydroxyvitamin D3 Natural products C1(/[C@@H]2CC[C@@H]([C@]2(CCC1)C)[C@@H](CCCC(C)(C)O)C)=C/C=C1\C[C@@H](O)CCC1=C JWUBBDSIWDLEOM-DCHLRESJSA-N 0.000 title 1
JWUBBDSIWDLEOM-NQZHSCJISA-N 25-hydroxy-3 epi cholecalciferol Chemical compound C1([C@@H]2CC[C@@H]([C@]2(CCC1)C)[C@@H](CCCC(C)(C)O)C)=CC=C1C[C@H](O)CCC1=C JWUBBDSIWDLEOM-NQZHSCJISA-N 0.000 title 1
239000008280 blood Substances 0.000 title 1
210000004369 blood Anatomy 0.000 title 1
230000003442 weekly effect Effects 0.000 title 1

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/59—Compounds containing 9, 10- seco- cyclopenta[a]hydrophenanthrene ring systems
- A61K31/593—9,10-Secocholestane derivatives, e.g. cholecalciferol, i.e. vitamin D3
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/02—Nutrients, e.g. vitamins, minerals

Landscapes

Health & Medical Sciences (AREA)
Animal Behavior & Ethology (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Pharmacology & Pharmacy (AREA)
General Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Epidemiology (AREA)
Bioinformatics & Cheminformatics (AREA)
Engineering & Computer Science (AREA)
Organic Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Hematology (AREA)
General Chemical & Material Sciences (AREA)
Diabetes (AREA)
Obesity (AREA)
Chemical Kinetics & Catalysis (AREA)
Nutrition Science (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Medicinal Preparation (AREA)

SM201500020T 2008-07-24 2015-01-26 Somministrazione settimanale di 25-idrossi vitamina D3 per mantenere una elevata concentrazione sanguigna farmacocinetica stabile SMT201500020B (it)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
US8322308P	2008-07-24	2008-07-24
PCT/US2009/051664 WO2010011906A1 (fr)	2008-07-24	2009-07-24	Administration hebdomadaire de 25-hydroxy vitamine d3 pour maintenir une concentration sanguine à pharmacocinétique stable élevée

Publications (1)

Publication Number	Publication Date
SMT201500020B true SMT201500020B (it)	2015-03-05

Family

ID=41570618

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
SM201500020T SMT201500020B (it)	2008-07-24	2015-01-26	Somministrazione settimanale di 25-idrossi vitamina D3 per mantenere una elevata concentrazione sanguigna farmacocinetica stabile

Country Status (13)

Country	Link
US (4)	US8759328B2 (fr)
EP (1)	EP2321273B1 (fr)
JP (2)	JP6095891B2 (fr)
AU (1)	AU2009273889B2 (fr)
CA (1)	CA2731382C (fr)
DK (1)	DK2321273T3 (fr)
ES (1)	ES2525180T3 (fr)
HR (1)	HRP20150093T1 (fr)
PL (1)	PL2321273T3 (fr)
PT (1)	PT2321273E (fr)
SI (1)	SI2321273T1 (fr)
SM (1)	SMT201500020B (fr)
WO (1)	WO2010011906A1 (fr)

Families Citing this family (21)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
ES2593047T3 (es)	2006-02-03	2016-12-05	Opko Renal, Llc	Tratamiento de la insuficiencia y deficiencia de vitamina D con 25-hidroxivitamina D2 y 25-hidroxivitamina D3
ES2670029T3 (es)	2006-06-21	2018-05-29	Opko Ireland Global Holdings, Ltd.	Terapia usando agente de repleción de la vitamina D y agente de reemplazo de la hormona de la vitamina D
US8592401B2 (en)	2007-04-25	2013-11-26	Proventiv Therapeutics, Llc	Methods and compounds for vitamin D therapy
KR20190028822A (ko)	2007-04-25	2019-03-19	사이토크로마 인코포레이티드	비타민 ｄ 화합물과 밀랍성 담체를 포함하는 경구 조절성 방출 조성물
US11752158B2 (en)	2007-04-25	2023-09-12	Eirgen Pharma Ltd.	Method of treating vitamin D insufficiency and deficiency
HUE073014T2 (hu)	2007-04-25	2025-12-28	Opko Renal Llc	Eljárás a másodlagos hyperparathyreoidismus biztonságos és hatékony kezelésére és megelõzésére krónikus vesebetegség esetén
EP2281058B1 (fr)	2008-04-02	2016-06-29	Opko Ireland Global Holdings, Ltd.	Procédés, compositions, utilisations, et kits utiles pour la carence en vitamine d et des troubles associés
EP2321273B1 (fr) *	2008-07-24	2014-11-19	Wisconsin Alumni Research Foundation	Administration hebdomadaire de 25-hydroxy vitamine d3 pour maintenir une concentration sanguine à pharmacocinétique stable élevée
WO2011123476A1 (fr)	2010-03-29	2011-10-06	Cytochroma Inc.	Procédés et compositions pour réduction de taux d'hormone parathyroïde
US10055727B2 (en)	2012-11-05	2018-08-21	Mfoundry, Inc.	Cloud-based systems and methods for providing consumer financial data
KR101847947B1 (ko)	2013-03-15	2018-05-28	옵코 아이피 홀딩스 Ⅱ 인코포레이티드	안정화되고 변형된 비타민 ｄ 방출 제형
US20140296190A1 (en) *	2013-03-27	2014-10-02	Dsm Ip Assets B.V.	Marketing the use of 25-hydroxyvitamin d3 to enhance cognition
WO2015102996A1 (fr) *	2013-12-31	2015-07-09	Grasso Frank J	Dose à charge très élevée
US10220047B2 (en) *	2014-08-07	2019-03-05	Opko Ireland Global Holdings, Ltd.	Adjunctive therapy with 25-hydroxyvitamin D and articles therefor
EP3053598A1 (fr)	2015-02-06	2016-08-10	Faes Farma, S.A.	Capsules molles de calcifédiol
WO2017126512A1 (fr) *	2016-01-20	2017-07-27	国立大学法人島根大学	Lampe frontale pour personnel soignant
JP7032322B2 (ja)	2016-03-28	2022-03-08	オプコアイルランドグローバルホールディングスリミテッド	ビタミンｄ治療法
CN108383767B (zh) *	2018-02-06	2020-03-24	山东海能生物工程有限公司	25-羟基胆钙化醇一水合物晶体及其制备方法以及使用其的微乳液
CN120694962A (zh) *	2020-05-31	2025-09-26	艾尔金制药有限公司	硬胶囊剂型和其用途
WO2022006446A1 (fr) *	2020-07-02	2022-01-06	The Uab Research Foundation	Compositions et méthodes de traitement d'affections
WO2022224001A1 (fr) *	2021-04-22	2022-10-27	Faes Farma, S.A.	Schéma posologique universel de 25-hydroxy vitamine d3

Family Cites Families (14)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US3607888A (en)	1969-08-07	1971-09-21	Wisconsin Alumni Res Found	25-hydroxytachysterol3 25-hydroxydihydrotachysterol3 and methods for preparing same
EP0660718B1 (fr) *	1992-09-15	1999-12-08	THYS-JACOBS, Susan	Procede de traitement de la symptomatologie du syndrome premenstruel par la vitamine d ou la vitamine d et le calcium combines
US7632518B2 (en) *	2002-01-15	2009-12-15	Dsm Ip Assets B.V.	25-hydroxy vitamin D3 compositions
CA2480814A1 (fr) *	2002-04-05	2003-10-23	Merck & Co., Inc.	Procede d'inhibition de resorption osseuse a l'aide d'une formulation a base d'alendronate et de vitamine d
US20050101576A1 (en) *	2003-11-06	2005-05-12	Novacea, Inc.	Methods of using vitamin D compounds in the treatment of myelodysplastic syndromes
KR20060015316A (ko) *	2003-05-28	2006-02-16	넥타르 테라퓨틱스	아미노산 및/또는 인지질로 부분 또는 완전 코팅된수불용성 활성제 미립자의 제조를 위한 알코올성 수용액의분무 건조법
ES2593047T3 (es) *	2006-02-03	2016-12-05	Opko Renal, Llc	Tratamiento de la insuficiencia y deficiencia de vitamina D con 25-hidroxivitamina D2 y 25-hidroxivitamina D3
ES2670029T3 (es) *	2006-06-21	2018-05-29	Opko Ireland Global Holdings, Ltd.	Terapia usando agente de repleción de la vitamina D y agente de reemplazo de la hormona de la vitamina D
US8592401B2 (en) *	2007-04-25	2013-11-26	Proventiv Therapeutics, Llc	Methods and compounds for vitamin D therapy
US11752158B2 (en) *	2007-04-25	2023-09-12	Eirgen Pharma Ltd.	Method of treating vitamin D insufficiency and deficiency
KR20190028822A (ko) *	2007-04-25	2019-03-19	사이토크로마 인코포레이티드	비타민 ｄ 화합물과 밀랍성 담체를 포함하는 경구 조절성 방출 조성물
JP5593550B2 (ja) *	2008-02-13	2014-09-24	ディーエスエムアイピーアセッツビー．ブイ．	ヒトの筋生理に影響を与えるための２５−ヒドロキシビタミンｄ３の使用
EP2321273B1 (fr) *	2008-07-24	2014-11-19	Wisconsin Alumni Research Foundation	Administration hebdomadaire de 25-hydroxy vitamine d3 pour maintenir une concentration sanguine à pharmacocinétique stable élevée
WO2011123476A1 (fr) *	2010-03-29	2011-10-06	Cytochroma Inc.	Procédés et compositions pour réduction de taux d'hormone parathyroïde

2009
- 2009-07-24 EP EP09801055.6A patent/EP2321273B1/fr active Active
- 2009-07-24 DK DK09801055.6T patent/DK2321273T3/en active
- 2009-07-24 ES ES09801055.6T patent/ES2525180T3/es active Active
- 2009-07-24 HR HRP20150093AT patent/HRP20150093T1/hr unknown
- 2009-07-24 PT PT98010556T patent/PT2321273E/pt unknown
- 2009-07-24 PL PL09801055T patent/PL2321273T3/pl unknown
- 2009-07-24 WO PCT/US2009/051664 patent/WO2010011906A1/fr not_active Ceased
- 2009-07-24 CA CA2731382A patent/CA2731382C/fr active Active
- 2009-07-24 AU AU2009273889A patent/AU2009273889B2/en active Active
- 2009-07-24 SI SI200931127T patent/SI2321273T1/sl unknown
- 2009-07-24 JP JP2011520222A patent/JP6095891B2/ja active Active
- 2009-07-24 US US12/672,190 patent/US8759328B2/en active Active
2013
- 2013-03-11 US US13/793,393 patent/US20140100203A1/en not_active Abandoned
2015
- 2015-01-26 SM SM201500020T patent/SMT201500020B/xx unknown
- 2015-09-03 US US14/844,998 patent/US20150374722A1/en not_active Abandoned
2016
- 2016-11-28 JP JP2016230604A patent/JP6375353B2/ja not_active Expired - Fee Related
2020
- 2020-05-19 US US16/878,073 patent/US20200281947A1/en not_active Abandoned

Also Published As

Publication number	Publication date
US20150374722A1 (en)	2015-12-31
US8759328B2 (en)	2014-06-24
EP2321273A1 (fr)	2011-05-18
EP2321273B1 (fr)	2014-11-19
PL2321273T3 (pl)	2015-05-29
US20140100203A1 (en)	2014-04-10
CA2731382C (fr)	2020-04-28
EP2321273A4 (fr)	2011-11-30
AU2009273889A1 (en)	2010-01-28
JP6095891B2 (ja)	2017-03-15
SI2321273T1 (sl)	2015-03-31
ES2525180T3 (es)	2014-12-18
AU2009273889B2 (en)	2013-01-31
JP6375353B2 (ja)	2018-08-15
JP2017061545A (ja)	2017-03-30
US20200281947A1 (en)	2020-09-10
JP2011529081A (ja)	2011-12-01
WO2010011906A1 (fr)	2010-01-28
CA2731382A1 (fr)	2010-01-28
PT2321273E (pt)	2014-12-29
US20110105444A1 (en)	2011-05-05
HRP20150093T1 (hr)	2015-03-27
DK2321273T3 (en)	2015-02-16

Publication	Publication Date	Title
SMT201500020B (it)	2015-03-05	Somministrazione settimanale di 25-idrossi vitamina D3 per mantenere una elevata concentrazione sanguigna farmacocinetica stabile
HUS1900031I1 (hu)	2019-07-29	Hatóanyagok légúti beadása
IL262567B (en)	2021-08-31	Concentrated therapeutic phospholipid compositions
PT2451437T (pt)	2017-01-17	Preparações aquosas de insulina contendo metionina
IL217014A (en)	2016-04-21	Use of an antisense compound for the preparation of a medicament for modulation of smn2 splicing in a subject
EP2352542A4 (fr)	2012-05-02	Administration sélective de médicament dans une lumière
IT1396937B1 (it)	2012-12-20	Formulazioni di bisfosfonati e vitamina d idonee alla somministrazione intermittente per via intramuscolare e sottocutanea
DK2464343T3 (da)	2019-01-02	System til indgivelse af oftalmisk medicin indeholdende phospholipid og kolesterol
DK2254590T3 (da)	2013-01-28	Fremgangsmåder og præparater til oral administration af insulin
HRP20160807T1 (hr)	2016-08-26	Visoko koncentrirane farmaceutske formulacije koje sadrže protutijelo anti-cd20
EP2387394A4 (fr)	2012-09-19	Administration transdermique de tamsulosine
HUE055250T2 (hu)	2021-11-29	Nátriumnitritet tartalmazó gyógyászati készítmények
PL2399606T3 (pl)	2013-09-30	Sposób wytwarzania stabilnej termicznie kompozycji farmaceutycznej zawierającej nośnik tlenowy
BRPI0914549A2 (pt)	2015-12-15	produção, formulação de usos de formulações estáveis de proteína harpina líquidas
EP2427211A4 (fr)	2013-05-01	Formulations stables à concentration protéique élevée d'anticorps anti-tnf-alpha humain
PT2706982T (pt)	2018-03-08	Formas farmacêutica de administração por via nasal contendo naloxona
DK2506712T3 (da)	2019-06-03	Morfinanderivater til behandling af lægemiddeloverdosering
IL232258A0 (en)	2014-06-30	Dermal delivery compositions and methods
BRPI1012246A2 (pt)	2016-03-29	composição farmacêutica contendo um fármaco e sirna
PL2672973T3 (pl)	2021-06-28	Schemat podawania nitrokatecholi
LT2603232T (lt)	2020-01-27	Stabilios linaklotido vaisto formos
SMT201600341B (it)	2016-11-10	Soluzione per somministrazione orale
DK3005986T3 (da)	2021-11-22	Infusion af lægemidler
EP2781154A4 (fr)	2015-09-23	Structure contenant un agent médicamenteux volatile
EP2442821A4 (fr)	2013-07-31	Administration sûre de desmopressine